Elsevier’s Healthcare
Knowledge Graph
Alex DeJong, Radmila Bord, Will Dowling, Rinke Hoekstra, Ryan Moquin, Charlie O, Mevan
Samarasinghe, Paul Snyder, Craig Stanley, Anna Tordai, Michael Trefry, and Paul Groth.
@pgroth | @elsevierlabs
October 10, 2018
The Case for Enterprise Linked
Data Standards
“A global information analytics business”
2
Knowledge Graphs at Elsevier
3
A Health Care Knowledge Graph
4
What types of questions do clinicians ask?
Spans Entity Types
- Drugs
- Diagnosis
- Symptoms
- Phenotypes
- Diseases
- …
H-Graph: The Elsevier Health Knowledge Graph
400K+ medical concepts with relations and extensive
mappings to industry vocabularies and multi-language support
4.9M+ semantic relations extracted from medical
literature using NLP and convolutional neural networks
Deep and expressive graph model extends relations with
qualitative and quantitative context
Graph-based knowledge representations power
advanced clinical decision support applications
Deeper Data Lies in Products
Deeper Data Lies in Products
But how do we get at it with
minimal impact to current
workflows?
Use Linked Data to Integrate
8
Linked Data Principles are under specified
• What syntax do you provide and as a
consumer can you expect?
• What names spaces do you use?
• How do you link to single sign-on?
• What links should you set?
9
Elsevier Linked Data Standards
10
Elsevier Linked Data Standards
11
Elsevier Linked Data Standards
12
Videos and Documents
Patient Education
Drug Database
Gold Standard
Care Plans
Order Sets
Clinical Trial Data
MACRO
Radiology Images
StatDX
Pathology Images
ExpertPath
Books and Journals
ScienceDirect
ICD-10
RxNorm LOINC
SNOMED
MeSH
H-Graph Core
Graph Database
External Vocabularies
H-Graph
Core
Clinical Guidelines
LD API
LD API
LDAPI
LDAPI
LDAPI
LD API
LD API
LDAPI
LD API
LD API
LD API
Patient Journey
Patient
Intake
Suspected
Diagnosis
Diagnostic
Test
Confirmed
Diagnosis
Treatment
Plan
Treatment
Delivery
Discharge &
Ongoing Care
Elsevier
Patient Journey
Products and ACDS
Differential Diagnosis
Alerts
Image Analysis
Pathways
Order Sets
Care Plans
Patient Engagement
Skills & eLearning
Clinical Overviews
ClinicalKey Reference
Gold Standard
H-Graph: The Elsevier Health Knowledge Graph
H-Graph Core connects Elsevier products, data, and healthcare content to power ACDS
Pre-Visit
Symptom
Checkers
(e.g., Arezzo)
Patient-Centered Apps
(e.g., chronic disease
management
for diabetes)
Result: a unified but distributed knowledge graph
14
Lesson: Namespace control is key
15
Lesson: Developer UX
16
Thank you
Paul Groth | @pgroth
@elsevierlabs

Elsevier’s Healthcare Knowledge Graph

  • 1.
    Elsevier’s Healthcare Knowledge Graph AlexDeJong, Radmila Bord, Will Dowling, Rinke Hoekstra, Ryan Moquin, Charlie O, Mevan Samarasinghe, Paul Snyder, Craig Stanley, Anna Tordai, Michael Trefry, and Paul Groth. @pgroth | @elsevierlabs October 10, 2018 The Case for Enterprise Linked Data Standards
  • 2.
    “A global informationanalytics business” 2
  • 3.
  • 4.
    A Health CareKnowledge Graph 4 What types of questions do clinicians ask? Spans Entity Types - Drugs - Diagnosis - Symptoms - Phenotypes - Diseases - …
  • 5.
    H-Graph: The ElsevierHealth Knowledge Graph 400K+ medical concepts with relations and extensive mappings to industry vocabularies and multi-language support 4.9M+ semantic relations extracted from medical literature using NLP and convolutional neural networks Deep and expressive graph model extends relations with qualitative and quantitative context Graph-based knowledge representations power advanced clinical decision support applications
  • 6.
    Deeper Data Liesin Products
  • 7.
    Deeper Data Liesin Products But how do we get at it with minimal impact to current workflows?
  • 8.
    Use Linked Datato Integrate 8
  • 9.
    Linked Data Principlesare under specified • What syntax do you provide and as a consumer can you expect? • What names spaces do you use? • How do you link to single sign-on? • What links should you set? 9
  • 10.
  • 11.
  • 12.
  • 13.
    Videos and Documents PatientEducation Drug Database Gold Standard Care Plans Order Sets Clinical Trial Data MACRO Radiology Images StatDX Pathology Images ExpertPath Books and Journals ScienceDirect ICD-10 RxNorm LOINC SNOMED MeSH H-Graph Core Graph Database External Vocabularies H-Graph Core Clinical Guidelines LD API LD API LDAPI LDAPI LDAPI LD API LD API LDAPI LD API LD API LD API Patient Journey Patient Intake Suspected Diagnosis Diagnostic Test Confirmed Diagnosis Treatment Plan Treatment Delivery Discharge & Ongoing Care Elsevier Patient Journey Products and ACDS Differential Diagnosis Alerts Image Analysis Pathways Order Sets Care Plans Patient Engagement Skills & eLearning Clinical Overviews ClinicalKey Reference Gold Standard H-Graph: The Elsevier Health Knowledge Graph H-Graph Core connects Elsevier products, data, and healthcare content to power ACDS Pre-Visit Symptom Checkers (e.g., Arezzo) Patient-Centered Apps (e.g., chronic disease management for diabetes)
  • 14.
    Result: a unifiedbut distributed knowledge graph 14
  • 15.
  • 16.
  • 17.
    Thank you Paul Groth| @pgroth @elsevierlabs

Editor's Notes

  • #7 Data is curated, maintained, and processed on different platforms
  • #8 Data is curated, maintained, and processed on different platforms
  • #16 Lesson learned
  • #17 Lesson learned