The document provides information on signs and symptoms of deteriorating patients. It discusses key terminology like signs and symptoms. It then outlines an approach to assessment using C-A-B-C-D-E mnemonic. Common presentations of deterioration like tachypnea, hypoxemia, tachycardia, hypotension, hypertension, decreased conscious level, and decreased urine output are described. Management focuses on identifying and treating the underlying cause while supporting organ functions.
Atrophic vaginitis, or vaginal dryness, is a condition caused by thinning tissue, decreased lubrication, and low estrogen levels.
Vaginal dryness is typical during and after menopause, due to the normal drop of estrogen levels in the body.
Genital prolapse, also known as pelvic organ prolapse (POP), occurs when the muscles and tissues that support the pelvic organs (such as the uterus, bladder, and rectum) weaken or stretch, leading to the descent of these organs into the vaginal canal. This condition is more common in women, especially those who have experienced childbirth, hormonal changes during menopause, or other factors that contribute to weakening pelvic floor muscles.
Atrophic vaginitis, or vaginal dryness, is a condition caused by thinning tissue, decreased lubrication, and low estrogen levels.
Vaginal dryness is typical during and after menopause, due to the normal drop of estrogen levels in the body.
Genital prolapse, also known as pelvic organ prolapse (POP), occurs when the muscles and tissues that support the pelvic organs (such as the uterus, bladder, and rectum) weaken or stretch, leading to the descent of these organs into the vaginal canal. This condition is more common in women, especially those who have experienced childbirth, hormonal changes during menopause, or other factors that contribute to weakening pelvic floor muscles.
under and post graduate best presentation ever about the assisted vaginal delivery,operative vaginal delivery, or instrumental vaginal delivery.
done by waill salan al.timeemi/stager 2014-2015/ Iraq-al.qadisiyyah college of medicine.
under and post graduate best presentation ever about the assisted vaginal delivery,operative vaginal delivery, or instrumental vaginal delivery.
done by waill salan al.timeemi/stager 2014-2015/ Iraq-al.qadisiyyah college of medicine.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
4. TERMINOLOGY
SIGN: A medical sign is a physical response linked medical fact or
characteristic that is detected by a physician, nurse, or medical device during
the examination of a patient.
1. Prognostic signs: These are signs that point to the future.
2. Anamnestic signs: These signs point to parts of a person’s medical history.
3. Diagnostic signs: These signs help the doctor recognize and identify a
current health problem.
4. Pathognomonic signs: This means that a doctor can link a sign to a condition
with full certainty.
5. SYMPTOMS: A symptom is the subjective experience of a potential health
issue, which cannot be observed by a doctor.
1. Remitting symptoms: When symptoms improve or resolve completely, they
are known as remitting symptoms.
2. Chronic symptoms: These are long-lasting or recurrent symptoms. Chronic
symptoms are often seen in ongoing conditions, such as diabetes, asthma,
and cancer.
3. Relapsing symptoms: These are symptoms that have occurred in the past,
resolved, and then returned.
7. IMMEDIATE ASSESMENT
Immediate assessment done by using the mnemonic C-A-B-C-D-E
1. Control of obvious problem
2. Airway
3. Breathing
4. Circulation
5. Disability
6. Exposure
8. CONTROL OF OBVIOUS PROBLEM
If the patient has any ongoing problem going on then focus on treating the
cause.
For example, if the patient has ventricular tachycardia on the monitor or
significant blood loss is apparent, immediate action is required.
9. AIRWAY AND BREATHING
If the patient is talking in full sentences, then the airway is clear and breathing
is adequate. A rapid history should be obtained while the initial assessment is
undertaken.
Breathing should be assessed with a focused respiratory examination.
Oxygen saturations and ABGs should be checked early.
11. CIRCULATION
A focused cardiovascular examination should include heart rate and rhythm,
jugular venous pressure, evidence of bleeding, signs of shock and abnormal
heart sounds.
The carotid pulse should be palpated in the collapsed or unconscious patient,
but peripheral pulses also should be checked in conscious patients.
The radial, brachial, foot and femoral pulses may disappear as shock
progresses, and this indicates the severity of circulatory compromise.
12. DISABILITY
Conscious level should
be assessed using the
GCS. A brief
neurological examination
looking for focal signs
should be performed.
Capillary blood glucose
should always be
measured to exclude
hypoglycemia or severe
hyperglycemia.
13. EXPOSURE AND EVIDENCE
‘Exposure’ indicates the need for targeted clinical examination of the
remaining body systems, particularly the abdomen and lower limbs.
‘Evidence’ may be gathered via a collateral history from other health-care
professionals or family members, recent investigations, prescriptions or
monitoring charts.
14. NEWS SCORE
(NATIONAL
EARLY WARNING
SCORE)
NEWS score is a tool
developed by the Royal
College of Physicians which
improves the detection and
response to clinical
deterioration in adult
patients and is a key element
of patient safety and
improving patient outcomes.
15. NEWS SCORE FREQUENCY OF OBSERVATIONS CLINICAL RESPONSE
TOTAL ZERO MINIMUM 12 HOURLY / 4
HOURLY IN ADMISSION AREA
Continue routine NEWS monitoring with
every set of observations.
TOTAL 1-4 MINIMUM 4 HOURLY Inform registered nurse or the medical team
if problem escalated.
TOTAL 5-6 OR 3 IN
ONE PARAMETER
MINIMUM ONE HOURLY Inform registered nurse or the medical team.
Consult with senior trainee for urgent
assessment.
TOTAL 7 OR MORE CONTINOUS MONITORING OF
ALL VITALS
Inform registered nurse, senior trainee, on-
call consultant and inform the critical care
unit.
16. COMMON PRESENTATIONS OF DETERIORATION
As patients become critically unwell, they usually manifest physiological
derangement. The principle underpinning critical care is the simultaneous
assessment of illness severity and the stabilization of life-threatening
physiological abnormalities.
The goal is to prevent deterioration and effect improvements, as the diagnosis
is established and treatment of the underlying disease process is initiated.
It can be useful to consider the physiological changes as a starting point to
help delineate urgent investigations and supportive treatment, which should
proceed alongside the search for a definitive diagnosis.
17. TACHYPNEA
A raised respiratory rate (tachypnea) is the earliest and most sensitive sign of
clinical deterioration. Tachypnea may be primary (i.e. a problem within the
respiratory system) or secondary to pathology elsewhere in the body.
Attention should be paid to the adequacy of chest expansion, air entry and
the presence of added sounds such as wheeze.
18. Analysis of an arterial blood sample is especially helpful in narrowing the
differential diagnosis and confirming clinical suspicion of severity. The ‘base
excess’ provides rapid quantification of the component of disease that is
metabolic in origin. A base excess lower than −2 mEq/L is likely to represent a
metabolic acidosis. A simple rule of thumb is that a lactate of more than 4
mmol/L or a base deficit of more than 10 mEq/L should cause concern and
trigger escalation to a higher level of care.
In addition to clinical examination, chest radiography and bedside ultrasound
can help to distinguish the cause of poor air entry; consolidation and effusion
can be readily identified and a significant pneumothorax can be excluded.
19. HYPOXEMIA
Low arterial partial pressure of oxygen (PaO2) is termed hypoxemia. It is a
common presenting feature of deterioration. Hypoxia is defined as an
inadequate amount of oxygen in tissues (or the inability of cells to use the
available oxygen for cellular respiration).
Hypoxia may be due to hypoxemia, or may be secondary to impaired cardiac
output, the presence of inadequate or dysfunctional haemoglobin, or
intracellular dysfunction.
20. Over 97% of oxygen carried in the blood is bound to haemoglobin. The
haemoglobin–oxygen dissociation curve delineates the relationship between
the percentage saturation of haemoglobin with oxygen (SO2) and the partial
pressure (PO2) of oxygen in the blood. Shifts of the oxy-haemoglobin
dissociation curve can have significant implications in certain disease
processes.
When attempting to determine the cause of hypoxemia, it is useful to
consider whether the primary physiological mechanism is a type of shunt, or
one of the many causes of ventilation–perfusion mismatch, such as alveolar or
central hypoventilation.
Oxygen therapy is given as management but it should be titrated to avoid
hyperoxia.
23. TACHYCARDIA
It is defined as heart rate over 100 beats per minute.
Intrinsic cardiac causes (atrial fibrillation (AF), atrial flutter, supraventricular
tachycardia and ventricular dysrhythmias) are less common in the general
inpatient population than secondary causes of tachycardia.
Sinus tachycardia is usually due to an increase in sympathetic activity
associated with exercise, emotion and pregnancy. Healthy young adults can
produce a rapid sinus rate, up to 200/min, during intense exercise. Sinus
tachycardia does not require treatment but sometimes may reflect an
underlying disease.
24. The management of a tachycardic patient should focus on treating the cause.
Treating the rate alone with beta-blockade in an unwell or deteriorating
patient should be done only under specialist guidance, in controlled
conditions, and when a clear evaluation of the risk–benefit ratio has been
undertaken.
The most appropriate method of rate control in AF depends primarily on the
degree of hemodynamic compromise. An intravenous loading dose of
amiodarone is well tolerated and efficacious in the majority of critically ill
patients with AF and a very rapid ventricular rate.
25. There are thromboembolic concerns regarding chemical cardioversion of AF
of unknown duration. However, in deteriorating patients, the low incidence of
embolic events makes this concern of secondary importance to achieving
hemodynamic stability.
Digoxin continues to have a role in the treatment of AF in critically unwell but
hemodynamically stable patients, when its inotropic properties can be helpful.
Electrical cardioversion is reserved for dysrhythmias with extremely high heart
rates, following failure of pharmacological management, and/or for those of
ventricular origin. It is rarely successful in dysrhythmias secondary to systemic
illness.
26. HYPOTENSION
Low BP (hypotension) should always be defined in relation to a patient’s usual BP.
The calculation of mean arterial pressure (MAP) unifies the systolic and diastolic BPs
into a single reference value. A MAP of > 65 mmHg will maintain renal perfusion in
the majority of patients, although a MAP of up to 80 mmHg may be required in
patients with chronic hypertension.
The first stage of assessment is to decide if the hypotension is physiological or
pathological.
Shock means ‘circulatory failure’. It can be defined as a level of oxygen delivery (DO2)
that fails to meet the metabolic requirements of the tissues. Hypotension is a
common presentation of shock but the terms are not synonymous.
27. Cardiogenic shock
(due to heart
problems)
Hypovolemic
shock (caused by
too little blood
volume)
Anaphylactic
shock (caused by
allergic reaction)
Septic shock (due
to infections)
Neurogenic
shock (caused by
damage to the
nervous system)
28. Along with the signs of low cardiac output, objective markers of inadequate
tissue oxygen delivery, such as increasing base deficit, elevated blood lactate
and reduced urine output, can aid early identification. If shock is suspected,
resuscitation should be commenced.
Hypotensive patients who do not have any evidence of shock are still at
significant risk of organ dysfunction. Hypotension should serve as a ‘red flag’
that there may be serious underlying pathology. Organ failure occurs despite
normal or elevated oxygen delivery, so a full assessment of the patient is
indicated. A review of the drug chart is essential, as many inpatients will be on
antihypertensive medications that are contributing to hypotension. Non-
cardiac medications may also have a negative influence on BP; for example,
some drugs used for urine outflow tract obstruction.
29. HYPERTENSION
High BP (hypertension) is common and is usually benign in a critical care
context. However, it can be the presenting feature of a number of serious
disease processes. Furthermore, acute hypertension can result in an acute rise
in vascular tone that increases left ventricular end-systolic pressure (afterload).
The left ventricle may be unable to eject blood against the increased aortic
pressure, and acute pulmonary oedema can result (referred to as ‘flash’
pulmonary edema.)
Before treating an acute rise in BP, it is worth considering a few important
diagnoses that may impact on the immediate management:
30. 1. Intracranial event. Ischemia of the brainstem (commonly via a pressure
effect) will cause acute increases in BP. A neurological examination and CT
scan of the head should be considered.
2. Fluid overload. Once the capacity of the venous blood reservoir becomes
saturated, increases in fluid volume will lead to increases in BP. This can
occur in younger patients without the onset of peripheral oedema and
originate from myocardial dysfunction or impaired renal clearance.
3. Underlying medical problems. A brief search for a history of renal disease,
spinal injury and less common metabolic causes such as
phaeochromocytoma can be worthwhile. In women of child-bearing age,
pregnancy-induced hypertension and pre-eclampsia must always be
considered.
31. 5. Primary cardiac problems. Myocardial ischemia, acute heart failure and aortic
dissection can all present with hypertension.
6. Drug-related problems. Most commonly, these involve a missed
antihypertensive medication, but sympathomimetic drugs such as cocaine
and amphetamines can be implicated.
32. DECREASED CONSCIOUS LEVEL
A reduction in conscious level should prompt an urgent assessment of the
patient, a search for the likely cause and an evaluation of the risk of airway
loss. The GCS was developed to risk-stratify head injury, but it has become the
most widely recognized assessment tool for conscious level.
Coma is defined as a persisting state of deep unconsciousness. In practice,
this means a sustained GCS of 8 or less. There are many causes of coma.
34. Moving an unconscious patient into the recovery position is best for airway
protection while preparations are made for escalation to a higher level of care.
The decision regarding intubation for airway protection is always difficult.
Length of stay in intensive care is significantly reduced if there is no
secondary organ dysfunction. Therefore, early intubation and the prevention
of lung injury constitute the safer option if there is any doubt about a
patient’s ability to protect the airway from obstruction or aspiration.
35. DECREASED URINE OUTPUT
A urine output of 0.5 mL/kg/hr is a commonly quoted, arbitrary target.
Oliguria in association with hypotension or an increase in serum creatinine
level (even if small) should prompt examination for the underlying cause.
Pre-renal causes predominate in the general inpatient population, so
optimizing the MAP by administration of intravenous fluids (and possibly
vasopressors) is the first priority.
36. In the majority of inpatients there is no role for high volumes (i.e. > 30 mL/kg)
of intravenous fluid if the MAP is normal. Exceptions to this rule include
patients with clinical dehydration or high fluid losses such as in burns,
diabetes emergencies and diabetes insipidus, where fluid management should
be guided by local protocols.
37. Abdominal compartment syndrome occurs when raised pressure within the
abdomen reduces perfusion to the abdominal organs.
It is most commonly seen in surgical patients, but can occur in medical
conditions with extreme fluid retention such as liver cirrhosis. When it is
suspected, intra-abdominal pressure can be monitored via a pressure
transducer connected to a urinary catheter (following instillation of 25 mL of
0.9% saline into the bladder).
Values over 20 mmHg suggest abdominal compartment syndrome is present.
Urgent measures should be taken to reduce the pressure, such as
decompression of the stomach, bladder and peritoneum if ascites is present. If
conservative measures fail, a laparostomy should be considered.
38. Rhabdomyolysis occurs when there is an injury to a large volume of skeletal
muscle, usually because a single limb or muscle compartment has been ischemic
for a prolonged period. It can also occur following trauma and crush injury or after
over-exertion of muscles.
Over-exertion can occur after intense physical exercise or as part of a medical
condition that causes widespread muscular activity, such as malignant
hyperpyrexia or neuroleptic malignant syndrome. A creatine kinase (CK) level of >
1000 U/L is highly suggestive, although it can rise to tens of thousands in severe
cases. Management should focus on identification and correction of the
underlying cause and support for multi-organ dysfunction. Forced alkaline diuresis
(using intravenous bicarbonate infusion and furosemide) can be used to maintain
a good flow of less acidic fluid within the renal tubules and reduce myoglobin
precipitation.