The Carter Center has been highly effective at eradicating Guinea worm disease. Through educating villages on water filtration and providing filters, pesticide, and medical assistance, cases have dropped from an estimated 3.5 million cases in 1986 to just 148 reported cases in 2018. Other organizations have failed to make similar progress against water-borne illnesses that kill millions annually. The Carter Center's integrated approach focused on prevention and community involvement provides a model for effectively addressing other global health issues.