All you want to know about synchronization of estruous

1. Estrous Synchronization/ Control of
Ovulation

2. Estrus synchronization
• What is estrus synchronization?
• It is defined as bringing a group of animals
in to estrus at a time
• In simplest meaning , to bring an animal in
to heat at the will of the herd owner.

3. Methods
• Extending of luteal phase – long term
administration of P4 for 10 days
• Shortening of luteal phase – by luteolytic
agent e.g. PGF2α and estrogens and its
analogues

4. ESTRUS SYNCHRONIZATION
• Beneficial to both:
• 1) Herdsmen
• 2) Researchers
Effective Estrus Detection Requires:
 Much time
 Patience
 Skill
 Expense
 Coordination / Harmony

5. Benefits for improvements in herd
productivity & Reprod. Efficiency
1) Breeding Management:
- Advantage of concentrating breeding
- Scheduled calving intervals
- Maximizing use of A.I.
 Predict time of estrus (Timed A.I. without estrus
detection)
 Shortening of parturitions period in seasonal
breeders.
 Increase in 1st service conception rate in
seasonal breeders.

6. Improve Reproductive Efficiency in herd.
Where estrus detection is a problem
Pregnancy rate=
No. of Cows Pregnant = ?
= No. of cows (breedable )x Rate of heat detection x Pregnancy rate .
Cows=100, heat detection rate=50%, CR= 50%;
No. of cows pregnant (100x50/100 x50/100) = 25
• Now by synchronization:
• If heat detection rate becomes 100%
• Even if CR decreases by 40%, then
• No. of cows pregnant = 100 x 40/100 x 100/100 = 40
• So if 100% syn. is achieved , it takes of pressure of
heat detection and
• So breeding can be planned.

7. ADDITIONAL BENEFITS
Facilitates use of technique of embryo transfer.
Breeding control for controllable lactation.
Weaning, fattening and marketing of uniform
group of animals
Best use of labour, building and other
resources
Feeding of animals in uniform groups
Decreased mortality

8. Estrus synchronization should be:
1. Effective
2. Simple to administer
3. Relatively fool proof
4. Acceptable cost benefit ratio
5. No harmful effects

9. Species Drugs Treatment Regimen End of
treatment to
estrus
(Days)
Breeding /AI
time (without
reference to AI)
Cattle
and
Buffalo
PGF Two injections (11 to 12 days
apart)
3 -5 72 and 96 h
Cattle Progestogen +
PGF
Progestogen(days 1-7 ),
PGF(day 6 )
2-3 84 h
Progestogen+
Estrogen
Progestogen+ Estrogen inj (
day 1 ) and progestagen
implant (days 1-9 )
3-5 54 h
aGnRH + PGF * Inject aGnRH (day 0 ), PGF
(day 6)
2-4 24 -72
aGnRH + PGF +
aGnRH **
Inject aGnRH (day 0 ), PGF
(day 7), aGnRH (Day 8or 9)
2-4 24-48 h
Sheep Progestogen
(pessary) + eCG
Progestogen(12-14 days ),
eCG( day of pessary removal)
2 48-60 h
PGF Two injections (9 days apart) 2-3 48 h
Estrus synchronization methods in cyclic farm animals

10. Goat Progestogen
(pessary) +
eCG
Progestogen(18-21 days ),
eCG( day of pessary
removal)
2-3 30-48 h
PGF Two injections (11-12 days
apart)
2-3 48 h
Swine Progestogen
in feed $$
Alrrenogest (14-18 days) 4-6 Day 6
and 7
Horse Progestogen
in feed
Alrrenogest (15 days) 4-7
PGF One dose to mares in
diestrus
3-5
PGF + hCG PGF (day 1 ), hCG (days 7-8
), PGF (Day 15), hCG( day
21-22)
2-4
All animals may be bred at detected estrus
** Better protocol compared to * for timed A.I
$$ Not useful in cyclic swine

11. Estrus synchronization in donor and recipients
Day Time Treatment - 1 Treatment - 2 Treatment - 3
10 AM 25000 I.U. PMSG 5 mg FSH 5 mg FSH
PM - 5 mg FSH 5 mg FSH
11 AM - 4 mg FSH 5 mg FSH
PM Recipients receive
PG
4 mg FSH 5 mg FSH
12 AM Donors receive PG 3 mg FSH 5 mg FSH
PM - 3 mg FSH 5 mg FSH
13 AM - 2 mg FSH 5 mg FSH
PM - 2 mg FSH 5 mg FSH
14 AM - - -
PM A.I. A.I. A.I.
15 AM A.I. A.I. A.I.
PM A.I. A.I. A.I.

12. Conclusion
• PGF2 α natural (25-30 mg), synthetic analogue(500µg )
• are effective luleolytic in animal having mature CL (6-16
days) of cycle, during gestation PCL due to uterine
pathology
• In non-pregnant carrying receptic CL, oestrus within 32-
96 hours inseminate, acceptable fertility.
• - effective in superovulation, synchronization
• - in fetal mummification, pyometra and endometritis.
• - inaccurate CL identification if treated with PG cause
waste of drug, labour and semen.
• - be aware of nutritional & reproductive health status
of herd.
• Because PGs donot work in non-cycling & underfed
animals

13. THANK YOU VERY MUCH