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Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
FAO’s Commitment to maintaining GlobalFAO’s Commitment to maintaining Global
Rinderpest FreedomRinderpest Freedom
Samia Metwally
Animal health officer (Virology)Animal health officer (Virology)
Animal Production and Health DivisionAnimal Production and Health Division
Rinderpest co-secretariatRinderpest co-secretariat
FAO of the United NationsFAO of the United Nations
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Content
• Global rinderpest eradication program
• Current issues
• Post-eradication to maintain freedom
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Eradication
Collaboration between all partners
Member
Countries
FAO
GREP
OIE
OIE Pathway
Validate Dossiers
Submission of
Dossiers
Assist activity
implementations
RECs
Financial support
by multiple donors
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Last outbreaks of rinderpest in Asia, Europe
and Middle East
Europe
– Italy (Roma !!) 1949
Asia
– Japan 1924
– China 1956
– Bangladesh 1958
– Vietnam 1977
– Mongolia 1992
– India 1995
– Pakistan 2000
Middle East
– Saudi Arabia 1997
– Iraq and Turkey 1996
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
2011
Declaration of Rinderpest Global Freedom
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
There is no longer room to doubt that Rinderpest
has been eradicated from the world
There is no longer room to doubt that Rinderpest
has been eradicated from the world
Rinderpest virus is
currently kept
in many laboratories in
many countries
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
2011: Priorities of Post-Eradication
1. approval of a minimum number of facilities for holding rinderpest virus and
vaccine
2. develop a rinderpest virus sequestration policy
3. destroy rinderpest-virus containing material or store it in a minimum number
of approved facilities
4. awareness raising and ensure secure handling of rinderpest virus-containing
material
5. essential research projects- approved by FAO and OIE
6. adequate surveillance systems, national preparedness and non-infectious
diagnostic tests
7. international preparedness plan
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
June 2012: Established FAO-OIE Rinderpest Joint Advisory
Committee and Rinderpest Secretariat
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Moratorium on Rinderpest Virus
o FAO/OIE press releases: ‘call for countries to comply
with moratorium on research using live virus’ (July
2012)
o FAO/OIE Press release: ‘Moratorium on using live
rinderpest virus lifted for approved research’ (July
2013)
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Established FAO-OIE rinderpest
holding facilities
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
FAO Project (USA- funded 2015-16)
Objective 1: Increased coordination of rinderpest post-
eradication activities and raising awareness
Objective 2: Increased sequestration and destruction of
rinderpest virus
Objective 3: Disease surveillance systems at national,
regional and global levels
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
- Raise public awareness for three target audiences
• Livestock holders, wildlife handlers and community leaders
• Governments (veterinary authorities and lab personnel)
• Academia
• Regional community outreach- Africa and Asia
Communication and Advocacy
Keeping Rinderpest on the Radar Screen
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Regional Community outreach
• Regional Meeting for Africa, Sharm al Sheikh, Egypt 5-6 August
– 9 countries attended plus RHFs and international organizations, AU-IBAR
– The five countries keeping the virus agreed to destroy or sequester their virus
– All countries agree to work with FAO to raise awareness for rinderpest
– Countries pledged to destroy and sequestrate the virus before 2018
– Focal points for virus destruction and raising awareness
– One country was reluctant to transfer their virus (now onboard)
– New countries reported to keep vaccine stock
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Facilitate and Encourage Virus Destruction
and Sequestration
 Facilitate virus sequestration and destruction
 Analyze questionnaire data (vaccine and wild-type virus)
 Develop Disease spread model – demonstrate the impact
 Support to countries holding rinderpest virus:
flexible support options
Expert team missions; Africa and Asia
Procurement of laboratory consumables and equipment to enable
destroying stocks
Transfer of virus to the established FAO-OIE holding facilities
 Equipment procured to support the FAO-OIE RHFs
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
FAO Support
Virus Transfer/Destruction/ Facility Decontamination
• SOPs on virus destruction, shipping, lab decontamination
• Facilitate shipping and freight cost
• Provide biosafety/biosecurity training on site
• Deploy experts team for assistance
• Provide equipment (i.e.) biosafety cabinet and/or portable
autoclave
We can assist immediately
rinderpest-secretariat@fao.org
+39 06 570 55838
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Countries destroyed or sequestered their virus
stock in 2015
– Botswana:
• Two shipments of vaccine virus seed to to Botswana to FAO-OIE RHF at
AU-PANVAC- long process 8 months to complete
– Australia:
• Destroyed their stock last month
– Sudan:
• Final arrangements to ship their stock to AU-PANVAC
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Disease surveillance systems at national,
regional and global levels
Detect and report any emergence of rinderpest
Include rinderpest in the differential diagnosis
and rule out with look alike diseases
Disease recognition
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy
Areas that need support…
• Continue virus destruction and sequestration efforts
USD160,000
• Post Rinderpest eradication outreach and education USD60,000
• International Preparedness Plan
– Funding to support a consultant on its development USD30,000
– Convene a stakeholders’ consultation on emergency funding USD50,000
– Conduct national simulation exercises in high-risk regions USD 120,000
• Vaccine production, regional vaccine banks
– Develop a policy and strategy for providing vaccine in the case of an
outbreak (type, doses, geographic locations, mechanism of activation
and delivery, etc) USD20,000
– Secure funding for vaccine stockpile USD 1 Million
• Manage and deploy a non-infectious diagnostic tool USD200,00018
Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy

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FAO’s commitment to maintaining global rinderpest freedom

  • 1. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy FAO’s Commitment to maintaining GlobalFAO’s Commitment to maintaining Global Rinderpest FreedomRinderpest Freedom Samia Metwally Animal health officer (Virology)Animal health officer (Virology) Animal Production and Health DivisionAnimal Production and Health Division Rinderpest co-secretariatRinderpest co-secretariat FAO of the United NationsFAO of the United Nations
  • 2. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Content • Global rinderpest eradication program • Current issues • Post-eradication to maintain freedom
  • 3. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Eradication Collaboration between all partners Member Countries FAO GREP OIE OIE Pathway Validate Dossiers Submission of Dossiers Assist activity implementations RECs Financial support by multiple donors
  • 4. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Last outbreaks of rinderpest in Asia, Europe and Middle East Europe – Italy (Roma !!) 1949 Asia – Japan 1924 – China 1956 – Bangladesh 1958 – Vietnam 1977 – Mongolia 1992 – India 1995 – Pakistan 2000 Middle East – Saudi Arabia 1997 – Iraq and Turkey 1996
  • 5. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy 2011 Declaration of Rinderpest Global Freedom
  • 6. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy There is no longer room to doubt that Rinderpest has been eradicated from the world There is no longer room to doubt that Rinderpest has been eradicated from the world Rinderpest virus is currently kept in many laboratories in many countries
  • 7. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy 2011: Priorities of Post-Eradication 1. approval of a minimum number of facilities for holding rinderpest virus and vaccine 2. develop a rinderpest virus sequestration policy 3. destroy rinderpest-virus containing material or store it in a minimum number of approved facilities 4. awareness raising and ensure secure handling of rinderpest virus-containing material 5. essential research projects- approved by FAO and OIE 6. adequate surveillance systems, national preparedness and non-infectious diagnostic tests 7. international preparedness plan
  • 8. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy June 2012: Established FAO-OIE Rinderpest Joint Advisory Committee and Rinderpest Secretariat
  • 9. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Moratorium on Rinderpest Virus o FAO/OIE press releases: ‘call for countries to comply with moratorium on research using live virus’ (July 2012) o FAO/OIE Press release: ‘Moratorium on using live rinderpest virus lifted for approved research’ (July 2013)
  • 10. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Established FAO-OIE rinderpest holding facilities
  • 11. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy FAO Project (USA- funded 2015-16) Objective 1: Increased coordination of rinderpest post- eradication activities and raising awareness Objective 2: Increased sequestration and destruction of rinderpest virus Objective 3: Disease surveillance systems at national, regional and global levels
  • 12. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy - Raise public awareness for three target audiences • Livestock holders, wildlife handlers and community leaders • Governments (veterinary authorities and lab personnel) • Academia • Regional community outreach- Africa and Asia Communication and Advocacy Keeping Rinderpest on the Radar Screen
  • 13. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Regional Community outreach • Regional Meeting for Africa, Sharm al Sheikh, Egypt 5-6 August – 9 countries attended plus RHFs and international organizations, AU-IBAR – The five countries keeping the virus agreed to destroy or sequester their virus – All countries agree to work with FAO to raise awareness for rinderpest – Countries pledged to destroy and sequestrate the virus before 2018 – Focal points for virus destruction and raising awareness – One country was reluctant to transfer their virus (now onboard) – New countries reported to keep vaccine stock
  • 14. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Facilitate and Encourage Virus Destruction and Sequestration  Facilitate virus sequestration and destruction  Analyze questionnaire data (vaccine and wild-type virus)  Develop Disease spread model – demonstrate the impact  Support to countries holding rinderpest virus: flexible support options Expert team missions; Africa and Asia Procurement of laboratory consumables and equipment to enable destroying stocks Transfer of virus to the established FAO-OIE holding facilities  Equipment procured to support the FAO-OIE RHFs
  • 15. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy FAO Support Virus Transfer/Destruction/ Facility Decontamination • SOPs on virus destruction, shipping, lab decontamination • Facilitate shipping and freight cost • Provide biosafety/biosecurity training on site • Deploy experts team for assistance • Provide equipment (i.e.) biosafety cabinet and/or portable autoclave We can assist immediately rinderpest-secretariat@fao.org +39 06 570 55838
  • 16. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Countries destroyed or sequestered their virus stock in 2015 – Botswana: • Two shipments of vaccine virus seed to to Botswana to FAO-OIE RHF at AU-PANVAC- long process 8 months to complete – Australia: • Destroyed their stock last month – Sudan: • Final arrangements to ship their stock to AU-PANVAC
  • 17. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Disease surveillance systems at national, regional and global levels Detect and report any emergence of rinderpest Include rinderpest in the differential diagnosis and rule out with look alike diseases Disease recognition
  • 18. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy Areas that need support… • Continue virus destruction and sequestration efforts USD160,000 • Post Rinderpest eradication outreach and education USD60,000 • International Preparedness Plan – Funding to support a consultant on its development USD30,000 – Convene a stakeholders’ consultation on emergency funding USD50,000 – Conduct national simulation exercises in high-risk regions USD 120,000 • Vaccine production, regional vaccine banks – Develop a policy and strategy for providing vaccine in the case of an outbreak (type, doses, geographic locations, mechanism of activation and delivery, etc) USD20,000 – Secure funding for vaccine stockpile USD 1 Million • Manage and deploy a non-infectious diagnostic tool USD200,00018
  • 19. Maintaining Global Freedom from Rinderpest International Meeting • 20-22 January 2016 • Rome, Italy

Editor's Notes

  1. Continuing virus destruction and sequestration efforts – this includes continuing efforts on the part of the expertise from the JAC where funds are needed to hold the meetings of the experts, as well as missions for assistance in the destruction of the material and laboratory clean up, or in the transfer of material. Furthermore these efforts can also include the evaluation and assessment of facilities that are already rinderpest holding facilities or those that wish to become one on behalf of the international community. Outreach and education – despite the disease being eradicated there is still a need to keep up education around the clinical signs of the disease – especially given the nature and the appearance of lesions that can be similar to FMD and peste des petits ruminants. Furthermore, an update to the rinderpest eradication video is helpful taking into consideration the efforts that can be undertaken at the laboratory level to destroy or sequester the existing material, along with examples of the clinical signs of the disease. This type of outreach and education can be distributed in a variety of means in any event, it would be helpful in ensuring rinderpest remains a part the outreach. Diagnostic tool - a diagnostic tool is ready to be developed by the Plum Island facility – the OIE and the FAO have received recommendations from the JAC to approve the project. Once developed the management and the deployment of the diagnostic tool would be required as a rapid detection method.