Guido Jansen discusses creating an optimization culture at companies. He notes that optimization efforts cannot be done centralized and need buy-in across distributed teams to connect insights. Building trust around data and experimentation is important. While some clients lack an experimental DNA and see online as just lead-gen, others have scale, data science teams, and management buy-in that can enable success. Jansen advocates moving from terms like CRO and A/B testing to focus on idea validation, business growth, and innovation. Onboarding people outside digital teams is also important for the culture.