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Physician & Patient
Portfolio Overview
     2012-2013


       CONFIDENTIAL
HealthBridge: Core Physician Networks

       Our robust platform of Physician Networks provide
      unparalleled reach and proven targeted engagement


                            Primary
              Cardiology     Care          Diabetes



     Infectious
                                                      Oncology
      Disease


                  Surgery                    ER
                            Hospital


                            CONFIDENTIAL
Physician Networks: Multi-Channel Solutions

   Each Physician Network provides a range of proven solutions
      designed to surround and engage your target audience


                  Your Ad Here




                             Specialty                      Direct Mail
                            eNewsletters                   Monographs


                  Spotlight                 Your                   Hospital &
                  Custom                                            Practice
                   Posters                  Brand                  Wallboards             Your Ad Here

                                                                                             Your Ad Here
                                  Custom                   Physician
                                 QR Codes                   website


                                                                          advertisement




                                                                          Your
                                                                           Ad
                                                                          Here




                                            CONFIDENTIAL
Hospital Wallboards: 2,600 Locations

Engage your target audience in our 1,575 hospital network of highly
visible, engaging, single sponsored wallboard poster editions
     Hospital                Hospital                        Hospital                  Hospital
  General Edition         Surgery Edition               Cardiology Edition            ER Edition




    Your Ad Here            Your Ad Here                     Your Ad Here            Your Ad Here


 Physician Lounges        Surgeon Lounges               Cath-Labs/Lounges        ER Physician Lounges
    1,460 locations           610 locations                  330 locations             200 locations
   Weekly frequency       Bi-Monthly frequency           Bi-monthly frequency      Bi-Monthly frequency
    Includes frame           Includes frame                 Includes frame            Includes frame
  and literature pocket   and literature pocket          and literature pocket     and literature pocket



                                              CONFIDENTIAL
Hospital Wallboards: Proven ROI

Client provided ROI analysis shows significant returns
Goal:
• Product awareness and pull through messaging at targeted hospitals
Approach:
• Bi-weekly flighting to target hospitals (formulary and/or rep coverage)




Analysis:
• Regression model based on actual DDD product sales, taking into account
   multiple variables (details, formulary status, etc…)
ROI Result:
• 2.3 to 1
                                 5   CONFIDENTIAL
Clinic Posters: 2,700 Locations

Engage your target audience with a monthly poster edition to our network of
1,500 ADA registered DSME clinics and 1,200 ACCC recognized oncology
clinics
           Clinic Diabetes Edition                       Clinic Oncology Edition




                 Your Ad Here                                 Your Ad Here


           Physician Break Rooms                         Physician Break Rooms
                   1,500 clinics                                1,200 clinics
                Monthly frequency                            Monthly frequency
            Pocket available on request                  Pocket available on request



                                          CONFIDENTIAL
Practice Wallboards: 4,500 Locations

Engage your target audience with a monthly poster edition to our network of
4,200 primary care practices and 310 HIV specialist practices
            Practice PCP Edition                        Practice ID Edition




                Your Ad Here                               Your Ad Here


           Physician Break Rooms                      Physician Break Rooms
                  4,200 practices                           310 practices
                Monthly frequency                         Every other month
             Includes frame & pocket                   Includes frame & pocket



                                       CONFIDENTIAL
Wallboards: Ad Impact Benchmark Studies

Studies show significant impact in key areas
Benchmarks from 27 surveys representing over 7,000 Health Care Providers
shows advertising with our wallboard network provides significant lift vs.
control.

                     • Average ad recognition lift:                                                        +43%


                       • Average product recall lift:                                               +28%


     • Average message association lift:                                                           +21%

                       • Average intent to increase
                                                                                                   +22%
                                   prescribing lift:

Source: Orion Associates: Hospital Network, Ad Impact Survey, test vs. control: Ad
Recognition, Product Recall, & Message Association = 27 surveys/7,098 respondents: Intent to
Increase Prescribing = 8 surveys/1,397 respondents                              8   CONFIDENTIAL
Wallboards: Custom Editions


Custom Spotlight Issues

Drive home your brand or topic message
with a peer to peer custom Spotlight Issue.
                                                      Your Peer to
   • Take advantage of the entire editorial           Peer Clinical
   poster real estate                                Message Here

   • Extend your reach with customized
   take-one brochures
   • Pull-through existing approved content            Your Ad or
                                                    Clinical Message
   • Utilize our relationships with renowned
                                                    Continued Here
   KOLs to develop new content




                                     CONFIDENTIAL
Wallboards: Custom Issue Benchmark Studies


Studies show significant impact with Custom Issues

Benchmarks from 19 surveys representing responses from 3,030 Health
Care Providers shows the majority find our custom Spotlight Issues to be
extremely effective at:


    • Increasing awareness of key messages                                                        53%


       • Increasing their likelihood to prescribe                                                 54%


                         • Providing relevant information                                           66%



Source: Orion Associates: Hospital Network, Media Assessment Survey, top 2 box rating (4&5):
Increased Awareness = 17 surveys/2,737 respondents, Intent to Increase Prescribing = 19
surveys/3,030 respondents, Message Relevance = 2 surveys/447 respondents        10 CONFIDENTIAL
Custom Issue Case Study: Proven Results

                                         Custom Spotlight Edition: AZOR® Media
                                         Assessment Survey Results
                                                Q1: Prior to reading the
                                                poster, were you aware of the
                                                clinical trial results of the BP-
                                                CRUSH study?

Q2: Having reviewed the information presented, are
you now more likely to consider prescribing AZOR®
for appropriate patients with hypertension who are
uncontrolled with existing monotherapy


Q3: If so, how many hypertensive patients
uncontrolled on existing monotherapy would you
now consider prescribing AZOR® to in the next six
months?


Source: Orion Associates: Hospital Network, Media Assessment
Survey, September 2011                                         11   CONFIDENTIAL
Monographs: Peer to Peer Engagement

Pull through your message with a peer to peer developed specialty
monograph direct mailed to your target audience


                                                    Trusted Resource



  Limited Sponsorship



                                                 Peer to Peer Content
  Category Exclusivity



  Targeted Distribution




                               CONFIDENTIAL
Monographs: Engagement Statistics

Original peer to peer content drives engagement

                   65%                       of clinicians found the
                                             monograph informative




                                              of clinicians found the
                    55%                       information helpful in the
                                              care & management of
                                              their patients




                   77%                       read the accompanying
                                             advertisement


1Franklin   Communication Recognized Oncology Treatment Centers Survey 2007, N=465
                                                                          CONFIDENTIAL   13
eNewsletters: Digital Surround Sound

Take advantage of our robust and diverse database of over 260,000
e-mail registrants with one of our specialty specific eNewsletters


           Trusted Resource
                                                          Custom
                                                          Content
                                   advertisement


           Single Sponsored     Your Ad Here
                                                   Dedicated Bloggers



            17% Avg Open Rate
                                                      4.5% Avg Click-Thru




                                 CONFIDENTIAL
QR Codes: Campaign Pull-Through


      Take advantage of your website assets to drive and track
      engagement of your target audience with our custom
      QR Codes


   Posters
                        Monographs            eNewsletters


                                                      advertisement



                                                 Your Ad Here




Your Ad Here




                         CONFIDENTIAL
HealthBridge: Core Patient Networks


   Our platform of Patient Networks provide targeted reach and
                       proven engagement




         Primary                       Diabetes   Infectious
                     Cardiology
          Care                                     Disease




                             CONFIDENTIAL
Wallboards/Digital TVs: Primary Care

4,800 Practice Waiting Rooms – 16,500 High Value PCPs
                      Wallboard                                               Digital TV
  Implied                                      Exclusive
endorsement                                  Harvard content                                            90 minute loop,
                                                                                                       promo every 20-30
Relevant engaging                                                             Your Ad Here
     content

                         Your
Guaranteed ad exposure    Ad
                         Here                                                                             Single sponsor
                                                                                                              ad unit
Highly visible                                Disease state
   fixture                                     brochures       Please take one with our compliments.




             4,200 Practices (15,000 HCPs)                  600 Practices (1,500 HCPs)




                                       17    CONFIDENTIAL
Wallboards: Infectious Disease

310 Practice Waiting Rooms – 950 High Value HIV
Specialists/HCPs

    A trusted resource


                                                    Disease state brochures

  Highly visible fixture




                                             Your    Single sponsor ad unit
    Guaranteed ad exposure                    Ad
                                             Here




                             18   CONFIDENTIAL
Online: Extended Reach

Patient Ed Rx Pads distributed to 5,110 Practices drive engagement in the
exam room and out of the office with our dedicated online patient website
      Patient Ed Rx Pad



                                     Custom Practice Landing Page

                                    Implied
                                  endorsement
Simple search                                                                             Robust
                Insulin Therapy
                                                                    Insulin therapy



based input                                                                               search

                                                                                                   Comprehensive website
  Practice
specific URL



                                                                                      Dynamic




                                                                                                          advertisement
                                                                                       results            Category        Your
                                                                                                          exclusive        Ad
                                                                                                                          Here
                                                                                                           ad unit



                                                19   CONFIDENTIAL
The HealthBridge Team:

 Dedicated professional support
 • Our dedicated production team are experts in navigating the ever-changing legal
 and regulatory health care environment to ensure your needs are met with the highest
 level of compliance against tight deadlines

                                 Internal Partners

      Product Recalls                                         Tight Timelines


                                         Project
                                          Team
     Co-Promotes                                                 Agency Partners



             PI/ISI Challenges                          Editorial Needs

                                    20   CONFIDENTIAL
For a consultation or customized proposal




                      Visit:
   http://www.healthbridgepoc.com/contact-us/

                      Or Call:
                  1-866-713-4522



                      21   CONFIDENTIAL

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Health Bridge 2013 Portfolio Overview

  • 1. Physician & Patient Portfolio Overview 2012-2013 CONFIDENTIAL
  • 2. HealthBridge: Core Physician Networks Our robust platform of Physician Networks provide unparalleled reach and proven targeted engagement Primary Cardiology Care Diabetes Infectious Oncology Disease Surgery ER Hospital CONFIDENTIAL
  • 3. Physician Networks: Multi-Channel Solutions Each Physician Network provides a range of proven solutions designed to surround and engage your target audience Your Ad Here Specialty Direct Mail eNewsletters Monographs Spotlight Your Hospital & Custom Practice Posters Brand Wallboards Your Ad Here Your Ad Here Custom Physician QR Codes website advertisement Your Ad Here CONFIDENTIAL
  • 4. Hospital Wallboards: 2,600 Locations Engage your target audience in our 1,575 hospital network of highly visible, engaging, single sponsored wallboard poster editions Hospital Hospital Hospital Hospital General Edition Surgery Edition Cardiology Edition ER Edition Your Ad Here Your Ad Here Your Ad Here Your Ad Here Physician Lounges Surgeon Lounges Cath-Labs/Lounges ER Physician Lounges 1,460 locations 610 locations 330 locations 200 locations Weekly frequency Bi-Monthly frequency Bi-monthly frequency Bi-Monthly frequency Includes frame Includes frame Includes frame Includes frame and literature pocket and literature pocket and literature pocket and literature pocket CONFIDENTIAL
  • 5. Hospital Wallboards: Proven ROI Client provided ROI analysis shows significant returns Goal: • Product awareness and pull through messaging at targeted hospitals Approach: • Bi-weekly flighting to target hospitals (formulary and/or rep coverage) Analysis: • Regression model based on actual DDD product sales, taking into account multiple variables (details, formulary status, etc…) ROI Result: • 2.3 to 1 5 CONFIDENTIAL
  • 6. Clinic Posters: 2,700 Locations Engage your target audience with a monthly poster edition to our network of 1,500 ADA registered DSME clinics and 1,200 ACCC recognized oncology clinics Clinic Diabetes Edition Clinic Oncology Edition Your Ad Here Your Ad Here Physician Break Rooms Physician Break Rooms 1,500 clinics 1,200 clinics Monthly frequency Monthly frequency Pocket available on request Pocket available on request CONFIDENTIAL
  • 7. Practice Wallboards: 4,500 Locations Engage your target audience with a monthly poster edition to our network of 4,200 primary care practices and 310 HIV specialist practices Practice PCP Edition Practice ID Edition Your Ad Here Your Ad Here Physician Break Rooms Physician Break Rooms 4,200 practices 310 practices Monthly frequency Every other month Includes frame & pocket Includes frame & pocket CONFIDENTIAL
  • 8. Wallboards: Ad Impact Benchmark Studies Studies show significant impact in key areas Benchmarks from 27 surveys representing over 7,000 Health Care Providers shows advertising with our wallboard network provides significant lift vs. control. • Average ad recognition lift: +43% • Average product recall lift: +28% • Average message association lift: +21% • Average intent to increase +22% prescribing lift: Source: Orion Associates: Hospital Network, Ad Impact Survey, test vs. control: Ad Recognition, Product Recall, & Message Association = 27 surveys/7,098 respondents: Intent to Increase Prescribing = 8 surveys/1,397 respondents 8 CONFIDENTIAL
  • 9. Wallboards: Custom Editions Custom Spotlight Issues Drive home your brand or topic message with a peer to peer custom Spotlight Issue. Your Peer to • Take advantage of the entire editorial Peer Clinical poster real estate Message Here • Extend your reach with customized take-one brochures • Pull-through existing approved content Your Ad or Clinical Message • Utilize our relationships with renowned Continued Here KOLs to develop new content CONFIDENTIAL
  • 10. Wallboards: Custom Issue Benchmark Studies Studies show significant impact with Custom Issues Benchmarks from 19 surveys representing responses from 3,030 Health Care Providers shows the majority find our custom Spotlight Issues to be extremely effective at: • Increasing awareness of key messages 53% • Increasing their likelihood to prescribe 54% • Providing relevant information 66% Source: Orion Associates: Hospital Network, Media Assessment Survey, top 2 box rating (4&5): Increased Awareness = 17 surveys/2,737 respondents, Intent to Increase Prescribing = 19 surveys/3,030 respondents, Message Relevance = 2 surveys/447 respondents 10 CONFIDENTIAL
  • 11. Custom Issue Case Study: Proven Results Custom Spotlight Edition: AZOR® Media Assessment Survey Results Q1: Prior to reading the poster, were you aware of the clinical trial results of the BP- CRUSH study? Q2: Having reviewed the information presented, are you now more likely to consider prescribing AZOR® for appropriate patients with hypertension who are uncontrolled with existing monotherapy Q3: If so, how many hypertensive patients uncontrolled on existing monotherapy would you now consider prescribing AZOR® to in the next six months? Source: Orion Associates: Hospital Network, Media Assessment Survey, September 2011 11 CONFIDENTIAL
  • 12. Monographs: Peer to Peer Engagement Pull through your message with a peer to peer developed specialty monograph direct mailed to your target audience Trusted Resource Limited Sponsorship Peer to Peer Content Category Exclusivity Targeted Distribution CONFIDENTIAL
  • 13. Monographs: Engagement Statistics Original peer to peer content drives engagement 65% of clinicians found the monograph informative of clinicians found the 55% information helpful in the care & management of their patients 77% read the accompanying advertisement 1Franklin Communication Recognized Oncology Treatment Centers Survey 2007, N=465 CONFIDENTIAL 13
  • 14. eNewsletters: Digital Surround Sound Take advantage of our robust and diverse database of over 260,000 e-mail registrants with one of our specialty specific eNewsletters Trusted Resource Custom Content advertisement Single Sponsored Your Ad Here Dedicated Bloggers 17% Avg Open Rate 4.5% Avg Click-Thru CONFIDENTIAL
  • 15. QR Codes: Campaign Pull-Through Take advantage of your website assets to drive and track engagement of your target audience with our custom QR Codes Posters Monographs eNewsletters advertisement Your Ad Here Your Ad Here CONFIDENTIAL
  • 16. HealthBridge: Core Patient Networks Our platform of Patient Networks provide targeted reach and proven engagement Primary Diabetes Infectious Cardiology Care Disease CONFIDENTIAL
  • 17. Wallboards/Digital TVs: Primary Care 4,800 Practice Waiting Rooms – 16,500 High Value PCPs Wallboard Digital TV Implied Exclusive endorsement Harvard content 90 minute loop, promo every 20-30 Relevant engaging Your Ad Here content Your Guaranteed ad exposure Ad Here Single sponsor ad unit Highly visible Disease state fixture brochures Please take one with our compliments. 4,200 Practices (15,000 HCPs) 600 Practices (1,500 HCPs) 17 CONFIDENTIAL
  • 18. Wallboards: Infectious Disease 310 Practice Waiting Rooms – 950 High Value HIV Specialists/HCPs A trusted resource Disease state brochures Highly visible fixture Your Single sponsor ad unit Guaranteed ad exposure Ad Here 18 CONFIDENTIAL
  • 19. Online: Extended Reach Patient Ed Rx Pads distributed to 5,110 Practices drive engagement in the exam room and out of the office with our dedicated online patient website Patient Ed Rx Pad Custom Practice Landing Page Implied endorsement Simple search Robust Insulin Therapy Insulin therapy based input search Comprehensive website Practice specific URL Dynamic advertisement results Category Your exclusive Ad Here ad unit 19 CONFIDENTIAL
  • 20. The HealthBridge Team: Dedicated professional support • Our dedicated production team are experts in navigating the ever-changing legal and regulatory health care environment to ensure your needs are met with the highest level of compliance against tight deadlines Internal Partners Product Recalls Tight Timelines Project Team Co-Promotes Agency Partners PI/ISI Challenges Editorial Needs 20 CONFIDENTIAL
  • 21. For a consultation or customized proposal Visit: http://www.healthbridgepoc.com/contact-us/ Or Call: 1-866-713-4522 21 CONFIDENTIAL