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The diaphragm is a dome-shaped musculotendinous structure that separates the thoracic and abdominal cavities. It is the primary muscle of respiration and has openings that allow structures to pass between the chest and abdomen. The diaphragm develops from septum transversum, dorsal mesentery of the esophagus, lateral body wall mesoderm, and pleuroperitoneal membranes. It forms during embryonic folding and development of the pleural cavities. Clinically, abnormalities can include congenital diaphragmatic hernia, accessory diaphragms, or eventration of the diaphragm.












