2. Proliferative Fibroplasia of Subcutaneous palmar tissue
Occurring in the form of Nodules and cords
Resulting in Secondary progressive & irreversible finger joint flexion contracture
4. DUPUYTREN DIATHESIS
• Prone for progressive & recurrent disease
• ECTOPIC DEPOSITS OF DUPUYTREN DISEASE
- Ledderhose disease- 5% of patients with dupuytren disease have
similar lesion in medial plantar fascia of one or both feet.
- Peyronie disease – 3% patients have plastic penile induration
- Garrod nodules/ Knuckle pads – dorsum of PIP joints
5. • Age - 40- 60 years
• Male – 10 times common than female
• According to Mc Farlane, the disease occurs significantly earlier in
men than women
• Common in individuals of Scandinavian & Celtic origin
• Associated with diabetes, epilepsy, alcoholism, smoking
• 45% bilateral
• Rarely symmetrical
6. • Exact cause – unknown
• Contributing factors –
Hand trauma
Autosomal dominant inheritance
Vascular insufficiency
Smoking
10. Clinical features
• Lesion begins usually on ulnar side of hand at distal palmar crease
which progress to involve ring finger > little finger > than other digits
combined
• MCP & PIP joint contracture
• Itching or occasional pain early in development of nodules