Judit Vasas1, Angéla Meszes MD1, Gyula Tálosi MD2, Katalin Rácz MD2,
Lajos KeményMD1, Zsanett Csoma MD1
1Department of Dermatology and Allergology, University of Szeged, Hungary 2Department of Paediatrics, University of Szeged, Hungary
This document summarizes two case reports of rare adenocarcinoma of the ceruminous glands that originated in the external auditory canal. In both cases, the tumors had grown into the middle ear and brain. One patient underwent surgery followed by adjuvant treatment for locally advanced disease. The other patient with advanced disease received only palliative therapy. Adenocarcinoma of the ceruminous glands is typically diagnosed at a late stage with local invasion that makes radical surgery difficult. These cases highlight the tumors' ability to primarily involve the intracranial space and subsequently spread to the middle ear.
How might we prevent occipital pressure ulcers in pediatric patients in an ic...Prashant Soni
This document provides an overview of the biodesign process and discusses developing a solution to prevent pressure ulcers in pediatric patients. It begins with outlining the biodesign process of identifying needs, ideating solutions, and developing prototypes. It then examines the need to prevent occipital pressure ulcers in pediatric intensive care patients, noting their high incidence rates. Current solutions are analyzed, finding that most adult-focused solutions fail for pediatric anatomy. The document brainstorms potential design approaches and showcases early prototypes to address the need.
This document discusses the challenges of pediatric wound care. It notes that wounds are a significant issue for children, especially those in critical care, and that most pediatric wounds are caused by medical devices rather than conventional pressure ulcers. It also highlights specific challenges like adapting products for smaller pediatric patients and managing fragile skin. The document advocates for a multidisciplinary team approach to wound care and describes programs developed at Cincinnati Children's Hospital and Texas Children's Hospital that have centralized wound care services and focus on prevention, standards, and research to address the unique needs in pediatric wound management.
This document discusses tools for assessing the risk level of skin injuries in incontinent patients, specifically looking at the Braden Scale and its use. The Braden Scale evaluates six indicators - sensory perception, moisture, activity, mobility, nutrition, and friction/shear - to determine a patient's risk level, which is classified as high, moderate, or low. It also compares risk levels assessed by the Braden Scale versus those for incontinence-associated dermatitis.
The document discusses pressure ulcers in patients undergoing extracorporeal membrane oxygenation (ECMO). It outlines the challenges in preventing pressure ulcers in these critically ill patients, whose skin is fragile and blood flow is compromised. It describes a quality improvement program at Texas Children's Hospital to reduce pressure ulcer rates through increased awareness, a skin care bundle including frequent repositioning and moisturizing, and specialized mattresses. The program achieved a reduction in pressure ulcer rates after implementation.
Care of aging_skin_spring 2014 abridgedShepard Joy
This document discusses aging changes to the skin and common skin conditions seen in older adults. It begins by outlining normal age-related changes including thinning and drying of the skin. Key skin conditions discussed include xerosis/pruritus, actinic keratosis, basal cell carcinoma, squamous cell carcinoma, and melanoma. Nursing assessments and interventions for dry skin and skin cancers are provided.
This document provides a history of pediatric cardiology and cardiac surgery in India and Andhra Pradesh. It discusses the early pioneers and developments in the field from the 1920s onwards, including the first open heart surgeries, catheter interventions, and advances in academics and training programs. It highlights the beginnings and growth of pediatric cardiology centers and programs across India as well as in Andhra Pradesh specifically. It also discusses current challenges and opportunities in pediatric heart care in India. In the end, it pays tribute to all those who have contributed to the growth of pediatric cardiology and cardiac surgery globally and in India.
This document summarizes the stages of gingival inflammation. It begins with initial inflammation seen as vascular changes like dilated capillaries. Early inflammation occurs within 1 week, shown microscopically as PMN infiltration. Established inflammation happens after 2-3 weeks of plaque accumulation and is characterized by B and T lymphocyte accumulation and plasma cell domination. Advanced inflammation involves bone loss and widespread tissue damage. The document provides histological details of the progression from healthy gingiva to advanced periodontitis.
This document summarizes two case reports of rare adenocarcinoma of the ceruminous glands that originated in the external auditory canal. In both cases, the tumors had grown into the middle ear and brain. One patient underwent surgery followed by adjuvant treatment for locally advanced disease. The other patient with advanced disease received only palliative therapy. Adenocarcinoma of the ceruminous glands is typically diagnosed at a late stage with local invasion that makes radical surgery difficult. These cases highlight the tumors' ability to primarily involve the intracranial space and subsequently spread to the middle ear.
How might we prevent occipital pressure ulcers in pediatric patients in an ic...Prashant Soni
This document provides an overview of the biodesign process and discusses developing a solution to prevent pressure ulcers in pediatric patients. It begins with outlining the biodesign process of identifying needs, ideating solutions, and developing prototypes. It then examines the need to prevent occipital pressure ulcers in pediatric intensive care patients, noting their high incidence rates. Current solutions are analyzed, finding that most adult-focused solutions fail for pediatric anatomy. The document brainstorms potential design approaches and showcases early prototypes to address the need.
This document discusses the challenges of pediatric wound care. It notes that wounds are a significant issue for children, especially those in critical care, and that most pediatric wounds are caused by medical devices rather than conventional pressure ulcers. It also highlights specific challenges like adapting products for smaller pediatric patients and managing fragile skin. The document advocates for a multidisciplinary team approach to wound care and describes programs developed at Cincinnati Children's Hospital and Texas Children's Hospital that have centralized wound care services and focus on prevention, standards, and research to address the unique needs in pediatric wound management.
This document discusses tools for assessing the risk level of skin injuries in incontinent patients, specifically looking at the Braden Scale and its use. The Braden Scale evaluates six indicators - sensory perception, moisture, activity, mobility, nutrition, and friction/shear - to determine a patient's risk level, which is classified as high, moderate, or low. It also compares risk levels assessed by the Braden Scale versus those for incontinence-associated dermatitis.
The document discusses pressure ulcers in patients undergoing extracorporeal membrane oxygenation (ECMO). It outlines the challenges in preventing pressure ulcers in these critically ill patients, whose skin is fragile and blood flow is compromised. It describes a quality improvement program at Texas Children's Hospital to reduce pressure ulcer rates through increased awareness, a skin care bundle including frequent repositioning and moisturizing, and specialized mattresses. The program achieved a reduction in pressure ulcer rates after implementation.
Care of aging_skin_spring 2014 abridgedShepard Joy
This document discusses aging changes to the skin and common skin conditions seen in older adults. It begins by outlining normal age-related changes including thinning and drying of the skin. Key skin conditions discussed include xerosis/pruritus, actinic keratosis, basal cell carcinoma, squamous cell carcinoma, and melanoma. Nursing assessments and interventions for dry skin and skin cancers are provided.
This document provides a history of pediatric cardiology and cardiac surgery in India and Andhra Pradesh. It discusses the early pioneers and developments in the field from the 1920s onwards, including the first open heart surgeries, catheter interventions, and advances in academics and training programs. It highlights the beginnings and growth of pediatric cardiology centers and programs across India as well as in Andhra Pradesh specifically. It also discusses current challenges and opportunities in pediatric heart care in India. In the end, it pays tribute to all those who have contributed to the growth of pediatric cardiology and cardiac surgery globally and in India.
This document summarizes the stages of gingival inflammation. It begins with initial inflammation seen as vascular changes like dilated capillaries. Early inflammation occurs within 1 week, shown microscopically as PMN infiltration. Established inflammation happens after 2-3 weeks of plaque accumulation and is characterized by B and T lymphocyte accumulation and plasma cell domination. Advanced inflammation involves bone loss and widespread tissue damage. The document provides histological details of the progression from healthy gingiva to advanced periodontitis.
The Mastoid Compartment of Middle Ear Cleft-A Clinic Pathological Study in Patients with Chronic Otitis Media-Mucosal Type by George MV in Experiments in Rhinology & Otolaryngology
https://crimsonpublishers.com/ero/fulltext/ERO.000525.php
This case report describes a rare case of true fibroma occurring on the palate of a 35-year-old male patient. The patient reported a lump on his palate that was interfering with chewing. Clinical examination revealed an irregular, grayish growth on the palate that was excised using diode laser. Histological examination showed features consistent with true fibroma, including sharp demarcation from surrounding tissue and a fibrous capsule. Immunohistochemical staining was negative for S-100, confirming it was not a neural tumor, and positive for fibrous tissue antigens. This supported the diagnosis of a true fibroma, which is a rare benign neoplasm of the oral cavity. The patient had no recurrence at 15-day
This document discusses several controversies in periodontics. It addresses debates around the classification of periodontal diseases, factors involved in periodontal pathogenesis like invasiveness of bacteria and the role of the periodontal epithelium. It also examines controversies in diagnosing periodontal diseases and determining an accurate prognosis. Additionally, it looks at debates around treatments like gingival curettage, tooth mobility and splinting, one stage full-mouth disinfection versus quadrant SRP, and whether results are comparable between non-surgical and surgical periodontal therapy. The document acknowledges that while knowledge has improved, some controversies remain due to limitations in present diagnostic methods and incomplete understanding of periodontal pathology.
This case report describes a 12-year-old boy with Down syndrome who presented with swelling of the right eyelid and was diagnosed with Luc's abscess, a rare complication of otitis media. Imaging showed abscess foci in the mastoid bone with extension to the right eyelid and cheek. The patient developed bilateral preseptal cellulitis despite antibiotic treatment. He underwent mastoidectomy and repair of a cerebrospinal fluid leak, which revealed widespread bone and tissue destruction. The patient recovered fully after surgery and additional antibiotic treatment. The report discusses the clinical features and management of Luc's abscess, noting its rare occurrence but potential for life-threatening complications if not treated promptly.
Periodontal disease results from a complex interplay between subgingival biofilm and the host immune-inflammatory response. While several bacteria are found in periodontal pockets, no single organism causes the disease. The pathogenesis involves the host response to the bacterial challenge, which can remain at a low, asymptomatic level or progress to tissue destruction if left unchecked. Understanding these disease processes is important for developing improved treatment strategies.
This case report describes a 62-year-old female patient who presented with a non-healing gingival lesion. Initial biopsy found non-specific inflammation and giant cells suggestive of pyogenic granuloma. Two years later when the lesion had increased in size, investigations revealed miliary nodules in the lungs and a granulomatous infection. Tuberculin test was weakly positive and culture from biopsy grew Mycobacterium tuberculosis. The patient was diagnosed with secondary oral tuberculosis from post-primary pulmonary tuberculosis and showed improvement with antitubercular treatment. The report discusses the rare occurrence of oral tuberculosis lesions and challenges in diagnosis.
Influence of systemic disorders on periodontal diseases is well established. However, of growing interest is the effect of periodontal diseases on numerous systemic diseases or conditions like cardiovascular disease, cerebrovascular disease, diabetes, pre-term low birth weight babies, preeclampsia, respiratory infections and others including osteoporosis, cancer, rheumatoid arthritis, erectile dysfunction, Alzheimer's disease, gastrointestinal disease, prostatitis, renal diseases, which has also been scientifically validated. This side of the oral-systemic link has been termed Periodontal Medicine and is potentially of great public health significance, as periodontal disease is largely preventable and in many instances readily treatable, hence, providing many new opportunities for preventing and improving prognosis of several systemic pathologic conditions. in this power point Dr Harshavardhan Patwal , highlights the importance of prevention and treatment of periodontal diseases as an essential part of preventive medicine to circumvent its deleterious effects on general health.
Of partial defects of the dental rows of dynamic study of the state of the mu...SubmissionResearchpa
Despite the rapid development of dentistry and advances in the prevention of diseases of the maxillofacial region, implantology, and the treatment of dental diseases, the number of patients who need prosthetics with removable orthopedic structures of dentures remains high, and only increases with age, due to the increasing rate of aging. society of the planet (M.Yu. Ogorodnikov, 2007; V.I.Shemonaev, 2012; E.S. Kalivradzhiyan, 2013; E.A.Zholudev, 2014; CE. Bragin, 2014; L.D. Veisheim, 2014). Among the reasons for the high demand for orthopedic treatment with removable dentures, the leading position is still held by insufficient sanitation of the oral cavity, untimely access of patients to the dentist. In addition, an important role is played by the problem of imperfection of materials and technologies used for the manufacture of dentures, leading to a deterioration in the condition of the dentition by A.Kh. Zhumaev 2020. Of partial defects of the dental rows of dynamic study of the state of the mucosa of the oral cavity in the new conditions of functioning. International Journal on Integrated Education. 3, 12 (Dec. 2020), 61-63. DOI:https://doi.org/10.31149/ijie.v3i12.913 https://journals.researchparks.org/index.php/IJIE/article/view/913/861 https://journals.researchparks.org/index.php/IJIE/article/view/913
A 12-year-old female presented with swelling and pain in the right lower back tooth region. Radiographs revealed a well-defined radiolucency surrounding the right mandibular first, second, and third molars. The lesion was enucleated along with extraction of the involved teeth. Histopathological examination found a cystic cavity lined by non-keratinized epithelium, consistent with a radicular cyst. Follow-up after 1 month showed complete healing. This case report describes the presentation, management, and outcomes of a large multi-tooth radicular cyst in the mandible of a pediatric patient.
36.Kesharwani P, Hussain SA, Sharma N, Karpathak S, Bhanot R, Kothari S, Tiwari RVC. Massive radicular cyst involving multiple teeth in pediatric mandible- A case report. J Family Med Prim Care. 2020 Feb;9(2):1253-1256. doi: 10.4103/jfmpc.jfmpc_1059_19. eCollection 2020 Feb. PubMed PMID: 32318508; PubMed Central PMCID: PMC7113959.
A case of childhood Burkitt's lymphoma with gingival swelling as the first sy...komalicarol
This case report describes a 4-year-old child who presented with gingival swelling as the initial symptom of Burkitt's lymphoma. The child was eventually diagnosed with stage IV Burkitt's lymphoma/leukemia based on bone marrow and genetic testing. After initial chemotherapy, the gingival swelling and right cheek swelling recurred, indicating disease recurrence. The child received further chemotherapy but ultimately passed away half a year later. This case highlights that gingival swelling can be an early oral symptom of systemic disease like Burkitt's lymphoma. Dentists and oral physicians play an important role in identifying signs of systemic conditions through oral examinations.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Tuberculosis: A Rare Cause of Linear Labial Ulcerationkomalicarol
Oral location of tuberculosis is rare. It admits a clinical polymorphism and poses above all a problem of diagnosis. We report a
case of labial tuberculosis in a 16-year-old patient with underlying
lymph node localization.
This case report describes a 9-year-old female patient with fibrous dysplasia of the maxilla and a port wine stain on her face. Clinical examination and radiographic imaging showed abnormal bone growth replacing the maxilla. A biopsy confirmed the diagnosis of fibrous dysplasia. The patient underwent surgical recontouring of the maxilla and was happy with the results at her 2-week follow up appointment. Fibrous dysplasia is a benign condition where abnormal bone growth replaces normal bone, usually becoming inactive in adulthood, though some cases like this one may continue progressing during childhood growth.
Atypical ameloblastoma – an enigma in diagnosis review of literature and rep...Quách Bảo Toàn
This case report describes an atypical ameloblastoma presenting diagnostic challenges. Histologically, the lesion showed features of both benign and malignant ameloblastoma. While areas displayed typical ameloblastoma characteristics, other areas showed epithelial dedifferentiation like cellular pleomorphism and atypical mitoses. However, these atypical features were not sufficient to classify it as ameloblastic carcinoma. The case was therefore diagnosed as an atypical ameloblastoma and close follow up was recommended due to its ambiguous nature between benign and malignant pathology. The report also briefly reviews the classification and literature on odontogenic malignancies.
Eosinophilic Ulcer of the Oral Cavity, Approach, and Differential Diagnosissemualkaira
Benign ulcerations of the oral mucosa may have a similar appearance to malignant lesions [1, 2]. There are several conditions, both local and systemic, that can manifest as oral ulcers, and that can correspond, on many occasions, to both infectious and autoimmune causes. Probable etiology can often be determined by a complete medical history and a careful physical examination. However, on several occasions, an exhaustive diagnostic study will be necessary, counting on a range of diagnostic suspicions
Dentigerous cyst in maxilla in a young girlMausumi Iqbal
This document describes a case report of a rare dentigerous cyst in an 8-year-old girl arising from an unerupted maxillary premolar that had invaded the right maxillary sinus. Clinically, the patient presented with swelling in the right upper jaw. Radiographs revealed a partially formed tooth surrounded by a radiolucent area. The cyst was surgically removed via enucleation along with the displaced tooth. Histopathological examination confirmed the diagnosis of a dentigerous cyst.
This study compared the clinical, radiographic, histopathologic, and histobacteriologic features of true and bay apical cysts. The study found no significant differences between true and bay cysts for any of the parameters evaluated. Both cyst types always exhibited intraradicular infection and sometimes extraradicular infection as well. The findings question the need to differentiate between true and bay cysts and do not support the assumption that true cysts are self-sustaining entities not associated with infection.
EWMA 2014 - EP502 A LABORATORY EVALUATION OF THE BLOOD ABSORPTION PROPERTIES ...EWMA
This study compared the blood absorption properties of 5 surgical dressings (A-E). An in vitro experiment added bovine blood to dressings at a constant rate, measuring absorption capacity and dispersion. Dressing A (Mepilex Border Post-Op) absorbed the largest volume of blood before reaching the dressing edges or leaking, with good dispersion throughout. The results indicate Dressing A will require fewer dressing changes and better protect wounds from contamination compared to the other dressings tested.
The Mastoid Compartment of Middle Ear Cleft-A Clinic Pathological Study in Patients with Chronic Otitis Media-Mucosal Type by George MV in Experiments in Rhinology & Otolaryngology
https://crimsonpublishers.com/ero/fulltext/ERO.000525.php
This case report describes a rare case of true fibroma occurring on the palate of a 35-year-old male patient. The patient reported a lump on his palate that was interfering with chewing. Clinical examination revealed an irregular, grayish growth on the palate that was excised using diode laser. Histological examination showed features consistent with true fibroma, including sharp demarcation from surrounding tissue and a fibrous capsule. Immunohistochemical staining was negative for S-100, confirming it was not a neural tumor, and positive for fibrous tissue antigens. This supported the diagnosis of a true fibroma, which is a rare benign neoplasm of the oral cavity. The patient had no recurrence at 15-day
This document discusses several controversies in periodontics. It addresses debates around the classification of periodontal diseases, factors involved in periodontal pathogenesis like invasiveness of bacteria and the role of the periodontal epithelium. It also examines controversies in diagnosing periodontal diseases and determining an accurate prognosis. Additionally, it looks at debates around treatments like gingival curettage, tooth mobility and splinting, one stage full-mouth disinfection versus quadrant SRP, and whether results are comparable between non-surgical and surgical periodontal therapy. The document acknowledges that while knowledge has improved, some controversies remain due to limitations in present diagnostic methods and incomplete understanding of periodontal pathology.
This case report describes a 12-year-old boy with Down syndrome who presented with swelling of the right eyelid and was diagnosed with Luc's abscess, a rare complication of otitis media. Imaging showed abscess foci in the mastoid bone with extension to the right eyelid and cheek. The patient developed bilateral preseptal cellulitis despite antibiotic treatment. He underwent mastoidectomy and repair of a cerebrospinal fluid leak, which revealed widespread bone and tissue destruction. The patient recovered fully after surgery and additional antibiotic treatment. The report discusses the clinical features and management of Luc's abscess, noting its rare occurrence but potential for life-threatening complications if not treated promptly.
Periodontal disease results from a complex interplay between subgingival biofilm and the host immune-inflammatory response. While several bacteria are found in periodontal pockets, no single organism causes the disease. The pathogenesis involves the host response to the bacterial challenge, which can remain at a low, asymptomatic level or progress to tissue destruction if left unchecked. Understanding these disease processes is important for developing improved treatment strategies.
This case report describes a 62-year-old female patient who presented with a non-healing gingival lesion. Initial biopsy found non-specific inflammation and giant cells suggestive of pyogenic granuloma. Two years later when the lesion had increased in size, investigations revealed miliary nodules in the lungs and a granulomatous infection. Tuberculin test was weakly positive and culture from biopsy grew Mycobacterium tuberculosis. The patient was diagnosed with secondary oral tuberculosis from post-primary pulmonary tuberculosis and showed improvement with antitubercular treatment. The report discusses the rare occurrence of oral tuberculosis lesions and challenges in diagnosis.
Influence of systemic disorders on periodontal diseases is well established. However, of growing interest is the effect of periodontal diseases on numerous systemic diseases or conditions like cardiovascular disease, cerebrovascular disease, diabetes, pre-term low birth weight babies, preeclampsia, respiratory infections and others including osteoporosis, cancer, rheumatoid arthritis, erectile dysfunction, Alzheimer's disease, gastrointestinal disease, prostatitis, renal diseases, which has also been scientifically validated. This side of the oral-systemic link has been termed Periodontal Medicine and is potentially of great public health significance, as periodontal disease is largely preventable and in many instances readily treatable, hence, providing many new opportunities for preventing and improving prognosis of several systemic pathologic conditions. in this power point Dr Harshavardhan Patwal , highlights the importance of prevention and treatment of periodontal diseases as an essential part of preventive medicine to circumvent its deleterious effects on general health.
Of partial defects of the dental rows of dynamic study of the state of the mu...SubmissionResearchpa
Despite the rapid development of dentistry and advances in the prevention of diseases of the maxillofacial region, implantology, and the treatment of dental diseases, the number of patients who need prosthetics with removable orthopedic structures of dentures remains high, and only increases with age, due to the increasing rate of aging. society of the planet (M.Yu. Ogorodnikov, 2007; V.I.Shemonaev, 2012; E.S. Kalivradzhiyan, 2013; E.A.Zholudev, 2014; CE. Bragin, 2014; L.D. Veisheim, 2014). Among the reasons for the high demand for orthopedic treatment with removable dentures, the leading position is still held by insufficient sanitation of the oral cavity, untimely access of patients to the dentist. In addition, an important role is played by the problem of imperfection of materials and technologies used for the manufacture of dentures, leading to a deterioration in the condition of the dentition by A.Kh. Zhumaev 2020. Of partial defects of the dental rows of dynamic study of the state of the mucosa of the oral cavity in the new conditions of functioning. International Journal on Integrated Education. 3, 12 (Dec. 2020), 61-63. DOI:https://doi.org/10.31149/ijie.v3i12.913 https://journals.researchparks.org/index.php/IJIE/article/view/913/861 https://journals.researchparks.org/index.php/IJIE/article/view/913
A 12-year-old female presented with swelling and pain in the right lower back tooth region. Radiographs revealed a well-defined radiolucency surrounding the right mandibular first, second, and third molars. The lesion was enucleated along with extraction of the involved teeth. Histopathological examination found a cystic cavity lined by non-keratinized epithelium, consistent with a radicular cyst. Follow-up after 1 month showed complete healing. This case report describes the presentation, management, and outcomes of a large multi-tooth radicular cyst in the mandible of a pediatric patient.
36.Kesharwani P, Hussain SA, Sharma N, Karpathak S, Bhanot R, Kothari S, Tiwari RVC. Massive radicular cyst involving multiple teeth in pediatric mandible- A case report. J Family Med Prim Care. 2020 Feb;9(2):1253-1256. doi: 10.4103/jfmpc.jfmpc_1059_19. eCollection 2020 Feb. PubMed PMID: 32318508; PubMed Central PMCID: PMC7113959.
A case of childhood Burkitt's lymphoma with gingival swelling as the first sy...komalicarol
This case report describes a 4-year-old child who presented with gingival swelling as the initial symptom of Burkitt's lymphoma. The child was eventually diagnosed with stage IV Burkitt's lymphoma/leukemia based on bone marrow and genetic testing. After initial chemotherapy, the gingival swelling and right cheek swelling recurred, indicating disease recurrence. The child received further chemotherapy but ultimately passed away half a year later. This case highlights that gingival swelling can be an early oral symptom of systemic disease like Burkitt's lymphoma. Dentists and oral physicians play an important role in identifying signs of systemic conditions through oral examinations.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Tuberculosis: A Rare Cause of Linear Labial Ulcerationkomalicarol
Oral location of tuberculosis is rare. It admits a clinical polymorphism and poses above all a problem of diagnosis. We report a
case of labial tuberculosis in a 16-year-old patient with underlying
lymph node localization.
This case report describes a 9-year-old female patient with fibrous dysplasia of the maxilla and a port wine stain on her face. Clinical examination and radiographic imaging showed abnormal bone growth replacing the maxilla. A biopsy confirmed the diagnosis of fibrous dysplasia. The patient underwent surgical recontouring of the maxilla and was happy with the results at her 2-week follow up appointment. Fibrous dysplasia is a benign condition where abnormal bone growth replaces normal bone, usually becoming inactive in adulthood, though some cases like this one may continue progressing during childhood growth.
Atypical ameloblastoma – an enigma in diagnosis review of literature and rep...Quách Bảo Toàn
This case report describes an atypical ameloblastoma presenting diagnostic challenges. Histologically, the lesion showed features of both benign and malignant ameloblastoma. While areas displayed typical ameloblastoma characteristics, other areas showed epithelial dedifferentiation like cellular pleomorphism and atypical mitoses. However, these atypical features were not sufficient to classify it as ameloblastic carcinoma. The case was therefore diagnosed as an atypical ameloblastoma and close follow up was recommended due to its ambiguous nature between benign and malignant pathology. The report also briefly reviews the classification and literature on odontogenic malignancies.
Eosinophilic Ulcer of the Oral Cavity, Approach, and Differential Diagnosissemualkaira
Benign ulcerations of the oral mucosa may have a similar appearance to malignant lesions [1, 2]. There are several conditions, both local and systemic, that can manifest as oral ulcers, and that can correspond, on many occasions, to both infectious and autoimmune causes. Probable etiology can often be determined by a complete medical history and a careful physical examination. However, on several occasions, an exhaustive diagnostic study will be necessary, counting on a range of diagnostic suspicions
Dentigerous cyst in maxilla in a young girlMausumi Iqbal
This document describes a case report of a rare dentigerous cyst in an 8-year-old girl arising from an unerupted maxillary premolar that had invaded the right maxillary sinus. Clinically, the patient presented with swelling in the right upper jaw. Radiographs revealed a partially formed tooth surrounded by a radiolucent area. The cyst was surgically removed via enucleation along with the displaced tooth. Histopathological examination confirmed the diagnosis of a dentigerous cyst.
This study compared the clinical, radiographic, histopathologic, and histobacteriologic features of true and bay apical cysts. The study found no significant differences between true and bay cysts for any of the parameters evaluated. Both cyst types always exhibited intraradicular infection and sometimes extraradicular infection as well. The findings question the need to differentiate between true and bay cysts and do not support the assumption that true cysts are self-sustaining entities not associated with infection.
Similar to EWMA 2013 - Ep531 - Treatment of pressure ulcer in childhood (20)
EWMA 2014 - EP502 A LABORATORY EVALUATION OF THE BLOOD ABSORPTION PROPERTIES ...EWMA
This study compared the blood absorption properties of 5 surgical dressings (A-E). An in vitro experiment added bovine blood to dressings at a constant rate, measuring absorption capacity and dispersion. Dressing A (Mepilex Border Post-Op) absorbed the largest volume of blood before reaching the dressing edges or leaking, with good dispersion throughout. The results indicate Dressing A will require fewer dressing changes and better protect wounds from contamination compared to the other dressings tested.
EWMA 2014 - EP499 MANAGEMENT OF AN INFECTED DIABETIC FOOT WITH SPECIALIZED DR...EWMA
This document presents two case studies of patients with diabetic foot infections. Both patients, aged 29 and 52, underwent surgical debridement and partial amputation of the infected toes. Controlling the infection and exudate levels in the wounds proved difficult, requiring the use of various antimicrobial dressings over a 4-month period. Through a combination of wound bed preparation, surgical debridement, and specialized dressings, the treatment was ultimately successful in controlling the infections and promoting wound healing.
EWMA 2014 - EP498 USE OF NEGATIVE PRESSURE THERAPY IN CONJUNCTION WITH A PROT...EWMA
Este documento describe el caso de un paciente diabético con una ulcera grave en el pie que fue tratada con éxito mediante la aplicación combinada de terapia de presión negativa y una matriz moduladora de proteasas. El tratamiento promovió el rápido crecimiento de tejido de granulación, permitiendo cubrir las estructuras óseas expuestas y prevenir infecciones. La matriz aceleró la epitelización y contracción de la herida, logrando su cierre total en 60 días. El uso combinado de estas tecnologías es una altern
EWMA 2014 - EP496 CONTEMPORARY SILVER DRESSINGS IN THE TREATMENT OF INFECTED ...EWMA
Ivan Poromanski and Yordan Milev evaluated the use of silver-coated dressings in managing cavitary wounds after bone resection for infected neuropathic diabetic foot. In three cases of patients with osteomyelitis of the foot, residual bone defects were filled with either silver-coated alginate/foam dressings or silver alginate filler. The dressings were changed every 48-72 hours with offloading. Systemic antibiotics were used for no more than 10 days until soft tissue infection subsided. The cavitary wounds healed within 42 days and plantar ulcers healed within 14-21 days, which was shorter than usual treatment times. The higher price of silver dressings was offset by fewer dressing changes
EWMA 2014 - EP495 TOTAL CONTACT CASTING – A SOUTH AFRICAN APPROACH TOWARDS OF...EWMA
This study evaluated two total contact casting (TCC) systems for offloading diabetic foot ulcers and stabilizing Charcot feet in South Africa. System B, which used a washable, water resistant inner lining, demonstrated better patient adherence and aeration compared to System A. Both systems effectively reduced plantar pressures and healed wounds within 36 days on average. The study concluded that TCC is the gold standard for offloading but more training is needed for healthcare professionals to incorporate it widely in practice.
Este estudio buscó detectar factores de riesgo de pie diabético en personas con diabetes mediante consultas de enfermería. Se evaluó a 56 pacientes con diabetes tipo 1 o 2 sin lesiones en los pies. Más del 30% presentaron alto riesgo de desarrollar pie diabético debido a factores como baja escolaridad, falta de educación sobre el cuidado de los pies, antecedentes de úlceras y amputaciones, y calzado y corte de uñas inadecuados. El estudio concluye que es necesario fortalecer
EWMA 2014 - EP490 THE CHARACTERISTICS OF WOUND PAIN ASSOCIATED WITH DIABETES-...EWMA
This study examined the prevalence and characteristics of wound pain in diabetes-related foot ulcers. It found that over 50% of patients reported experiencing wound pain based on formal pain assessment tools, even though some did not report pain to their podiatrist. Pain was described as tender, brief, or intermittent. Both neuropathic and neuroischaemic ulcers had low reported pain intensity and little effect on quality of life. The study concludes wound pain may be underassessed clinically and more research is needed to understand differences in pain between ulcer types.
EWMA 2014 - EP485 EVALUATION OF MR ANGIOGRAPHY RESULTS IN DIABETIC FOOT PATIENTSEWMA
This document evaluates the results of MR angiography (MRA) in diabetic foot patients to detect peripheral arterial disease (PAD). A cross-sectional study of 100 diabetic patients with clinical symptoms of PAD found that while 32% had abnormal ankle brachial index measurements, 63.4% showed abnormalities on MRA. The conclusion is that while ankle brachial index is trustworthy for detecting severe ischemia, MRA should be used for other degrees of ischemia as it can detect more cases of abnormality than ankle brachial index alone. More patients need to be studied to determine what types of abnormalities found on MRA are associated with outcomes like healing or amputation.
EWMA 2014 - EP483 THE EFFECTS OF DIABETIC FOOT ULCER (DFU) WOUND FLUID PH ON ...EWMA
This study examined the effect of diabetic foot ulcer (DFU) wound fluid pH on the presence of bacteria. Wound fluid was collected from 55 patients with DFUs and tested for pH and bacteria. A variety of bacteria were found, most commonly Staphylococcus and Streptococcus species. Higher pH wound fluid (>7.5) was associated with some bacterial species while others were found more often at neutral pH (<7.5). DFUs with clinical signs of infection had significantly higher pH than non-infected wounds. The results suggest that wound fluid pH, especially values over 7.2, could help identify silent infections and inform treatment decisions.
EWMA 2014 - EP482 COMPARISON OF ANGIOGRAPHIC FINDINGS BETWEEN PATIENTS WITH N...EWMA
This document compares angiographic findings between patients with non-healing diabetic foot ulcers (DFUs) with and without Charcot foot (CF). It found that patients with CF and DFUs had less severe peripheral arterial disease (PAD) based on angiographic findings compared to DFU patients without CF, however revascularization rates were equal between the two groups. The study assessed 29 CF patients and 48 non-CF patients with DFUs who underwent lower limb angiography. It found patients without CF had significantly more frequent presence of severe PAD (Graziani class 4 and higher) versus the CF group.
EWMA 2014 - EP477 EVALUATION OF FOOT SELF CARE KNOWLEDGE AND PRACTICES IN SAU...EWMA
This study assessed foot self-care knowledge and practices in 350 Saudi patients with diabetes referred to a specialized diabetes care center. While 42.6% had excellent knowledge of how diabetes affects foot health, only 17.7% demonstrated good ability to identify and apply appropriate foot self-care practices. Most patients acquired knowledge through media rather than primary health care clinics. The quality of knowledge from primary care clinics did not translate to better ability to practice self-care compared to other sources of knowledge. The study concludes current foot self-care education and knowledge is unsatisfactory and calls for a national diabetes control program delivering unified, evidence-based education through healthcare providers and media to prevent limb loss.
EWMA 2014 - EP476 DIABETIC FOOT ULCER HEALING IN RELATIONSHIP WITH INITIAL TR...EWMA
This study examined the relationship between initial transcutaneous oxygen pressure (TcPO2) measurements and healing of diabetic foot ulcers over 6 and 12 months. TcPO2 is a non-invasive method to detect peripheral arterial disease. The study found that 76% of patients had a TcPO2 of ≤30mmHg and 81% had a TcPO2 of ≤40mmHg, indicating peripheral arterial disease. Healing rates were higher in patients with a TcPO2 >30mmHg or >40mmHg. Using a TcPO2 threshold of 40mmHg rather than 30mmHg showed higher sensitivity and negative predictive value for predicting healing. The study concludes that a TcPO2 threshold
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We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
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Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
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ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
EWMA 2013 - Ep531 - Treatment of pressure ulcer in childhood
1. Judit Vasas1, Angéla Meszes MD1, Gyula Tálosi MD2, Katalin Rácz MD2,
Lajos KeményMD1, Zsanett Csoma MD1
1Department of Dermatology and Allergology, University of Szeged, Hungary
2Department of Paediatrics, University of Szeged, Hungary
2. high prevalence of pressure ulcers (PUs):
27 % in paediatric intensive care units (PICUs)
23 % in neonatal intensive care units (NICUs)
acutely ill, sedated, paralysed or immobilized neonates
and children are at risk
occipital region, ear, nose or knees
medical devices and equipment can also cause PUs at
any sites
Braden Q Scale for risk of PUs in paediatric population
hydrogels, hydrocolloids, foam and film dressings are
advised
3. to review pressure ulcers
between January 2012 and January 2013
tertiary NICU and PICU
Patients were studied for:
age
sex
area of involvement
stages of decubitus (NUPAP)
treatment
4. Patients
Gender
(M/F)
Gestational
age (week)
Birth weigth
(g)
Lesion Localisation Treatment
1. F 39 3980 erythema (St. I.)
occipital
region
herb
containing
gel
2 M 40 3440
erythema (St. I).
occipital
region
herb
containing
gel
3. M 37 3500
haemorrhagious
erosion with crust
(St. II.)
occipital
region
hydrogels,
epithelizing
ointment
4. F 38 2480
haemorrhagious
ulcers with crust
(St. II.)
occipital
region
hydrogels,
epithelizing
ointment
5. F 26 700
superficial ulcers
with crusts (St. II)
left nasal
orifice
boracic acid
containing
ointment
211 neonates in NICU
5 neonates with pressure ulcers - prevalence of 2,36%
4/5 in the occipital region
1/5 in the left nasal orifice due to nasal CPAP cannule
5.
6. Patients
in PICU
Gender
M/F
Age Lesion Localisation Treatment
1. M 3 year superficial ulcers with crusts (St. II) occipital region hydrogels, hydrocolloids
2. M 2 years two necrotic ulcers (St. III.) occipital region
hydroactive wound dressings
hydrogels, alginates, hydrocolloids,
silicon and foam dressings
3 M 1 year
two necrotic ulcers with crusts (St. II-
III.)
occipital region
hydrogels, alginates, foam
dressings, hydrocolloids
4. M 20 months 4 rounded necrotoic ulcers (St. II, III.) occipital region hydrogels hydrocolloids
5. F 10 years
superficial ulcer (St. II.), ulcer with
crusts (ST. III.)
sacrum, occipital
region
hydrogels, foam dressings
6. M 7 years
deep, necrotic ulcer, bone at the
bottom (St. IV.)
sacrum alginate
7. F 14 years bulla 3 cm in diameter (St. II.) right heel hydrogels, foam dressing
8 M 11 months superficial ulcer with crust (St. II.) occipital region hydrogels, foam dressings
9. M 4 months haemorrhage, erythema (St.I.) occipital region herb containing gel
10. F 18 months superficial ulcer with crust (St. II.) occipital region hydrogels, epithelizing ointment
11 M 15 years
deep, necrotic ulcer with bone at the
wound base (St, IV.)
sacrum alginate dressings
12. F 4 months superficial ulcers with crusts (St. II.) occipital region hydrogels, epithelizing ointment
13 M 10 years eryhema (St. I.)
both lateral
malleus
herb containing gel
14 F 11 years
haemorrhagious, necrotic based
ulcers (St. III.)
occipital region,
trunk, sacrum
hydrogels, hydrocolloids, silver
alginate,
15 M 12 years
haemorrhage, bulla, superficial ulcer
(St. II.)
left heel hydrogels, povidone iodine cream
7. 385 neonates in PICU
15 children with
pressure ulcers
prevalence 3,89%
8.
9.
10. Prevention is inevitable
reposition of patients
check and reposition of medical equipments
weight-relieving gel pillows and foam
mattresses
Minimizing risk with nutritional considerations
Paucity of evidence-based local therapy
Futher researches are needed with dressings