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DNA/Mutation Review
• What is the subunit/monomer of DNA called?
• Name 3 ways DNA is different from RNA?
• Name the two bases that are examples of
Purines
Pictionary Question
• Guess the word!
• Name the four bases of RNA
• What type(s) of RNA are involved in
translation?
• Ribosomes are made of which type of RNA?
• Region of DNA that RNA polymerase first
binds to during transcription
Music Trivia
Name the artist!
• 3 base combinations that codes for an amino
acid are called __________ and are located on
___RNA.
• What are the subunits/monomers of proteins?
• A mutation that could cause a protein to be
too long would most likely take place in the
_____ codon.
• A substitution mutation causes the SAME
amino acid to be coded for – this is an
example of a _______ mutation.
Sports Trivia
• Who was the MVP of Super Bowl 48?
Mutations
• Identify one thing that could cause mutations
in your DNA?
• Anti-codons are located on the ___RNA.
Is this pedigree tracking a
dominant or recessive trait?
• Name of the enzyme involved in transcription.
Sports Trivia
• What team did Pete Carroll coach before the
Seahawks?
Fill in the blank
• The sugar-phosphate backbone in DNA is
connected by strong ________ bonds and the
bases are connected by weaker ________
bonds.
• ___________ & ____________ mutations
cause frameshifts in the sequence after the
mutation occurs.
Music Trivia
• Identify the Artist!
• What is the central dogma of biology?
Transcription
• Transcribe the following DNA template
sequence:
TTCCGCGCATA
• The start codon on mRNA is complementary
to this DNA sequence __ __ __.
WHS Trivia
• Which Administrator, Mr. Criscione, Mr. Stutz,
or Ms. Hiatt, does NOT have children?
Sickle Cell
• What type of mutation in DNA causes Sickle
Cell?
• A DNA molecule was examined and around
20% of it was made of nucleotides with
Thymine bases. Around what % of the
molecule would consist of Guanine?
• Name the 3 bases that are examples of
pyrimidines.
• Mutations are more severe when they are in
DNA or RNA?
• Explain.
• Give me the anticodon sequence for the
template DNA sequence:
TACGATTTC
Punnett Square Practice
• Being able to roll your tongue is a recessive
trait. Mom cannot roll her tongue (she is a
carrier though) and dad can. What are the
chances their kid will be able to roll his/her
tongue?
Bonus Question!
• Choose two players! Bring something to write
with.
DNA:

GTACCGTTTTATCG

DNA after mutation: G T A C C G T T T T A T T C G
1. Identify the mutation that occurred in DNA.
2. Transcribe and Translate both sequences.
3. Explain the impact it had on the final protein.

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Dna mutation review (1)

Editor's Notes

  1. nucleotide
  2. DNA hasT’s (not U’s)Double stranded (vs single stranded)DNA has deoxyribose sugar (not ribose sugar)DNA stays in the nucleus
  3. Adenine and guanine
  4. Deoxyribose
  5. Adenine, uracil, guanine, cytosine
  6. mRNA,tRNA, rRNA
  7. rRNA!
  8. promoter
  9. Codons, mRNA
  10. Amino acids
  11. stop
  12. neutral
  13. Malcom Smith
  14. Random errors in DNA replication, radiation, UV rays, harsh chemicals…etc.
  15. tRNA
  16. Recessive. If a child has a dominant disease, at least one of the parents would also have to have the disease. Individual 17’s parents both do not have it.
  17. RNA Polymerase
  18. USC Trojans
  19. Covalent, hydrogen
  20. Insertions and deletions
  21. DNA  RNA  Protein
  22. AAGGCGCGUAU
  23. TAC
  24. Mr.Criscione
  25. substitution
  26. 30% (Because if it’s around 20% Thymine, it must be about 20% Adenine. This leaves 60% which means Guanine and Cytosine are probably each around 30% of the molecule.)
  27. Cytosine, thymine, uracil
  28. U A C G A U U U G
  29. Rr x rr = 50% tongue rolling (rr), 50% non-tongue rolling (Rr)
  30. Inserted a T in the stop but stop codon was still ok (uag uaa)MET ALA LYS (STOP)This is an example of an insertion mutation that ended up being neutral for this gene.