Hyperemesis Gravidarum is a condition characterized by persistent and severe nausea and vomiting during pregnancy. It can lead to weight loss of 5% or more of the woman's pre-pregnancy weight and the presence of ketones in the urine. Potential causes include multiple gestation, trophoblastic disease, or genetic conditions like trisomy 21. Treatment focuses on managing symptoms, avoiding triggers, dietary changes, medications like antihistamines, phenothiazines, and serotonin antagonists. Intravenous fluids and supplementation of vitamins and minerals may be needed to address nutritional deficiencies and prevent complications like Wernicke's encephalopathy. Enteral nutrition through nasojejunal feeding tubes is preferable to parent

1. Hyperemesis Gravidarum Douglas M Montgomery, MD Kaiser Permanente Riverside Medical Center

4. Differential Diagnoses Goodwin (1998), Clinical Obstetrics and Gynecology 41(3).

5. Goodwin (1998), Clinical Obstetrics and Gynecology 41(3).

8. Persistent Weight Loss/Vomiting Drug Choices

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17. APGO/UTD