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EHR – The Killer App?

                                               HINZ
                           Bringing the Electronic Health Record to Life
                                           21 June 2012
W. Ed Hammond. Ph.D., FACMI, FAIMBE, FIMIA, FHL7
Director, Duke Center for Health Informatics
Director, Applied Informatics Research, DHTS
Associate Director, Biomedical Informatics Core, DTMI
Professor, Department of Community and Family Medicine
Professor Emeritus, Department of Biomedical Engineering
Adjunct Professor, Fuqua School of Business
Duke University
Chair Emeritus, HL7




                                                                           2
What is a killer app?

An application that
accelerates the adoption
and ubiquitous use of the
application.

                            3
Killer apps
•   Personal computer
•   World-wide web
•   Wireless networks
•   Google, Facebook, Social
    Networking


                               4
What needs to happen to
  make the EHR a killer app?
• Paradigm shift required in
  – Concept of EHR/EHRS
  – Recognition of all the stakeholders
  – Roles of stakeholders
  – Integration across all domains relating to
    health and healthcare
  – Creating common language
  – Relationship between venders and users

                                                 5
What needs to happen …
• Greater, quicker and appropriate use of
  available technology
• Adopting more quickly to change
• Faster creation and more effective use of
  required resources: applications,
  standards, workforce
• Sharing data, knowledge, and processes
  – Cooperative competition
• Stitch together current silos
                                              6
Technology Advances
• Mobile devices
    – iPad and similar devices
    – Personal health devices
•   Ubiquitous wireless
•   Voice recognition – still coming but useful
•   Virtual reality – IBM’s Watson
•   Cloud computing
•   RFID
                                                  7
From molecules to population
Molecular        Clinical         Patient           Public          Population
 Biology        Research           Care             Health            Health




                 Individual, Family, Community, Societies

             Site of Care: Intensive care, inpatient, ambulatory,
            emergency department, long term care, home care

                            Clinical Specialties

                                  Global



                                                                           8
Components of communication
• Data
  – Semantically interoperable, high quality, timely
• Knowledge
  – Appropriate, accessible, comprehensive
• Information
  – Actionable, focused, clear, reduces uncertainty
• Judgment
  – Human input based on experience and observation;
    an intangible component
• Wisdom
  – Individuals trained in how to use data, knowledge,
    and information

                                                         9
Application of HIT
                                            Understand                    Outcome
Understand the       Understand            measurements      Implement
problem to be      causes, factors,          and data         proposed
   solved.             issues               required to       solution.
                                           monitor & solve




                                                                          Evaluate
                                                                          outcome
                                      Feedback Loop


   Articulate health IT problems with the
   precision of a scientific hypothesis.

                                                                                     10
The Spectrum of Problem
            Solving
• Science base of biology and medicine
• Collection and interpretation of signals
• Multiple (re-use) of data
• Application of science and data in clinical
  care
• Extension of clinical care to populations


                                                11
Application Areas
• Genetics
   – Genomics, proteomics, metabolomics, biomarkers, biomedical
     modeling…
• Clinical Research
• Clinical systems (HIS, CPOE, ePrescribing, CDW, …)
   – Clinical domain systems (cardiology, oncology, ,,,)
   – Electronic Health Records
       • EHR, EMR, PHR, Regional, National, Population

• Public Health
• Telemedicine
   – Mobile and personal medical devices
• Educational Tools
                                                                  12
Genetics
• Gene mutation will identify many treatable genes
  such as Hirschsprung’s disease, muscular
  dystrophy, and cystic fibrosis
• Drug treatments are already influenced by
  genomic information
  – The anticoagulant drug warfarin has a narrow
    therapeutic window - too high a dose, patient can
    bleed to death; too low a dose, clots remain unclotted.
    Genetic information [certain versions of two genes
    CYP2C9 and VKORC1] are highly predictive of rate of
    metabolizing warfarin.

                                                         13
New Associations
• EHR must include genetic information
  – Biomarkers need to be included in EHR with
    meaning and actions included in an
    accompanying knowledge base
  – Gene mutations need to be included with links
    to meaning and actions including in an
    accompanying knowledge base
  – Phenotype sets need to be linked to a disease


                                                14
Resulting Behavior Changes
• Physicians need not become geneticists.
  Computers will use associated knowledge
  to suggest actions based on biomarkers,
  gene data, and phenotypes
• Physicians will become the “action arm”
  with computers being the “thinking arm”
• Physicians role is as a participating
  service

                                        15
Changing demands
• Aging population, world wide. In U.S., a
  citizen becomes 65 years old every 6
  seconds. Over the next 30 years, we will
  add 20 million persons to the over 65
  category.
• Current health care systems cannot
  handle this volume.
• The role of primary care giver role will be
  shared with less trained persons.
                                                16
Changing role of patients
• Increased participation and responsibility
  for one’s own health
• Requires new methods of education,
  monitoring, networking, data access
  – Personal Health Records and patient portals
• Addressing health disparities
• Treating social and environment and
  cultural issues

                                                  17
A killer app delivers …
• Patient safety
• Efficient and effective health care delivery
• Health surveillance, bio-defense and natural
  disaster health data management
• Real quality, reduced uncertainty, trust
• Cost containment in face of increasing costs of
  healthcare
• Accommodation of an aging and mobile
  population
• Effective management of chronic disease
• Higher quality of life as well as longevity
                                                    18
A killer app delivers …
• Equal access to care
• Consumer sophistication and knowledge in health;
  mobility
• Increasing continuous uses of data – translational
  medicine
• Changes in doctor’s information gathering skills
• Increase in options for testing and treatment
• Limited connectivity among providers with multiple
  providers involved in care
• The Healthcare Gamble – who calls the play?

                                                  19
A killer app delivers …
• Practice of medicine that is predictive, personalized,
  pre-emptive, and participatory [the 4Ps]
• Accommodating increasing limitations of resources:
   –   Decreasing number of providers
   –   Smaller hospitals disappearing
   –   Long waits for appointments
   –   Few walk-in appointments available
• Changing models for healthcare
   –   Consumer driven health care
   –   Health savings accounts
   –   Shopping mall clinics, Doc in Box clinics
   –   Wal-Mart, Google and Microsoft movement into healthcare

                                                           20
A killer app accommodates …
•   Volume of data about a patient has increased
    tremendously over the past decades
    –   Increasing number of diagnostic tests
    –   Increasing numbers and modality of images
    –   Genetic testing
    –   Access to data at place and time of decision making is
        critical
    –   Informed decision requires data
    –   Data must be used for multiple purposes
    –   From bytes to kilobytes to megabytes to gigabytes to
        terabytes to petabytes to exabytes to zettabytes to …
                                                             21
A killer app accommodates …
•   Sources and amount of knowledge have
    increased exponentially over the past decades
•   NLM indexes over 1 million documents each
    year
•   Undergraduate and graduate education is
    based on out-of-date concepts
•   Continuing medical education is inadequate
•   We can’t learn fast enough to be effective
•   New knowledge requires new skills and new
    understanding

                                                22
Killer app EHR provides …
• Data and data management
  – The right data and only the right data
  – Complete, aggregated, timely, trustworthy, unambiguous,
    reusable, logically accessible
  – Event driven displays, logically driven
• Knowledge and knowledge management
  – Evidence-based, up-to-date, appropriate, integrated into work
    flow, human and computer useable
• Processes and work flow
  – Effectively and efficiently combines data with knowledge to
    enable optimum human decision-making
  – Monitor decisions and outcomes and provide safety checks,
    feedback and recommendations
  – Integrate data collection, presentation and decision support
    transparently into care delivery process

                                                                    23
Requires paradigm shifts
• Technologists – more appropriate use of technology;
  understanding the problems that need to be solved; better
  coupling with the clinical community
• Clinical community – recognize what technology can do to
  significantly enhance health care; become the drivers for the
  use of eHealth; understand value of team approach that
  includes the patient
• Patient – Accept responsibility for one’s own health; become
  engaged in decision-making related to one’s own health;
  enhanced awareness of personal risk factors; practice
  prevention

                                                            24
EHR – The Centerpiece of HIT


       Data Creation
                                  EHR
      Data Collection                                    The Enablement
                                 Patient Care
     Data Interchange
     Data Aggregation         Personalized Care
                               Community Care
                                Public Health


                              Includes the service   Proactive interpretation
Real-time integration of                             of data to direct behavior
                              functions:
knowledge to direct and                              to enable quality care.
                              HIS, CPOE, CDS, e
control collection of data.
                              Prescribing, billing


                                                                           25
Enabling Better Health
 EHR systems must be adaptive. We need to be
  able to include any new data element (self-
  defined) without additional programming.
 Exchange of data should be driven by filters or a
  defined set of business rules based on data
  elements.
 Systems should use Enterprise Architecture
  (SOA) approach in order to accommodate new
  functionalities and new technologies.

                                                  26
Possible Scenario
                           Knowledge Database



           Institutional                 Clinical
    Data      Data                        Data           Data Mining
            Repository                  Warehouse


                                                       Push, pull or query based


               Service
                                             The
                               Filter
            Applications                                            National
           (CPOE, ePres                 Patient-centric
                                                                    Linkage
            cribing, etc.)              Essential EHR


                       Other             Contained
                       systems           in Regional
                                         HIE
                                                                          27
EHR
• Architecture of EHR must support at variety of
  uses.
   – Requires independence of data from data
     collection and application set
• Data must be interoperable; it must be
  automatically reusable, capable of continuous
  use
• It must be capable of integrating with new data
  to produce new value and understanding.
• Granularity of data must start at lowest levels to
  permit effective computer analyses and
  understanding
• Reevaluate patient care and treatment as new
                                                     28
  data enters incorporating old data
EHR Issues
• Usability is key – minimize keystrokes for input
  and query
• Every user, regardless of level, must understand
  the value of the data
• Think ahead of user – alert fatigue can be
  avoided by walking behind when appropriate
  and alert only what is important
• Capture data from least expensive source but
  maintain quality


                                                 29
EHR Issues
• Free text is necessary as modifiers but attached
  to structure
• Cognitive support provides intelligent interaction
  with content
• Is an active partner with human in awareness,
  evaluation and decision making
• Supports push, pull, interactive queries,
  packaged queries, event-based queries


                                                   30
Challenges
• Privacy issues; recognize that personal control of
  data may harm creation of new knowledge and
  seamlessly connecting the contributing domains for
  the most effective care
• Identification and implementation of standards for
  data and data exchange
• Controlled and purposeful exchange of data
• Quality of data is insured through process,
  algorithms, and certainty factor
• Addresses provenance


                                                  31
Match Computational Approach to
                    Complexity of Data
                                      Automation


                                              Evidence-
                                               based
                                 Work lists   advisors
                                                           Decision
     Connectivity                                          Support
                                                Disease
                                 Aggregate
Stead WW. Electronic Health                   management
                                   EHR
Records. In: Rouse
WB, Cortese DA, eds.
                                              dashboards
Engineering the system of
healthcare delivery.
Tennenbaum Institute Series
on Enterprise Systems, Vol. 3.
Amsterdam: IOS Press; 2009.

                                      Data Mining
U.S. Focus
• HIE and interoperability (probably the #1
  discussion issue in the town-hall session)
• Usability
• Vendor relations and vendor accountability
• Need for reimbursement reform before
  providers will benefit from HIT
• Data sharing, as well as privacy, consent,
  and cases of breach
                                           33
U.S. Focus
• Stories of successful overhead reduction
• Use of more “scientific methods” of
  research and testing to determine future
  mandates, such as Meaningful Use,
  Phase 3
• Patient buy-in and collaboration



                                             34
Informatics
• Within Informatics is the power to bridge
  existing silos and significantly advance
  health, longevity and quality of life for all
  citizens of the world.
• This achievement can only happen through
  the global community acting together, sharing
  costs and responsibility.
• The inequalities of the world, the globally
  growing aging population, and economics
  demand this action be taken.
                                              35
Conclusion / Summary
• The pace of technology has been paced
  by Moore’s law: roughly, computational
  power doubles approximately every two
  years
• Use of technology – informatics – has not
  kept pace. The future of health care
  depends on our getting ahead of the curve
• That step demands a step change –
  revolution, not evolution!
                                          36
The Final Word
• Informatics and HIT holds the promise for a
  better world.
• Limited resources requires working together and
  sharing everything.
• We must speak the same language with the
  same meaning.
• Connectivity and communication is essential.
• Leadership and commitment of governments are
  a necessity.
• Will the EHR become the killer app in our
  lifetime?                                      37

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EHR - The Killer App ?

  • 1. EHR – The Killer App? HINZ Bringing the Electronic Health Record to Life 21 June 2012 W. Ed Hammond. Ph.D., FACMI, FAIMBE, FIMIA, FHL7 Director, Duke Center for Health Informatics Director, Applied Informatics Research, DHTS Associate Director, Biomedical Informatics Core, DTMI Professor, Department of Community and Family Medicine Professor Emeritus, Department of Biomedical Engineering Adjunct Professor, Fuqua School of Business Duke University Chair Emeritus, HL7 2
  • 2. What is a killer app? An application that accelerates the adoption and ubiquitous use of the application. 3
  • 3. Killer apps • Personal computer • World-wide web • Wireless networks • Google, Facebook, Social Networking 4
  • 4. What needs to happen to make the EHR a killer app? • Paradigm shift required in – Concept of EHR/EHRS – Recognition of all the stakeholders – Roles of stakeholders – Integration across all domains relating to health and healthcare – Creating common language – Relationship between venders and users 5
  • 5. What needs to happen … • Greater, quicker and appropriate use of available technology • Adopting more quickly to change • Faster creation and more effective use of required resources: applications, standards, workforce • Sharing data, knowledge, and processes – Cooperative competition • Stitch together current silos 6
  • 6. Technology Advances • Mobile devices – iPad and similar devices – Personal health devices • Ubiquitous wireless • Voice recognition – still coming but useful • Virtual reality – IBM’s Watson • Cloud computing • RFID 7
  • 7. From molecules to population Molecular Clinical Patient Public Population Biology Research Care Health Health Individual, Family, Community, Societies Site of Care: Intensive care, inpatient, ambulatory, emergency department, long term care, home care Clinical Specialties Global 8
  • 8. Components of communication • Data – Semantically interoperable, high quality, timely • Knowledge – Appropriate, accessible, comprehensive • Information – Actionable, focused, clear, reduces uncertainty • Judgment – Human input based on experience and observation; an intangible component • Wisdom – Individuals trained in how to use data, knowledge, and information 9
  • 9. Application of HIT Understand Outcome Understand the Understand measurements Implement problem to be causes, factors, and data proposed solved. issues required to solution. monitor & solve Evaluate outcome Feedback Loop Articulate health IT problems with the precision of a scientific hypothesis. 10
  • 10. The Spectrum of Problem Solving • Science base of biology and medicine • Collection and interpretation of signals • Multiple (re-use) of data • Application of science and data in clinical care • Extension of clinical care to populations 11
  • 11. Application Areas • Genetics – Genomics, proteomics, metabolomics, biomarkers, biomedical modeling… • Clinical Research • Clinical systems (HIS, CPOE, ePrescribing, CDW, …) – Clinical domain systems (cardiology, oncology, ,,,) – Electronic Health Records • EHR, EMR, PHR, Regional, National, Population • Public Health • Telemedicine – Mobile and personal medical devices • Educational Tools 12
  • 12. Genetics • Gene mutation will identify many treatable genes such as Hirschsprung’s disease, muscular dystrophy, and cystic fibrosis • Drug treatments are already influenced by genomic information – The anticoagulant drug warfarin has a narrow therapeutic window - too high a dose, patient can bleed to death; too low a dose, clots remain unclotted. Genetic information [certain versions of two genes CYP2C9 and VKORC1] are highly predictive of rate of metabolizing warfarin. 13
  • 13. New Associations • EHR must include genetic information – Biomarkers need to be included in EHR with meaning and actions included in an accompanying knowledge base – Gene mutations need to be included with links to meaning and actions including in an accompanying knowledge base – Phenotype sets need to be linked to a disease 14
  • 14. Resulting Behavior Changes • Physicians need not become geneticists. Computers will use associated knowledge to suggest actions based on biomarkers, gene data, and phenotypes • Physicians will become the “action arm” with computers being the “thinking arm” • Physicians role is as a participating service 15
  • 15. Changing demands • Aging population, world wide. In U.S., a citizen becomes 65 years old every 6 seconds. Over the next 30 years, we will add 20 million persons to the over 65 category. • Current health care systems cannot handle this volume. • The role of primary care giver role will be shared with less trained persons. 16
  • 16. Changing role of patients • Increased participation and responsibility for one’s own health • Requires new methods of education, monitoring, networking, data access – Personal Health Records and patient portals • Addressing health disparities • Treating social and environment and cultural issues 17
  • 17. A killer app delivers … • Patient safety • Efficient and effective health care delivery • Health surveillance, bio-defense and natural disaster health data management • Real quality, reduced uncertainty, trust • Cost containment in face of increasing costs of healthcare • Accommodation of an aging and mobile population • Effective management of chronic disease • Higher quality of life as well as longevity 18
  • 18. A killer app delivers … • Equal access to care • Consumer sophistication and knowledge in health; mobility • Increasing continuous uses of data – translational medicine • Changes in doctor’s information gathering skills • Increase in options for testing and treatment • Limited connectivity among providers with multiple providers involved in care • The Healthcare Gamble – who calls the play? 19
  • 19. A killer app delivers … • Practice of medicine that is predictive, personalized, pre-emptive, and participatory [the 4Ps] • Accommodating increasing limitations of resources: – Decreasing number of providers – Smaller hospitals disappearing – Long waits for appointments – Few walk-in appointments available • Changing models for healthcare – Consumer driven health care – Health savings accounts – Shopping mall clinics, Doc in Box clinics – Wal-Mart, Google and Microsoft movement into healthcare 20
  • 20. A killer app accommodates … • Volume of data about a patient has increased tremendously over the past decades – Increasing number of diagnostic tests – Increasing numbers and modality of images – Genetic testing – Access to data at place and time of decision making is critical – Informed decision requires data – Data must be used for multiple purposes – From bytes to kilobytes to megabytes to gigabytes to terabytes to petabytes to exabytes to zettabytes to … 21
  • 21. A killer app accommodates … • Sources and amount of knowledge have increased exponentially over the past decades • NLM indexes over 1 million documents each year • Undergraduate and graduate education is based on out-of-date concepts • Continuing medical education is inadequate • We can’t learn fast enough to be effective • New knowledge requires new skills and new understanding 22
  • 22. Killer app EHR provides … • Data and data management – The right data and only the right data – Complete, aggregated, timely, trustworthy, unambiguous, reusable, logically accessible – Event driven displays, logically driven • Knowledge and knowledge management – Evidence-based, up-to-date, appropriate, integrated into work flow, human and computer useable • Processes and work flow – Effectively and efficiently combines data with knowledge to enable optimum human decision-making – Monitor decisions and outcomes and provide safety checks, feedback and recommendations – Integrate data collection, presentation and decision support transparently into care delivery process 23
  • 23. Requires paradigm shifts • Technologists – more appropriate use of technology; understanding the problems that need to be solved; better coupling with the clinical community • Clinical community – recognize what technology can do to significantly enhance health care; become the drivers for the use of eHealth; understand value of team approach that includes the patient • Patient – Accept responsibility for one’s own health; become engaged in decision-making related to one’s own health; enhanced awareness of personal risk factors; practice prevention 24
  • 24. EHR – The Centerpiece of HIT Data Creation EHR Data Collection The Enablement Patient Care Data Interchange Data Aggregation Personalized Care Community Care Public Health Includes the service Proactive interpretation Real-time integration of of data to direct behavior functions: knowledge to direct and to enable quality care. HIS, CPOE, CDS, e control collection of data. Prescribing, billing 25
  • 25. Enabling Better Health  EHR systems must be adaptive. We need to be able to include any new data element (self- defined) without additional programming.  Exchange of data should be driven by filters or a defined set of business rules based on data elements.  Systems should use Enterprise Architecture (SOA) approach in order to accommodate new functionalities and new technologies. 26
  • 26. Possible Scenario Knowledge Database Institutional Clinical Data Data Data Data Mining Repository Warehouse Push, pull or query based Service The Filter Applications National (CPOE, ePres Patient-centric Linkage cribing, etc.) Essential EHR Other Contained systems in Regional HIE 27
  • 27. EHR • Architecture of EHR must support at variety of uses. – Requires independence of data from data collection and application set • Data must be interoperable; it must be automatically reusable, capable of continuous use • It must be capable of integrating with new data to produce new value and understanding. • Granularity of data must start at lowest levels to permit effective computer analyses and understanding • Reevaluate patient care and treatment as new 28 data enters incorporating old data
  • 28. EHR Issues • Usability is key – minimize keystrokes for input and query • Every user, regardless of level, must understand the value of the data • Think ahead of user – alert fatigue can be avoided by walking behind when appropriate and alert only what is important • Capture data from least expensive source but maintain quality 29
  • 29. EHR Issues • Free text is necessary as modifiers but attached to structure • Cognitive support provides intelligent interaction with content • Is an active partner with human in awareness, evaluation and decision making • Supports push, pull, interactive queries, packaged queries, event-based queries 30
  • 30. Challenges • Privacy issues; recognize that personal control of data may harm creation of new knowledge and seamlessly connecting the contributing domains for the most effective care • Identification and implementation of standards for data and data exchange • Controlled and purposeful exchange of data • Quality of data is insured through process, algorithms, and certainty factor • Addresses provenance 31
  • 31. Match Computational Approach to Complexity of Data Automation Evidence- based Work lists advisors Decision Connectivity Support Disease Aggregate Stead WW. Electronic Health management EHR Records. In: Rouse WB, Cortese DA, eds. dashboards Engineering the system of healthcare delivery. Tennenbaum Institute Series on Enterprise Systems, Vol. 3. Amsterdam: IOS Press; 2009. Data Mining
  • 32. U.S. Focus • HIE and interoperability (probably the #1 discussion issue in the town-hall session) • Usability • Vendor relations and vendor accountability • Need for reimbursement reform before providers will benefit from HIT • Data sharing, as well as privacy, consent, and cases of breach 33
  • 33. U.S. Focus • Stories of successful overhead reduction • Use of more “scientific methods” of research and testing to determine future mandates, such as Meaningful Use, Phase 3 • Patient buy-in and collaboration 34
  • 34. Informatics • Within Informatics is the power to bridge existing silos and significantly advance health, longevity and quality of life for all citizens of the world. • This achievement can only happen through the global community acting together, sharing costs and responsibility. • The inequalities of the world, the globally growing aging population, and economics demand this action be taken. 35
  • 35. Conclusion / Summary • The pace of technology has been paced by Moore’s law: roughly, computational power doubles approximately every two years • Use of technology – informatics – has not kept pace. The future of health care depends on our getting ahead of the curve • That step demands a step change – revolution, not evolution! 36
  • 36. The Final Word • Informatics and HIT holds the promise for a better world. • Limited resources requires working together and sharing everything. • We must speak the same language with the same meaning. • Connectivity and communication is essential. • Leadership and commitment of governments are a necessity. • Will the EHR become the killer app in our lifetime? 37