Methamphetamine (meth) is a highly addictive stimulant that is prevalent among young people and men who have sex with men in the United States. It is made from toxic chemicals and often in illegal home labs. Meth use increases risky behaviors like unprotected sex and needle sharing, fueling the transmission of HIV. Users may feel invincible while high but experience severe depression and health issues after the effects wear off. Those with HIV who use meth face additional health challenges due to interactions between the drug and HIV medications. Treatment programs aim to address addiction as well as related diseases.