Prevention and early detection of Prostate Cancer: a global view Vitaly Smelov, International Agency for Research on Cancer (IARC), World Health Organisation (WHO)
Prevention and early detection of Prostate Cancer: a global view Vitaly Smelov, International Agency for Research on Cancer (IARC), World Health Organisation (WHO)
Maria Russell, MD, surgical oncologist at Winship Cancer Institute of Emory University presents Ocular Melanoma and Liver Metastases at the 2016 CURE OM Patient & Caregiver Symposium.
This slide deck is about Prostate cancer. It is amongst the leading cause of cancer deaths in adult males. This slide deck will provide you with necessary information regarding the symptoms, risk, diagnosis, and possible treatment of prostate cancer. I hope the readers find this slide deck useful & informative
The presentation begins with a brief history of how cancer epidemiology evolved, and what is the status at present. After describing the burden of the disease of cancer globally and in India, the presentation includes a brief description of Cancer causes and prevention including screening activities. It also talks about the national Cancer Registry Program, NPCDCS and NCCP.
Maria Russell, MD, surgical oncologist at Winship Cancer Institute of Emory University presents Ocular Melanoma and Liver Metastases at the 2016 CURE OM Patient & Caregiver Symposium.
This slide deck is about Prostate cancer. It is amongst the leading cause of cancer deaths in adult males. This slide deck will provide you with necessary information regarding the symptoms, risk, diagnosis, and possible treatment of prostate cancer. I hope the readers find this slide deck useful & informative
The presentation begins with a brief history of how cancer epidemiology evolved, and what is the status at present. After describing the burden of the disease of cancer globally and in India, the presentation includes a brief description of Cancer causes and prevention including screening activities. It also talks about the national Cancer Registry Program, NPCDCS and NCCP.
Professor Michael Leitzmann presentation on The Continuous Update Project: Recent Findings on Diet, Nutrition, Physical Activity and Cancer at FENS European Nutrition Conference, 20-23 October 2015 Berlin (Germany).
Cancer is not all about what we inherit-- it's also about what we eat, how much we move and even how we stay connected. This is good news! This talk reviews the evidence for how we can reduce our risk of cancer through simple lifestyle changes.
Nutrition in Cancer Prevention and TreatmentTim Crowe
This presentation will help you to understand the influence that dietary and lifestyle factors play in the prevention and causation of cancer. It outlines the important nutritional considerations for patients undergoing treatment for cancer and reviews procedures to improve patient safety by knowing the risks and benefits of antioxidant supplementation during cancer treatment
Overview and Pharmacotherapy of Prostate Cancer (based on NCCN 2012 guideline...hyunik116
This presentation was the prostate cancer lecture for the oncology therapeutics course (31:725:560) that was presented to the class of 2014 PharmD students at the Ernest Mario School of Pharmacy.
I really enjoyed researching and preparing this lecture for the students, and hope you also will find at least something useful in this presentation.
Developing a cancer survivorship research agenda - Prof Patricia GanzIrish Cancer Society
A presentation given at the Irish Cancer Society's Survivorship Research Day at the Aviva Stadium, Dublin on Thursday, September 20th, 2013.
Developing a cancer survivorship research agenda: challenges & opportunities - Prof Patricia Ganz, UCLA Fielding School of Public Health
This tool will describe the key components of an abstract, offer practical suggestions for optimising the key messages of your work, provide general advice on abstract preparation and tips for increasing the likelihood of your abstract being accepted for presentation.
This tool will describe the key components of an abstract, offer practical suggestions for optimising the key messages of your work, provide general advice on abstract preparation and tips for increasing the likelihood of your abstract being accepted for presentation
How to write an abstract - Online EAUN Course 2022Marc van Gurp
This educational tool is provided to assist you in the development of your abstract, for submission to the European Association of Urological Nurses (EAUN) annual meeting
This tool is provided to assist you in making a poster for the poster session during the European Association of Urological Nurses (EAUN) Annual Meeting.
This tool is provided to assist you in the development of your scientific poster for oral presentation. It describes the key components of the poster presentation, offer practical suggestions for optimising the key messages of your work, provide general advice on poster preparation and tips for its oral presentation.
How to write an abstract - online EAUN courseMarc van Gurp
This tool will describe the key components of an abstract, offer practical suggestions for optimising the key messages of your work, provide general advice on abstract preparation and tips for increasing the likelihood of your abstract being accepted for presentation.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?
EPAD 2017 - Bertrand Tombal
1. Prevention of Prostate Cancer.
An utopia ?
President
European Organisation for Research and Treatment of Cancer (EORTC)
Brussels, BE
Chairman Urology
Cliniques universitaires Saint Luc,
Brussels, BE
2. The goal.
2
Primary prevention aims to prevent disease or
injury before it ever occurs.
e.g. education about healthy and safe habits
drugs
Secondary prevention aims to reduce the impact
of a disease or injury that has already occurred.
e.g. personal strategies to prevent recurrence, or
implementation of programs to return people to
their original health and function to prevent long-
term problems.
Tertiary prevention aims to soften the impact of
an ongoing illness or injury that has lasting
effects.
rehabilitation programs, chronic disease
management programs
support groups that allow members to share
strategies for living well
3. The Magic Pill doesn’t exist; why have we failed ?
Unselected population.
Naïve assumptions on the role of hormones, diet, and
lifestyle.
Pill approach, versus education and precision
approaches.
3
4. The Magic Pill doesn’t exist; why have we failed ?
Hormonal prevention: the dutasteride trial,
Crude rate absolute risk reduction of Pca: 5.1% at 4 years,
But
No difference in PCa or overall mortality
No reduction in the risk of aggressive cancers (i.e., Gleason 7–10)
But
decreased libido (3.3% vs. 1.6%); loss of libido (1.9% vs. 1.3%);
decreased semen volume (1.4% vs. 0.2%); erectile dysfunction
(9.0% vs. 5.7%); gynecomastia (1.9% vs. 1.0%).
4
5. The Magic Pill doesn’t exist; why have we failed ?
5
Chemoprevention with selenium and vitamin E
Large randomized placebo-controlled trial of vitamin
E and selenium.
Show no reduction in PCa period prevalence, but an
increased risk of PCa with vitamin E alone (17%).
6. Paving the future for better prevention strategies
Actions Plan
1. Identify a population any higher risk, then design
prospective trials with new drugs.
2. Enact basic life adjustment at every stage the PCa
care pathway (PRI, SEC, TER prevention)
6
7. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
Gene
Lifestyle
7
SNP Reference
rs4430796
Zheng, N Engl J Med 2008 ; 358 :910-9
Beebe-Dimmer, Int J Cancer 2008 ; 122(12) : 2876-79
Eeles, Nat Genetics 2008 ; 40(3) : 316-21
rs1859962
rs16901979
rs6983267
rs1447295
rs7501939
rs4242382
rs10090154
rs10993994
Eeles, Nat Genetics 2008 ; 40(3) : 316-21
Camp, Canc. Epid. Biomarkers Prev 2009 ; 18(4)
rs266849 Eeles RA et al Nat Genetics 2008 ; 40(3) : 316-21
rs2171492 Ross, BMC Cancer 2009, 9 :69
rs104548 (D302H) Lubahn, The Prostate 2010 ; 70 :646-653
rs9282858 (A49T )
Makridakis NM et al Lancet 1999 ; 354 :975
Li J et al Am J Epidemiol 2010 ; 171 :1-13
rs623419 Lindström S et al Prostate 2006 ; 66 (22) : 11077-83
rs4045402 Lindström S et al Prostate 2006 ; 66 (16) : 1729-43
rs11569681 Thomae BA et al Pharmacogenom J 2002 ; 2 :48
G289S Margiotti K et al The Prostate 2002 ; 53 :65
8. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
Gene
Lifestyle
8
There are men at higher risk of PCa because
they carry germline or somatic gene
abnormalities.
RNASEL, formerly known as HPCI
BRCA1 and BRCA2, which have also been linked to
breast and ovarian cancer in women
MSH2, MLH1, and other DNA mismatch repair
genes
HOXB13
IMPORTANT TO DEFINE A TARGET
POPULATION !
9. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
Gene
Lifestyle
9
It is urgent to produce, validate, and implement
similar recommendations for Prostate Cancer.
10. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
Gene
Lifestyle
10
Evidence Decreases Risk. Increases risk
Suggestive BMI (low grade PCa) BMI (advanced, mortality)
Spirits
Dietary Calcium
Weight
Weak Total vegetable
Fish
Coffee
Serum α-tocopherol
Selenim
Dairy food
Milk
Low-fat milk
Dairy and dietary calcium
Supplement calcium
Waist circumference
Height
Adapted from Markozannes et al. Diet, body size, physical activity and risk of prostate
cancer: An umbrella review of the evidence. Eur J Cancer. 2016 Dec;69:61-69.
Daily Diet
11. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
Gene
Lifestyle
11
Food supplement (FS) blend of pomegranate, green
tea, broccoli and turmeric,
Adapted from : A double-blind, placebo-controlled randomised trial evaluating the effect of
a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer--
the U.K. NCRN Pomi-T study. Thomas R, Prostate Cancer Prostatic Dis. 2014 Jun;17(2):180-6.
12. What causes prostate cancer ?
About Nature, Nurture, and Prostate Cancer Risk
12
2,705 non-metastatic PCa from Health Professionals Follow-Up Study diagnosed observed
from 1990 to 2008; 548 deaths, 20% of which were a result of PCa.
categories of walking duration and pace after prostate cancer diagnosis. An easy pace is less than 2 mile per hour
(MPH), a normal pace is 2 to 2.9 MPH, and a brisk pace is 3 MPH. Adapted from SA. Kenfield et al., J Clin Oncol 29:726-732. 2011
All Cause Mortality PCa Mortality
-54%
It is urgent to produce, validate, and activate
lifestyle recommendation for patients with PCa
and create a support network.
13. Will adherence to diet and physical activity
really impact outcomes ?
13
“Adhering to cancer prevention guidelines for diet
and physical activity is consistently associated with
lower risks of overall cancer incidence and mortality,
including for some site-specific cancers.”
Cancer Epidemiol Biomarkers Prev; 25(7); 1018–28.
2016 AACR.
14. Paving the future for better prevention strategies
Conclusions
1. The “Magic” pill, or food supplement doesn’t exist.
2. We must secure that every man concerned about
PCa or treated for it:
1. Receives adequate counselling about genetic and other
risk factors
2. Receives adequate counselling on lifestyle adjustment
(including diet, food supplement and physical activity)
and have adequate access to the infrastructure or
health professional to activate these changes.
14