Dystonia is a neurological movement disorder characterized by sustained muscle contractions causing abnormal twisting movements or postures. It has several subtypes classified by anatomical distribution, age of onset, or etiology. Primary dystonia is genetic while secondary dystonia can be caused by injury, drugs, infections, or other neurological conditions. Symptoms vary but commonly involve twisting motions and abnormal postures. Treatment involves oral medications, botulinum toxin injections, surgery such as deep brain stimulation, or other therapies depending on the severity and type of dystonia.
Not epileptic
•Wrong seizure type (semiology)
•Wrong epileptic syndrome
•Wrong interpretation of EEG and imaging
When to start a drug?
•Which drug and in what dose?
•When to change the drug?
•When (and how) to add a second drug (and which one)?
•When to stop the drug(s)?
•When to consider alternative therapies, including surgery?
Not epileptic
•Wrong seizure type (semiology)
•Wrong epileptic syndrome
•Wrong interpretation of EEG and imaging
When to start a drug?
•Which drug and in what dose?
•When to change the drug?
•When (and how) to add a second drug (and which one)?
•When to stop the drug(s)?
•When to consider alternative therapies, including surgery?
semiological classification of seizure, localisation and lateralisation Vinayak Rodge
Semiologial classification plays an important role in proper diagnosis and treatment of epilepsy .it also has localizing and lateralizing value which helps in epileptic surgical interventions .
semiological classification of seizure, localisation and lateralisation Vinayak Rodge
Semiologial classification plays an important role in proper diagnosis and treatment of epilepsy .it also has localizing and lateralizing value which helps in epileptic surgical interventions .
Antipsychotics, also known as neuroleptics, are a class of medications primarily used to manage symptoms of psychosis, a mental state characterized by impaired thinking, emotions, and behaviors, often seen in conditions like schizophrenia, schizoaffective disorder, and certain mood disorders. These medications work by modulating neurotransmitters in the brain, particularly dopamine, to alleviate or reduce the severity of symptoms associated with psychosis. this ppt contains information regarding antipsychotics
Approach to dystonia by dr srimant pattnaiksrimantp
This presentation focuses on clinical approach to dystonia , based on latest recommendation by MDS and other articles . Comments and criticism are highly welcome .
Effective treatment for epilepsy in Mindheal Homeopathy clinic ,Chembur, Mumb...Shewta shetty
"epilepsy-it is a brain disorder in which the person has repeated convulsions over a period of time. Epilepsy occurs when permanent changes in the brain tissue cause it to be excitable or jumpy. The brain sends out abnormal signals. Mindheal homeopathy is more effective in the treatment of epilepsy then conventional medicine."/>
Effective treatment for epilepsy in Mindheal Homeopathy clinic ,Chembur, Mumb...Shewta shetty
"epilepsy-it is a brain disorder in which the person has repeated convulsions over a period of time. Epilepsy occurs when permanent changes in the brain tissue cause it to be excitable or jumpy. The brain sends out abnormal signals. Mindheal homeopathy is more effective in the treatment of epilepsy then conventional medicine."/>
Central Nervous System, Epilepsy, Parkinson, Alzheimer, Stroke and Migraine.Dr. Kiran Dhamak
Central Nervous System is one of the unit in Pharmacotherapeutics Subject which is for Second Year Diploma in Pharmacy. The unit covers diseases like Epilepsy, Parkinson, Alzheimer, Stroke and Migraine. The presentation includes the point as per diploma in pharmacy students may understand very easily. The syllabus is framed by Pharmacy Council of India which is implemented by MSBTE ER 2020-2021
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...The Lifesciences Magazine
Deep Leg Vein Thrombosis occurs when a blood clot forms in one or more of the deep veins in the legs. These clots can impede blood flow, leading to severe complications.
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Health Education on prevention of hypertensionRadhika kulvi
Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The
The Importance of Community Nursing Care.pdfAD Healthcare
NDIS and Community 24/7 Nursing Care is a specific type of support that may be provided under the NDIS for individuals with complex medical needs who require ongoing nursing care in a community setting, such as their home or a supported accommodation facility.
2. What is Dystonia?
• Dystonia is a neurologic movement disorder
characterized by sustained muscle
contractions, usually producing twisting and
repetitive movements or abnormal postures
or positions.
3. Dystonia Chorea Myoclonus Tics
Sustained muscle
contraction
Sudden Sudden Sudden
Repetitive and
patterned
Irregular and
purposeless
Brief and jerky Brief and jerky but
patterened
Abnormal posture
or position
Distal
predominance
Not patterened Can be suppressed
temporarily and
may persist during
sleep
4. Phenomenology of Dystonia
Clinically unifying and consistent features are:
• 1. Relatively longer duration contraction
• 2. Simultaneous contraction of agonist and
antagonist
• 3. Twisting of the affected body part
• 4. Continual contraction of same group of
muscles
5. Cont
• Painful /painless:- most dystonia are painless
except cervical dystonia(75%)
• Diurnal variation:- only present in DRD
• Aggravating factors:-fatigue, stress, emotions,
pregnancy
• Relieving factors:- relaxation ,hypnosis, sleep
• Associated features:-
– Other abnormal movements :- tremor, myoclonus
– Other neurological deficit:- weakness, spasticity, reflex
change, dementia, seizures, abnormal eye movements
6. Classification of dystonia
• Anatomical classification
• On the basis of etiology
• on the basis of onset of symptoms
8. Classification on the basis of age of
onset
• Childhood onset---- 0 to 12 years.
• Adolescent onset---- 13 to 20 years.
• Adult onset---- older than 20 years.
• In broader terms:
– Early onset---- before 20 years
– Late onset---- later than 20 years or in late
twenties.
9. On the basis of etiology
• Primary dystonia.
• Secondary dystonia
• Metabolic disorders Heredodegenerative
dystonia
• Drugs
10. Inherited Primary Dystonia
• Group of Genetic disorders usually onset in
childhood.
– Primary torsion dystonia intermittent unilateral
posturing of lower extremities progresses to all 4
limbs and axial musculature.
– Dopa - responsive dystonia aka Sagawa Syndrome
hallmark is diurnal variation
» All children with progressive dystonia should receive a
trial of L-dopa therapy to screen for dopa -responsive
dystonia
11. cont
– Myoclonus dystonia characterized by dystonia
involving the upper limb, head and/or neck as well
as myoclonic movements of these region. May
take on tremor like appearance termed dystonic
tremors.
• In primary dystonias although the main
clinical features are motor there may be
increased risk of depression, anxiety, OCD and
screening of psychologicaal comorbidities
shouldnot be overlooked.
12. Secondary dystonia
• Perinatal cerebral injury
• Infectious and post infectious
• Head trauma
• Stroke
• AV malformation
• Multiple sclerosis
• brain tumor
• Hypoparathyroidism,hypoxia
• Peripheral injury
13. Signs Potentially Suggestive of
Secondary Dystonia
• Patient history of a possible causative factor.
• Associated neurologic signs.
• Dystonia that occurs during periods of rest.
• Initial leg involvement during adulthood.
• Hemidystonia.
• Early onset of speech disturbance.
• Abnormal laboratory test results .
• Abnormal neuroimaging results.
• Signs suggestive of psychogenic causes.
14. • Cerebral palsy is a group of permanent disorder
of movement and posture that are attributed to
non progressive disturbances in developing fetal
or infant brain
– Spastic diplegia (35%)
– Spastic quadriplegia (20%)
– Hemilpegia (25%)
– Extrapyramidal ;athetoid dyskinetic (15%)
• Static encephalopathy, but features such as
movement disorder and orthopedic complication
can change or progress over time.
18. Spectrum of Drug Induced Dystonia
• Acute Dystonic Reaction
– Occurs in 1st few days of exposure, typically
involves torticollis, retrocollis, oculogyric crisis and
tongue protrusion or laryngospasm.
– IV diphenhydramine 1-2mg/kg/dose
• Neuroleptic Malignent Syndrome
– Occurs within a month of initiation or dose
increase or withdrawel of dopamine agent
– Severe rigidity, high fever, delirium, dystonia
19. CONT
• Tardive dyskinesias
– Develop after more than 3 months of use.
– Involvement of the face particularly mouth, lips
and/or jaw with chewing jaw thrusting is
characteristic
– Removal of offending agent may not result in
clinical improvement
– Use of doapmine depleters such as reserpine is
helpful.
23. Pilot dose of combination of levodopa and carbidopa
Not effective
Generalized or
segmental
Trihexyphenidyl
Gabapentin
Clonidine, tetra
benazine,beclofen,
benzodiazepine
Severely impaired function
consider pallidal stimulation
and intrathecal baclofen
Focal
Botulinum toxin
Effective
DRD. Continue
therapy
24. Chemodenervation
• BOTULISM TOXIN A
• BOTULISM TOXIN B
– are commonly used for direct injection into the
affected muscles.
– MODE OF ACTION Blocks the release of
acetylcholine,thus relaxes the muscle