George King BioMedical Lupus Anticoagulant Solutions
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This document discusses recommendations for testing lupus anticoagulant and promotes the use of George King pooled normal plasma and controls. It notes that the CLSI guideline states pooled normal plasma that most closely resembles a patient's plasma is preferred for mixing tests. It then describes how George King's pooled normal plasma meets the CLSI standards of being from 30+ screened donors, having platelet count <10 x 109/L, and coagulation factor activities >80%, and that each lot is tested and documented to be negative for lupus anticoagulant. It also promotes their normal and abnormal lupus anticoagulant controls for quality control and their lupus plasma as a positive control for lupus tests.
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Mixing studies involve mixing a patient's plasma with normal plasma to distinguish factor deficiencies from inhibitors. If the APTT or PT is corrected with normal plasma, a factor deficiency is indicated. If there is no immediate correction, a strong inhibitor is present. A time-dependent inhibitor may initially correct the clotting time but prolongation will occur after incubation. Different types of abnormal or deficient plasma can identify specific missing clotting factors when used in mixing studies.
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1) Coagulation screening tests such as PT, APTT, fibrinogen and thrombin time are used to identify underlying coagulation defects, monitor anticoagulation therapy, and evaluate for disorders involving coagulation and fibrinolysis.
2) Prolonged screening test results require follow up with mixing studies and specific factor assays to determine if the cause is a factor deficiency, inhibitor, or circulating anticoagulant.
3) Lupus anticoagulant testing involves two assays based on different principles, such as a dilute Russell's viper venom time and a sensitive activated partial thromboplastin time, to diagnose the presence of antibodies against phospholipids.
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This document provides an overview of routine coagulation assays including PT, aPTT, fibrinogen, D-dimer, and mixing studies. It discusses the clinical utility and interpretation of these assays for monitoring coagulation and detecting coagulation disorders or abnormalities. Key points include that PT measures the extrinsic pathway and factors VII, X, and prothrombin, while aPTT is more sensitive to deficiencies in the intrinsic pathway and contact factors. D-dimer has high negative predictive value for ruling out VTE but low positive predictive value due to non-specific elevations. Mixing studies can help distinguish between factor deficiencies and inhibitors like lupus anticoagulant.
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Mixing studies involve mixing a patient's plasma with normal plasma to distinguish factor deficiencies from inhibitors. If the APTT or PT is corrected with normal plasma, a factor deficiency is indicated. If there is no immediate correction, a strong inhibitor is present. A time-dependent inhibitor may initially correct the clotting time but prolongation will occur after incubation. Different types of abnormal or deficient plasma can identify specific missing clotting factors when used in mixing studies.
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1) Coagulation screening tests such as PT, APTT, fibrinogen and thrombin time are used to identify underlying coagulation defects, monitor anticoagulation therapy, and evaluate for disorders involving coagulation and fibrinolysis.
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Contents :
Blood transfusion
Blood grouping
Blood components
Blood transfusion
Complications of blood transfusion
Electrolyte abnormalities
Anion gap
General features of acid base disorders
Interpretation of abg values
Metabolic acidosis
Metabolic alkalosis
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Hypernatremia
Hyponatremia
Potassium
Hyperkalemia
Hypokalemia
Magnesium
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Phosphate
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Blood transfusion
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Blood components
Blood transfusion
Complications of blood transfusion
Electrolyte abnormalities
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Interpretation of abg values
Metabolic acidosis
Metabolic alkalosis
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Phosphate
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2) Crossmatching tests the patient's serum against donor red blood cells to identify any antibodies that could cause a transfusion reaction.
3) Computerized crossmatching can detect ABO incompatibility but requires strict data entry and confirmation of patient and donor blood types to ensure accuracy.
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1. Biochemical confirmation of endocrine disease is needed before imaging tests.
2. Simultaneous measurement of trophic and target hormones can help determine the location of abnormalities.
3. Test abnormalities do not always reflect endocrine dysfunction, and some tests may be normal despite real dysfunction. Reliability depends on choice of tests, patient preparation, specimen integrity, and test quality.
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MDC Connect: Optimising ADME and PK properties: Common mistakes made and how ...
MDC Connect: Optimising ADME and PK properties: Common mistakes made and how ...Medicines Discovery Catapult
The document discusses optimizing ADME and PK properties in drug development. It addresses common mistakes such as believing that intrinsic clearance cannot be optimized or that increasing plasma protein binding will always benefit PK. It emphasizes that intrinsic clearance, uptake clearance, and renal clearance all contribute to in vivo clearance. Good quality experimental data is important for accurate prediction of human PK. Formulation strategies can improve bioavailability when absorption is limited, but not if clearance is the dominant elimination pathway. The effects of plasma protein binding on free drug exposure are also explained.Prof. heba raslan high sensitivity testing for paroxysmal nocturnal hemoglo...
This document provides information on high sensitivity testing for Paroxysmal Nocturnal Hemoglobinuria (PNH) using flow cytometry. It discusses the disease mechanism and indications for testing. Key points include:
- PNH is a rare blood disease caused by a lack of GPI-anchored proteins on the surface of blood cells due to a genetic mutation, making red blood cells vulnerable to complement-mediated lysis.
- International guidelines have been developed for optimizing PNH testing using flow cytometry to detect clones of deficient blood cells through the use of GPI-linked antibodies and analysis of granulocytes, monocytes, and red blood cells.
- Validation methods including titration of reagents
Coagulation assays
This document discusses various coagulation assays that can be used in a laboratory setting. It describes functional clot-based assays and chromogenic assays for measuring specific enzymes. It provides examples of assays used to monitor low molecular weight heparin, detect lupus anticoagulant, and evaluate thrombophilia workups. The document emphasizes that chromogenic assays are less affected by preanalytical variables and are preferable to clot-based assays for screening protein C and free protein S deficiencies.
AAPS 2015_W3081_Biomarker Screening Poster_Russell
This document summarizes a study evaluating the utility of using multiplex panels of biomarkers for screening purposes without prior knowledge of biomarkers of interest. Fifteen multiplex panels were developed containing up to ten assays each, requiring less than 1 mL of sample to measure 122 biomarkers total. Assays showed low cross-reactivity, broad dynamic ranges, and good reproducibility. The multiplex panels allowed rapid screening and stratification of patient populations to identify potential biomarker targets.
Sample bottles.
The document provides information on the various colored blood collection tubes used in laboratories, including their common tests and proper usage. It discusses the purple, pink, blue, yellow, grey, red, dark green, and light green tubes, listing their additives, most common tests, and tips for proper collection techniques. While laboratory preferences may vary, this provides guidance on matching tests to the correct anticoagulated tube.
compatabilitytesting....................
This document discusses compatibility testing, also known as pre-transfusion testing. It defines pre-transfusion testing as procedures required to select blood and components that will have acceptable survival when transfused and will not cause destruction of the recipient's red cells. The key steps are proper identification of the recipient's sample, ABO and Rh grouping, screening for irregular antibodies, cross-matching, and selecting a compatible donor. Compatibility testing is divided into pre-analytical, serological, and post-analytical phases. The serological phase includes ABO/Rh grouping, antibody screening and identification, and cross-matching to check for compatibility between the donor's cells and the recipient's serum.
Sample bottles.
This document provides information about different colored blood collection tubes and their uses. It discusses the purposes and additives of purple, pink, blue, yellow, grey, and red tubes. The purple, pink, and blue tubes contain anticoagulants and are used for hematology and coagulation tests. The yellow, grey, and red tubes are used for biochemical and other serum-based tests. It provides examples of common tests performed using each tube type and tips for proper sample collection and handling.
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
Watch the presentation of this webinar here: https://bit.ly/3b3Tbcd
Measurement of host cell proteins is vital to ensuring a biotherapy's purity and a patient's safety. Biotherapies treat diseases with products produced by living organisms, as a result, host cell components must be characterized and controlled. We'll review new methods within product characterization for detection.
Trace amounts of host cell proteins can be present after the production and purification of any biopharmaceutical. Detection of these species requires highly specific techniques to accurately quantify even low levels of contamination. Host cell protein impurities, present at PPM-levels in biotherapies, are a major immunogenicity risk because they can elicit an unpredictable immune response in patients. Their complex and diverse nature makes them challenging to detect or monitor. With acceptance criteria for host residual DNA usually set at a very low level (often =1.0 pg of DNA per mg of drug substance), effective removal techniques and sensitive methods of detection are critical.
Antibody-based techniques, like the enzyme-linked immunosorbent assay (ELISA), have been used to assess the HCP load of biotherapeutics before and after process changes. However, these techniques do not necessarily detect qualitative changes in the HCP population. In this webinar, we will discuss how mass spectrometry (MS)-based approaches coupled with ELISA methods help detect qualitative and quantitative differences in HCP populations.
In this webinar, you will learn:
• Comprehensive HCP ID and semi-quantitation
• HC agnostic process
• Creation of process specific database
• Differential clearance of specific HCPs throughout purification steps
• Monitoring of problematic species e.g. immunogenic (PLBL2), lipases and proteases
• Explanation about why 90% of BLAs filed included this HCP MS data
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
Measurement of host cell proteins is vital to ensuring a biotherapy's purity and a patient's safety. Biotherapies treat diseases with products produced by living organisms, as a result, host cell components must be characterized and controlled. We'll review new methods within product characterization for detection.
Trace amounts of host cell proteins can be present after the production and purification of any biopharmaceutical. Detection of these species requires highly specific techniques to accurately quantify even low levels of contamination. Host cell protein impurities, present at PPM-levels in biotherapies, are a major immunogenicity risk because they can elicit an unpredictable immune response in patients. Their complex and diverse nature makes them challenging to detect or monitor. With acceptance criteria for host residual DNA usually set at a very low level (often =1.0 pg of DNA per mg of drug substance), effective removal techniques and sensitive methods of detection are critical.
Antibody-based techniques, like the enzyme-linked immunosorbent assay (ELISA), have been used to assess the HCP load of biotherapeutics before and after process changes. However, these techniques do not necessarily detect qualitative changes in the HCP population. In this webinar, we will discuss how mass spectrometry (MS)-based approaches coupled with ELISA methods help detect qualitative and quantitative differences in HCP populations.
In this webinar, you will learn:
• Comprehensive HCP ID and semi-quantitation
• HC agnostic process
• Creation of process specific database
• Differential clearance of specific HCPs throughout purification steps
• Monitoring of problematic species e.g. immunogenic (PLBL2), lipases and proteases
• Explanation about why 90% of BLAs filed included this HCP MS data
A1C Presentation-10Jun19MS (1).pptx
HbA1c lecture The number of people with type 2 diabetes is likely to double during the next 20 years (1), leading to an
increased burden of cardiovascular disease (2), renal failure (2), blindness (2),
and risk of colon, breast, and other cancers
(3). Diabetes profoundly alters macronutrient metabolism; the roles of diet and especially carbohydrate type and quality are
therefore of considerable interest. Since
1970, the total availability of sugars has
increased by ;20% (4), and high-fructose
corn syrup now represents nearly 50%
of caloric sweetener use in the United
States (4,5). Increased total fructose consumption (from both sucrose and highfructose corn syrup) has been implicated
in the development of the obesity epidemic in the United States (6) and has
been singled out in diabetes guidelines
because Diabetes associations (2,7,8) have
taken a harm-reduction approach to fructose recommendations, setting an upper
threshold for intake that is based on putative adverse effects on serum lipids.
The American Diabetes Association
guidelines, however, acknowledge that
fructose produces a lower glycemic response in people with diabetes when it
replaces sucrose and starch in the diet
(7). Fructose has also been shown to improve glycemia without adversely affecting lipids when exchanged for other
carbohydrate in controlled feeding trials
in people with type 2 diabetes (9–15).
In the absence of clear guidance on the
role of fructose in glycemic control, we
conducted a systematic review and
meta-analysis of controlled feeding
trials to assess the effects of isocaloric,
oral fructose exchange for carbohydrates
on fasting glucose, fasting insulin, and
glycated blood proteins (glycated hemoglobin [HbA1c], glycated albumin,
and fructosamine) in individuals with
diabetes.
ANTIPHOSPHOLIPID_ANTIBODY.pptx
The document discusses antiphospholipid antibody syndrome (APS), also known as Hughes syndrome. It is an autoimmune disorder characterized by blood clots and pregnancy complications. The main autoantibodies associated with APS are anticardiolipin antibodies, anti-beta 2 glycoprotein I antibodies, and lupus anticoagulant. The pathophysiology involves a hypercoagulable or prothrombotic state. Diagnosis requires both clinical criteria like blood clots or pregnancy morbidity and laboratory detection of antiphospholipid antibodies. Management typically involves anticoagulation therapy like heparin. Tests to detect lupus anticoagulant and other antibodies are also summarized.
Presentation 6
ACCULAB Corporation is a manufacturer and supplier of laboratory and medical instruments based in New York. It incorporates 7 companies to offer a wide range of products at different price points to meet customer demands. ACCULAB aims to provide both high quality products and competitive prices with a vision of being a one-stop shop for all laboratory equipment needs through excellent customer service.
Functions of a clinical laboratory
Any medical trial or clinical research is incomplete without a clinical laboratory. Traditionally speaking, a clinical laboratory examines and analyses components in blood, urine and body fluids... Blood grouping & Rh typing can also be performed.
Similar to George King BioMedical Lupus Anticoagulant Solutions (20)
MDC Connects: Biomarker identification - Assessing Immune Function
MDC Connects: Biomarker identification - Assessing Immune Function
Understanding Bioanalytical Method Validation in a Regulatory Perspective
Understanding Bioanalytical Method Validation in a Regulatory Perspective
MDC Connect: Optimising ADME and PK properties: Common mistakes made and how ...
MDC Connect: Optimising ADME and PK properties: Common mistakes made and how ...
Prof. heba raslan high sensitivity testing for paroxysmal nocturnal hemoglo...
Prof. heba raslan high sensitivity testing for paroxysmal nocturnal hemoglo...
AAPS 2015_W3081_Biomarker Screening Poster_Russell
AAPS 2015_W3081_Biomarker Screening Poster_Russell
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
Breaking the Status Quo: Using Mass Spectrometry to detect Host Cell Proteins
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Multimodal analgesia.
一比一原版(UoA毕业证)昆士兰科技大学毕业证如何办理
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Michigan HealthTech Market Map 2024 with Policy Makers, Academic Innovation C...
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
Hypotension and role of physiotherapy in it
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
TEST BANK FOR Health Assessment in Nursing 7th Edition by Weber Chapters 1 - ...
TEST BANK FOR Health Assessment in Nursing 7th Edition by Weber Chapters 1 - ...rightmanforbloodline
TEST BANK FOR Health Assessment in Nursing 7th Edition by Weber Chapters 1 - 34.
TEST BANK FOR Health Assessment in Nursing 7th Edition by Weber Chapters 1 - 34.
TEST BANK FOR Health Assessment in Nursing 7th Edition by Weber Chapters 1 - 34.FACIAL NERVE
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
Know Latest Hiranandani Hospital Powai News.pdf
As Mumbai's premier kidney transplant and donation center, L H Hiranandani Hospital Powai is not just a medical facility; it's a beacon of hope where cutting-edge science meets compassionate care, transforming lives and redefining the standards of kidney health in India.
1比1制作(uofm毕业证书)美国密歇根大学毕业证学位证书原版一模一样
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【业务选择办理准则】
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二、回国进私企、外企、自己做生意的情况，这些单位是不查询毕业证真伪的，而且国内没有渠道去查询国外文凭的真假，也不需要提供真实教育部认证。鉴于此，办理一份毕业证【微信bwp0011】即可
三、进国企，银行，事业单位，考公务员等等，这些单位是必需要提供真实教育部认证的，办理教育部认证所需资料众多且烦琐，所有材料您都必须提供原件，我们凭借丰富的经验，快捷的绿色通道帮您快速整合材料，让您少走弯路。
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
【关于价格问题（保证一手价格）】
我们所定的价格是非常合理的，而且我们现在做得单子大多数都是代理和回头客户介绍的所以一般现在有新的单子 我给客户的都是第一手的代理价格，因为我想坦诚对待大家 不想跟大家在价格方面浪费时间
对于老客户或者被老客户介绍过来的朋友，我们都会适当给一些优惠。
Sexual Disorders.gender identity disorderspptx
Gender identity disorder, paraphilias , sexual dysfunction
Digital Health in India_Health Informatics Trained Manpower _DrDevTaneja_15.0...
Digital India will need a big trained army of Health Informatics educated & trained manpower in India.
Presently, generalist IT manpower does most of the work in the healthcare industry in India. Academic Health Informatics education is not readily available at school & health university level or IT education institutions in India.
We look into the evolution of health informatics and its applications in the healthcare industry.
HIMMS TIGER resources are available to assist Health Informatics education.
Indian Health universities, IT Education institutions, and the healthcare industry must proactively collaborate to start health informatics courses on a big scale. An advocacy push from various stakeholders is also needed for this goal.
Health informatics has huge employment potential and provides a big business opportunity for the healthcare industry. A big pool of trained health informatics manpower can lead to product & service innovations on a global scale in India.
Sectional dentures for microstomia patients.pptx
Microstomia, characterized by an abnormally small oral aperture, presents significant challenges in prosthodontic treatment, including limited access for examination, difficulties in impression making, and challenges with prosthesis insertion and removal. To manage these issues, customized impression techniques using sectional trays and elastomeric materials are employed. Prostheses may be designed in segments or with flexible materials to facilitate handling. Minimally invasive procedures and the use of digital technologies can enhance patient comfort. Education and training for patients on prosthesis care and maintenance are crucial for compliance. Regular follow-up and a multidisciplinary approach, involving collaboration with other specialists, ensure comprehensive care and improved quality of life for microstomia patients.
Mental Health and Physical Wellbeing.pdf
Mental Health and well-being Presentation. Exploring innovative approaches and strategies for enhancing mental well-being. Discover cutting-edge research, effective strategies, and practical methods for fostering mental well-being.
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如果你回国在学历认证方面有以下难题请联系我们我们将竭诚为你解决认证瓶颈
1所有材料真实但资料不全无法提供完全齐整的原件。【如：成绩单丶毕业证丶回国证明等材料中有遗失的。】
2获得真实的国外最终学历学位但国外本科学历就读经历存在问题或缺陷。【如：国外本科是教育部不承认的或者是联合办学项目教育部没有备案的或者外本科没有正常毕业的。】
3学分转移联合办学等情况复杂不知道怎么整理材料的。时间紧迫自己不清楚递交流程的。
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国外旧金山大学旧金山大学硕士学位证成绩单办理方法：
1客户提供办理信息：姓名生日专业学位毕业时间等（如信息不确定可以咨询顾问：我们有专业老师帮你查询旧金山大学旧金山大学硕士学位证成绩单）；
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3旧金山大学毕业证成绩单电子版做好以后发送给您确认；
4旧金山大学毕业证成绩单电子版您确认信息无误之后安排制作成品；
5旧金山大学成品做好拍照或者视频给您确认；
6快递给客户（国内顺丰国外DHLUPS等快读邮寄）。头贼脑的倒也逗人喜爱日上三竿时山娃总爱窜进自家瓜棚里跟小伙伴们坐着聊天聊着聊着便忍不住往瓜田里逡巡一番抱起一只硕大的西瓜用石刀劈开抑或用拳头砸开每人抱起一大块就啃啃得满嘴满脸猴屁股般的红艳大家一个劲地指着对方吃吃地笑瓜裂得古怪奇形怪状却丝毫不影响瓜味甜丝丝的满嘴生津遍地都是瓜横七竖八的活像掷满了一地的大石块摘走二三只爷爷是断然发现不了的即便发现爷爷也不恼反而教山娃辨认孰熟孰嫩孰甜孰淡名义上是护瓜吃
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CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdf
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
R3 Stem Cell Therapy: A New Hope for Women with Ovarian Failure
Discover the groundbreaking advancements in stem cell therapy by R3 Stem Cell, offering new hope for women with ovarian failure. This innovative treatment aims to restore ovarian function, improve fertility, and enhance overall well-being, revolutionizing reproductive health for women worldwide.
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George King BioMedical Lupus Anticoagulant Solutions
- 1. Is Lupus Anticoagulant Testing Puzzling You? We have the pieces that can help!
- 2. The newly released CLSI H60-A- Laboratory Testing for the Lupus Anticoagulant; Approved Guideline states:
- 3. “The quality of a Pooled Normal Plasma is considered by many to be paramount to a successful mixing test.”
- 4. “Frozen Pooled Normal Plasma may be preferred since it most closely resembles the plasma with which it will be mixed.”
- 5. George King Pooled Normal Plasma has no buffers or additives and is most like your patient’s plasma.
- 6. 1. Pooled Normal Plasma should be prepared from a minimum of 20 normal individuals.
- 7. George King Bio-Medical PNP consists of 30 or more carefully screened normal donors.
- 8. 2. Platelet count should be <10 x 109 / L platelets
- 9. George King Bio-Medical PNP is platelet poor (<10 x 109 / L platelets)
- 10. 3. Activities for coagulation factors should be ≥ 80%.
- 11. George King Bio-Medical PNP has activities of >80% on all coagulation factors
- 12. 4. The absence of LA in Pooled Normal Plasma should be documented.
- 13. George King Bio-Medical PNP tests negative for LA
- 14. Each lot of GK Pooled Normal Plasma includes a Certificate of Analysis that documents: • Number of donors that make up the pnp • Platelet count of <10 x 109 /L platelets • Coagulation factor activities of >80% • Negative testing for LA
- 15. The use of internal quality control (QC) is critical to ensure the appropriateness of test results. For LA tests, suitable controls will include normal and abnormal LA material.
- 16. George King has both normal and abnormal LA controls that are suitable for use with any test system
- 17. “There is added value in the use of external (non-kit supplies) QC material with all assays.”[i] [i] Favaloro EJ, Wong RC. Laboratory testing for the Antiphospholipid Syndrome: making sense of antiphospholipid antibody assays. Clin Chem Lab Med. 2011;49(3):447-461.
- 18. “Use of non-kit supplied controls offers: • monitoring of inter-batch and inter lot variation • generation of information regarding comparability with previous lots • information regarding comparability of results when changing between different commercial kits”
- 19. George King Bio-Medical LA plasma can be used as a positive control for any lupus test including the solid-phase assays for antibodies directed against cardiolipin and B2GP1.
- 21. 1.800.255.5108