anatomy of median nerve,course in arm and struthers ligament, branches in the forearm, carpal tunnel and course in hand, high and low median nerve injuries, principles of surgical management, pronator teres syndrome, anterior interosseous nerve syndrome, open and endoscopic carpal tunnel release
1.Anatomy
a.Course
b.Motor distribution
c.Sensory distribution
2.Common sites affected
3.Level of median nerve injury
4.Clinical feature with various test performed
5.Various syndromes related to median nerve
6.Treatment
7.Summary
Peripheral nerve damage affecting the upper extremities can vary widely in cause and extent.
Many disorders, ranging from mild carpal tunnel syndrome to severe brachial plexopathy, need to be considered in a patient presenting with pain, sensory loss, or weakness involving the shoulder, arm, or hand.
Injuries to the nerves of the upper limb can result from trauma, compression, lacerations, or certain medical conditions. Nerve injuries may lead to various symptoms, including pain, weakness, numbness, or loss of function in specific areas of the upper limb. Nerve injuries may range from mild to severe, and appropriate medical evaluation and treatment are essential. Physical therapy, splinting, medications, or in some cases, surgical intervention may be recommended based on the type and severity of the nerve injury. Early intervention is crucial for optimal recovery.
anatomy of median nerve,course in arm and struthers ligament, branches in the forearm, carpal tunnel and course in hand, high and low median nerve injuries, principles of surgical management, pronator teres syndrome, anterior interosseous nerve syndrome, open and endoscopic carpal tunnel release
1.Anatomy
a.Course
b.Motor distribution
c.Sensory distribution
2.Common sites affected
3.Level of median nerve injury
4.Clinical feature with various test performed
5.Various syndromes related to median nerve
6.Treatment
7.Summary
Peripheral nerve damage affecting the upper extremities can vary widely in cause and extent.
Many disorders, ranging from mild carpal tunnel syndrome to severe brachial plexopathy, need to be considered in a patient presenting with pain, sensory loss, or weakness involving the shoulder, arm, or hand.
Injuries to the nerves of the upper limb can result from trauma, compression, lacerations, or certain medical conditions. Nerve injuries may lead to various symptoms, including pain, weakness, numbness, or loss of function in specific areas of the upper limb. Nerve injuries may range from mild to severe, and appropriate medical evaluation and treatment are essential. Physical therapy, splinting, medications, or in some cases, surgical intervention may be recommended based on the type and severity of the nerve injury. Early intervention is crucial for optimal recovery.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
6. Type of lesion Cause Manifestations
Very high Saturday night palsy
Crutch palsy
Surgical procedures or trauma
around shoulders
Loss of function of triceps,
wrist drop, thumb drop, finger
drop
High Fracture of shaft of humerus Triceps spared, wrist drop,
thumb drop, finger drop
Low Injury at around lateral condyle
of humerus.
Wrist extensors spared
Thumb drop, finger drop
9. Median Nerve
• Aka laborer’s nerve
• Supplies all anterior compartment muscles of forearm except FCU and
medial half of FDF.
• In hand all thenar muscles except adductor pollicis.
• Anterior interosseous nerve: supplies FPL and lateral half of FDF
11. High median nerve injury low median nerve injury
Injury at and proximal to elbow Injury in distal third of forearm
Paralysis of all the muscles supplied by
median nerve in forearm and hand
Sparing of forearm muscles but muscles
of hand will be paralyzed.
In addition to the lower nerve lesion, the
long flexors of thumb, index and middle
finger, radial wrist flexors and the
forearm pronators are paralyzed
Patient unable to abduct the thumb and
sensation is lost over the radial three and
half digits
16. Ulnar nerve
• Aka Musician’s nerve
• Supply FCU and medial half of FDP in forearm
• All hypothenar muscles and adductor pollicis, lumbricles 3,4 and
palmar and dorsal interossei.
18. High ulnar nerve palsy Low ulnar nerve palsy
Injury proximal to the elbow Injury in distal third of forearm
Muscles of forearm involved Muscles of forearm spared
Sensory loss over palmar and dorsal
aspect of medial third of hand.
Sensory loss over palmar and dorsal
aspect of whole of little finger and ulnar
half of ring finger.
No sensory loss over proximal and middle
phalanx of little finger due to sapring of
dorsal cutaneous branch.
22. Egawa test
• With palm flat on the table, the patient is asked to move the middle
finger sideways.
23. Sciatic nerve
• Composed of fibers from L4, L5, S1, S2 and S3.
• Peripheral component is common peroneal nerve and deep
component is tibial nerve.
• Injury to sciatic nerve usually affects the superficial part of the nerve.
Hence the symptoms of common peroneal nerve palsy predominates.
24. Effects of sciatic nerve injury:
• Motor effects:
• Marked wasting of muscles below the
knee
• Weak flexon of knee
• Weak extension of hip.
• All the muscles below the knee are
paralyzed and the weight of the foot
causes it to assume the plantar flexed
position, or foot drop.
25. Effects of sciatic nerve injury:
• Sensory effect:
• Sensation is lost below the
knee, except for a narrow
area down the medial side
of the lower part of leg
(blue) and along the medial
border of the big toe ,
which is supplied by the
saphenous nerve.
27. Electromyography
• Involves recording of electric potentials
from needle electrode in muscle both
at rest and during voluntary
contraction
• Resulting electromyographic patterns
displayed on an oscilloscope
• Most useful for distinguishing between
and among myopathic and
neuropathic disorders.
28. Nerve Conduction Velocity
• Stimulation – stimulated electrically by an electrode placed on the
skin overlying the nerve-evokes a response from the muscle
innervated, AP propagates to innervate the muscle.
• Response – be seen, measured and palpated.
• Nerve - stimulated proximal to, distal to, and across the level of injury.
• Latency, amplitude of CMAP, NCV can be calculated
30. General considerations:
• In clean cut wounds, nerve repair done till 7 days
• In contaminated wounds , do loose end to end apposition or
suture to soft tissues
• Early active motion of all joints of involved extremity should be
started
• Gentle passive exercises
• Joints should be kept supple and soft tissue contractures
prevented
• Dynamic and static splinting
31. Surgical considerations:
Nerve Exploration
• Indications :
• Sharp injury has obviously divided a nerve
• Abrading, avulsing or blasting wounds
• Nerve deficit follows blunt or closed trauma with no clinical
or electrical evidence of regeneration
• Nerve deficit follows a penetrating injury with no evidence of
regeneration
• Timing :
• Primary repair done in 1st 6-8 hrs
• Delayed primary repair in first 7 -18 days in sharp cut wounds
32. Primary vs Delayed repair
Primary Repair Delayed repair
Indications Injury caused by sharp object, clean
wound, no major complicating injuries
Missed diagnosis, closed injury left
expectantly without signs of recovery, failed
primary repair
Advantages Nerve ends not retracted much,
rotational alignment relatively
undisturbed, no fibrosis
Infection is less, nerve graft or transfer or
tendon transfer can be planned
33. Types of nerve repair:
• Neurolysis
• Neurorrhaphy
• Nerve grafting
• Nerve Transfer
• Tedon grafting
34. Critical limit of delay
Nerve Critical limit of delay
Radial 15 months
PIN 9 months
Ulnar 9 mo ( high lesion), 15 months ( low lesion)
Median 9 mo ( high lesion), 12 mo ( low lesion)
Sciatic 12-15 months
CPN 12 months
35. Factors affecting outcome after repair:
• Age of patient
• Time between injury and repair
• Nature of nerve injury:Clean cut> Crush> Traction
• Level of injury: The higher the lesion,the worse the prognosis
• Associated vascular injury
• Length of injured segment: graft of >10 cm is unlikely to work
• Tpye of nerve
• Surgical skills