2012 (Feb 8-10) Integrated Chronic Disease Prevention: It Works! CDPAC Fourth Pan-Canadian Conference, presentation by BRAID Research and Driftpile First Nation
Growth prospects of children after discharge from malnutrition treatment cent...POSHAN
This presentation was made by Dr. Jyoti Sharma (Public Health Foundation of India) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Addressing severe-acute malnutrition in Rajasthan using community-based strat...POSHAN
This presentation was made by Dr. Deepti Gulati (GAIN) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Factors Associated with Early Growth in Egyptian Infants KAVLECORE Group
CORE Group GHPC15
October 8, 2015
Concurrent Session: Factors Associated with Growth in the First 1,000 Days: Translating Evidence into Programs for Stunting, Wasting, and the Double Burden of Malnutrition
Growth prospects of children after discharge from malnutrition treatment cent...POSHAN
This presentation was made by Dr. Jyoti Sharma (Public Health Foundation of India) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Addressing severe-acute malnutrition in Rajasthan using community-based strat...POSHAN
This presentation was made by Dr. Deepti Gulati (GAIN) in the session on ‘Implementation research on delivery of preventive and curative interventions during early childhood’ at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Factors Associated with Early Growth in Egyptian Infants KAVLECORE Group
CORE Group GHPC15
October 8, 2015
Concurrent Session: Factors Associated with Growth in the First 1,000 Days: Translating Evidence into Programs for Stunting, Wasting, and the Double Burden of Malnutrition
A tool to assess gaps in district-level coverage of nutrition interventions i...POSHAN
This presentation was made by Dr. Sumathi Swaminathan and Mr. Jithin Sam Varghese (St. John’s Research Institute) in the session on 'Assessing coverage and performance of nutrition interventions: Research experiences from across India' at POSHAN's "Delivering for Nutrition in India - Learnings from Implementation Research" conference, November 9–10, 2016 , New Delhi.
Improving women's diet quality preconceptionally and during gestation: Effect...POSHAN
This presentation was made by Dr. Sirazul Ameen Sahariah (Centre for the Study of Social Change) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Antenatal care and counseling measures increase iron and folic acid receipt a...POSHAN
This presentation was made by Amanda Wendt (University of Heidelberg) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Impact of nutrition interventions on infant feeding and other outcomes in Utt...POSHAN
This presentation was made by Laili Irani (Population Council) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Insights from formative research from Bihar and Uttar Pradesh on maternal die...POSHAN
This presentation was made by Dr. Sebanti Ghosh (Alive & Thrive) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Effect of Peer Counselling by Mother Support Groups on Infant and Young Child...POSHAN
This presentation was made by Arun Gupta (Breastfeeding Promotion Network of India) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Kate McKay'From Anatomy To Policy: How advancing neuroscience helped shape po...BASPCAN
'From Anatomy To Policy: how advancing neuroscience helped shape policy shift in the Early Years in Scotland '
There are significant differences in child mortality between high income countries and modifiable factors continue to be identified.These include biological and psychological factors, physical environment, social environment and service delivery. There is an inverse relationship between socioeconomic status and child mortality. So to reduce child mortality ,requires tackling perinatal causes and co-ordinated strategies to reduce antenatal and perinatal risk factors are essential .We need to identify evidence based prevention strategies which start in pregnancy and continue into the first years of a baby's life to reduce harm and build resilience .We need to understand what are the barriers and facilitators of behavioural change in pregnant women and health professionals .This presentation will outline some of the neurodevelopmental and anatomical changes in the child's brain which are most affected by forms of child abuse and neglect and outline current Scottish Government policies which are delivering on prevention , to make Scotland ‘The best place to grow up ‘.
Dr Katherine McKay has been a consultant paediatrician since 1995, working in areas of high deprivation in Glasgow. Her special interests are Community Paediatrics, particularly disability, including children with complex needs and life limiting conditions, child protection and the vulnerable child, and interagency work with social work and education.
She became Lead Clinician for Community Child Health in Glasgow in 2000, and Clinical Director from 2005 till 2010 covering all of the Glasgow City CHCPs and CHPs in a period of significant organisational change towards Integrating Children's Services across health, education and social work. She has been a fellow of the Royal College of Paediatrics and Child Health since 1994, Clinical Adviser to NHS QIS on the first Standards for Children's Services published in 2004 for Children and Young People with Asthma and then was an Associate Inspector for HMIE in the Child Protection Inspections.
She was National Clinical Lead for Children and Young People's Health in Scotland from August 2010 to 2012 and then became Senior Medical Officer for Child Health in October 2012. Since October 2012 her main policy input has been in Early Years, especially the Implementation of GIRFEC, in universal health services; the identification and response to vulnerable children by health services; Child Death Review Systems; and the health service input to Looked After Children. She continues a clinical practice one day every fortnight.
Longitudinal Changes in Anthropometric Measures in Children in 5th Grade_ACSM...Brianna Higgins
Poster Presentation at 2016 ACSM Annual Meeting, analyzing the change over one year in anthropometric measures in children participating in school-based obesity intervention.
Health outcomes of Aboriginal individuals with early onset diabetesKelli Buckreus
2010 (Oct) 3rd Conference on Recent Advances in the Prevention and Treatment of Childhood and Adolescent Obesity, poster presentation by BRAID Research
A tool to assess gaps in district-level coverage of nutrition interventions i...POSHAN
This presentation was made by Dr. Sumathi Swaminathan and Mr. Jithin Sam Varghese (St. John’s Research Institute) in the session on 'Assessing coverage and performance of nutrition interventions: Research experiences from across India' at POSHAN's "Delivering for Nutrition in India - Learnings from Implementation Research" conference, November 9–10, 2016 , New Delhi.
Improving women's diet quality preconceptionally and during gestation: Effect...POSHAN
This presentation was made by Dr. Sirazul Ameen Sahariah (Centre for the Study of Social Change) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Antenatal care and counseling measures increase iron and folic acid receipt a...POSHAN
This presentation was made by Amanda Wendt (University of Heidelberg) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Impact of nutrition interventions on infant feeding and other outcomes in Utt...POSHAN
This presentation was made by Laili Irani (Population Council) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016, New Delhi.
For more information about the conference visit our website: www.poshan.ifpri.info
Insights from formative research from Bihar and Uttar Pradesh on maternal die...POSHAN
This presentation was made by Dr. Sebanti Ghosh (Alive & Thrive) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Effect of Peer Counselling by Mother Support Groups on Infant and Young Child...POSHAN
This presentation was made by Arun Gupta (Breastfeeding Promotion Network of India) in the session on 'Implementation research on delivery of interventions during pre-pregnancy through lactation' at the POSHAN Conference "Delivering for Nutrition in India Learnings from Implementation Research", November 9–10, 2016.
For more information about the conference visit our website: www.poshan.ifpri.info
Kate McKay'From Anatomy To Policy: How advancing neuroscience helped shape po...BASPCAN
'From Anatomy To Policy: how advancing neuroscience helped shape policy shift in the Early Years in Scotland '
There are significant differences in child mortality between high income countries and modifiable factors continue to be identified.These include biological and psychological factors, physical environment, social environment and service delivery. There is an inverse relationship between socioeconomic status and child mortality. So to reduce child mortality ,requires tackling perinatal causes and co-ordinated strategies to reduce antenatal and perinatal risk factors are essential .We need to identify evidence based prevention strategies which start in pregnancy and continue into the first years of a baby's life to reduce harm and build resilience .We need to understand what are the barriers and facilitators of behavioural change in pregnant women and health professionals .This presentation will outline some of the neurodevelopmental and anatomical changes in the child's brain which are most affected by forms of child abuse and neglect and outline current Scottish Government policies which are delivering on prevention , to make Scotland ‘The best place to grow up ‘.
Dr Katherine McKay has been a consultant paediatrician since 1995, working in areas of high deprivation in Glasgow. Her special interests are Community Paediatrics, particularly disability, including children with complex needs and life limiting conditions, child protection and the vulnerable child, and interagency work with social work and education.
She became Lead Clinician for Community Child Health in Glasgow in 2000, and Clinical Director from 2005 till 2010 covering all of the Glasgow City CHCPs and CHPs in a period of significant organisational change towards Integrating Children's Services across health, education and social work. She has been a fellow of the Royal College of Paediatrics and Child Health since 1994, Clinical Adviser to NHS QIS on the first Standards for Children's Services published in 2004 for Children and Young People with Asthma and then was an Associate Inspector for HMIE in the Child Protection Inspections.
She was National Clinical Lead for Children and Young People's Health in Scotland from August 2010 to 2012 and then became Senior Medical Officer for Child Health in October 2012. Since October 2012 her main policy input has been in Early Years, especially the Implementation of GIRFEC, in universal health services; the identification and response to vulnerable children by health services; Child Death Review Systems; and the health service input to Looked After Children. She continues a clinical practice one day every fortnight.
Longitudinal Changes in Anthropometric Measures in Children in 5th Grade_ACSM...Brianna Higgins
Poster Presentation at 2016 ACSM Annual Meeting, analyzing the change over one year in anthropometric measures in children participating in school-based obesity intervention.
Health outcomes of Aboriginal individuals with early onset diabetesKelli Buckreus
2010 (Oct) 3rd Conference on Recent Advances in the Prevention and Treatment of Childhood and Adolescent Obesity, poster presentation by BRAID Research
Objective: Food habits may be associated with inflammation, but there is little information about processed and ultra-processed foods in children. Thus, our aim was to investigate the relationship between processed and ultra-processed foods, energy intake, total fat and saturated fats intake and high sensitivity C - reactive protein levels (hs - CRP) in children.
Design: A cross-sectional study with a population-based cluster sample.
Speaker presentation from U.S. News Healthcare of Tomorrow leadership summit, Nov. 17-19, 2019 in Washington, DC. Find out more about this forum at www.usnewshot.com.
Speaker presentation from U.S. News Healthcare of Tomorrow leadership summit, Nov. 17-19, 2019 in Washington, DC. Find out more about this forum at www.usnewshot.com.
What are the causes and effects of childhood obesity, and what strategies can health and government bodies use to tackle the issue? Nathalie Farpour-Lambert, President of the European Association for the Study of Obesity (EASO), examines scientific data and presents recommendations. This presentation was delivered as part of a Global Active City and Ciudad Activa Summit in Buenos Aires in October 2018. EASO is a supporting partner of the Active Well-being Initiative, which runs the Global Active City programme. The world’s first Global Active Cities are Buenos Aires, Hamburg, Lillehammer, Liverpool, Ljubljana, and Richmond, British Columbia, Canada. Visit http://www.activewellbeing.org or follow @AWBInitiative on Twitter.
Globally 165 million children under-five
years of age are stunted. Hence development of local
therapeutic nutritional intervention is recommended by WHO.
Present study was designed to find the efficacy of the
nutritional intervention for the recovery of impaired lipid
metabolism and correlation of weight for height% with
cholesterol, triglyceride in malnourished children. 105 test and
100 control SAM children without infection, of 1 to 5 years of
age and either sex were enrolled. Test group was given
treatment of nutritional intervention therapy, providing 2.5 to
3gm Protein and 90-100 kcal /kg body Weight/day, for the
three months. Their Anthropometric, and Biochemical
parameters were measured before and after the nutritional
therapy. Before the nutritional intervention treatment P values
for Serum Total cholesterol, Triglyceride, Weight for height
%, were insignificant suggestive of similar baseline
characteristics at enrollment. After nutritional intervention
treatment P values for Serum Total cholesterol, Triglyceride,
Weight for height % were highly significant. The r value of
Pearson correlation coefficient for triglycerides in the study
group and its ANOVA model was very significant, showing
poor positive correlation with weight for height % while for
total cholesterol it was found to be insignificant. Depending on
results we conclude that it is the most effective food supplement
for the speedy recovery of the impaired lipid metabolism in
SAM children and the use of weight for height % as a
anthropometric marker for the pre-indication of fatty liver in
malnourished children
Aene project a medium city public students obesity studyCIRINEU COSTA
Identifying undernutrition and obesity on students and propose public policies of health are urgent issues. This paper presents a study with weight and stature from students collected by physical education teachers (PEF) in schools of a city near São Paulo. The PEF collected the data and they were inserted in a program especially developed for each school Department (AENE Project). The datas were analyzed by software and evaluation done based on a World Health Organization (WHO_2007) table, that develops health programs worldwide. The results evaluations were used to raise the students and family, teachers and responsibles for treatment search (when required).
DAILY YOGURT CONSUMPTION HELPS PREVENT HEART DISEASE - Luis Moreno (Universi...Yogurt in Nutrition #YINI
Europe-wide study shows adolescent milk and yogurt consumers have lower cardiovascular disease risk. Many adolescents are at risk of developing cardiovascular disease (CVD) as a result of being overweight, having increased blood pressure or high cholesterol. The results of a Europe-wide study suggests a cardiovascular protective effect of milk and yogurt, with girls who consumed these dairy products on a regular basis having a lower CVD risk, and both boys and girls being significantly less overweight. “Our data suggest that yogurt and milk can play a key role in fighting obesity and CVD in adolescents,” says Professor Luis A. Moreno from the University of Zaragoza in Spain, who presented the findings at the III World Congress of Public Health Nutrition in Spain.
Service providers who receive high nutrition risk referrals, particularly Registered Dietitians, need to be knowledgeable about general and clinical pediatric nutrition as well as counselling skills for working with families and children.
This is the first of five self-directed training modules available in PowerPoint presentations that have been developed and evaluated to respond to this need
Screening for diabetes and its complications as part of the Alberta Diabetes ...Kelli Buckreus
2004 (Jan) 3rd National Conference on Diabetes and Aboriginal Peoples, National Aboriginal Diabetes Association (NADA), poster presentation by BRAID Research
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Fitness improvements amongst children in one Alberta First Nation after eight years of particpatory research and Community commitment
1. Fitness Improvements among children
in one Alberta First Nation
BRAID-Kids
BRAID Prevention of Obesity and Diabetes in
Children and Families (BRAID-Kids)
Paulette Campiou, Diabetes Coordinator, Driftpile First Nation
Dr. Ellen Toth, Principal Investigator, University of Alberta
2. BRAID = Believing we can Reduce Aboriginal Incidence of Diabetes
ORIGINAL BRAID STUDY (2003-2006)
Collaboration between Driftpile and the University of Alberta.
Screened the population of Driftpile for undiagnosed diabetes (including
children)
Screening results in 89 children and adolescents:
Community wanted to work on PREVENTION, involving children and their
families
Pre-diabetes 27%
Probable diabetes 1.2%
Overweight 22%
Obese 44%
3. Setting:
DRIFTPILE CREE NATION is 350
kms northwest of Edmonton,
Alberta, on the shores of Lesser
Slave Lake
Driftpile has approximately 1600
Band Members, of whom about 850
live on reserve land.
Driftpile is home to approximately
200 children and adolescents ages
5-17.
4. BRAID-Kids STUDY DESIGN
BRAID-Kids was based on the Kahnawake Schools
Diabetes Prevention Program (KSDPP) and the Sandy
Lake diabetes prevention program, and used educational
materials and assessment tools developed by these
programs.
However, BRAID-Kids planned to have an improved
study design – Cree Pride – based on Pima Pride: a “de-
colonizing” project where exposure to Pima tradition and
culture improved diabetes control (Narayan, 1998)
5. BRAID-Kids & Cree Pride
BRAID
(original
study)
Pima
Action /
Pima
Pride
KSDPP
(Kahnawake) Sandy Lake
DPP
6. BRAID-Kids
Hypothesis: Decolonization may enable First Nations families to avoid
behaviors that contribute to obesity and diabetes risk.
Primary Outcome: assess physical activity and dietary choices amongst
children, by:
Measuring clinical, anthropometric and fitness outcomes of
participating children near the beginning and end of each school year;
Administering a food frequency and physical activity questionnaire
Implementing an in-classroom diabetes prevention curriculum;
Implementing a tradition-based “Cree Pride” program aimed at
parents/guardians/families.
8. RESULTS:
Recruitment: 89 children and their families were recruited, but this
took 2 years
Fitness assessments and risk assessments were conducted near
the beginning and end of the school year.
BRAID-Kids Project Dietitian visited the school and the community
regularly
The Cree Pride intervention component was developed as 6-10
sessions but it was not implemented, due to competing activities
and programs being carried out by the community, the recreation
department, the health center and school;
.
9. Baseline clinical, anthropometric for all children measured by BRAID-Kids, N=89
MEASUREMENT RESULTS
Gender, % female 42 (47.2%)
Mean age, years 8.2 (range: 4-15)
Fasting glucometer blood glucose, N=59
Mean (mmol/L) 5.4 (range: 4.3-7.8)
“Possible” diabetesa, # of children (%) 1 (1.7%)
“Possible” pre-diabetesb, # of children (%) 7 (11.9%)
Body Mass Index (BMI), N=87:
≥85th-<95th, overweightc, # of children (%) 18 (20.7%)
≥95th, obesityc, # of children (%) 43 (49.4%)
Central adiposityd, N=88, # of children (%) 74 (84.1%)
Hypertensione, N=60, # of children (%) 14 (23.3%)
a. fasting blood glucose ≥7.0 mmol/L; b. fasting blood glucose 6.1-6.9 mmol/L; c. CDC percentile reference for age and gender; d. NHANESIII: central adiposity
= waist circumference ≥85th percentile for age and gender; e. CDC percentile reference for age and gender, hypertension: ≥95th percentile;
11. Fitness percentiles for age and gender, N=86a
Gender (% female) 37 (43.0%)
Mean Age (years) 9
Fitness: percentile for age and genderb
, N = 86
# of children < 5th percentile (percent) 58 (67.4%)
# of children 5th to <10th percentile (percent) 8 (9.3%)
# of children 10th to <20th percentile (percent) 9 (10.5%)
# of children 20th to <30th percentile (percent) 5 (5.8%)
# of children 30th to <40th percentile (percent) 1 (1.2%)
# of children 40th to < 50th percentile (percent) 3 (3.5%)
# of children 50th to <60th percentile (percent) 2 (2.3%)
# of children below 20th percentilec
(percent) 75 (87.2%)
Baseline Fitness results for children who underwent fitness
testing by BRAID-Kids
a. children under the age of 6 were excluded, per Leger reference (Leger, 1984)
b. (Leger, 1984)
c. relative fitness = >20th percentile (Downs, 2006)
12. RESULTS AFTER ONE YEAR
We looked at changes for children who had repeat tests
undertaken after a 1 year interval:
Significant improvements in fitness scores (in age-and-
gender percentile rank and VO2 Max)
No differences in glucose, weight, waist or BP except for an
increase in the % of children with diastolic (but not systolic)
hypertension
*
BASELINE RESULTS
Baseline results were once again consistent with our very high
rates of overweight and obesity and very low levels of fitness
reported for some First Nations communities.
13. Mean improvements in age-and-gender percentiles for children
tested at 1 year intervals (Leger, 1984), N=19
* p < 0.01 from paired t-test
14. Mean VO2 Max values for children tested at 1 year
intervals (n = 24)
* p < 0.01 from paired t-test
15. INTERPRETATION
Observed improvements in fitness are likely not a direct result of BRAID-
Kids alone:
A new physical education program with a specific gym teacher at
the school was very helpful
Because of regular “beep tests” in gym class, children became
practiced at test procedures
Increased surveillance communicated a focus on fitness to
children and their families.
Since many Band Councils control their community’s education
budget and policies, our results may be helpful information for
Leadership decision-making.
16. IN SUMMARY
Positive things are happening:
Some families report having changed their eating
habits.
BRAID-Kids Project Dietitian visiting Driftpile regularly.
Full-time school gym teacher.
numerous community efforts at promoting prevention
and healthy living; and,
CREE PRIDE
21. Acknowledgements:
Lawson Foundation
Alberta Center for Child Family and Community Research
Chief Rose Laboucan
Health Director Florence Willier
Research assistants:
Trina Scott
Tessirae Sasakamoose
Priscilla Lalonde
U of A support: Kelli Ralph Campbell
Dietitian: Kari Quinn