Describe tolerance as a immunologic function. What is the consequence of loss of tolerance? ( ¾ page? 2 solid paragraphs) Solution Immune tolerance is an act of self tolerance. Self tolerance could be seen against certain antigens. Tolerance is a physiological mechanism. Due to immune tolerance, the body response to an antigen either decreases or completely get eliminated. Due to this self tolerance, it leads to suppressing of allergic responses against antigens. Due to this self tolerance, the host in which the immune tolerance observed shows chronic infections instead of their elimination. Due to this self tolerance within the host, the auto reactive lymphocytes become inactivated. Within the mother due to immune-tolerance, the attack on fetuses has been severe. Due to this imbalance, leads to autoimmunity through triggering T-helper cell functioning. When the body loses its tolerance to self antigens, leads to autoimmune disorders such as thyroiditis, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus..