Farming system research (FSR) involves scientists working with farmers to define problems and find solutions to improve farmer benefits sustainably. The conventional technology generation and dissemination approach had disadvantages like not considering farmer needs. FSR is farmer-based, problem-solving, interdisciplinary, and interactive. It involves building knowledge of farming systems through on-farm research managed by scientists and farmers. Case studies show integrating indigenous technical knowledge from farmers improved pest management and weed control techniques. However, fully understanding complex local systems and scaling up innovations from indigenous knowledge remains challenging for FSR.