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According to the Nuremberg code 1947.

The voluntary consent of the human subject is absolutely essential.
This means that the person involved should have legal capacity to give consent; should be so situated as
to be able to exercise free power of choice, without the intervention of any element of force, fraud,
deceit, duress, over-reaching, or other ulterior form of constraint or coercion; and should have sufficient
knowledge and comprehension of the elements of the subject matter involved as to enable him to make
an understanding and enlightened decision.

That means that before a person would participate in a placebo control trial he must be fully informed
about the nature of trial that he is about to participate to, the future risk that he must endure and the
alternative treatments that are available outside the trial. Knowing this in mind, we cannot now
question those who chose to participate in the placebo control trial.

The experiment should be such as to yield fruitful results for the good of society, unprocurable by other
methods or means of study, and not random and unnecessary in nature
Placebo trials are use to find new treatments that could benefit the society, because even though there
are already treatments available they might not be good enough and placebo controlled trial are used to
find new effective treatments.

According to the article placebo controlled trials and the Declaration of Helsinki page 1339 paragraph 6,
Even in a straight forward placebo- controlled trial, receiving placebos does not imply receiving no
medical treatment. In most trials there will be other medications that are permitted in both treatment
groups and that are suspected to be used to a roughly similar extent. That means that the placebo group
in this trial is not totally denied of medications.

According again to this article page 1340 paragraph 3, there are areas of medicine were reliable
evidence of efficacy can only be generated by placebo controlled trials.


The advancement of a new drug being tested is not only measured with its efficacy because if that is the
case, if there is no substantial evidence of efficacy of a new drug, it could lead to a less reliable clinical
conclusion but with Placebo-controlled trial, it doesn’t only show the effectiveness of a new drug but
also the advancement of it compared to the licensed drug in other areas other than efficacy.

So all in all, this is why we are pro-placebo controlled trial.

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Debate1

  • 1. According to the Nuremberg code 1947. The voluntary consent of the human subject is absolutely essential. This means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, deceit, duress, over-reaching, or other ulterior form of constraint or coercion; and should have sufficient knowledge and comprehension of the elements of the subject matter involved as to enable him to make an understanding and enlightened decision. That means that before a person would participate in a placebo control trial he must be fully informed about the nature of trial that he is about to participate to, the future risk that he must endure and the alternative treatments that are available outside the trial. Knowing this in mind, we cannot now question those who chose to participate in the placebo control trial. The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature Placebo trials are use to find new treatments that could benefit the society, because even though there are already treatments available they might not be good enough and placebo controlled trial are used to find new effective treatments. According to the article placebo controlled trials and the Declaration of Helsinki page 1339 paragraph 6, Even in a straight forward placebo- controlled trial, receiving placebos does not imply receiving no medical treatment. In most trials there will be other medications that are permitted in both treatment groups and that are suspected to be used to a roughly similar extent. That means that the placebo group in this trial is not totally denied of medications. According again to this article page 1340 paragraph 3, there are areas of medicine were reliable evidence of efficacy can only be generated by placebo controlled trials. The advancement of a new drug being tested is not only measured with its efficacy because if that is the case, if there is no substantial evidence of efficacy of a new drug, it could lead to a less reliable clinical conclusion but with Placebo-controlled trial, it doesn’t only show the effectiveness of a new drug but also the advancement of it compared to the licensed drug in other areas other than efficacy. So all in all, this is why we are pro-placebo controlled trial.