Prostate cancer treatment options range from active surveillance to surgery, radiation, hormone therapy, chemotherapy, immunotherapy, and bone-targeted agents depending on whether the cancer is localized or metastatic. Research into new drugs and therapies is ongoing with over 70 phase III trials recruiting patients. Treatment costs vary significantly between countries and change rapidly as new options become available, with a single patient's 18-year treatment costs estimated at close to 300,000 Euros including drugs, hospital care, and supportive care in later stages of metastatic disease.