Discussion 2: Arthritis While arthritis impacts nearly 50 million adults in the United States, it is not a disease that is limited to adulthood. Consider the case of Ashley Russell. At the age of 14 months, Ashley was diagnosed with juvenile rheumatoid arthritis. As a baby, her parents noticed that her knee was always swollen and that she often wanted to be carried instead of walking on her own (Cyr, 2012). After seeking medical care, Ashley’s underlying disorder was discovered. Arthritis in children is not uncommon. According to the CDC (2011), an estimated 294,000 children under age 18 have some form of arthritis or rheumatic condition. Due to the prevalence of the disorder in both children and adults, you must understand the pathophysiology and symptoms of arthritis in order to properly diagnose and prescribe treatment. To prepare: · Review Chapter 37 in the Huether and McCance text and Chapter 24 in the McPhee and Hammer text. Identify the pathophysiology of osteoarthritis and rheumatoid arthritis. Consider the similarities and differences of the disorders. · Select two of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how the factors you selected might impact the pathophysiology of the disorders, as well as the diagnosis of and treatment for the disorders. Post A 1 page APA format 1. description of the pathophysiology of osteoarthritis and rheumatoid arthritis, including the similarities and differences between the disorders. 2. Then explain how the ( gender and ethnicity ) factors you selected might impact the pathophysiology of the disorders, as well as the diagnosis of treatment for the disorders. Course Readings · Huether, S. E., & McCance, K. L. (2012). Understanding pathophysiology (Laureate custom ed.). St. Louis, MO: Mosby. o Chapter 5, “Innate Immunity: Inflammation and Wound Healing” This chapter examines how the body responds to injury and infection by exploring the first, second, and third lines of defense. It also covers wound healing and alterations of the wound healing process. o Chapter 6, “Adaptive Immunity” This chapter examines the third line of defense, adaptive immunity. It also covers the roles of antigens and immunogens, the humoral immune response, cell-mediated immunity, and the production of B and T lymphocytes in the immune response. o Chapter 7, “Infection and Defects in Mechanism of Defense” This chapter covers the epidemiology, clinical presentation, and treatment of disorders resulting from infection, deficiencies in immunity, and hypersensitivity. It also examines the pathophysiology of an important immune disorder—HIV/AIDS. o Chapter 8, “Stress and Disease” This chapter evaluates the impact of stress on various body systems and the immune system. It also examines coping mechanisms and disorders related to stress. o Chapter 9, “Biology, Clinical Manifestations, and Treatment of Cancer” This chapter explores the developmental process of can.