The document outlines the stratigraphy and geology of an area located between the Pub and Kirthar Ranges in Karachi, describing the lithology and thickness of the exposed sedimentary rock formations that range in age from Eocene to recent, including the Kirthar, Nari, Gaj, Manchar, and Dada Formations. Key formations discussed in more detail include the Kirthar Formation composed of limestone hills, the Nari Formation divided into lower and upper members with limestone and sandstone, and the Gaj Formation with a lower member comprised of three limestone and clay units.
CLASSIFICATION OF ORE DEPOSITS
The Mixture of ore minerals are gangue minerals form an Ore deposit. The ore
deposits are generally found enclosed within the country rocks. The ore deposits
are formed in many different ways. Depending upon the process that may
operate to produce them, the ore deposits may be classified as follow:
Magmatic ore deposits.
Sublimation ore deposits.
Pegmatitic ore deposits.
Contact metasomatic ore deposits.
Hydrothermal ore deposits
Cavity filling deposits.
Replacement deposits.
Sedimentation ore deposits.
Evaporation ore deposits.
Residual and mechanical concentration deposits
Metamorphic ore deposits.
MAGMATIC ORE DEPOSITS:
The magmatic ore deposits are the magmatic products which crystallize from
magmas. The magmatic ore deposits are classified as follows:
o Early magmatic deposits
o Late magmatic deposits
Early magmatic deposits:
Early magmatic deposits are formed during the
early stage of the magmatic period. In this case the
ore minerals crystallize earlier than the rock
silicates. The Minerals of Nickel, Chromium, and
Platinum are usually found as early magmatic
deposits. The early magmatic deposits can be sub
divided into two groups:
o Dissemination deposits
o Segregation deposits
Dissemination deposits:
When magma crystallizes
conditions, a granular igneous rock is formed. In
such a rock early formed crystals of
may occur in dissemination.
Segregation deposits:
Magmatic segregation deposits are
formed as a result of gravitative
crystallization differentiation. In
case, the ore mineral which crystallize
early, get ocean-trated on a particular
part of igneous part. The ore deposits
thus formed are known as “Segregation
deposits”.
rly under seated
ore minerals
such
Late Magmatic Deposits:
The ore deposits which are formed to
called late magmatic deposits. The late magmatic deposits contain those ore
minerals which have crystallized at rather low temperature from the residual
magma. The magma which is left after crystallization of early for
is called residual magma. This magma frequently contains many ore minerals. The
late magmatic deposits include most of the magmatic deposits of iron and
titanium ores, these deposits are almost always associated with mafic igneous
rocks.
SUBLIMATION DEPOSITS:
Sublimation is a very minor process of formation of ore deposits. Sublimation
deposits contain only those minerals which have been volatilized by hear and
subsequently redeposit in the same form at low temperature and pressure. The
sublimation deposits are found associated with Volcanoes and Fumaroles. Sulfur
of this origin has been mined in Japan, Italy, and Mexico.
Texture of Ore Minerals; Importance of Studying Textures; Individual Grains Properties; Filling of voids; Texture Types; Genetically differentiated between Texture types; Secondary textures from replacement; Hypogene Texture; Supergene Texture; Primary texture formed from Melts; Primary texture of open-space deposition; Secondary textures from cooling; Secondary textures from deformation; TEXTURES OF ECONOMIC ORE DEPOSITS; Textures of Magmatic ores; Cumulus textures; Intergranular or intercumulus textures; Exsolution textures; Textures of hydrothermal ore deposits and skarns; Replacement textures; Open space filling textures; Textures characteristic of surfacial or near surface environments and processes; Criteria for identifying replacement textures; Vein and Veining have different Nature Features
STUDY OF IMPORTANT METAMORPHIC ROCKS.pdfRITISHASINGH7
Study of important metamorphic rocks-
Petrological Characteristics, Indian Stratigraphic Position, Locality, Economic Importance and Facts about -
Granulite, Charnockite,
Eclogite, migmatites, Khondalite, Gondites.
CLASSIFICATION OF ORE DEPOSITS
The Mixture of ore minerals are gangue minerals form an Ore deposit. The ore
deposits are generally found enclosed within the country rocks. The ore deposits
are formed in many different ways. Depending upon the process that may
operate to produce them, the ore deposits may be classified as follow:
Magmatic ore deposits.
Sublimation ore deposits.
Pegmatitic ore deposits.
Contact metasomatic ore deposits.
Hydrothermal ore deposits
Cavity filling deposits.
Replacement deposits.
Sedimentation ore deposits.
Evaporation ore deposits.
Residual and mechanical concentration deposits
Metamorphic ore deposits.
MAGMATIC ORE DEPOSITS:
The magmatic ore deposits are the magmatic products which crystallize from
magmas. The magmatic ore deposits are classified as follows:
o Early magmatic deposits
o Late magmatic deposits
Early magmatic deposits:
Early magmatic deposits are formed during the
early stage of the magmatic period. In this case the
ore minerals crystallize earlier than the rock
silicates. The Minerals of Nickel, Chromium, and
Platinum are usually found as early magmatic
deposits. The early magmatic deposits can be sub
divided into two groups:
o Dissemination deposits
o Segregation deposits
Dissemination deposits:
When magma crystallizes
conditions, a granular igneous rock is formed. In
such a rock early formed crystals of
may occur in dissemination.
Segregation deposits:
Magmatic segregation deposits are
formed as a result of gravitative
crystallization differentiation. In
case, the ore mineral which crystallize
early, get ocean-trated on a particular
part of igneous part. The ore deposits
thus formed are known as “Segregation
deposits”.
rly under seated
ore minerals
such
Late Magmatic Deposits:
The ore deposits which are formed to
called late magmatic deposits. The late magmatic deposits contain those ore
minerals which have crystallized at rather low temperature from the residual
magma. The magma which is left after crystallization of early for
is called residual magma. This magma frequently contains many ore minerals. The
late magmatic deposits include most of the magmatic deposits of iron and
titanium ores, these deposits are almost always associated with mafic igneous
rocks.
SUBLIMATION DEPOSITS:
Sublimation is a very minor process of formation of ore deposits. Sublimation
deposits contain only those minerals which have been volatilized by hear and
subsequently redeposit in the same form at low temperature and pressure. The
sublimation deposits are found associated with Volcanoes and Fumaroles. Sulfur
of this origin has been mined in Japan, Italy, and Mexico.
Texture of Ore Minerals; Importance of Studying Textures; Individual Grains Properties; Filling of voids; Texture Types; Genetically differentiated between Texture types; Secondary textures from replacement; Hypogene Texture; Supergene Texture; Primary texture formed from Melts; Primary texture of open-space deposition; Secondary textures from cooling; Secondary textures from deformation; TEXTURES OF ECONOMIC ORE DEPOSITS; Textures of Magmatic ores; Cumulus textures; Intergranular or intercumulus textures; Exsolution textures; Textures of hydrothermal ore deposits and skarns; Replacement textures; Open space filling textures; Textures characteristic of surfacial or near surface environments and processes; Criteria for identifying replacement textures; Vein and Veining have different Nature Features
STUDY OF IMPORTANT METAMORPHIC ROCKS.pdfRITISHASINGH7
Study of important metamorphic rocks-
Petrological Characteristics, Indian Stratigraphic Position, Locality, Economic Importance and Facts about -
Granulite, Charnockite,
Eclogite, migmatites, Khondalite, Gondites.
Petroleum system, facies analysis and sedimentology of jurassic - cretaceous ...FatimaNasirQureshi
sedimentological differences of jurassic-cretaceous rocks in Hazara and Kohat Basin including their petrochemical analysis and depositional envoirnments
INTRODUCTION
The Indus Basin of Pakistan is divided into two parts i.e.
3
Lower Indus Basin and Upper Indus Basin. The Upper Indus
Basin is further divided by Sargodha high way into two parts.
Towards the east of the Sargodha highway in Potwar Plateau
and towards the west is Kohat Plateau. The region of the
North Punjab called as Potwar Plateau is bound in the South
by Salt range and in North by MBT as shown below.
Project work on Lithological succession, Stratigraphic classification, characteristic features, and Mineral resources of Thakkhola –Mustang Garben Sediments
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
3. Introduction
Trough: Area or depression between the Hills formed by the rim of the
Tectonic Plates.
The Area under the study lies between the south Western corner of
Karachi trough between the Pub and the Kirthar Ranges.
The exposed rocks in the area are Nari and Gaj formations of Oligocene
and Miocene respectively. however Khirthar formation of Eocene is also
exposed in the north western part.
4. Formations are continuously exposed from western coast of Karachi
to northern Sindh. forming a series of asymmetrical folds and anticlines
in southwest.
Formations consists of shale, limestone and sandstones with some
weathered material from older surroundings.
5.
6. Stratigraphy and Geology of the area
The rocks exposed in the area are Sedimentry in the origin and were
laid down in shallow marine conditions. They range in age from Eocene
to recent.
Most area is occupied by the Oligocene and Miocene ages.
7. FORMATIONS:
Dada Formation : Pleistocene to recent (1.8 million years)
Manchar Formatiom: Pliocene (5.6 million years)
Gaj Formation: Miocene (23.8 million Years)
1) Lower part
a) Metan clay unit
b) Jhill limestone unit
c) Talawa limestone unit
2) Upper part
Nari Formation: Oligocene (33.7 million years)
Khirthar Formation: Eocene (54.8 million years)
8. Age of this formation is Eocene (54.8 million years)
This formation is dominantly consists of
limestone which is dark grey, golden brown, or light grey in color.
limestone is relatively weather erosion resistant unit and forms high
hills (162m) trending from north to northeast and south to southeast in
northwestern part of the area.
It is in the form of an anticline.
KHIRTHAR FORMATION
9. Age of this formation is Oligocene (33.7 million years)
NARI FORMATION
This formation
is divided into
two members.
Lower Nari
Member
Upper Nari
Member
10. comprises of limestone in lower part and sandstone
and shale in the upper part.
limestone is dark brown, hard, nodular, thin to
medium bedded, Fossiliferious and silicious.
Shale is greenish to grey, light brown, white with
flecked rust on the surface.
Lower Nari Formation
11. This formation is well exposed.
Upper Nari Formation
Comprised of four lithological units.
Pir mangho
limestone unit
Halkani
sandstone unit
Ghora laki
limestone
Orangi
sandstone unit
12. Comprised limestone which is dark brown or golden brown in color and
weathers into rusty brown or grayish brown.
Very hard thick bedded showing concoidal fracture.
Limestone is inter layered with sandstone and sandy shale.
This unit is 319m thick in pir mangho area.
Pir Mango limestone unit
13. consists of sanstone which is soft, friable,
dark grey or brown in color, medium to
coarse grained.
Sandstone is interlayered with shale which
is light green or grey.
It is 243m thick in pir mangho area.
Halkani sandstone unit
14. consists of limestone which is dark brown
or cream colored, hard, nodular to thin
bedded.
In pir mangho area it is 67m thick.
Ghora laki limestone unit
15. Consists of sandstone which is rusty
brown, pinkish, yellow grey coloured.
Soft, Friable medium to coarse grained.
Orangi sandstone unit
16. Age of this formation is miocene (23.8
million years)
Gaj formation is divided into two members.
1) Lower member.
2) Upper member.
GAJ FORMATION
17. 1) Lower member
comprises of clay in the lower part and
limestone in the upper part.
Lower member is comprised of three units.
a) Metan clay unit.
b) Jhill limestone unit.
c) Talawa limestone unit.
18. a) Metan clay unit:
consists of clay which is khaki, grey, grayish to brown in color, soft to
moderate hard and chunky.
it is 318m thick on the western limb of pir mangho anticline.
b) Jhill limestone unit:
consists of limestone which is very hard, thin
bedded, light brown to cream colored, massive and nodular.
It is 68m thick in Jhill hill.
19. c) Talawa limestone unit:
Consists of limestone which is brown to golden brown in color, hard,
thin to thick bedded.
It is 76m thick in talawa area.
20. 2) Upper member of gaj formation
consists of interbeded clays, limestones, and sandstones in variable
proportion in different areas.
clay is grey, brown, yellow, chocolate and red in color, silt, and medium
bedded.
Limestone is hard, dark brown, thin to medium bedded, nodullar and
fossiliferious.
Sandstone is grey to greenish brown, soft medium to thick bedded and
medium to coarse grained.
21. MANCHAR FORMATION
Age is Pliocene (5.3 million years)
Comprised of sandstone extending from to goth ibrahim hyderi to goth
rehri along the coast.
Sandstone is thick bedded and massive, grey and greenish grey, soft
friable, coarse grained, interconected with sandy clay.
Sandstone suggests shalow water environment.
Upper contact of manchar with dada formation is unconferrmable.
22. Age is pleistocene to recent (1.8 million years)
It is exposed along the beach from goth ibrahim hyderi to rehri and songal area.
This Formation mainly consists of gravels loosely cemented sand and silt
matrix.
Lower contact of dada formation with manchar is unconfirmable and upper
part is covered by sub recent to recent deposits such as rock fragments,
conglomerate,sand silt and clay.
DADA FORMATION
23. References
Fatima A N 1977 stratigraphy of Pakistan(
shah S.M.I) geological society of Pakistan,, memoir 12, 29-56
Kazmi A.H and Jan M.Q 1997 geology and tectonics of Pakistan.