The document analyzes the combined effects of climate change and hydropower development on the flows of the Sekong, Sesan, and Srepok rivers in the Mekong basin, highlighting concerns over aquatic biodiversity and the dependence of local populations on river resources. It concludes that hydropower development has a more significant impact on river flows than climate change, which can exacerbate extreme weather events but may be managed through large storage dams. The study emphasizes the need for coordinated efforts across borders to address the resulting downstream impacts and potential conflicts.