Depression as a factor in Rheumatoid Arthritis disease
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This document discusses a research project on the relationship between depression and rheumatoid arthritis. The hypothesis is that depression may act as an initial factor that awakens rheumatoid arthritis, an autoimmune disease. To test this, the study will compare female patients in the early stages of arthritis who have suffered from depression to similar patients who have not suffered from depression. The methodology involves questionnaires addressing different levels of depression relating to topics like financial problems, self-esteem, and relationships.
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When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/Recently uploaded (20)
Basics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different forms
Equivariant neural networks and representation theory
Equivariant neural networks and representation theory
aziz sancar nobel prize winner: from mardin to nobel
aziz sancar nobel prize winner: from mardin to nobel
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
Compexometric titration/Chelatorphy titration/chelating titration
Compexometric titration/Chelatorphy titration/chelating titration
Authoring a personal GPT for your research and practice: How we created the Q...
Authoring a personal GPT for your research and practice: How we created the Q...
Immersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths Forward
8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptx
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptx
Applied Science: Thermodynamics, Laws & Methodology.pdf
Applied Science: Thermodynamics, Laws & Methodology.pdf
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Depression as a factor in Rheumatoid Arthritis disease
- 1. by José E. Ramos BIOL 3009L RISE Program: Summer Bridge 2014
- 2. What research project will I work? Why is it important to know about this problem? How will I do this research?
- 3. Rheumatoid Arthritis It’s a systemic auto-immune disease that affects between 0.5% and 1% of the adult population worldwide.
- 5. The immune system is very complex and plays a direct role in autoimmune diseases (such as autoimmune hepatitis and rheumatoid arthritis). Structure of the immune system.
- 6. Depression Depression acts as an inflammatory disorder because the plasma levels of two cytokines are increased: i.e. interleukin-(IL)-6 tumor necrosis factor-α (TNFα) (Maes, M. 2010, )
- 8. 12-month Prevalence of Depression Among All U.S. Adults by Sex http://www.nimh.nih.gov/statistics/1MDD_ADULT.shtml
- 9. Hypothesis If depression acts as a initial factor in the patient’s rheumatoid arthritis, then it can be presumed that it awakens this auto-immunologic disease.
- 10. Group A(Experimental) Group B (Control) Female patients that have suffered from depression . Female patients that haven’t suffered from depression. Are in early stages of arthritis (40 to 45 years of age ). Are in early stages of arthritis (40 to 45 years of age). Methodology
- 11. Questions in different levels of depression from different topics (1-3). For example: Monetary problems Self esteem issues Relationship woes ( great sorrow and distress)
- 12. NIH References about reviewed concepts: http://www.niams.nih.gov/Health_Info/Rheumatic_Disease/ http://www.niaid.nih.gov/topics/immunesystem/Pages/default. aspx https://www.nimh.nih.gov/health/topics/depression/index.sht ml Spencerc, D., Covica,, T., & Tysonb, G. (2005, September 20). Depression in rheumatoid arthritis patients: demographic, clinical, and psychological predictors. . Retrieved June 21, 2014, from http://ac.els-cdn.com/S0022399905004290/1-s2.0- S0022399905004290-main.pdf?_tid=1dff0c6a-f98d-11e3-8fc1- 00000aab0f26&acdnat=1403387204_ebf20f2709a526af7a014d8b9 945890c
- 13. Maes, M. (2010, June 14). Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression. . Retrieved June 21, 2014, from http://ac.els- cdn.com/S0278584610002319/1-s2.0- S0278584610002319-main.pdf?_tid=a8343b8a- f965-11e3-a12f- 00000aacb361&acdnat=1403370256_60836a6574d2 bb5a14101bea086042a1