The document provides guidance on how to build a "medical home" for patients with mitochondrial disease by establishing a primary care physician to coordinate care across various specialists. It emphasizes finding a "quarterback" for the healthcare team and providing that physician with resources on mitochondrial disease. The medical home model aims to improve outcomes through coordinated, patient-centered care rather than a previous fee-for-service model.
This free book helps doctors and patients to cut through medical jargon, so they can learn to talk to each other. This book will help to improve doctor-patient communication, so that patients can learn to trust their doctors. This will reduce medical errors , and make medical practise more fulfilling for doctors
How Do Front line Workers Provide the Four Cs of CBNC?
Contact with newborns, case identification, care and completion of treatment. A qualitative Study.
June 2015
This free book helps doctors and patients to cut through medical jargon, so they can learn to talk to each other. This book will help to improve doctor-patient communication, so that patients can learn to trust their doctors. This will reduce medical errors , and make medical practise more fulfilling for doctors
How Do Front line Workers Provide the Four Cs of CBNC?
Contact with newborns, case identification, care and completion of treatment. A qualitative Study.
June 2015
Realizing Pediactric Adherence in TBM and HIV Home Treatment: 2013 Internship...Kate Okrasinski
The incidence of Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) is the highest in the world in South Africa. Tuberculous Meningitis (TBM) is a severe and life altering complication of sub-pulmonary TB in children. Adherence to treatment programs for both TBM and HIV are necessary for the successful treatment and management of both diseases. However, realizing pediatric adherence remains a global challenge. The calendar adherence tool was developed to support adherence. It is a sticker calendar that intents to provide positive reinforcement for children, educational information for caregivers while also supporting daily monitoring in the home and monthly monitoring in the clinic. Currently, quantitative research is evaluating the impact the tool has on adherence, however qualitative research is needed to understand just how the tool works in practice, and how it may be used in future.
The objective of this research was to explore how the calendar adherence tool fits into the existing configuration of the TBM and HIV home care settings in the Western Cape of South Africa, and identify the capacity the tool has to support pediatric adherence in the home treatment setting.
In an exploratory and qualitative study, clinical observations and semi-structured interviews were conducted with 25 respondents throughout the TBM and HIV home treatment programs. Respondents included health policy makers (n=4), physicians (n=7), healthcare staff (n=5), patients (n=5) and caregivers (n=5) involved in TBM and HIV home treatment.
The calendar adherence tool was used very differently in the TBM and HIV care settings. Due to the rigidity of the TBM home treatment program and strict enrollment criteria, adherence was well structured. The calendar adherence tool was not found to support adherence within the home or clinic setting, yet added something fun for the children and their caregivers. However, in the HIV care setting high patient volumes and universal enrollment weakened the HIV clinic’s ability to address the individual care needs of each patient and caregiver. The calendar adherence tool was used differently throughout the home care setting with HIV patients while still providing positive reinforcement. In the HIV clinic however, the calendar adherence tool was used to pinpoint adherence issues, promote a positive relationship with the clinic and identify children with little or no supervision at home.
This qualitative analysis provides insight into how diversely the calendar adherence tool is currently being used in the home care setting. As well as highlights how the tool could be used as an innovative, low tech tool to help high volume pediatric clinics identify children at risk of poor adherence, and target limited resources in practical manner to support those children and families.
Behavioral Health Staff in Integrated Care Settings | The Vital Role of Colla...CHC Connecticut
NCA Clinical Workforce Development, Team-Based Care 2019 Webinar Series
Webinar broadcast on: May 06, 2019 | 3 p.m. EST
Experts in psychology, psychiatry and nursing will share ways in which they effectively utilize their roles at the top of their license to monitor and support high-risk patients. By examining these various roles, experts will address how you can effectively support integration at your health center to improve outcomes.
Behavioral Health Staff in Integrated Care SettingsCHC Connecticut
Webinar broadcast on Feb 27, 2019 - 3:00PM EST
Delivering behavioral health services as a part of an integrated team is crucial to providing comprehensive primary care services. Focusing on the vital role of behavioral health, experts will share the key elements that maximize the contributions of these team members through structured approaches to screening, the use of “warm hand offs” to ensure connection to primary care, and implementing a robust group of treatment programs to enhance access and improve outcomes. This session will also discuss the day-to-day operation of a behavioral health program and detail the data and clinical dashboard that supports the work of these vital team members. There has been tremendous progress from health centers across the country in the integrating behavioral health, this webinar will share how integrated behavioral health can advance the team’s capability to provide effective and high quality care to complex patient populations.
IN THIS PRESENTATION I HAVE DESCRIBED ABOUT DOCTORS AND PATIENTS RELATIONSHIP . History of doctor-patient relationship. Models of doctor-patient relationship. Psychological types of doctors. Basic characters and skills of physician. Communication of doctors. Problems of contemporary healthcare system
Better Healthcare Through Community and Stakeholder Engagement, 2015 Webinar ...Paul Gallant
"An enjoyable presentation, well-delivered with excellent insight into community and stakeholder engagement strategies. Terry Dyni - July 23, 2015" on the webinar version. This version is my complete slide deck from a live webinar presentation requested by the Conference Board of Canada. April, 2015. Thanks for your interest in Better Healthcare Through Community and Stakeholder Engagement.
Compliments of Paul W. Gallant, CHE, GALLANT HEALTHWORKS & Associates (GHWA), Vancouver, BC, Canada. PS See the last slide for contact details or to arrange customized training/facilitation or advice on your organizational needs.
Communication of prognosis has multiple barriers to achieve shared understanding between patient and clinician. In this slide deck designed for Hospice and Palliative Medicine fellows, I look at some key studies and applied techniques to best address talking about 'How long do I have, doc?'
This slide deck does not cover how to formulate a prognosis.
Beyond Checklists: Care Planning for Children with Special Health Care Needs ...LucilePackardFoundation
What does it take to create and implement an effective, family-centered plan of care for a child with special health care needs? In this webinar, two expert speakers discussed their approaches to the process of care planning in two very different settings—Children's Hospital of Philadelphia and a small private practice in Vermont.
Achieving Rapid Cost Reduction and Revenue Improvement by Engaging Clinicians...PYA, P.C.
PYA Principal Kent Bottles, MD, gave the keynote address, “Achieving Rapid Cost Reduction & Revenue Improvement by Engaging Clinicians & Administrators,” at the recent Healthcare Financial Management Association’s (HFMA) 2014 Fall Institute in Bloomington, Indiana. In the presentation, he talked about how to engage physicians in all of the efforts needed to respond to the Affordable Care Act and healthcare payment reform.
Presented at Kansas City University of Osteopathic Medicine 10/27/15 in Lecture Series in Bioethics. See live presentation here: https://www.youtube.com/watch?v=Dr3g3PeVKeo
Design Thinking as innovation tool for Smart Nation: Cancer healthcareShah Widjaja
Presentation done as part of Singapore Design Week Festival 2017
Summary:
How does design thinking change mindsets and culture so that a nation like Singapore can continue to innovate and lead the transformation for a better future? Harnessing the power of design thinking to build a ‘Smart Nation’ for Singapore, this workshop aims to give audiences the opportunity to realize the potential this methodology has.
A user-centered way of solving problems, design thinking involves collaboration across user segments, through strategies like customer journey mapping, design research and rapid prototyping. While design is often used to describe an end-product, in reality if applied properly, can be used to address problems or issues across a variety of field including social issues.
Measuring Family Experience of Care Integration to Improve Care Delivery LucilePackardFoundation
The family perception of care integration is essential in identifying opportunities to improve processes of care coordination and care management. This June 15 webinar introduced the Pediatric Integrated Care Survey (PICS), a validated instrument developed by Richard Antonelli, MD, MS, Medical Director of Integrated Care at Boston Children's Hospital, and his team. The instrument assesses family experience of care integration. It asks family respondents to identify the members of their child's/youth's care team and report on their experiences with integration across disciplines, institutions, and communities.
Realizing Pediactric Adherence in TBM and HIV Home Treatment: 2013 Internship...Kate Okrasinski
The incidence of Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) is the highest in the world in South Africa. Tuberculous Meningitis (TBM) is a severe and life altering complication of sub-pulmonary TB in children. Adherence to treatment programs for both TBM and HIV are necessary for the successful treatment and management of both diseases. However, realizing pediatric adherence remains a global challenge. The calendar adherence tool was developed to support adherence. It is a sticker calendar that intents to provide positive reinforcement for children, educational information for caregivers while also supporting daily monitoring in the home and monthly monitoring in the clinic. Currently, quantitative research is evaluating the impact the tool has on adherence, however qualitative research is needed to understand just how the tool works in practice, and how it may be used in future.
The objective of this research was to explore how the calendar adherence tool fits into the existing configuration of the TBM and HIV home care settings in the Western Cape of South Africa, and identify the capacity the tool has to support pediatric adherence in the home treatment setting.
In an exploratory and qualitative study, clinical observations and semi-structured interviews were conducted with 25 respondents throughout the TBM and HIV home treatment programs. Respondents included health policy makers (n=4), physicians (n=7), healthcare staff (n=5), patients (n=5) and caregivers (n=5) involved in TBM and HIV home treatment.
The calendar adherence tool was used very differently in the TBM and HIV care settings. Due to the rigidity of the TBM home treatment program and strict enrollment criteria, adherence was well structured. The calendar adherence tool was not found to support adherence within the home or clinic setting, yet added something fun for the children and their caregivers. However, in the HIV care setting high patient volumes and universal enrollment weakened the HIV clinic’s ability to address the individual care needs of each patient and caregiver. The calendar adherence tool was used differently throughout the home care setting with HIV patients while still providing positive reinforcement. In the HIV clinic however, the calendar adherence tool was used to pinpoint adherence issues, promote a positive relationship with the clinic and identify children with little or no supervision at home.
This qualitative analysis provides insight into how diversely the calendar adherence tool is currently being used in the home care setting. As well as highlights how the tool could be used as an innovative, low tech tool to help high volume pediatric clinics identify children at risk of poor adherence, and target limited resources in practical manner to support those children and families.
Behavioral Health Staff in Integrated Care Settings | The Vital Role of Colla...CHC Connecticut
NCA Clinical Workforce Development, Team-Based Care 2019 Webinar Series
Webinar broadcast on: May 06, 2019 | 3 p.m. EST
Experts in psychology, psychiatry and nursing will share ways in which they effectively utilize their roles at the top of their license to monitor and support high-risk patients. By examining these various roles, experts will address how you can effectively support integration at your health center to improve outcomes.
Behavioral Health Staff in Integrated Care SettingsCHC Connecticut
Webinar broadcast on Feb 27, 2019 - 3:00PM EST
Delivering behavioral health services as a part of an integrated team is crucial to providing comprehensive primary care services. Focusing on the vital role of behavioral health, experts will share the key elements that maximize the contributions of these team members through structured approaches to screening, the use of “warm hand offs” to ensure connection to primary care, and implementing a robust group of treatment programs to enhance access and improve outcomes. This session will also discuss the day-to-day operation of a behavioral health program and detail the data and clinical dashboard that supports the work of these vital team members. There has been tremendous progress from health centers across the country in the integrating behavioral health, this webinar will share how integrated behavioral health can advance the team’s capability to provide effective and high quality care to complex patient populations.
IN THIS PRESENTATION I HAVE DESCRIBED ABOUT DOCTORS AND PATIENTS RELATIONSHIP . History of doctor-patient relationship. Models of doctor-patient relationship. Psychological types of doctors. Basic characters and skills of physician. Communication of doctors. Problems of contemporary healthcare system
Better Healthcare Through Community and Stakeholder Engagement, 2015 Webinar ...Paul Gallant
"An enjoyable presentation, well-delivered with excellent insight into community and stakeholder engagement strategies. Terry Dyni - July 23, 2015" on the webinar version. This version is my complete slide deck from a live webinar presentation requested by the Conference Board of Canada. April, 2015. Thanks for your interest in Better Healthcare Through Community and Stakeholder Engagement.
Compliments of Paul W. Gallant, CHE, GALLANT HEALTHWORKS & Associates (GHWA), Vancouver, BC, Canada. PS See the last slide for contact details or to arrange customized training/facilitation or advice on your organizational needs.
Communication of prognosis has multiple barriers to achieve shared understanding between patient and clinician. In this slide deck designed for Hospice and Palliative Medicine fellows, I look at some key studies and applied techniques to best address talking about 'How long do I have, doc?'
This slide deck does not cover how to formulate a prognosis.
Beyond Checklists: Care Planning for Children with Special Health Care Needs ...LucilePackardFoundation
What does it take to create and implement an effective, family-centered plan of care for a child with special health care needs? In this webinar, two expert speakers discussed their approaches to the process of care planning in two very different settings—Children's Hospital of Philadelphia and a small private practice in Vermont.
Achieving Rapid Cost Reduction and Revenue Improvement by Engaging Clinicians...PYA, P.C.
PYA Principal Kent Bottles, MD, gave the keynote address, “Achieving Rapid Cost Reduction & Revenue Improvement by Engaging Clinicians & Administrators,” at the recent Healthcare Financial Management Association’s (HFMA) 2014 Fall Institute in Bloomington, Indiana. In the presentation, he talked about how to engage physicians in all of the efforts needed to respond to the Affordable Care Act and healthcare payment reform.
Presented at Kansas City University of Osteopathic Medicine 10/27/15 in Lecture Series in Bioethics. See live presentation here: https://www.youtube.com/watch?v=Dr3g3PeVKeo
Design Thinking as innovation tool for Smart Nation: Cancer healthcareShah Widjaja
Presentation done as part of Singapore Design Week Festival 2017
Summary:
How does design thinking change mindsets and culture so that a nation like Singapore can continue to innovate and lead the transformation for a better future? Harnessing the power of design thinking to build a ‘Smart Nation’ for Singapore, this workshop aims to give audiences the opportunity to realize the potential this methodology has.
A user-centered way of solving problems, design thinking involves collaboration across user segments, through strategies like customer journey mapping, design research and rapid prototyping. While design is often used to describe an end-product, in reality if applied properly, can be used to address problems or issues across a variety of field including social issues.
Measuring Family Experience of Care Integration to Improve Care Delivery LucilePackardFoundation
The family perception of care integration is essential in identifying opportunities to improve processes of care coordination and care management. This June 15 webinar introduced the Pediatric Integrated Care Survey (PICS), a validated instrument developed by Richard Antonelli, MD, MS, Medical Director of Integrated Care at Boston Children's Hospital, and his team. The instrument assesses family experience of care integration. It asks family respondents to identify the members of their child's/youth's care team and report on their experiences with integration across disciplines, institutions, and communities.
Microsoft Exchange Server, being one of the most important production systems in many organizations is a system consisting of many moving parts that need thorough and secure maintenance. In most companies groups of two or significantly more IT professionals manage the Exchange organization configuration and without detailed auditing of who did what, where, and when it is impossible to detect inadvertent, unauthorized or sometimes accidental changes done by mistake. The white paper describes different approaches to regular and consistent auditing of changes to Exchange server configuration and permissions.
Data housed in an organization's servers and storage devices contain massive amounts of information. Much of this information is sensitive and is not intended for all eyes. It is absolutely critical that at any point in time, the organization can provide an audit trail of who accessed what, when, and where this activity took place. This white paper explains why file auditing is important and describes required file auditing features.
Mark James, VP Economic and Business Development gave this presentation to a group of business and economic development professionals in Athens, Ohio on April 24, 2013. Mark was invited by the Voinovich School within Ohio University.
IHPL presents Maharajas Express, World's Leading Luxury Train in a Special Departure on 23rd of September 2015 across the famed Golden Triangle Tour in India.
How can front-line professionals incorporate the emerging brain health ...SharpBrains
(Session held at the 2014 SharpBrains Virtual Summit; October 28-30th, 2014)
12:30-2pm. How can front-line professionals incorporate the emerging brain health toolkit to their practices?
- Elizabeth Frates, Director of Medical Student Education at the Institute of Lifestyle Medicine
- Dr. Catherine Madison, Director of the Ray Dolby Brain Health Center at California Pacific Medical Center
- Barbara Van Amburg, Chief Nursing Officer at Kaiser Permanente Redwood City
- Dr. Wendy Law, Clinical Neuropsychologist at Walter Reed National Military Medical Center
- Chair: Dr. Michael O’Donnell, Editor-In-Chief of the American Journal of Health Promotion
Learn more here:
http://sharpbrains.com/summit-2014/agenda/
Advancing Team-Based Care: Achieving Full Integration of Behavioral Health an...CHC Connecticut
This webinar highlighted ways to fully integrate behavioral health care into primary care. The role of nurses, medical assistants, behaviorists, lay health workers, and primary care providers was discussed along with the use of clinical dashboards and warm hand-offs.
This webinar was presented May 19, 2016 3:00 p.m. Eastern Time
Personal Health Budgets and Continuing HealthcareMS Trust
This presentation by Gill Ruecroft, Commissioning Manager, provides an overview of Personal Health Budgets (PHBs) and demonstrates the effectiveness of PHBs through case studies.
It was presented at the MS Trust Annual Conference in November 2014.
As new payment models emerge that emphasize value over volume, providers are being compelled to look more closely at how to motivate patients—especially those with multiple chronic conditions—to actively manage their care, make better decisions and change behaviors. This editorial webinar will explore the relationships between engagement and improved health outcomes, greater patient satisfaction and better resource utilization. Our panel of experts will share proven strategies for building patients' confidence, disseminating self-management tools and making the best use of your care team.
iHV regional conf: Theresa bishop - Strengthening Health Visiting into the fu...Julie Cooper
Presentation by Theresa Bishop at the Institute of Health Visiting Regional Professional Conferences 2015.
Theresa Bishop is Professional Lead for Health Visiting for Warwickshire.
Self advocacy is about taking a proactive approach to all stages of health and illness: prevention, diagnosis, treatment, and recovery. When people take an active role in their care, research shows they fare better both in satisfaction and in how well treatments work. In this talk you will learn how to develop the skills to be a good self-advocate, communicate effectively with your doctors, evaluate the latest health news headlines and find the best health information online.
iHV regional conf: Theresa Bishop - Strengthening Health Visiting into the fu...Julie Cooper
Presentation by Theresa Bishop at the Institute of Health Visiting Regional Professional Conferences 2015.
Theresa Bishop is Professional Lead for Health Visiting in Warwickshire.
Advancing Team-Based Care: Complex Care Management in Primary CareCHC Connecticut
This webinar investigated the ways that team members can contribute to the care of patients with complex medical and/or social needs. The focus was on developing the expanded care team and ensuring ready communication between the core and expanded care teams. Models for effective care management were presented.
This webinar was presented May 5, 2016 3:00 p.m. Eastern Time
Similar to How to Build Your Mitochondrial Medical Home (20)
-What are Standards of Care and why does the Mito community need such standards?
-Review the MMS's Standards of Care for Mitochondrial Disease and how they were developed.
-Outline upcoming MMS projects.
What you should know about genetic testing for mitochondrial disordersmitoaction
Amanda Balog, CGC, Senior Genetic Counselor, Mitochondrial and Metabolic Genetics, of GeneDx discusses: "What You Should Know About Genetic Testing for Mitochondrial Disorders."
Richard Frye, MD, PhD, FAAP, FAAN, CPI, will discuss:
*The enteric (gut) microbiome has an important influence on health and disease states in humans.
* The enteric microbiome influences the human host using chemical mediators, some of which can directly affect mitochondrial function
* Short chain fatty acids produced by gut bacteria not only modulate mitochondrial function and cellular regulatory pathways, but can also be used as mitochondrial fuels.
Exercise and nutrition in Mitochondrial Diseasemitoaction
Mark Tarnopolsky, MD, PhD, FRCP,
Depts. of Pediatrics (Neuromuscular + Neurometabolic Disease) and Medicine (Cell Biology/Metabolism, Neurology and Rehabilitation), McMaster University, Hamilton, CANADA
Diagnostic Testing for Mitochondrial Diseasemitoaction
Review traditional diagnostic pathways
Discuss newer testing that has become available in recent years
Review new approaches to attempt to shorten time to diagnosis and increase precision
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
2. I WAS ONCE ALL NEWTO THIS…
• In the beginning I was LOST.
• I had a miserable baby GIRL. I had a strong mother’s instinct that something wasWRONG.
And within the first few years, we had over 20 medical professionals from pediatricians to
occupational therapists, from neurologists to nutritionists involved, who had NO answers.
• Going from appointment to appointment trying to make sense of it all was exhausting and
overwhelming.
• Medical Record Misery
• Who is the Quarterback of this team?
3. SINCETHEN I HAVE LEARNED A LOT
AND CONTINUE TO LEARN DAILY!
• Bachelors degree in Chemistry Penn State University
• Masters degree in Chemistry UCLA
• ConsumerTaskforce, Baby’s FirstTest, Newborn Screening Education
• Member of MitoAction’s Advocacy Task Force
• Mountain States Regional Genetics Collaborative, Social Media Coordinator
• Former ParentAdvisor for Pennsylvania AmericanAcademy of Pediatrics Medical Home
Initiative
• Author,writer,blogger (www.babyfoodsteps.com) and above allAdvocate
• Patient Advocate with Empowered Medical Advocacy: EmpoweredAdvocacy.com
4. DISCLAIMER
• The medical information in this presentation is provided as an information resource only,
and is not to be used or relied on as medical advice, or for any diagnostic or treatment
purposes.
• I am not a doctor and therefore will not be able to answer questions specific to medical
treatment or diagnosis.
5. WHAT IS A MEDICAL HOME?
• When I first heard the term…
• Per the National Center for Medical Home Implementation:
• Also known as Patient Centered Medical Home (PCMH), Health Home,
A medical home is not a building or a place.
It is an approach to providing comprehensive primary care that facilitates partnerships
between patients,clinicians,medical staff,and families.
6. WHAT DOES PATIENT CENTERED MEAN?
• Patient centeredness refers to health care that establishes a partnership among
practitioners,patients,and their families (when appropriate) to ensure that decisions
respect patients’ wants,needs,and preferences and that patients have the education and
support they require to make decisions and participate in their own care.
• Institute of Medicine Envisioning a National Healthcare Quality Report (2001)
8. WHY MEDICAL HOME?
• In the past the “fee for service” model has been in place, but this model rewardsQUANTITY
not QUALITY of care.
• Providers get paid regardless of clinical outcome, with no differentiation between effective and
ineffective encounters.
• Healthcare spending is on the rise.
• There is a move from a model of productivity (more patients) to a model focused on
improved outcomes (health).
• Section 2703 of the Affordable Care Act (ACA) provided for the care of chronically ill
patients though“Health Homes”.
10. “JOINT PRINCIPLES” OF THE PATIENT-CENTERED
MEDICAL HOME MARCH 2007
• AmericanAcademy of Family Physicians (AAFP)
• AmericanAcademy of Pediatrics (AAP)
• American College of Physicians (ACP)
• American Osteopathic Association (AOA)
11. WHAT ARE THE JOINT PRINCIPLES?
• Personal physician
• Physician directed medical practice
• Whole person orientation
• Care is coordinated and/or integrated
• Quality and safety
• Enhanced access
• Payment
12. IN 2007…JOINT PRICIPLES
• “This model is an aspiration that is not currently found in most clinical practices and is
unavailable to most people in the US. This important evolution of care will require active
demonstrations,change facilitation,and a business plan that can either survive in the
current payment environment or that is specifically financed.”
• Robert Graham Center 2007 report on Patient Centered Medical Home
13. ALMOST 10YEARS LATER… WHERE ARE WE NOW?
• Still Implementing!
• Medical Homes are being set-up across the nation but is still a process and does not
happen overnight.
• For the pediatric population, evidence shows an association between access and
utilization of a medical home to the following:
• Decreased hospitalizations,including days spent at the hospital
• Decreased visits to the emergency department
• Less out-of-pocket spending from families,particularly those with public insurance
Source: https://medicalhomeinfo.aap.org/overview/Pages/Evidence.aspx
14. MEDICAL HOME ACCREDITATIONS
• Medical Home accreditation often is required to obtain an increase in reimbursement from a
health plan.
• These Accreditations may or may not impact you directly as a patient
• searchable databases available
• National Committee for Quality Assurance (NCQA):Patient-Centered Medical Home
• Joint Commission : Primary Care Medical Home
• Accreditation Association for Ambulatory Health Care (AAAHC):Medical Home On-site Certification
• Utilization Review Accreditation Commission (URAC): Patient Centered Health Care Home
• Some programs have been criticized for being too administratively focused,“check the box”,and not
focusing on bigger picture:the patient.
15. CHILDREN WITH SPECIAL HEALTH CARE NEEDS
(CSHCN) OR (CYSHCN)
• The Maternal and Child Health Bureau definition: children birth to age 21 who have or are
at increased risk for a chronic physical,developmental,behavioral,or emotional condition
and who also require health and related services of a type or amount beyond that required
by children generally.
• CSHCN: DOES NOT ONLY encompass those children who have complex disorders or
who require technology;children who have attention-deficit/hyperactivity disorder,
diabetes,emotional disorders,and autismALSO can be INCLUDED in CSHCN definition.
• CSHCN are estimated to comprise 13% of the pediatric population and account for 70%
of pediatric health-care expenditures.
16. CSHCN MEDICAL HOME, EXAMPLES
• Dr. ReneeTurchi : The Center for Children andYouth with Special Health Care
Needs,St. Christopher’s Hospital for Children:Philadelphia PA.
• Dr. Daniel Felten and Dr. Karen Fratantoni:Complex Care Program,Children’s
National Health System: Washington DC.
• Dr. EbonyWilliams: CHOSEN Clinic, UT Physicians : Houston,TX.
• More examples: https://medicalhomeinfo.aap.org/practices/Pages/Promising-Practices-
Archives.aspx
**These are just examples of various programs across the country,but do not constitute specific recommendations for care.
17. WHAT DOES THIS MEAN FOR ME OR MY CHILD
WITH MITO?
• Healthcare is in a “transition” phase
• There are medical homes that DO exist all over the country:Organic and
Accredited
• BUT one of those may not be in your town or nearby
• If you do not have a medical home currently,you may have to “build” your
own!
18. HOW TO BUILDYOUR OWN MEDICAL HOME…
• Start with the PRIMARY piece… the FOUNDATION of your Medical Home
• The “Quarterback” of your medical team
• MD= Medical Doctor
• DO= Doctor of Osteopathy (DOs receive special training in the musculoskeletal system, your body’s interconnected system of
nerves,muscles and bones.)
• Family Physcian
• Pediatrician/Developmental Pediatrician
• Internal Medicine
• General Practitioner
• Geriatrician (65 and older)
• Med/Peds (Dually trained in Internal Medicine & Pediatrics)
• Functional Medicine/Integrative Doctor
19. WHERE TO FIND A QUARTERBACK?
• Word of mouth referrals
• Asking others in the medical profession,especially nurses,therapists and specialist’s staff
• Asking others who have complex conditions or chronic conditions in your community who
their Primary Physician is and what their experience has been.
• Message Boards (buyer beware,one patient may have a great experience,another may have a
horrible experience with the same practitioner)
• Community educational events, what doctors are speaking in your town,local library,
parenting classes, go listen to them! A great way to see what they are like before you are on
the exam table.
• New Parent/ New Patient consults 15-20 minutes free consult.
20. WHEN YOU CALL…
• Polite,Courteous J
• “I am calling to find out if Dr.Quarterback is taking new patients?”
• Yes or No
• “I was referred to her and would like to speak with her about possibly being my primary physician"
• “Does Dr.Quarterback offer any new patient consultations or an opportunity to speak with her and ask
a few questions,prior to a first appointment?“
• “If not,would it be possible to schedule an introductory appointment with Dr.Quarterback to speak
with her about my medical concerns?”
• “Do you know if Dr.Quarterback is comfortable working with patients who have multiple specialists?”
21. A FEW QUESTIONS…
• What to ask of your potential new team member…
• How does your office operate? Will I be scheduled with you each time?
• Who will I see when I/my child is SICK?
• How comfortable are you in working with complex care/chronic care conditions?
• Have you ever heard of mitochondrial disease? (not a deal breaker!)
• Most importantly...Are you willing to LEARN along side me, about MITO?
• What is your philosophy on being a primary care physcian/pediatrician?
• What role do you feel the patient/or parent of patient plays on the care team?
• How do you facilitate communication with other members of a care team, both within and outside of your
office?
• What hospital do you refer to?
????
22. FIRST FEW VISITS
• Consider bringing an advocate
• Be Prepared to share your health history concisely.
• Have medical records available but do not bombard them.
• Set Reasonable Expectations for appointment length (8-15 minutes),unless you ask for more time
when you scheduled the appointment.
• Write downALL your questions but prioritize the top 3-5 that you would like answered
• Discuss situations before they become emergencies..
• What do I do if, Who do I call?
• Child has been vomitting for 24 hours?
• Child has not eaten for a day?
• Muscle weakness has lasted for a week and no improvements?
• Ask about communication methods and what you should expect if you would like to contact your
doctor: Email,Patient Portal,Phone Calls:Nursing staff vs. Doctor directly.
23. MITO RESOURCES FORYOUR DOCTOR
• Mitoaction’s A CLINICIAN'S GUIDE TO THE MANAGEMENT OF
MITOCHONDRIAL DISEASE: A Manual for Primary Care Providers
• http://www.mitoaction.org/guide/table-contents
• Mitoaction’s Podcast- 114 podcasts on many topics
• https://itunes.apple.com/podcast/audio-podcast/id290467730
• Cristy Balcells’s Book- LivingWell with Mitochondrial Disease
• available on Amazon
• UMDF’s Annual Symposium archive of talks
• https://vimeo.com/umdf
24. SICKVISITS
• Very important to see your medical home provider in good times and bad
• They need to see you/your child at your baseline to know when you are not at your baseline
• If you are having a difficult time deciding if you need to seek more urgent care-
• call your medical home FIRST, ask to be seen if the situation allows.
• Primary Care doctors can CALL AHEAD to the ER to let them know you are on your way
and help advocate for your emergency care.
• Emergency Protocol Letters- have this discussion with your doctor before an Emergency!
Mitochondrial Specialist are usually the ones to write these letters, but be sure your Medical
Home has a copy and that you have discussed it with them and how they can help.
25. ONGOING COMMUNICATION
• Sign ALL Medical Releases at ALL specialists for clinic notes to be shared with your medical
home and a copy provided toYOU the PATIENT.
• Call ahead before your appointment and ask if all the clinic notes have been received from
ALL other providers you have seen since your last appointment.
• When you see your Medical Home provider tell them who you have seen since your last visit
and ensure they have the summary clinic notes from those providers.
• If not,provide them with your copy that can be scanned into your file.
• If they did not have copies, bring this up as a concern and ask how you can work together to
make sure they are getting these communications in the future so that your care is complete.
26. CONSIDER AN ADVOCATE
• An advocate can be anyone from a friend or relative or a paid professional
advocate.
• Professional Advocates can be employed by a doctor’s office, hospital,
health insurance company,or by the patient themselves.
• A private, independent patient advocate who is hired by a patient or
patient’s family can assist in navigating medical care for their loved one.
• Advocates can help you locate options for “draft pick” Quarterbacks (and
other members of your team) and communicate with them effectively.
• ADVOConnection- Advocate directory:www.advoconnection.com
27. GETTING INVOLVED IN MEDICAL HOME INITIATIVES
• Start locally. After you establish a primary practice,ask if they have any advisory boards
or ways for patients to get involved with the practice.
• National Initiatives and opportunities for consumers/patients through the Regional
Genetics Collaboratives.
• http://www.nccrcg.org
28. ADDITIONAL RESOURCES
• MitoAction Mito Navigator Toolkit-
• http://www.mitoaction.org/mito-navigator-toolkit-overview
• Mito411- MaryBeth Hollinger is the Mito 411 Nurse Coordinator : 1-888-MITO-
411
• AAP National Center for Medical Home Implementation www.Medicalhomeinfo.org
• Patient-Centered Primary Care Collaborative www.pcpcc.org
• Medical HomeVideo https://www.youtube.com/watch?v=cZZdVpMsL6M
• Book: Being an Empowered Patient: An Advocacy Guide by Erika Balfour,MD