1) The document assesses how existing and future hydropower development in the Sekong, Sesan and Srepok rivers of the Mekong Basin could change river flow regimes. 2) It compares the impacts of dams built in tributaries versus the mainstream Mekong on flows and water levels, and examines different scenarios of dam development and operation. 3) The results indicate that future dam development could significantly reduce seasonal flows in the Mekong River, with potential downstream impacts on areas like Tonle Sap and the Mekong Delta.