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Diabetic Ketoacidosis
Walesa Ikowa
DIABETIC KETOACIDOSIS (DKA)
• Diabetic ketoacidosis (DKA) is the state of
uncontrolled catabolism associated with
insulin deficiency, resulting in hyperglycaemia
(RBS >11mmol/L), osmotic diuresis, and
dehydration and ketonaemia (>3mmol/L)
Acidaemia (blood pH <7.3), significant
ketonuria (2+or more or standard urinalysis).
• It is the commonest endocrine emergency
usually encountered in previously diagnosed
diabetics.
Investigations
• Random glucose
• U/E, Creatinine
• LFTs
• FBC
• Malaria parasite
• Urinalysis
• Urine m/c/s
• Arterial blood gases
Treatment
• General resuscitation: A, B, C.
• Airway: Ensure that airway is patent.
• If comatose, insert an airway.
• If comatose and has recently vomited, insert a
NGT, aspirate and leave on open drainage.
• Breathing: Give 100% oxygen where indicated.
Bag and mask ventilation if apnoeic.
Treatment
• Circulation: Insert two large bore IV cannulae
and take blood samples.
• If shocked (Tachycardia with poor capillary
refill time or hypotension) give 20 ml/kg 0.9
saline as quickly as possible, and repeat if
necessary up to a max of 60mls/kg.
Thank you

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DKA(1).pptx

  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. DIABETIC KETOACIDOSIS (DKA) • Diabetic ketoacidosis (DKA) is the state of uncontrolled catabolism associated with insulin deficiency, resulting in hyperglycaemia (RBS >11mmol/L), osmotic diuresis, and dehydration and ketonaemia (>3mmol/L) Acidaemia (blood pH <7.3), significant ketonuria (2+or more or standard urinalysis). • It is the commonest endocrine emergency usually encountered in previously diagnosed diabetics.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20. Investigations • Random glucose • U/E, Creatinine • LFTs • FBC • Malaria parasite • Urinalysis • Urine m/c/s • Arterial blood gases
  • 21.
  • 22.
  • 23. Treatment • General resuscitation: A, B, C. • Airway: Ensure that airway is patent. • If comatose, insert an airway. • If comatose and has recently vomited, insert a NGT, aspirate and leave on open drainage. • Breathing: Give 100% oxygen where indicated. Bag and mask ventilation if apnoeic.
  • 24. Treatment • Circulation: Insert two large bore IV cannulae and take blood samples. • If shocked (Tachycardia with poor capillary refill time or hypotension) give 20 ml/kg 0.9 saline as quickly as possible, and repeat if necessary up to a max of 60mls/kg.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.