Kigali | Sep-15 | UN SE4ALL: Scotland’s ContributionSmart Villages
By S. M. Kasanga
To help collect and distil the knowledge and experience from the last 15 months of engagement in East Africa, a concluding workshop was held in Kigali, Rwanda. The workshop brought together over 40 government representatives and other key stakeholders from across the region to share information on progress and remaining challenges, and to reflect on lessons learned.
More info: http://e4sv.org/events/east-africa-workshop/
Kigali | Sep-15 | UN SE4ALL: Scotland’s ContributionSmart Villages
By S. M. Kasanga
To help collect and distil the knowledge and experience from the last 15 months of engagement in East Africa, a concluding workshop was held in Kigali, Rwanda. The workshop brought together over 40 government representatives and other key stakeholders from across the region to share information on progress and remaining challenges, and to reflect on lessons learned.
More info: http://e4sv.org/events/east-africa-workshop/
Presentation by Marcella Maher Keogh on Better Energy communities at the launch of the Unlocking the energy Efficiency Opportunity report 2015.
The seminar presented new insights including the scale of the energy efficiency opportunity; the costs and benefits of 2020 target achievement; and policy options based on a new analysis of investor behaviour and decision-making.
The launch of the report was accompanied by presentations from exemplar projects from the SEAI energy efficiency programmes and a panel discussion exploring how we might accelerate the pace of retrofit in Ireland. New insights into the attitudes of investors was presented and the multiple benefits of energy efficiency explored.
Benjamin Sovacool "The Nordic Low-Carbon Transition: Implications and Insights for Researchers and Practitioners" Keynote Energy Cultures Conference 2016
The European Investment Bank (EIB) has launched ambitious new climate strategy and Energy Lending Policy. What does it mean for the energy future of both EU and the world? Read more in out blog!
Cecilia Ledesma is Senior Programme Officer at the International Center on Small Hydro Power (ICSHP). ICSHP, under auspices of United Nations Industrial Development Organization (UNIDO) and China's Ministry of Water Resources, promotes small hydro power development worldwide. Projects focus on training and capacity building to facilitate rural electrification and sustainable economic development in developing countries. She holds a Bachelor’s Degree in Environment, Economics and Politics (EEP) from Claremont McKenna College.
In this presentation, Cecilia Ledesma will talk about small hydro power as a case study, demonstrate how renewable energy is applicable and relevant for communities across different contexts
Our Energy Guelph (OEG) is a community-led group established by the Guelph City Council to determine stakeholder priorities, establish metrics for progress, & update Guelph's Community Energy Initiative.
During the spring and summer of 2017, OEG engaged with community members, seeking input into Guelph’s community energy plan. Community engagement represents one of three primary inputs and activities that will come together to inform Guelph's community energy plan.
Towards 100% sustainable energy on the Caribbean island of SabaAnna Hickman
The story of how a Caribbean island is transforming its energy mix to embrace renewables is now available for you to share widely in a LEDS GP slide pack
Steve Cochran, Blue Ridge Sustainability Institure Principle and Energy Action Council Steward, describes efforts to mobilize the business and financial communities in support of energy upfit activities.
Presentation by Marcella Maher Keogh on Better Energy communities at the launch of the Unlocking the energy Efficiency Opportunity report 2015.
The seminar presented new insights including the scale of the energy efficiency opportunity; the costs and benefits of 2020 target achievement; and policy options based on a new analysis of investor behaviour and decision-making.
The launch of the report was accompanied by presentations from exemplar projects from the SEAI energy efficiency programmes and a panel discussion exploring how we might accelerate the pace of retrofit in Ireland. New insights into the attitudes of investors was presented and the multiple benefits of energy efficiency explored.
Benjamin Sovacool "The Nordic Low-Carbon Transition: Implications and Insights for Researchers and Practitioners" Keynote Energy Cultures Conference 2016
The European Investment Bank (EIB) has launched ambitious new climate strategy and Energy Lending Policy. What does it mean for the energy future of both EU and the world? Read more in out blog!
Cecilia Ledesma is Senior Programme Officer at the International Center on Small Hydro Power (ICSHP). ICSHP, under auspices of United Nations Industrial Development Organization (UNIDO) and China's Ministry of Water Resources, promotes small hydro power development worldwide. Projects focus on training and capacity building to facilitate rural electrification and sustainable economic development in developing countries. She holds a Bachelor’s Degree in Environment, Economics and Politics (EEP) from Claremont McKenna College.
In this presentation, Cecilia Ledesma will talk about small hydro power as a case study, demonstrate how renewable energy is applicable and relevant for communities across different contexts
Our Energy Guelph (OEG) is a community-led group established by the Guelph City Council to determine stakeholder priorities, establish metrics for progress, & update Guelph's Community Energy Initiative.
During the spring and summer of 2017, OEG engaged with community members, seeking input into Guelph’s community energy plan. Community engagement represents one of three primary inputs and activities that will come together to inform Guelph's community energy plan.
Towards 100% sustainable energy on the Caribbean island of SabaAnna Hickman
The story of how a Caribbean island is transforming its energy mix to embrace renewables is now available for you to share widely in a LEDS GP slide pack
Steve Cochran, Blue Ridge Sustainability Institure Principle and Energy Action Council Steward, describes efforts to mobilize the business and financial communities in support of energy upfit activities.
RI/USAID International H2O Collaboration - Partnering for SuccessRotary International
The Rotary International-USAID International H2O Collaboration is a partnership between Rotary and the U.S. Agency for International Development that supports lasting, positive change to water, sanitation, and hygiene (WASH) initiatives. Rotarians will discuss successes and challenges in their work with this major international development agency in Ghana, Uganda, and Madagascar. You’ll hear some of the lessons learned in the partnership planning and design phase and learn about opportunities for advocacy and innovation in service.
Session 2 - National Energy Research and Policy Conference 2022SustainableEnergyAut
Presentations from:
Dr Bernadette Power
Dr Gary Goggins
Jean-Pierre Roux
Dr Noreen Brennan
Dr Niall Dunphy
Katie Harrington
Dr Róisín Moriarty
Dr Brian Caulfield
The Deal, Alison McKenzie-Folan (Deputy CEO and Digital Transformation Lead, ...mysociety
Wigan are trying something new: a contract between residents and the council as both sides strive for a better borough. Alison shares the lessons and impacts so far.
This presentation was made at mySociety's TICTeC Local conference on 6th November 2018. More information about TICTeC Local can be found here: https://tictec.mysociety.org/local
Safe Water Gardens - Safe Sanitation for All - Pitch Deck V9Tim-Frederik Kohler
A Safe Water Garden (SWG) is a scalable sewage treatment system developed from an original UNICEF concept. It suits individual households, as well as small community centres like rural schools.
A highly dedicated team devotes its time to build up a network of Safe Water Gardens in Indonesia.
We have the vision to scale it up to build 100 Million of these gardens across developing rural tropical Asia and beyond.
Our business team at SEAI will take you through education supports, energy audit voucher,s and grant supports for businesses who want to save energy and reduce their bills. You will also learn about how you can fund your renewable energy transition.
The SEAI Fellowship pilot programme will provide the opportunity for postdoctoral or experienced researchers to apply for research fellowship positions based within SEAI.
This webinar will help you understand:
How to reduce your energy use and bills this winter.
SEAI supports and grants to help you further reduce costs and move away from fossil fuels.
How to fund your renewable energy transition.
The objective of this training will be to introduce contractors to the fundamentals of Quality Management Systems and to help them to understand how they can assist contractors in providing quality service to our Homeowners.
This is a stakeholder engagement webinar in relation to identifying a suitable energy education service provider(s), to provide Management and Administrative Services to support the delivery of the SEAI School Workshop Programme.
The webinar will outline how SEAI can help and support committed public bodies now and in the long term to achieve 2030 targets. SEAI are delighted to have Jan Rosenow, Director of European Programmes at the Regulatory Assistance Project, addressing the current drivers for climate action and why it is an imperative strategic concern for all businesses, public and private. Peter Smyth, Assistant National director in the HSE Capital and Estates Department will cover their journey from ad hoc once-off projects dependent on annual budgets, to a strategic HSE Infrastructure Decarbonisation Roadmap.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. DUNLEER SEC
County Louth
• Population 2700
• County of 130,000 residents
• Situated 30 kilometers north of Dublin City
• County Louth borders with Northern Ireland
5. Life In Colour Is
Good!
The Colour is Vanishing from
Our World
Live Life in Colour
6. Global Co2 levels at highest ever
recorded
Deforestation Greta Thunberg Sweden
Climate change protest Dublin
Ireland declares emergency
• Citizens Assembly
• Joint committee on
climate action
• Climate action plan 2019
10. P.P.N.
Leader
Financial supports target of 3% interest
Credit Unions
Banks
Community Funding
Private
Mentor programme next steps are good
National Panel
Regional Mentors
County Mentors
Establishing SECs needs proper
funding
Community Enhancement Programmes
Town and Village programme
Ways to show leadership
S.E.C. standards
Be more professional
Action oriented
Inclusive and diverse
Partner more
Be a forcefully lobby
Public Funding channels
Need to move to a solutions mindset
Challenge internal processes, systems and
timelines
Retrofit project mng. fees of 20%
Proposed National steering group is a
positive step
15. Services: Based on our track record of success we can provide you with:
• Education: An interactive enjoyable education programme that will inspire
people in your community to join with you in taking action on climate
change ( To date 70% of attendees have signed up to community retrofit programmes)
• Community retrofits: Assist, support and capacity building for your
Sustainable Energy Community to successfully deliver a community retrofit
programme
• Energy master plan: The preparation of an energy master plan that delivers
practical solutions you can act on
• Generation: Advise you in your move towards community generation