Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model
•Download as PPTX, PDF•
0 likes•31 views
This was an evaluation of a study I presented in my seminar class for my major. Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model
Report
Share
Report
Share
Recommended
Seven Seas Jointcare
Osteoarthritis is a disorder of movable joints characterized by cartilage degeneration and joint damage. Risk factors include age, genetics, obesity, injury, and repetitive joint use. Glucosamine and chondroitin help rebuild cartilage as key components of cartilage tissue. Omega-3 fatty acids reduce inflammation and slow cartilage breakdown. Seven Seas JointCare products combine these ingredients to support joint health, with options for mild, moderate, or severe osteoarthritis providing different levels of glucosamine, chondroitin, collagen, and omega-3.
Delayed onset muscle soreness: Relief by topical natural phytochemicals
Delayed onset muscle soreness (DOMS) is caused by microscopic damage to muscle fibers following unaccustomed exercise. It causes pain and stiffness in the hours to days after exercise. The document discusses the inflammatory process underlying DOMS and how certain phytochemicals found in foods and herbs may help relieve symptoms by targeting inflammatory mediators. A clinical study showed that a topical formula containing phytochemical extracts from spices and herbs effectively reduced pain and swelling in patients with muscle injuries like strains or sprains.
24 muscle damage sr2002 2013 aj
A single bout of unaccustomed eccentric exercise can cause muscle damage symptoms like delayed onset muscle soreness and reduced force production. Muscle damage may be caused by mechanical disruption of muscle fibers during eccentric contractions as well as temperature and metabolic changes. Markers of muscle damage include increased blood levels of creatine kinase and myoglobin proteins as well as structural damage seen microscopically. Repeated bouts of eccentric exercise reduce the muscle damaging effects through an adaptation known as the repeated bout effect.
Poster_Jan
1) Skeletal muscles are essential for locomotion, breathing, posture and speaking. They also store protein reserves that can be mobilized during stress.
2) A co-culture model of rat embryonic spinal cord and human skeletal muscle cells allows the study of neuromuscular junction formation and muscle contraction in vitro. This model replicates muscle fiber differentiation and development of functional contractile apparatus through innervation.
3) Various studies have examined the effects of drugs on muscle development, innervation and stress response using this model. One study showed that dexamethasone impaired innervation while agrin promoted it. Another found that agrin increased secretion of interleukin-6, which influences muscle development.
Dawo_Sallu_RP
This study investigated the effects of timing of omega-3 supplementation on reducing delayed-onset muscle soreness (DOMS) following resistance exercise. Twelve males were randomly assigned to supplement with omega-3 either before (PRE-EX) or after (POST-EX) a heavy resistance exercise protocol designed to induce muscle damage. Assessments of muscle soreness, strength loss, swelling and range of motion were performed at various time points up to 96 hours post-exercise. Preliminary results found that PRE-EX supplementation showed lower muscle soreness ratings and a trend for less swelling compared to POST-EX, suggesting omega-3 may be more effective at reducing DOMS symptoms when taken before exercise.
The human body the muscular system
Human movement is dependent upon the integrated activity of many different systems, however, the driving force behind this is the muscular system.
Within the muscular system muscles work to create forces across joints and cause movement.
Soprts 1
This document discusses muscular control of movement and summarizes the structure and function of skeletal muscles. It describes the types of muscles in the body, including skeletal muscles which allow for voluntary movement. Skeletal muscles are composed of fascicles, fibers, and myofibrils. Contraction occurs via the sliding filament theory when calcium binds to troponin, allowing myosin heads to bind actin and generate force through a power stroke. Recruitment of motor units and fiber types determines the force and endurance of muscle contractions. Factors like nutrition, training, genetics influence muscle development.
JCI
This study investigated protein breakdown in skeletal muscles of diabetic rats. The researchers found:
1) Muscle extracts from diabetic rats contained greater amounts of ubiquitinated proteins and had 40-50% higher rates of ubiquitin conjugation compared to controls.
2) The increased ubiquitination in diabetic muscles occurred mainly through the N-end rule pathway involving E2 14k and E3α enzymes.
3) mRNA levels of E2 14k and E3α were elevated 2-fold in diabetic muscles, although protein levels were not significantly changed.
4) The results suggest that small increases in both E2 14k and E3α enzymes in diabetic muscles accelerates ubiquitin conjugation and protein breakdown
Recommended
Seven Seas Jointcare
Osteoarthritis is a disorder of movable joints characterized by cartilage degeneration and joint damage. Risk factors include age, genetics, obesity, injury, and repetitive joint use. Glucosamine and chondroitin help rebuild cartilage as key components of cartilage tissue. Omega-3 fatty acids reduce inflammation and slow cartilage breakdown. Seven Seas JointCare products combine these ingredients to support joint health, with options for mild, moderate, or severe osteoarthritis providing different levels of glucosamine, chondroitin, collagen, and omega-3.
Delayed onset muscle soreness: Relief by topical natural phytochemicals
Delayed onset muscle soreness (DOMS) is caused by microscopic damage to muscle fibers following unaccustomed exercise. It causes pain and stiffness in the hours to days after exercise. The document discusses the inflammatory process underlying DOMS and how certain phytochemicals found in foods and herbs may help relieve symptoms by targeting inflammatory mediators. A clinical study showed that a topical formula containing phytochemical extracts from spices and herbs effectively reduced pain and swelling in patients with muscle injuries like strains or sprains.
24 muscle damage sr2002 2013 aj
A single bout of unaccustomed eccentric exercise can cause muscle damage symptoms like delayed onset muscle soreness and reduced force production. Muscle damage may be caused by mechanical disruption of muscle fibers during eccentric contractions as well as temperature and metabolic changes. Markers of muscle damage include increased blood levels of creatine kinase and myoglobin proteins as well as structural damage seen microscopically. Repeated bouts of eccentric exercise reduce the muscle damaging effects through an adaptation known as the repeated bout effect.
Poster_Jan
1) Skeletal muscles are essential for locomotion, breathing, posture and speaking. They also store protein reserves that can be mobilized during stress.
2) A co-culture model of rat embryonic spinal cord and human skeletal muscle cells allows the study of neuromuscular junction formation and muscle contraction in vitro. This model replicates muscle fiber differentiation and development of functional contractile apparatus through innervation.
3) Various studies have examined the effects of drugs on muscle development, innervation and stress response using this model. One study showed that dexamethasone impaired innervation while agrin promoted it. Another found that agrin increased secretion of interleukin-6, which influences muscle development.
Dawo_Sallu_RP
This study investigated the effects of timing of omega-3 supplementation on reducing delayed-onset muscle soreness (DOMS) following resistance exercise. Twelve males were randomly assigned to supplement with omega-3 either before (PRE-EX) or after (POST-EX) a heavy resistance exercise protocol designed to induce muscle damage. Assessments of muscle soreness, strength loss, swelling and range of motion were performed at various time points up to 96 hours post-exercise. Preliminary results found that PRE-EX supplementation showed lower muscle soreness ratings and a trend for less swelling compared to POST-EX, suggesting omega-3 may be more effective at reducing DOMS symptoms when taken before exercise.
The human body the muscular system
Human movement is dependent upon the integrated activity of many different systems, however, the driving force behind this is the muscular system.
Within the muscular system muscles work to create forces across joints and cause movement.
Soprts 1
This document discusses muscular control of movement and summarizes the structure and function of skeletal muscles. It describes the types of muscles in the body, including skeletal muscles which allow for voluntary movement. Skeletal muscles are composed of fascicles, fibers, and myofibrils. Contraction occurs via the sliding filament theory when calcium binds to troponin, allowing myosin heads to bind actin and generate force through a power stroke. Recruitment of motor units and fiber types determines the force and endurance of muscle contractions. Factors like nutrition, training, genetics influence muscle development.
JCI
This study investigated protein breakdown in skeletal muscles of diabetic rats. The researchers found:
1) Muscle extracts from diabetic rats contained greater amounts of ubiquitinated proteins and had 40-50% higher rates of ubiquitin conjugation compared to controls.
2) The increased ubiquitination in diabetic muscles occurred mainly through the N-end rule pathway involving E2 14k and E3α enzymes.
3) mRNA levels of E2 14k and E3α were elevated 2-fold in diabetic muscles, although protein levels were not significantly changed.
4) The results suggest that small increases in both E2 14k and E3α enzymes in diabetic muscles accelerates ubiquitin conjugation and protein breakdown
Isotonic & isometric contraction
1) Muscle contraction requires energy supplied by ATP, which is generated through several metabolic pathways in the muscle cell, including phosphocreatine, glycogen breakdown, and oxidative metabolism.
2) As muscle contracts, it produces heat from various sources like activation, shortening, maintenance, relaxation, and recovery.
3) The different metabolic pathways sustain muscle contraction for varying durations, with phosphocreatine and glycolysis sustaining maximal contraction for only a few seconds to a minute, while oxidative metabolism provides energy for sustained, long-term contraction.
Strong Jointz Supplement
Muscle NutrientzTM Jointz PowerTM assists in maintaining strong, healthy, flexible joints, in addition to benefiting hair, skin and nails! Why suffer the workout burn, or the stiffness of arthritis and debilitating pain? Order the MADE IN THE USA Muscle NutrientzTM Jointz PowerTM today and reap the benefits!
Chapter 7
This document discusses key concepts related to strength training including definitions of strength training, sarcopenia, activities of daily living, and one repetition maximum. It also summarizes the benefits of strength training, differences between muscular strength and endurance, types of muscle fibers, overload principle, and specificity of training. The main principles of strength training are also defined as mode, resistance, sets, frequency, and volume.
muscle contraction
Muscle contraction occurs when the protein filaments actin and myosin slide over one another, generating tension within muscle fibers. Muscle fatigue results from vigorous exercise and prevents the normal stages of muscle contraction from occurring. Fatigue is a feeling of tiredness that causes a need to rest due to a lack of energy or strength, which can be caused by overwork, poor sleep, worry, or lack of exercise.
Aerobics exercise for healthy adult
This document outlines an aerobics exercise program for healthy adults. It includes an introduction to aerobics, concepts like fitness and cardiovascular adaptation, principles of exercise like intensity and duration, physiological responses, and components of an exercise program including warm-up, aerobic exercise, and cool-down periods. The goal is to improve all elements of fitness through rhythmic aerobic exercise combined with stretching and strength training performed 3 times per week for 20-30 minutes.
Anti inflammatory-and-anti-arthritic-efficacy-and-safety-of-purified-shilajit...
Abstract
The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion). Serum samples collected from these dogs were examined each month for biomarkers of liver (bilirubin, ALT, and AST), kidney (BUN and creatinine) heart and muscle (creatine kinase) functions. The findings of this study revealed that dogs receiving Shilajit (Group-II) showed a significant (P< 0.05) reduction in pain from limb manipulation by day 60, and overall pain and pain after physical exertion by day 120. Maximum pain reduction, using all three criteria, was observed on day 150. Pain level remained significantly unchanged in dogs receiving the placebo. Dogs in either group showed no significant change (P>0.05) in physical parameters or serum markers, suggesting that Shilajit was well tolerated by moderately arthritic dogs. It was concluded that Shilajit significantly (P< 0.05) reduced pain in osteoarthritic dogs and markedly improved their daily life without any side effects.
Keywords: Purified Shilajit; Osteoarthritis in canine; Shilajit safety; Anti-arthritic nutraceutical
Chapter 7
Strength training provides several benefits and should be practiced by everyone, not just athletes. It improves muscular strength and endurance through progressive overload exercises. Key principles include using sufficient resistance (80% of 1RM) and applying the overload principle by gradually increasing weight, reps, sets or decreasing rest periods. Strength is also affected by neural factors like motor unit recruitment and muscle fiber type, as well as training specificity. Regular strength training can help prevent age-related muscle loss and improve functional ability.
Bigfour
Describes the four components necessary in an exercise program: strength, flexibility, endurance and balance.
Dr Q's PainX
Dr. Q's PainEx is a supplement formulated to support the body's normal response to inflammation and provide relief for joint discomfort. It contains standardized extracts of white willow bark, Boswellia serrata, and a proprietary berry blend. Willow bark contains salicin, which supports cytokine balance and relieves discomfort. Boswellia serrata extract contains boswellic acids that may inhibit the 5-lipoxygenase enzyme. The berry blend provides antioxidants to support tissues. A clinical study found the Boswellia extract significantly reduced knee discomfort and improved function.
Chapter 7
NASM Integrated Flexibility Continuum
Corrective Flexibility: This phase is designed to correct common postural dysfunctions, muscle imbalances, and joint dysfunction. It includes: SMR and static stretching (and neuromuscular stretching if trained in technique). ... This includes SMR and dynamic stretching.
Muscular physiology artifact
This document discusses various topics related to muscular physiology, including:
1. The roles of skeletal muscle in providing movement, heat, and posture.
2. The similarities between muscle and nerve excitability.
3. The unique structures of skeletal muscle fibers involved in contractility and excitability.
4. How the structure of myofilaments relates to their function in muscle contraction.
Anti arthritic-efficacy-and-safety-of-crominex-3+(trivalent-chromium-phyllant...
Abstract
The present investigation was undertaken to evaluate the therapeutic efficacy and safety of Crominex® 3+ (a complex of trivalent chromium, Phyllanthus emblica (Amla) extract and purified Shilajit) in moderately arthritic dogs. Eleven client-owned moderately arthritic dogs in a randomized double-blinded study received placebo or Crominex® 3+ twice daily for a period of 150 days. On a monthly basis, each dog was evaluated for arthritis associated pain (overall pain, pain upon limb manipulation and pain after physical exertion) and a full physical exam (body weight, body temperature and heart rate). At the same time intervals, dogs serum samples were examined for biomarkers of kidney (BUN and creatinine), liver (bilirubin, ALT and AST) and heart and skeletal muscle (CK) functions. Findings of this investigation revealed that dogs receiving Crominex® 3+ (1000 μg chromium, 15 mg Amla extract and 15 mg purified Shilajit per day in two divided doses) exhibited a significant (P< 0.05) reduction in arthritic pain noted as early as after 90 days with a maximum reduction after 150 days of treatment. Pain level remained the same or slightly increased in the dogs receiving placebo. No significant change occurred in physical parameters or serum biomarkers in dogs on placebo or Crominex® 3+, which suggested that Crominex® 3+ was well tolerated by arthritic dogs. In conclusion, Crominex® 3+ significantly (P< 0.05) ameliorated arthritic pain and improved quality of life without causing any untoward effects in moderately arthritic dogs.
ortho 04 drugs in orthopaedic (principle & common use)
The document provides an overview of common drug usage in orthopedic practice, including analgesics, muscle relaxants, anti-inflammatory drugs, and drugs for osteoarthritis and osteoporosis management. It discusses drug classes, mechanisms of action, indications, dosages, side effects and considerations for safe usage. The goal is to refresh principles for medical students on properly using these medications.
Role of drugs in orthodontics
This document discusses various drugs used in orthodontics, including their mechanisms of action and effects. It covers prostaglandins and leukotrienes, which are involved in inflammation and tooth movement. Non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and diclofenac are described as well as their analgesic, antipyretic and anti-inflammatory properties from inhibiting prostaglandin synthesis. Preferential COX-2 inhibitors and specific drugs like nimesulide and meloxicam are also summarized.
L'idrossitirosolo è in grado di proteggere e aumentare l'attività dei mitocon...
L'idrossitirosolo, un polifenolo estratto dalle olive, attraverso una protezione dei mitocondri, le centrali energetiche della cellula, è in grado di aumentare la resistenza muscolare negli animali da esperimento
Myoguide guidance-white-paper-v17
The focus of this White Paper will be on defining trigger points and their role in pathology. Myofascial
pain may be categorized in many ways, but the majority of cases are associated with trigger points. It is
important to continue to consider other sources, such as, muscle spasm, muscle tension, and muscle deficiency
Osteoarthritis with Naturopathic Medicine
Addressing Osteoarthritis with Naturopathy and Holistic approaches. Also includes a reveiw of conventional treatment options. Presentation by Adam Rinde, ND, a Naturopath based in Kirkland, Washington.
Lion's Mane Mushroom: Benefits for Athletes and Active Individuals
In the realm of health and wellness, the exploration of natural remedies and supplements continues to captivate both researchers and enthusiasts alike. Among these, Lion's Mane Mushroom (Hericium erinaceus) stands out as a fascinating subject of study, renowned for its purported health benefits, particularly in the realm of physical performance.
This presentation delves into the intriguing potential of Lion's Mane Mushroom in enhancing muscular endurance and reducing fatigue, offering insights into its mechanisms of action and practical implications for athletes and active individuals.
The journey begins with an introduction to Lion's Mane Mushroom, tracing its traditional use and the recent surge in scientific interest surrounding its medicinal properties. From there, we embark on a deep dive into the importance of muscular endurance, laying the foundation for understanding how Lion's Mane Mushroom could play a pivotal role in optimizing athletic performance and daily activities.
Exploring the mechanisms of action, we uncover the multifaceted ways in which Lion's Mane Mushroom may exert its beneficial effects. From stimulating Nerve Growth Factor (NGF) production to harnessing its anti-inflammatory and antioxidant properties, Lion's Mane Mushroom emerges as a holistic ally in supporting nerve health, reducing inflammation, and combating oxidative stress—key contributors to muscular fatigue and impaired performance.
Moreover, we unravel the fascinating potential of Lion's Mane Mushroom in optimizing oxygen utilization, enhancing energy metabolism, and facilitating ATP synthesis—fundamental processes that underpin muscular function and endurance during physical exertion.
Drawing upon existing research and clinical evidence, we present a nuanced perspective on the efficacy of Lion's Mane Mushroom, shedding light on notable studies and findings while acknowledging the need for further exploration and validation.
As we transition to practical applications, we provide actionable insights into incorporating Lion's Mane Mushroom into fitness regimens, offering considerations for dosage, timing, and supplementation strategies to maximize its benefits effectively.
In conclusion, this presentation serves as a comprehensive exploration of the transformative potential of Lion's Mane Mushroom in the realm of physical performance. By unraveling its mechanisms of action and practical implications, we invite both researchers and enthusiasts to embark on a journey of discovery, unlocking the profound benefits that this remarkable fungus has to offer in enhancing muscular endurance and reducing fatigue.
Join us as we delve deeper into the world of natural remedies and harness the power of Lion's Mane Mushroom to elevate your performance and well-being to new heights.
Short inter-set rest blunts resistance exercise-induced
Manipulating the rest-recovery interval between sets of resistance exercise may influence
training-induced muscle remodelling. The aim of this study was to determine the acute muscle
anabolic response to resistance exercise performed with short or long inter-set rest intervals.
In a study with a parallel-group design, 16 males completed four sets of bilateral leg-press and
knee-extension exercise at 75% of one-repetition maximum to momentary muscular failure,
followed by ingestion of 25 g of whey protein. Resistance exercise sets were interspersed by
1 min (n = 8) or 5 min of passive rest (n = 8). Muscle biopsies were obtained at rest, 0, 4, 24
and 28 h postexercise during a primed continuous infusion of l-[ring-13C6]phenylalanine to
determine myofibrillar protein synthesis and intracellular signalling.
Physiotherapist in Kolkata
Physiotherapy includes scientific techniques such as oil massage and various exercises that encourages the body to heal itself. Physiotherapist in Kolkata offers various techniques for patients injured from sports, muscle pain, accidents etc.
Knee osteoarthritis treatment in 2019
This document discusses treatment strategies for knee osteoarthritis, including regenerative therapy using mesenchymal stem cells (MSCs). It notes that while MSCs have properties making them preferable for osteoarthritis treatment, including ease of accessibility, anti-inflammatory effects, safety, and differentiation abilities, some studies have found MSCs reduce pain but not degenerative changes. Multiple injections of allogeneic bone marrow MSCs may be important to modulate the osteoarthritis joint environment and restore lost cells. Future developments hoped for include generation of commercial stem cell products at a reasonable cost.
More Related Content
What's hot
Isotonic & isometric contraction
1) Muscle contraction requires energy supplied by ATP, which is generated through several metabolic pathways in the muscle cell, including phosphocreatine, glycogen breakdown, and oxidative metabolism.
2) As muscle contracts, it produces heat from various sources like activation, shortening, maintenance, relaxation, and recovery.
3) The different metabolic pathways sustain muscle contraction for varying durations, with phosphocreatine and glycolysis sustaining maximal contraction for only a few seconds to a minute, while oxidative metabolism provides energy for sustained, long-term contraction.
Strong Jointz Supplement
Muscle NutrientzTM Jointz PowerTM assists in maintaining strong, healthy, flexible joints, in addition to benefiting hair, skin and nails! Why suffer the workout burn, or the stiffness of arthritis and debilitating pain? Order the MADE IN THE USA Muscle NutrientzTM Jointz PowerTM today and reap the benefits!
Chapter 7
This document discusses key concepts related to strength training including definitions of strength training, sarcopenia, activities of daily living, and one repetition maximum. It also summarizes the benefits of strength training, differences between muscular strength and endurance, types of muscle fibers, overload principle, and specificity of training. The main principles of strength training are also defined as mode, resistance, sets, frequency, and volume.
muscle contraction
Muscle contraction occurs when the protein filaments actin and myosin slide over one another, generating tension within muscle fibers. Muscle fatigue results from vigorous exercise and prevents the normal stages of muscle contraction from occurring. Fatigue is a feeling of tiredness that causes a need to rest due to a lack of energy or strength, which can be caused by overwork, poor sleep, worry, or lack of exercise.
Aerobics exercise for healthy adult
This document outlines an aerobics exercise program for healthy adults. It includes an introduction to aerobics, concepts like fitness and cardiovascular adaptation, principles of exercise like intensity and duration, physiological responses, and components of an exercise program including warm-up, aerobic exercise, and cool-down periods. The goal is to improve all elements of fitness through rhythmic aerobic exercise combined with stretching and strength training performed 3 times per week for 20-30 minutes.
Anti inflammatory-and-anti-arthritic-efficacy-and-safety-of-purified-shilajit...
Abstract
The objective of this investigation was to evaluate the efficacy and safety of purified Shilajit in moderately arthritic dogs. Ten client-owned dogs in a randomized double-blinded study received either a placebo or Shilajit (500 mg) twice daily for a period of five months. Dogs were evaluated each month for physical condition (body weight, body temperature, heart rate, and respiration rate) and pain associated with arthritis (overall pain, pain from limb manipulation, and pain after physical exertion). Serum samples collected from these dogs were examined each month for biomarkers of liver (bilirubin, ALT, and AST), kidney (BUN and creatinine) heart and muscle (creatine kinase) functions. The findings of this study revealed that dogs receiving Shilajit (Group-II) showed a significant (P< 0.05) reduction in pain from limb manipulation by day 60, and overall pain and pain after physical exertion by day 120. Maximum pain reduction, using all three criteria, was observed on day 150. Pain level remained significantly unchanged in dogs receiving the placebo. Dogs in either group showed no significant change (P>0.05) in physical parameters or serum markers, suggesting that Shilajit was well tolerated by moderately arthritic dogs. It was concluded that Shilajit significantly (P< 0.05) reduced pain in osteoarthritic dogs and markedly improved their daily life without any side effects.
Keywords: Purified Shilajit; Osteoarthritis in canine; Shilajit safety; Anti-arthritic nutraceutical
Chapter 7
Strength training provides several benefits and should be practiced by everyone, not just athletes. It improves muscular strength and endurance through progressive overload exercises. Key principles include using sufficient resistance (80% of 1RM) and applying the overload principle by gradually increasing weight, reps, sets or decreasing rest periods. Strength is also affected by neural factors like motor unit recruitment and muscle fiber type, as well as training specificity. Regular strength training can help prevent age-related muscle loss and improve functional ability.
Bigfour
Describes the four components necessary in an exercise program: strength, flexibility, endurance and balance.
Dr Q's PainX
Dr. Q's PainEx is a supplement formulated to support the body's normal response to inflammation and provide relief for joint discomfort. It contains standardized extracts of white willow bark, Boswellia serrata, and a proprietary berry blend. Willow bark contains salicin, which supports cytokine balance and relieves discomfort. Boswellia serrata extract contains boswellic acids that may inhibit the 5-lipoxygenase enzyme. The berry blend provides antioxidants to support tissues. A clinical study found the Boswellia extract significantly reduced knee discomfort and improved function.
Chapter 7
NASM Integrated Flexibility Continuum
Corrective Flexibility: This phase is designed to correct common postural dysfunctions, muscle imbalances, and joint dysfunction. It includes: SMR and static stretching (and neuromuscular stretching if trained in technique). ... This includes SMR and dynamic stretching.
Muscular physiology artifact
This document discusses various topics related to muscular physiology, including:
1. The roles of skeletal muscle in providing movement, heat, and posture.
2. The similarities between muscle and nerve excitability.
3. The unique structures of skeletal muscle fibers involved in contractility and excitability.
4. How the structure of myofilaments relates to their function in muscle contraction.
Anti arthritic-efficacy-and-safety-of-crominex-3+(trivalent-chromium-phyllant...
Abstract
The present investigation was undertaken to evaluate the therapeutic efficacy and safety of Crominex® 3+ (a complex of trivalent chromium, Phyllanthus emblica (Amla) extract and purified Shilajit) in moderately arthritic dogs. Eleven client-owned moderately arthritic dogs in a randomized double-blinded study received placebo or Crominex® 3+ twice daily for a period of 150 days. On a monthly basis, each dog was evaluated for arthritis associated pain (overall pain, pain upon limb manipulation and pain after physical exertion) and a full physical exam (body weight, body temperature and heart rate). At the same time intervals, dogs serum samples were examined for biomarkers of kidney (BUN and creatinine), liver (bilirubin, ALT and AST) and heart and skeletal muscle (CK) functions. Findings of this investigation revealed that dogs receiving Crominex® 3+ (1000 μg chromium, 15 mg Amla extract and 15 mg purified Shilajit per day in two divided doses) exhibited a significant (P< 0.05) reduction in arthritic pain noted as early as after 90 days with a maximum reduction after 150 days of treatment. Pain level remained the same or slightly increased in the dogs receiving placebo. No significant change occurred in physical parameters or serum biomarkers in dogs on placebo or Crominex® 3+, which suggested that Crominex® 3+ was well tolerated by arthritic dogs. In conclusion, Crominex® 3+ significantly (P< 0.05) ameliorated arthritic pain and improved quality of life without causing any untoward effects in moderately arthritic dogs.
What's hot (12)
Anti inflammatory-and-anti-arthritic-efficacy-and-safety-of-purified-shilajit...
Anti inflammatory-and-anti-arthritic-efficacy-and-safety-of-purified-shilajit...
Anti arthritic-efficacy-and-safety-of-crominex-3+(trivalent-chromium-phyllant...
Anti arthritic-efficacy-and-safety-of-crominex-3+(trivalent-chromium-phyllant...
Similar to Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model
ortho 04 drugs in orthopaedic (principle & common use)
The document provides an overview of common drug usage in orthopedic practice, including analgesics, muscle relaxants, anti-inflammatory drugs, and drugs for osteoarthritis and osteoporosis management. It discusses drug classes, mechanisms of action, indications, dosages, side effects and considerations for safe usage. The goal is to refresh principles for medical students on properly using these medications.
Role of drugs in orthodontics
This document discusses various drugs used in orthodontics, including their mechanisms of action and effects. It covers prostaglandins and leukotrienes, which are involved in inflammation and tooth movement. Non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and diclofenac are described as well as their analgesic, antipyretic and anti-inflammatory properties from inhibiting prostaglandin synthesis. Preferential COX-2 inhibitors and specific drugs like nimesulide and meloxicam are also summarized.
L'idrossitirosolo è in grado di proteggere e aumentare l'attività dei mitocon...
L'idrossitirosolo, un polifenolo estratto dalle olive, attraverso una protezione dei mitocondri, le centrali energetiche della cellula, è in grado di aumentare la resistenza muscolare negli animali da esperimento
Myoguide guidance-white-paper-v17
The focus of this White Paper will be on defining trigger points and their role in pathology. Myofascial
pain may be categorized in many ways, but the majority of cases are associated with trigger points. It is
important to continue to consider other sources, such as, muscle spasm, muscle tension, and muscle deficiency
Osteoarthritis with Naturopathic Medicine
Addressing Osteoarthritis with Naturopathy and Holistic approaches. Also includes a reveiw of conventional treatment options. Presentation by Adam Rinde, ND, a Naturopath based in Kirkland, Washington.
Lion's Mane Mushroom: Benefits for Athletes and Active Individuals
In the realm of health and wellness, the exploration of natural remedies and supplements continues to captivate both researchers and enthusiasts alike. Among these, Lion's Mane Mushroom (Hericium erinaceus) stands out as a fascinating subject of study, renowned for its purported health benefits, particularly in the realm of physical performance.
This presentation delves into the intriguing potential of Lion's Mane Mushroom in enhancing muscular endurance and reducing fatigue, offering insights into its mechanisms of action and practical implications for athletes and active individuals.
The journey begins with an introduction to Lion's Mane Mushroom, tracing its traditional use and the recent surge in scientific interest surrounding its medicinal properties. From there, we embark on a deep dive into the importance of muscular endurance, laying the foundation for understanding how Lion's Mane Mushroom could play a pivotal role in optimizing athletic performance and daily activities.
Exploring the mechanisms of action, we uncover the multifaceted ways in which Lion's Mane Mushroom may exert its beneficial effects. From stimulating Nerve Growth Factor (NGF) production to harnessing its anti-inflammatory and antioxidant properties, Lion's Mane Mushroom emerges as a holistic ally in supporting nerve health, reducing inflammation, and combating oxidative stress—key contributors to muscular fatigue and impaired performance.
Moreover, we unravel the fascinating potential of Lion's Mane Mushroom in optimizing oxygen utilization, enhancing energy metabolism, and facilitating ATP synthesis—fundamental processes that underpin muscular function and endurance during physical exertion.
Drawing upon existing research and clinical evidence, we present a nuanced perspective on the efficacy of Lion's Mane Mushroom, shedding light on notable studies and findings while acknowledging the need for further exploration and validation.
As we transition to practical applications, we provide actionable insights into incorporating Lion's Mane Mushroom into fitness regimens, offering considerations for dosage, timing, and supplementation strategies to maximize its benefits effectively.
In conclusion, this presentation serves as a comprehensive exploration of the transformative potential of Lion's Mane Mushroom in the realm of physical performance. By unraveling its mechanisms of action and practical implications, we invite both researchers and enthusiasts to embark on a journey of discovery, unlocking the profound benefits that this remarkable fungus has to offer in enhancing muscular endurance and reducing fatigue.
Join us as we delve deeper into the world of natural remedies and harness the power of Lion's Mane Mushroom to elevate your performance and well-being to new heights.
Short inter-set rest blunts resistance exercise-induced
Manipulating the rest-recovery interval between sets of resistance exercise may influence
training-induced muscle remodelling. The aim of this study was to determine the acute muscle
anabolic response to resistance exercise performed with short or long inter-set rest intervals.
In a study with a parallel-group design, 16 males completed four sets of bilateral leg-press and
knee-extension exercise at 75% of one-repetition maximum to momentary muscular failure,
followed by ingestion of 25 g of whey protein. Resistance exercise sets were interspersed by
1 min (n = 8) or 5 min of passive rest (n = 8). Muscle biopsies were obtained at rest, 0, 4, 24
and 28 h postexercise during a primed continuous infusion of l-[ring-13C6]phenylalanine to
determine myofibrillar protein synthesis and intracellular signalling.
Physiotherapist in Kolkata
Physiotherapy includes scientific techniques such as oil massage and various exercises that encourages the body to heal itself. Physiotherapist in Kolkata offers various techniques for patients injured from sports, muscle pain, accidents etc.
Knee osteoarthritis treatment in 2019
This document discusses treatment strategies for knee osteoarthritis, including regenerative therapy using mesenchymal stem cells (MSCs). It notes that while MSCs have properties making them preferable for osteoarthritis treatment, including ease of accessibility, anti-inflammatory effects, safety, and differentiation abilities, some studies have found MSCs reduce pain but not degenerative changes. Multiple injections of allogeneic bone marrow MSCs may be important to modulate the osteoarthritis joint environment and restore lost cells. Future developments hoped for include generation of commercial stem cell products at a reasonable cost.
Dr Q Vitamins - NitroMax
Nitric oxide (NO) is produced in the body from L-arginine and plays important roles in regulating organs and blood flow. L-arginine and L-citrulline support NO production, while antioxidants like vitamins C and E help maintain NO levels. Dr Qs NitroMax contains these ingredients like L-arginine, L-citrulline, quercetin and folate to support healthy NO levels, which is important for circulation, immune function and other bodily processes. The formula is designed to optimize blood flow, support male sexual function, lean body mass and brain health.
Dissertation
Effects of dietary nitrate on responses to sub-maximal running and time-trial performance following exercise-induced muscle damage
Bisphosphonate Therapy in Horses
This document summarizes research on bisphosphonate therapy for treating navicular disease in horses. Bisphosphonates were originally developed as industrial chemicals but are now used medically to treat bone disorders in humans. Two bisphosphonates, tiludronate and clodronate, have been approved for treating navicular disease in horses. Clinical studies on these drugs found they may reduce lameness when combined with corrective shoeing, though their exact mechanism of action in horses is still unknown. Potential side effects seen in some horses include transient colic and injection site reactions. More research is needed on their long-term safety profile and efficacy, especially in young horses.
HerboJoint | Joint Pain Relief Cream | Herbal
HerboJoint is a medicinal cream for all types of Joint Pain. The product of Bordoloi Biotech India Pvt Ltd is a carefully developed cream with extensive Research and Development and is a fully tested cream with all the characterization work carried out at well-established Institutions in India.
HerboJoint is a non-greasy cream which gives no irritation upon application. Being a water based natural cream, it doesn’t leave any residue for any stain as well. The cream works on all type of Joint Pain but shows significant signs of improvement for users suffering from Osteoarthritis (OA) and Rheumatoid Arthritis (RA). www.herbojoint.com
Be Your Own Health Expert - Osteoarthritis
Learn the difference between “osteoporosis,” “osteoarthrosis,” and “osteoarthritis,” and how to manage inflammation in the joints with diet and exercise.
Osteoporosis ppt
This presentation discusses osteoporosis and bone remodeling. It defines osteoporosis and describes the categories. It then summarizes the six step process of bone remodeling, including the roles of osteoclasts and osteoblasts in resorbing and rebuilding bone. Estrogen's positive effects on this process are noted. The document also outlines the pathophysiology, diagnosis, and pharmacological and non-pharmacological treatment options for osteoporosis.
bone spur treatment
Bone spurs are abnormal bone growths that most commonly occur in joints, where two or more bones meet. They form as the body attempts to repair damage to cartilage from conditions like osteoarthritis. Common symptoms include pain, swelling, and pressure on nearby tissues over time. Non-surgical treatment options include medications, physical therapy, exercises, and injections to reduce inflammation and pain. Surgery to remove bone spurs may be necessary if non-surgical methods fail or if the bone spurs are pressing on nerves or the spinal cord, causing persistent pain or motor loss.
Achilles tendinopathy
This document provides information about Achilles tendinopathy, including:
- It is a common overuse injury among athletes and the general public.
- It can be classified based on its location as insertional, non-insertional, or proximal tendinopathy.
- Risk factors include excessive loading, tight calf muscles, foot abnormalities, and medical issues.
- Diagnosis involves physical exams like the Arc sign and imaging like ultrasound or MRI.
- Treatment begins with rest, bracing, eccentric exercises, and other conservative methods, with surgery reserved for severe cases.
Exercise Treatment Of The Obese Patient
The document discusses exercise and its benefits for obese patients. It defines different types of physical activity and exercise. It describes the physiological effects of exercise on skeletal muscle and cardiovascular systems. Regular exercise provides significant health benefits like reduced mortality, improved glycemic control, and reduced risks of various diseases. Exercise is an important component of weight loss and maintenance by increasing calorie burn and lean muscle mass. The guidelines recommend accumulating 30-60 minutes per day of moderate exercise most days of the week.
Osteoarthritis
Here are the key points when osteoarthritis patients may need to see an orthopedic surgeon:
- If drug therapy (e.g. analgesics, NSAIDs, viscosupplementation) is ineffective at providing adequate pain relief and improving function over time. Surgery can provide pain relief when conservative measures have failed.
- If function is severely impaired due to advanced osteoarthritis. Total joint replacement surgery may be indicated to improve quality of life.
- If osteoarthritis is causing deformities of the joint (e.g. knees turned inward). Surgical correction may be needed in addition to joint replacement.
- For intra-articular corticosteroid injections if conservative measures and viscosupplementation have failed.
Similar to Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model (20)
ortho 04 drugs in orthopaedic (principle & common use)
ortho 04 drugs in orthopaedic (principle & common use)
L'idrossitirosolo è in grado di proteggere e aumentare l'attività dei mitocon...
L'idrossitirosolo è in grado di proteggere e aumentare l'attività dei mitocon...
Lion's Mane Mushroom: Benefits for Athletes and Active Individuals
Lion's Mane Mushroom: Benefits for Athletes and Active Individuals
Short inter-set rest blunts resistance exercise-induced
Short inter-set rest blunts resistance exercise-induced
More from Emilio Solomon
Southeast Asian Studies- Final Exam
This (final exam) is part of the requirement for Southeast Asian Studies, a course I took at Mahidol University International College. There are five different responses, which all discuss social issues related to Southeast Asia.
Disc herniation
A presentation about disc herniation (L4- L5) made in ICBI 341 Neurobiology, a class I took at Mahidol University International College.
Therapeutic uses of enzymes
This is a presentation I created for my ICBI 436 Industrial Enzymology, a Biotechnology course I took at Mahidol University International College (MUIC)
Corporate marketing internship assignment redo
The document discusses ways to drive more traffic to the ecommerceiq website. It first analyzes the website's content and target audience of ecommerce professionals. It then proposes three ways to generate more traffic: 1) Creating a Facebook page to share articles and reports, 2) Promoting the site on business websites like Business Insider through ads, and 3) Hosting events for ecommerce professionals to present insights and distribute marketing materials. The goal is to expand ecommerceiq's reach within Southeast Asia's ecommerce industry.
Vitamin B3 deficiency
This is a presentation I presented during my pathobiology course in college. The presentation discusses vitamin B3 deficiency. in terms of background, nutrition, pathogenesis, and signs & symptoms.
Serum Ischemia-Modified Albumin in Preterm Babies with Respiratory Distress S...
This is a presentation from my seminar in biological sciences course. The presentations discusses serum ischemia-modified albumin in preterm babies with respiratory distress syndrome.
Evaluation of the lacZ gene in Escherichia coli mutagenesis using pBluescript...
This was a research paper I wrote for my Integrated Laboratory Techniques in Biological Sciences II course.
Evaluation of the lacZ gene in Escherichia coli mutagenesis using pBluescript and pTn5: Km vectors
“Immobilization of urease using glycidyl methacrylate grafted nylon-6-membranes”
This was a paper I did for Industrial Enzymology; a Biotechnology elective course in my college.
“Immobilization of urease using glycidyl methacrylate grafted nylon-6-membranes”
Evaluation of antioxidant properties in different colors of asian rice (oryza...
Senior project for my major (Biological Sciences: Biomedical Science concentration)
Evaluation of antioxidant properties in different colors of asian rice (oryza sativa) against insecticide carbosulfan using mealworm (Tenebrio molitor) assay
Human Anatomy
This is a pdf file showing how I study for college Human Anatomy (Introduction). I used a surface pro 3 for these notes. Any aspiring doctors and nurses can take a look at this document
Philosophy assignment redo
This is an essay I wrote during my sophomore year of college. It's for my Introduction to Philosophy class. It's a redo assignment, which discusses Hume's and Descartes' skeptical views.
Senior Project- BSc Biological Sciences
This is my senior thesis. My project focuses on the evaluation of antioxidant properties of different colors of asian rice against carbosulfan insecticide using mealworms.
More from Emilio Solomon (12)
Serum Ischemia-Modified Albumin in Preterm Babies with Respiratory Distress S...
Serum Ischemia-Modified Albumin in Preterm Babies with Respiratory Distress S...
Evaluation of the lacZ gene in Escherichia coli mutagenesis using pBluescript...
Evaluation of the lacZ gene in Escherichia coli mutagenesis using pBluescript...
“Immobilization of urease using glycidyl methacrylate grafted nylon-6-membranes”
“Immobilization of urease using glycidyl methacrylate grafted nylon-6-membranes”
Evaluation of antioxidant properties in different colors of asian rice (oryza...
Evaluation of antioxidant properties in different colors of asian rice (oryza...
Recently uploaded
Top-Vitamin-Supplement-Brands-in-India List
Swisschem Dermacare provides the Top 10 Vitamin Supplement Brands in India. To know more about us give us call at our official number
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Top 10 Best Ayurvedic Kidney Stone Syrups in India
we have mentioned the best 10 ayurvedic Kidney Stone Syrups. You can check all these products and choose the best one for yourself.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
ABDOMINAL TRAUMA in pediatrics part one.
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
share - Lions, tigers, AI and health misinformation, oh my!.pptx
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...chandankumarsmartiso
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel With 100% Satisfaction
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...chandankumarsmartiso
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun Women Seeking Service
The Electrocardiogram - Physiologic Principles
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Recently uploaded (20)
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Top 10 Best Ayurvedic Kidney Stone Syrups in India
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
share - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Phone Us ❤8107221448❤ #ℂall #gIRLS In Dehradun By Dehradun @ℂall @Girls Hotel...
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
#cALL# #gIRLS# In Dehradun ꧁❤8107221448❤꧂#cALL# #gIRLS# Service In Dehradun W...
Thyroid Gland- Gross Anatomy by Dr. Rabia Inam Gandapore.pptx
Thyroid Gland- Gross Anatomy by Dr. Rabia Inam Gandapore.pptx
Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model
- 1. Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model Dur-Zong Hsu, Pei-Yi Chu, I-Ming Jou Department of Orthopedics, National Cheng Kung University Hospital, Tainan, Taiwan 5580132
- 2. Sesame oil Oil extracted from sesame seeds Primarily for eating, but can also be used for cosmetics Has antioxidant, anti-cancer, anti-inflammatory properties Helps in lowering blood sugar and maintaining skin integrity
- 4. Osteoarthritis Also called degenerative joint disease or “wear and tear” arthritis Most common form of arthritis 15% of the population suffer from osteoarthritis The risk of developing osteoarthritis is 40% in men and 47% in women
- 6. Reactive oxygen species (ROS) Chemically reactive molecules that contain O2 Generated during oxidative phosphorylation and cellular responses to xenobiotics, cytokines, and bacterial invasion Disrupts cell signaling, proliferation, and survival
- 8. House rats Osteoarthritis induction Experiment I Experiment II Osteoarthritis (n=5) Sham (n=5) Osteoarthritis (n=5) Sham (n=5) Sesame oil (n=5)
- 9. Osteoarthritis induction Rats were induced with medial meniscal transection (MNX) surgery Rats were given inhalational anesthetics during surgery Rats were given cephalexin 1 h before surgery and 12, 24, 36 h after surgery
- 10. Experiments I: Levels of osteoarthritis pain were assessed in both experimental and control groups 0, 1, 4, 7, and 14 days following Sham or MNX operation II: Rat quadriceps muscles were collected 7 days after Sham or MNX operation. Muscular LPO, GSH, superoxide anion, peroxynitrite and GPx expression as well as nuclear Nrf2 expression levels were assessed
- 11. Outcomes Joint pain (Weight distribution) Lipid peroxidation (Superoxide anion, nitric oxide, peroxynitrite) Antioxidant activity (GPx, GSH) Transcription/ translation of antioxidant enzymes (Nrf2)
- 12. Results
- 13. Fig. 1. Time-course study of MNX-induced OA-like joint pain in rats.
- 14. Fig. 2. Effect of sesame oil on MNX-induced OA-like joint pain in rats.
- 15. Fig. 3. Effects of sesame oil on serum and muscular LPO levels in OA rats.
- 16. Fig. 4. Effects of sesame oil on muscular ROS generation in OA rats.
- 17. Fig. 5. Effects of sesame oil on muscular GSH and GPx levels in OA rats.
- 18. Fig. 6. Effects of sesame oil on muscular Nrf2 level in OA rats.
- 19. Outcomes Result Weight distribution Increased Antioxidant activity Increased Transcription/translation of antioxidant enzymes Increased Lipid peroxidation Decreased Summary
- 20. Discussion Muscle dysfunction plays a crucial role in the pathogenesis of osteoarthritis and joint pain Physical therapy has been shown in preventing the development of osteoarthritis Increased oxidative stress in skeletal muscle can induce muscle atrophy
- 22. References Hsu, D.-Z., Chu, P.-Y., & Jou, I. M. Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in osteoarthritis rat model. Journal of Nutritional Biochemistry, 29, 36- 40. doi: 10.1016/j.jnutbio.2015.10.007