Glaucoma is a disease of the optic nerve that can cause vision loss and blindness if not treated. It is characterized by progressive damage to the optic nerve that begins with loss of peripheral vision. Worldwide, glaucoma is the second leading cause of irreversible blindness, affecting over 3 million people in the US alone. The most common type, primary open-angle glaucoma, has no symptoms except gradual vision loss, so regular eye exams are important. There are five main types of glaucoma: open-angle, angle-closure, congenital, secondary, and normal tension glaucoma.