The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Development of dentition & occlusion /certified fixed orthodontic courses by ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
1ST, 2ND AND 3RD ORDER BENDS IN STANDARD EDGEWISE APPLIANCE SYSTEM /Fixed ort...Indian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals
who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry,
Periodontics and General Dentistry.
This slide gives you ideas about functional matrix theory revisited by Melvin moss in a series of four articles which he tells the limitations of his first study and how he corrected it . this slide includes Functional matrix theory
Constrains of FMH,Functional matrix theory revisited
Articles,Reference
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Functional matrix theory /certified fixed orthodontic courses by Indian dent...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Development of dentition & occlusion /certified fixed orthodontic courses by ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
1ST, 2ND AND 3RD ORDER BENDS IN STANDARD EDGEWISE APPLIANCE SYSTEM /Fixed ort...Indian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals
who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry,
Periodontics and General Dentistry.
This slide gives you ideas about functional matrix theory revisited by Melvin moss in a series of four articles which he tells the limitations of his first study and how he corrected it . this slide includes Functional matrix theory
Constrains of FMH,Functional matrix theory revisited
Articles,Reference
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Bite registration /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Functional matrix theory /certified fixed orthodontic courses by Indian dent...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Modus operandi of functional appliances/cosmetic dentistry coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Modus operandi of functional appliances mallik /prosthodontic coursesIndian dental academy
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Functional matrix revisited /certified fixed orthodontic courses by Indian...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
You will know what a motor control is
What are the theories and clinical implications of motor control
Physiology of motor control
Latest evidence on motor control in a musculoskeletal condition
Theories of craniofacial growth in the postgenomic era123 /certified fixed or...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Opportunity for Dentists (BDS/MDS )to relocate to United kingdom -Register as a DENTAL HYGIENIST/ DENTAL THERAPIST without Board exams and after approval you can register in GDC as a DH/DT and start working as a DH/DT Immediately and get paid.
You can complete the whole process in 3-4 months.Salary range for DH/DT is around 2500-3500 Pounds per month.
Eligibility / requirements-
1. An International English Language Testing System (IELTS) certificate
at the appropriate level.(Within 2 yrs of application date )
2: A recent primary dental qualification that has been taught and examined in English..(Within 2 yrs of application date )
3: A recent pass in a language test for registration with a regulatory authority in a country where the first language is English.
If you are interested Please contact us for more details.
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
I –Aligners are made with FDA approved transparent thermoplastic materials using 3D scanning, 3D Printing and finally Trays with Pressure vacuum formers.
Dear Doctor,
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Course includes:
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--
Indian Dental Academy
Leader in continuing dental education
www.indiandentalacademy.com
skype:indiandentalacademy
+919248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Cytotoxicity of silicone materials used in maxillofacial prosthesis / dental ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
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Diagnosis and treatment planning in completely endntulous arches/dental coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
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Properties of Denture base materials /rotary endodontic coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
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Use of modified tooth forms in complete denture occlusion / dental implant...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Dentalcasting alloys/certified fixed orthodontic courses by Indian dental aca...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
2. • Growth is a general term implying an
increase in magnitude. Development is a
maturational process.It is important for us
to know and understand this biologic
process of growth &development because at
some point of time we manipulate growth
by intervening the course of the control
process of growth by giving func- appliance
& orthopedic devices. Morphogenesis- ie
growth control process tends to achieve awww.indiandentalacademy.com
3. balance between growing parts. But as
development progress balance can never
be actually achieved because itself creates
ongoing.This process starts at childhood,
to adult-hood & goes on till old age,but the
process is slowed down as age increases
www.indiandentalacademy.com
4. • Facial growth operates with two basic kinds
of growth movement-
a) remodeling
b) displacement
• The process of remodeling is placed by the
composite of soft tissue relating to each of
the bones.
• Displacement: As bone enlarges it is carried
away from other bones. This creates space
with in which bony enlargement takes place
called “Displacement” also called
translation.
www.indiandentalacademy.com
5. VARIOUS GROWTH THEORIES
THAT HAVE BEEN PROPOSED
• Genetic control theory (Bordie 1941)
• Cartilage directed growth theory (Scott 1953)
• Sutural theory
• functional matrix theory (Moss 1960)
• Servo system theory (Petrovic 1974)
www.indiandentalacademy.com
6. • Functional matrix theory(Moss 1960)
proffit
Moss says if neither bone nor cartilage
were determinant for growth of craniofacial
skeleton,the control would lie in the
adjacent soft tissues.He theorizes that
growth of the face occurs as a response to
functional needs & is mediated by the soft
tissues in which it is embedded. HE
theorizes that growth of the maxilla &
mandible occurs due to enlargement of
nasal& oral cavities
www.indiandentalacademy.com
7. • FMT (Graber & Petrovic)
Regional & local factors play a role in cranio
facial morphogenesis. It says that the
growth of bone & cartilage seems to be a
compensatory response to FM growth.the
functional matrix include muscles,
nerves,glands, teeth,blood vessels etc.
The growth of functional matrix is primary;
the growth of skeletal unit is secondary
www.indiandentalacademy.com
8. FUNCTIONAL CRANIAL
ANALYSIS
Composed of two parts
• a functional matrix
• a skeletal unit
Skeletal unit - micro skeletal unit
- macro skeletal unit
Functional matrix - periosteal matrices
- capsular matrices
www.indiandentalacademy.com
9. PERIOSTEAL MATRICES
• For eg-functional cranial component
consisting of temporalis muscle &the
coronoid process.
• Experimental removal of the temporalis
muscle results in an actual diminution of
coronoid process size &shape.
• Also hypertrophy or hyperactivity of the
temporalis muscle produced increased size
of coronoid processwww.indiandentalacademy.com
10. CAPSULAR MATRICES
Functional matrices plus skeletal units are
organized in the form of cranial capsules.
2 cranial capsules -neuro cranial capsule &
oro facial capsules .
The expansion of the neurocranial capsule
is always proportional to the increase in
neural mass
www.indiandentalacademy.com
11. ORO FACIAL MATRICES
• All functional cranial component of the
facial skull arise, grow and are maintained
with in the oro facial capsule. This capsule
surronds & protects the oro-nasopharyngeal
functioning spaces.It is the volumetric
growth of these spaces which is the primary
morphogenetic event in facial skull growth
www.indiandentalacademy.com
12. • For the demonstration of the integrated
activity of periosteal & capsular matrices in
facial growth, mandibular growth is taken
• it is a combination of the morphologic
effects of both capsular & periosteal
matrices. Capsular growth causes an
expansion of the capsule as a whole.the
enclosed macro skeletal unit is passively &
secondarily translated in space to
successively new positions.the periosteal
matrices related to these mandibular
microskeletal units also respond to this
volumetric expansion
www.indiandentalacademy.com
13. GENETIC, EPIGENETIC
&CAUSATION
• Combination of genomic &epigenetic factors is
a necessary cause of cranio facial growth
• Biologically causation is produced by
1.a set of cells & X”tra cellularsubstance{material
2 a program encoded in the genome [format
3 an immediately antecedent, epigenetic
event[efficient]
4 some consequent use {final}www.indiandentalacademy.com
14. EPIGENETIC HYPOTHESIS
• The term epigenetic is used to describe the
sum of all bio mechanics, bio electrical, bio
chemical & bio physical parameters
produced by functioning cells ,tissues,
organs &organisms
• these factors are thought to act on the
genome to regulate all developmental
process
www.indiandentalacademy.com
15. FM HYPOTHESIS -REVISITED I
• Mechano transduction is a process of cell signal
transfer
• Biologic network theory explains the net work
of bone cells & how they interact to the signals.
• There are several mechano transductive process-
mechanoelectrical & mechanochemical which
ever used,bone adaptation requires the subsequent
intercellular transmission of the transduced
signals. www.indiandentalacademy.com
16. • Mechano sensing processes enable a cell to
sense and to respond to extrinsic loadings
by using the processes of mechano
reception and of the mechano transduction.
Mechano transduction transmits the extra
cellular physical stimulus into a receptor
cell where as the mechano reception
transforms the stimulus’s energetic and/or
informational content into an intracellular
signal.
• Osseous mechano transduction
• ionic or electrical process
• mechanical processwww.indiandentalacademy.com
17. THE ROLE OF AN OSSEOUS
CONNECTED CELLULAR NETWORK -
FMH REVISITED 2
• All bone cells except osteoclasts, are
extensively inter connected by gap
junctions that form an osseous CCN
• Gap Junctions are found where the plasma
membrane of a pair of markedly
overlapping canalicular process meet.They
also connect superficial osteocytes to
periosteal & endosteal osteoblasts .
www.indiandentalacademy.com
18. • Mechano transductively activated bone cells eg
osteocytes, can intiate membrane action potentials
capable of transmission through interconnecting gap
junctions
• In net work theory the cells are arranged into
“layers”,an intial input, a final output & a more
intermediate or “hidden”layers.Each cell in any
layer may simultaneously receive several
“weighted” inputs (stimuli)
• When an intra cellular signal is generated it is
transmitted identically to all the hidden layer cells to
which each intial layer cell is connected by Gap
junction.
www.indiandentalacademy.com
19. • The similar processes of weighted signal
summation, comparison & transmission occur in the
intermediate layers until the final layer cells are
reached . The out put of these anatomically
superficial cells determines the site, rate, direction,
magnitude and duration of the specific adaptive
response; ie deposition, resorption andor
maintenance,of each cohort of osteoblast
• CCN show oscillation. Gap junctions, permitting
bidirectional flow of information, are the cytological
basis for the oscillatory behavior of CCN
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20. A skeletal CCN displays the
following attributes
• Developmentally, it is an untrained self-
organised &self-adapting and epigenetically
regulated system.
• Operationally,it is a stable, dyanamic
system that exhibits oscillatory behavior
permitting feedback
• Structurally, an osseous CCN is non
modular
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21. FMH REVISITED-3 THE GENOMIC
THESIS
• According to this theory,the whole series of
operations to be carried out, the order and site of
synthesis and their co-ordination are all written
down in the nucleic acid message
• this thesis holds that from the moment of
fertilization,the genome contains all information
necessary to regulate - 1. The intra nuclear
formation &transcription of RNA . 2.With out any
external factor regulate intracellular &intercellular
activities of cell tissues and organs & all phenotypic
features are expressed by DNAwww.indiandentalacademy.com
22. EPIGENETIC ANTI THESIS AND THE
RESOLVING SYNTHESIS
• The epigenetic anti thesis,detailing both processes &
mechanisms,integrative,seeking to clarify the causal
chain between genome and phenotype. Its goal is to
identify & describe comprehensively the series of
initiating biological processes and their related
underlying(biochemical,biophysical)responsive
mechanisms that are effective at each hierarchical
level of increasing structural &operational
complexity.
FMH Revisited 4
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24. A RESOLVING SYNTHESIS BETWEEN
GENETIC & EPIGENETIC THEORIES
• Individually both are necessary causes, but
neither are sufficient causes alone. Together
they provide both the necessary and
sufficient causes for the control of
morphogenesis.Nevertheless,epigenetic
processes and events are the immediately
proximate causes of development, and as
such they are the primary agencies.
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