Vaccine security Meeting Rome Italy FAO HQ 23-24 January 2020 Pillar I - Improve\1.3 Emerg Vacc\Vaccine Security Meeting\PPTs final

1. Vaccine Security for
Rinderpest
Samia Metwally
Senior Animal Health Officer
Food and Agriculture Organization of the UN

2. CONTENTS
1. FAO and OIE rinderpest post-eradication priorities
2. Procedures for designation of rinderpest holding facilities
3. Rinderpest vaccine reserve and seed bank
4. Activation of the vaccine reserves and vaccine deployment

3. Rinderpest: its impact and risk
Everyone here knows about rinderpest (??)
But for how much longer?

4. Rinderpest virus stored in Laboratory 2011
35 + 1 countries

5. Post-eradication priorities
1. Approval of a minimum number of
joint facilities to holding rinderpest
virus stocks and vaccine reserve
2. Development of a rinderpest virus
sequestration policy
3. Advocacy for virus destruction and
sequestration
4. Raising awareness among
stakeholders
5. Adequate surveillance
systems/rumor tracking
6. Vaccine reserves, seed bank and
diagnostics
7. Essential research projects
8. Global rinderpest action plan

6. FAO-OIE Rinderpest Holding Facilities
Categories
• A) Rinderpest Holding Facility for storing rinderpest virus
containing material, excluding vaccine stocks;
• B) Rinderpest Vaccine Holding Facility for storing only
manufactured vaccines, vaccine stocks and material
solely for their production.

7. retain an up-to-date inventory of
vaccine stocks for the region
validate or destroy stocks of expired
vaccines
regularly test the quality of the vaccines
in accordance with the OIE guidelines
contribute, when requested by FAO and
the OIE, to the global rinderpest vaccine
bank and preparedness strategy
accept vaccine virus seeds or stocks
from FAO and OIE Member Countries for
safe storage and/or for destruction
FAO-OIE Holding Facility Mandate (Category B - vaccine)
Rinderpest Vaccine Holding Facility for storing only manufactured vaccines,
vaccine stocks and material solely for their production.

8. Process for Designation of FAO-OIE Rinderpest Holding Facilities
l
Submission
- Application form
- Declaration of interest by gov
- Rinderpest national
Contingency plan
- Facility biosafety manual
Evaluation
- Review application by JAC
- Facility inspection by an
expert team
-Review inspection report by
JAC
- Recommendation by JAC to
FAO- OIE
FAO-OIE
provisional
approval
OIE- member
approval at GS
FAO- Internal policy
and membership
notification
Facility
Designation

9. Site Inspections of Holding Facilities

11. Rinderpest Vaccine Reserve
• AU-PANVAC
• NIAH – Japan
• In the pipeline- FAO vaccine reserve - IZS Institute, Italy
Vaccine Seed Bank
• FAO rinderpest vaccine seed bank in CIRAD- ongoing
• NIAH vaccine send bank - Japan
Vaccine Production
- Published the criteria for selection of vaccine
manufacturers
- Selection of manufacturers
In the pipelines
• Activation of the bank
• Deployment of vaccine
• Extension of shelf life
Rinderpest Vaccine

12. Response to Outbreaks- vaccine & vaccination
• The national authority in the affected
country submits the “Official Request for
Vaccine” to the Rinderpest Secretariat.
• FAO and OIE to assess the request, and
if accepted, the Rinderpest Secretariat
liaises with the RHFs to facilitate vaccine
deployment and shipping procedures.

13. Acknowledgements
• FAO-OIE Rinderpest Secretariat
• Joint advisory committee members
• FAO and OIE country and regional offices
• Partner organizations and countries
Development partners
- Defense Threat Reduction Agency, USA
- Government of Japan Cooperative Programme

14. Thank You for Your Attention