The heart has 3 layers, 4 chambers, and 4 valves. It is located in the thoracic cavity and pumps oxygenated blood to the organs and tissues while removing waste. The cardiovascular system includes pulmonary circulation to oxygenate blood in the lungs and systemic circulation to deliver oxygenated blood throughout the body. The heart's conduction system uses sinoatrial and atrioventricular nodes and Purkinje fibers to control the heartbeat and ensure blood flows in one direction through the cardiac cycle.