The endocrine system consists of glands that secrete hormones directly into the bloodstream to regulate various bodily functions such as growth, metabolism, reproduction, and the stress response. The major endocrine glands include the pituitary, thyroid, parathyroids, adrenals, pancreas, and gonads. The endocrine system works through chemical messengers called hormones to help maintain homeostasis, support growth and development, and coordinate cellular and organ functions throughout the body.