A central venous access device (CVAD) is a catheter inserted into the central venous system to deliver fluids, medications, blood products, and nutrition either short-term or long-term. CVADs are commonly used when peripheral access is limited or for ongoing home therapy. There are several types of CVADs including tunneled catheters, nontunneled catheters, PICCs, and implanted ports. Proper care and maintenance of CVADs includes regular dressing changes using aseptic technique, flushing the catheter with saline to maintain patency, and locking catheters with saline or low-dose heparin between uses.