The document provides equivalent dosing information for various drug classes used to treat diabetes, acid reflux, high cholesterol, high blood pressure, and asthma. It lists common drugs within each class and their equivalent doses to one another. Ranges of typical daily dosages are also provided for each drug. The drug classes covered include sulphonylureas, proton pump inhibitors, inhaled corticosteroids, statins, angiotensin receptor blockers, ACE inhibitors, and beta blockers.

1. Ph. Salman Almalki
‫اﻟﺳﻌودﯾﺔ‬ ‫اﻟﻌرﺑﯾﺔ‬ ‫اﻟﻣﻣﻠﻛﺔ‬
‫اﻟﺻﺣﺔ‬ ‫وزارة‬
‫ﺑﺎﻟرﯾﺎض‬ ‫اﻟﺻﺣﯾﺔ‬ ‫ﻟﻠﺷؤون‬ ‫اﻟﻌﺎﻣﺔ‬ ‫اﻟﻣدﯾرﯾﺔ‬
‫اﻟﻌﺎم‬ ‫ﺿرﻣﺎء‬ ‫ﻣﺣﺎﻓظﺔ‬ ‫ﻣﺳﺗﺷﻔﻰ‬
‫اﻟﺻﯾدﻟﯾﺔ‬ ‫اﻟرﻋﺎﯾﺔ‬
Equivalent Doses
Sulphonylureas :
Glibenclamide Gliclazide Gliclazide MR Glimepiride
2.5 mg bid 40 mg bid 30 mg daily 1 mg daily
5 mg bid 80 mg bid 60 mg daily 2 mg daily
7.5 mg bid 120 mg bid 90 mg daily 3 mg daily
10 mg bid 160 mg bid 120 mg daily 4 mg daily
 One 80 mg Gliclazide tablet is equivalent to one 30 mg Glicalazide MR tablet .
Dosage range :
 Glibenclamide 2.5-20 mg daily in 2 divided doses
 Gliclazide 40-320 mg daily in 2 divided doses
 Gliclazide MR 30-120 mg daily
 Glimepiride 1-4 mg daily
‫ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬‫ـــــــــــــــــ‬
Proton-pump Inhibitors :
Esomeprazole Omeprazole Pantoprazole
10 mg daily 20 mg daily
20 mg daily 20 mg daily 40 mg daily
40 mg daily 40 mg daily
Dosage range :
 Esomeprazole 20-40mg daily
 Omeprazole 10-40mg daily
 Pantoprazole 20-40mg daily
DDI :
 Warfarin
 Phenytoin
 BenzoDiazepines

2. Ph. Salman Almalki
‫اﻟﺳﻌودﯾﺔ‬ ‫اﻟﻌرﺑﯾﺔ‬ ‫اﻟﻣﻣﻠﻛﺔ‬
‫اﻟﺻﺣﺔ‬ ‫وزارة‬
‫ﺑﺎﻟرﯾﺎض‬ ‫اﻟﺻﺣﯾﺔ‬ ‫ﻟﻠﺷؤون‬ ‫اﻟﻌﺎﻣﺔ‬ ‫اﻟﻣدﯾرﯾﺔ‬
‫اﻟﻌﺎم‬ ‫ﺿرﻣﺎء‬ ‫ﻣﺣﺎﻓظﺔ‬ ‫ﻣﺳﺗﺷﻔﻰ‬
‫اﻟﺻﯾدﻟﯾﺔ‬ ‫اﻟرﻋﺎﯾﺔ‬
Inhaled Corticosteroides :
Fluticasone (Total Daily Dose ) Budesonide (Total Daily Dose )
100 mcg 200 mcg
200-250 mcg 400 mcg
400-450 mcg 800 mcg
Dosage range :
Fluticasone Budesonide
Mild asthma 100-250 mcg bid
Moderate asthma 250 mcg bid 100-400 mcg
Severe asthma 500 mcg bid Up to 800 mcg daily

3. Ph. Salman Almalki
‫اﻟﺳﻌودﯾﺔ‬ ‫اﻟﻌرﺑﯾﺔ‬ ‫اﻟﻣﻣﻠﻛﺔ‬
‫اﻟﺻﺣﺔ‬ ‫وزارة‬
‫ﺑﺎﻟرﯾﺎض‬ ‫اﻟﺻﺣﯾﺔ‬ ‫ﻟﻠﺷؤون‬ ‫اﻟﻌﺎﻣﺔ‬ ‫اﻟﻣدﯾرﯾﺔ‬
‫اﻟﻌﺎم‬ ‫ﺿرﻣﺎء‬ ‫ﻣﺣﺎﻓظﺔ‬ ‫ﻣﺳﺗﺷﻔﻰ‬
‫اﻟﺻﯾدﻟﯾﺔ‬ ‫اﻟرﻋﺎﯾﺔ‬
Statins :
Pravastatin Simvastatin Atorvastatin Rosuvastatin
10 mg daily 10 mg daily 10 mg daily 5 mg daily
10-20 mg daily 20 mg daily 20 mg daily 10 mg daily
20 mg daily 40 mg daily 40 mg daily 10-20 mg daily
40 mg daily 80 mg daily 80 mg daily 40 mg daily
Dosage range :
 Pravastatin 10-40 mg daily (night )
 Simvastatin 10-80 mg daily (night )
 Atorvastatin 10-80 mg daily (Any time )
 Rosuvastatin 5-40 mg daily (Any time )

4. Ph. Salman Almalki
‫اﻟﺳﻌودﯾﺔ‬ ‫اﻟﻌرﺑﯾﺔ‬ ‫اﻟﻣﻣﻠﻛﺔ‬
‫اﻟﺻﺣﺔ‬ ‫وزارة‬
‫ﺑﺎﻟرﯾﺎض‬ ‫اﻟﺻﺣﯾﺔ‬ ‫ﻟﻠﺷؤون‬ ‫اﻟﻌﺎﻣﺔ‬ ‫اﻟﻣدﯾرﯾﺔ‬
‫اﻟﻌﺎم‬ ‫ﺿرﻣﺎء‬ ‫ﻣﺣﺎﻓظﺔ‬ ‫ﻣﺳﺗﺷﻔﻰ‬
‫اﻟﺻﯾدﻟﯾﺔ‬ ‫اﻟرﻋﺎﯾﺔ‬
A II – Antagonists :
Valsartan Candesartan Irbesartan Losartan Telmisartan
4 mg daily 75 mg daily 50 mg daily
40 mg daily 8 mg daily 150 mg daily 100 mg daily 40 mg daily
80 mg daily 16 mg daily 300 mg daily 80 mg daily
Dosage range :
 Valsartan 40-320 mg daily
 Candesartan 8-16 mg daily
 Irbesartan 75-300 mg daily
 Losartan 25-100 mg daily
 Telmisartan 20-80 mg daily
‫ــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬‫ــــــــــــــــــــ‬
ACE – Inhibitors :
Captopril Enaapril Lisinopril Perindopril
25 mg daily 5 mg daily 5 mg daily 2.5 mg daily
50-75 mg daily 10 mg daily 10 mg daily 5 mg daily
100 mg daily 20 mg daily 20 mg daily 10 mg daily
150 mg daily 40 mg daily 40 mg daily
Dosage range :
 Captopril 12.5-150 mg daily (in 2 or 3 divided doses)
 Enaapril 2.5-40 mg daily
 Lisinopril 2.5-40 mg daily
 Perindopril 2.5-10 mg daily
‫ــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬‫ــــــــــــــــــــ‬
Beta Blockers :
Atenolol Bisoprolol Carvedilol Metoprolol Propranolol
50 mg 5 mg 25 mg 100 mg 7.5 mg
Beta-1 Beta-1 Beta-1 ,2 Beta-1 Beta-1 ,2