This document discusses the challenges of teaching science to adolescent learners in the 21st century. It examines the cognitive abilities of adolescents across five domains: adaptability, complex communication/social skills, non-routine problem-solving skills, self-management/self-development, and systems thinking. The document argues that adolescent learners face unique challenges compared to younger students due to their cognitive development. It recommends that science education be tailored to capitalize on adolescents' abilities while addressing the constraints of their stage of development.