Hyperbaric oxygen therapy (HBOT) is a medical treatment involving the inhalation of 100% oxygen at pressures greater than normal atmospheric pressure, effective for various conditions such as carbon monoxide poisoning, decompression sickness, and chronic wounds. The therapy operates through mechanisms like hyper oxygenation, vasoconstriction, and angiogenesis to enhance healing and combat infections. HBOT is administered in specialized chambers, including portable, monoplace, and multiplace types, and training for practitioners is available in India.

1. Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy
is often referred to as:
HBOT
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2. BRIEF HISTORY OF HBOT
 1662 - British physician to treat pulmonary disease and help with digestion.
 1891 - Doctors in U.S. began using hyperbaric oxygen therapy to treat nervous disorders
 1895 - Was found to be effective in treating carbon monoxide poisoning.
 1928 - A five story having 60 rooms chamber for $1 million in Ohio by Dr. Cunningham
 1934 - A U.S. Naval officer found it to be effective in treating decompression sickness.
 1961 - Hyperbaric oxygen therapy was found to be effective in treating gas gangrene.
 1963 - The first International Congress on Hyperbaric Medicine convened in USA
 1966 - Hyperbaric oxygen therapy was found to be effective in treating stroke patients.
 1970 - Hyperbaric oxygen therapy was found to be effective in treating multiple sclerosis.
 1988 - The International Society of Hyperbaric Medicine was founded.
 2000 -Hyperbaric medicine was approved by the American Board of Medical Specialties
as a sub-speciality of emergency and preventative medicine.
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3. Hyperbaric Oxygen Therapy
Humour
“First tried on Human ….
now being successfully used on animals. ”
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4. HYPERBARIC
Hyper = More or increased
Baric = Related to Pressure
More Pressure
Word “Hyperbaric” is derived from Hebrew word for “More Pressure”
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5. “Hyperbaric” is More Pressure
Than what pressure ?
Related to which pressure?
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6. More Pressure
Related to Atmospheric Pressure
Atmospheric pressure is the
pressure exerted at sea level.
This pressure is referred to as
One Atmospheric Pressure = 1 ATA
ATA ( Atmospheric Absolute )
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7. Henry’s Law
Increase in atmospheric pressure allows
more gas to be dissolved into any given liquid.
Increase in more oxygen pressure
allows more oxygen to be dissolved in body fluids.
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8. What is
Hyperbaric Medicine ?
The medical use of
Oxygen
At
higher pressure
than the atmospheric pressure
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9. What is
Hyperbaric Oxygen Therapy ?
(HBOT)
Intermittant medical treatment with
100 % oxygen
at a
pressure greater
than the normal atmospheric pressure
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10. MECHANISM OF ACTION
1. Hyper oxygenation:
Breathing room air renders 21% oxygen at 1 ATA.
Hyperbaric chamber provides up to 20 times 100%
oxygen to all tissues within the body.

11. MECHANISM OF EFFECT
2. Direct Pressure to Oxygen Molecules:
Normally only the red blood cells are capable of
transporting oxygen.
During HBOT, Oxygen molecules become more soluble obeying
the scientific principles of Henry’s Universal Gas Law.
Oxygen crosses cell membranes and enter all of the body’s
fluid systems, including plasma, synovial, lymphatic,
interstitial (between cells) and cerebrospinal fluids.
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12. MECHANISM OF ACTION
3. Mechanical effect:
Any free gas trapped in the body will decrease in
volume as the pressure on it increases”
Successfully applied to air embolism and
decompression sickness
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13. MECHANISM OF ACTION:
4. Gas Wash out effect:
The flooding of the body with any one gas tends to "wash
out" all others.
Treatment for CO intoxication
and cyanide poisoning
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14. MECHANISM OF ACTION
5. Vasoconstriction:
Causes vasoconstriction without creating
hypoxia which decreases edema
Useful in burns, crush injuries,
interstitial bleeding, Acute brain and
spinal cord injuries
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15. MECHANISM OF ACTION
6. Bacteriostasis
Organisms that cannot survive in an oxygen rich
environment are bacteria, fungi and viruses
White blood cells (leukocytes) become
supercharged with Oxygen in the battle against
bacteria responsible for causing infection
and illness.
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16. MECHANISM OF ACTION
7. Superoxide Dismutase (SOD) Stimulation
A Surge of Antioxidant Capabilities:
Hyperbaric Oxygen stimulates superoxides
( SOD production)
Helps the body to rid itself of the byproducts of
inflammation and damaging free radicals.
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17. MECHANISM OF ACTION
8. Angiogenesis
The Formation of New Blood Vessels:
Stimulates the growth of new capillaries (angiogenesis)
building a new collateral to serve injured and healthy
tissues alike.
Neovascularization is helpful for reaching tissues and
organs that have restricted blood flow to ischemic areas.
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18. MECHANISM OF ACTION
9. Fibroplast and Collagen Production
Fibroblast, Collagen reproduction and growth
are aided by the added availability of increased
oxygen provided during hyperbaric conditions.
Plays a critical role in wound healing.
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19. MECHANISM OF ACTION
10. Osteoblast and Osteoclast Production:
Stimulate and increase production of cells like
osteoblasts and osteoclasts
Faster regeneration of bone.
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20. 14 Approved Indications
by Undersea Hyperbaric medicine Society (UHMS)
1. Air or Gas Embolism
2. Carbon Monoxide Poisoning • Carbon Monoxide Poisoning Complicated
By Cyanide Poisoning
3. Clostridial Myositis and Myonecrosis (Gas Gangrene)
4. Crush Injury, Compartment Syndrome and Other Acute Traumatic
Ischemias
5. Decompression Sickness
6. Arterial Insufficiencies: Central Retinal Artery Occlusion, •
Enhancement of Healing In Selected Problem Wounds
7. Severe Anemia
8. Intracranial Abscess
9. Necrotizing Soft Tissue Infections
10. Osteomyelitis (Refractory)
11. Delayed Radiation Injury (Soft Tissue and Bony Necrosis)
12. Compromised Grafts and Flaps
13. Acute Thermal Burn Injury
14. Idiopathic Sudden Sensorineural Hearing Loss
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21. OFF LABEL INDICATIONS
NEUROSURGERY
Gas Gangrene
Non Healing Wounds,
Ulcers, Diabetic Foot
*Burns *Air and Gas
Embolism *Blast Injuries
*Deep Vein Thrombosis
*Frostbite *Peripheral
Vascular Ulcers-Arterial
(Atherosclerosis), Decubitus
(Bed Sores), Neuropathy
Related (Diabetes), Various
(DVT) *Burgers Disease
NEUROLOGY
Acute and chronic stroke
*Vegetative Coma following
closed head injury *Cerebral
edema due brain tumours *
Trauma and toxic
encephalopathy * Multiple
Scelorosis * Migraine *
Cluster Headache *Cranial
Nerve syndromes like
Trigeminal Neuralgia, Optic
Neuritis, Sudden Deafness
*Brain stem syndrome
*Retinal Artery occlusion

22. OFF LABEL INDICATIONS
ORTHOPAEDICS
*Crush Injuries
*Compartment (Clostridial)
*Myonecrosis (Clostridial) *Acute
and Chronic Osteomyelitis,
*Acute Necrotizing Fascitis
*Bone Grafting
*Tendon and ligament injuries
*Amputation Stump infections etc
*Fracture /Non Union
*Oedema Under Cast
MEDICINE
Poisioning-Carbon Monoxide,
Hydrogen Sulphide, Peyote &
Cyanide
*Near Drowning, hanging,
Electrocution
*Ileus
* Exceptional blood loss-anaemia
*Decompression Sickness
*Pseudomembranous Colitis
*Rheumatoid Arthritis (Acute)
*Sickle Cell Crisis and Haematuria
*Myocardial infarction *Post
Cardiotomy Low Output Failure
*Immune System Enhancement
*Peptic Ulcers

23. OFF LABEL INDICATIONS
OPTHALMOLOGY
*Diabetic Retinopathy
*Retinal Vein Thrombosis
*Retinitis Pigmentosa
*Retina Artery Occlusion
*Toxic Amblyopia
*Corneal Disorders
*Glaucoma
*Neovascularisation of Retina
*Vascular Insufficiency
PLASTIC SURGERY
*Compromised Skin Flaps and
Grafts
*Speed Healing With Less Scar
ENT
Sudden Deafness
* Acoustic Trauma
*Meneire’s Desease
* Chronic Lyringitis
SKIN
*Toxic Epidermal Necrolysis
(Lyells Syndrome)
* Lepromatous Leprosy
* Refractory Mycose

24. Hyperbaric Oxygen Therapy
How
Hyperbaric Oxygen Therapy
Is Administered ?
* Oxygen as a drug
* Hyperbaric chamber as a device
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25. Types of
Hyperbaric Oxygen Therapy Chambers
1) Portable Hyperbaric Chambers
2) Monoplace Hyperbaric Chambers
3) Multiplace Hyperbaric Chambers
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26. Portable Hyperbaric Chamber
Child receiving treatment Attributes:
 Made of inflatable Bags with zippers
 Maximum pressure upto 1.3/1.5 ATA
 1 Adult & 1 Child
 Allows self and home treatment.
 Portable, can be carried if needed.
 Oxygen is supplied by oxygen
concentrator
 Low costs and limited application
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27. Monoplace HBOT Chamber
Patient receiving treatment Attributes
 Accommodates only a single person
at a time.
 Pressurized to upto 3 ATA with
100% oxygen
 Access to patient through intercom
communication.
 Patient entertainment systems -TV
/ Video is mounted on top
 Patient monitoring systems can be
hooked
 Lower cost
 Mobile
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28. Monoplace HBOT chamber
Chamber shown with the Door
open and Trolley
Patient being slided with the top
of the trolley

29. Monoplace Hyperbaric Chamber

30. Multiplace HBOT Chamber
 Accommodates patients / healthcare
personnel from 4 – 20 in numbers.
 Pressurised with medical breathing air
upto 6 ATA
 Breath 100% oxygen through head tent
or face mask
 Patient monitors and ventilators can be
interfaced for the Critically ill
 Medicines can be passed through
special openings during treatment
 Intercom communication, Internal
Entertainment system like TV / video
 Needs larger space & fixed systems
 High cost
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31. MULTIPLACE HYPERBARIC CHAMBER
 Internal view of patients receiving treatment with
medical attendants inside the chamber

32. MONO & MULTIPLACE CHAMBER
ILLUSTRATED PICTURES
Monoplace Chamber Multiplace Chamber

33. HBOT
1.) HBO therapy follows Physiological Principles and the
Laws of physics
2.) HBO is Currently indicated for 14 diseases and
supported by the literature
3.) Used for many off label indications internationally based
on clinical research.
4.) Evidence includes testimonial, case reports and studies.
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34. HBOT TRAINING
We arrange training to your Technician Nurse &
Physician at our center in India.
Training will be imparted by
Internationally certified
Hyperbaric Physician and Technician.
Ask us for further details:
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Cell: 9769 484 123 / 9769 006 123 Telf : 91-22-65 655 123
Email: indiahbot@gmail.com / info@indiahbot.com
www.indiahbot.com
www.indiahbot.blogspot.com
Bombay, India

35. BIRD MEDICAL DEVICES
Thanks.
Dedicated to promoting
Affordable
Hyperbaric Oxygen Therapy chambers In
India.
Cell: 9769 484 123 / 9769 006 123
Telf : 91-22-65 655 123
Email: indiahbot@gmail.com / info@indiahbot.com
www.indiahbot.com
www.hyperbaricoxygentherapychamber.com
Bombay, India