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Unit-I
EYE (Vision)
Eye
Course No. – VPB 1st Professional year
Credit Hrs. – 4+1=5
Date: 07.06.2021
Dr. Pramod Kumar
Asstt. Professor
Dept. of Veterinary Physiology
BVC, Patna
Diagram of an eye:
The mucosal tissue around the anterior & lateral portions
of the eye is conjunctiva
Cornea is the outer of the anterior part of the eye which is
clear & transparent
Sclera is the opaque continuation of the posterior most of
the eye
Snell`s law:
It states that the light striking a transmitting medium of
greater refractive index will bend the light toward the ┴ to
the interface of the medium
Greater the refractive index greater the optical density &
greater the capability of that medium to bend light
The focusing power of a lens is measured in diopter
Emmetropic- When the optics of the eye will result in║to light
rays focusing precisely on the retina
Myopic- When the light rays focus in front of the retina, the
focus can be corrected with concave lens
Hyperopic- When the light rays focus behind the retina & can
be corrected with convex lens
Retina structure & function:
The 3 functional layers of the retina are ganglion cell layers,
bipolar cell layer & photoreceptor layers
They are arranged in such a way that light will absorb or
reflect by the intervening structures without contributing
the image function
Tapetum lucidium ↑ the %age of light intensity at the
photoreceptors
Photoreceptor-
It consists of rod & cones and they are named according to
their shape
Rods are sensitive to dim light & are denser in the
peripheral portion of retina in diurnal animals
In nocturnal animals, they present denser in the central
portions of the retina
The rod contains a visual pigment called rhodopsin
Cones are responsible for color vision & are densest in the
central region of the retina in the fovea
Generation of receptor potential:
The receptor potential of rod & cone cells are
generated by reactions which are initiated by light being
absorbed by chemicals called visual pigments
Electroretinography- It is an electro-diagnostic test which
measures the electrical activity of the retina in response to
a light stimulus
Color vision-
❖ It seems to be a sensory capacity found in most species at
least they should have 2 photopic visual pigments
❖ For genesis of receptor potential begins with the bleaching
of the visual pigment, a number of ionic &
neurotransmitter release
❖ Due to an electrogenic Na-K pump in the inner segment
↑ing extracellular Na+, a steady current flow from the inner
to outer portion of the segments
❖ During light there is ↓ in Na+ conductance in the outer
segment resulting in a hyper-polarization of the receptor &
steady release of neurotransmitter from the
photoreceptors in the dark & hyper-polarization stops the
release & interpreted as light stimulation
❖ Retina is responsible for contrast enhancement, detection
of movement & large changes in luminance
❖ Bipolar cells synapse with the photoreceptors on one end &
the ganglion & amacrine cells on the other
❖ Bipolar cells tend to have a small receptive field &
constitute a vertical transmission component of the retina
❖ Horizontal cells function primarily in lateral inhibition in the
retina & are integral to both centre surround fields &
directional sensitivity circuits
❖ Horizontal cell circuits have the effect of inhibiting the
transmission of visual stimulus information & when moves
across the retina allow to pass the information in the
preferred direction
❖ Amacrine cells have many types of receptive fields that are
sensitive to movement or onset of visual stimuli
❖ Ganglion cells have axons that forms the optic nerve,
chiasm & tract
❖ These are receptive to the off & on of light stimuli
integrates the color contrast enhancement while others
respond to preferred directional movement
Neurotransmitters-
➢ A no. of neurotransmitters are present in the retina
➢ Ach is found in some amacrine cells
➢ Dopamine is found in amacrine, horizontal & bipolar cells
➢ Dopamine & serotonin are involved in red-green color
discrimination
➢ Substance P, somatostatin & glutamate are also present in
the retina
➢ Glutamate is the recognizable & probable neurotransmitter
of the photoreceptors

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Eye Anatomy and Physiology

  • 1. Unit-I EYE (Vision) Eye Course No. – VPB 1st Professional year Credit Hrs. – 4+1=5 Date: 07.06.2021 Dr. Pramod Kumar Asstt. Professor Dept. of Veterinary Physiology BVC, Patna
  • 3.
  • 4. The mucosal tissue around the anterior & lateral portions of the eye is conjunctiva Cornea is the outer of the anterior part of the eye which is clear & transparent Sclera is the opaque continuation of the posterior most of the eye Snell`s law: It states that the light striking a transmitting medium of greater refractive index will bend the light toward the ┴ to the interface of the medium Greater the refractive index greater the optical density & greater the capability of that medium to bend light The focusing power of a lens is measured in diopter Emmetropic- When the optics of the eye will result in║to light rays focusing precisely on the retina
  • 5. Myopic- When the light rays focus in front of the retina, the focus can be corrected with concave lens Hyperopic- When the light rays focus behind the retina & can be corrected with convex lens Retina structure & function: The 3 functional layers of the retina are ganglion cell layers, bipolar cell layer & photoreceptor layers They are arranged in such a way that light will absorb or reflect by the intervening structures without contributing the image function Tapetum lucidium ↑ the %age of light intensity at the photoreceptors Photoreceptor- It consists of rod & cones and they are named according to their shape Rods are sensitive to dim light & are denser in the peripheral portion of retina in diurnal animals
  • 6. In nocturnal animals, they present denser in the central portions of the retina The rod contains a visual pigment called rhodopsin Cones are responsible for color vision & are densest in the central region of the retina in the fovea Generation of receptor potential: The receptor potential of rod & cone cells are generated by reactions which are initiated by light being absorbed by chemicals called visual pigments Electroretinography- It is an electro-diagnostic test which measures the electrical activity of the retina in response to a light stimulus Color vision- ❖ It seems to be a sensory capacity found in most species at least they should have 2 photopic visual pigments
  • 7. ❖ For genesis of receptor potential begins with the bleaching of the visual pigment, a number of ionic & neurotransmitter release ❖ Due to an electrogenic Na-K pump in the inner segment ↑ing extracellular Na+, a steady current flow from the inner to outer portion of the segments ❖ During light there is ↓ in Na+ conductance in the outer segment resulting in a hyper-polarization of the receptor & steady release of neurotransmitter from the photoreceptors in the dark & hyper-polarization stops the release & interpreted as light stimulation ❖ Retina is responsible for contrast enhancement, detection of movement & large changes in luminance ❖ Bipolar cells synapse with the photoreceptors on one end & the ganglion & amacrine cells on the other ❖ Bipolar cells tend to have a small receptive field & constitute a vertical transmission component of the retina
  • 8. ❖ Horizontal cells function primarily in lateral inhibition in the retina & are integral to both centre surround fields & directional sensitivity circuits ❖ Horizontal cell circuits have the effect of inhibiting the transmission of visual stimulus information & when moves across the retina allow to pass the information in the preferred direction ❖ Amacrine cells have many types of receptive fields that are sensitive to movement or onset of visual stimuli ❖ Ganglion cells have axons that forms the optic nerve, chiasm & tract ❖ These are receptive to the off & on of light stimuli integrates the color contrast enhancement while others respond to preferred directional movement Neurotransmitters- ➢ A no. of neurotransmitters are present in the retina ➢ Ach is found in some amacrine cells
  • 9. ➢ Dopamine is found in amacrine, horizontal & bipolar cells ➢ Dopamine & serotonin are involved in red-green color discrimination ➢ Substance P, somatostatin & glutamate are also present in the retina ➢ Glutamate is the recognizable & probable neurotransmitter of the photoreceptors