This document provides an overview of confined space safety regulations and procedures. It defines a permit-required confined space as one that has atmospheric, engulfment, or other serious hazards. Employers must implement a confined space program including posting signs, issuing entry permits, and designating attendant and entry supervisor roles. An incident at a Valero refinery is presented as a case study where two contract workers were fatally injured by nitrogen inhalation while performing maintenance in a reactor.