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Complication
s of Sinusitis
Three main categories
• Orbital (60-75%)
• Intracranial (15-20%)
• Bony (5-10%)
Radiography
–Computed tomography (CT) best
for orbit
–Magnetic resonance imaging (MRI)
best for intracranium
Orbital
• Most commonly involved
complication site
• Proximity to ethmoid
sinuses
• Periorbita/orbital septum
is the only soft-tissue
barrier
• Direct extension through lamina
papyracea
• Impaired venous drainage from
thrombophlebitis
• Progression within 2 days
• Children more susceptible
–< 7 years – isolated orbital
(subperiosteal abscess)
–> 7 years – orbital and
intracranial complications
Orbital
Complications
Chandler Criteria
• Preseptal cellulitis
• Orbital cellulitis
• Subperiosteal abscess
• Orbital abscess
• Cavernous sinus
thrombosis
Preseptal
cellulitis
Symptomatology
• Eyelid edema and
erythema
• Extraocular
movement intact
• Normal vision
• May have eyelid
abscess
CT reveals diffuse
thickening of lid and
conjunctiva
Treatment
• Medical therapy typically
sufficient
–Intravenous antibiotics
–Head of bed elevation
–Warm compresses
• Facilitate sinus drainage
–Nasal decongestants
–Mucolytics
–Saline irrigation
Orbital
cellulitis
Symptomatology
• Post-septal infection
• Eyelid edema and
erythema
• Proptosis and
chemosis
• Limited or no
extraocular
movement limitation
• No visual impairment
• No discrete abscess
Low-attenuation
adjacent to lamina
papyracea on CT
Facilitate sinus drainage
• Nasal decongestants
• Mucolytics
• Saline irrigations
Medical therapy typically sufficient
• Intravenous antibiotics
• Head of bed elevation
• Warm compresses
May need surgical drainage
• Visual acuity 20/60 or worse
• No improvement or progression within
48 hours
Feature Preseptal Cellulitis Orbital Cellulitis
Proptosis Absent Present
Motility Normal Decreased
Pain on motion Absent Present
Orbital pain Absent Present
Vision Normal May be decreased
Pupillary reaction Normal May be abnormal; ±
afferent pupillary
defect
Chemosis Rare Common
Corneal sensation Normal May be reduced
Ophthalmoscopy Normal May be abnormal; ±
venous congestion; ±
disc edema
Systemic signs
(e.g., fever, malaise)
Mild Commonly severe
Subperiosteal Abscess
• Pus formation between
periorbita and lamina papyracea
Displace orbital contents
downward and laterally
• Proptosis, chemosis,
ophthalmoplegia
• Risk for residual visual sequelae
• May rupture through septum
and present in eyelids
Surgical drainage
• Worsening visual acuity or
extraocular movement
• Lack of improvement after 48
hours
May be treated medically in 50-
67%
• Meta-analysis cure rate 26-
93%
• Combined treatment 95-100%
• Open ethmoids and remove lamina
papyracea
Approaches
• External ethmoidectomy (Lynch
• incision)is most preferred
• Endoscopic ideal for medial
abscesses
• Transcaruncular approach
• Transconjunctival incision
• Extend medially around lacrimal
caruncle
Orbital Abscess
• Pus formation within orbital
tissues
• Severe exophthalmos and
chemosis
• Ophthalmoplegia
• Visual impairment
• Risk for irreversible blindness
• Can spontaneously drain through
•Incise periorbita and
drain intraconal
abscess
•Similar approaches as
with subperiosteal
abscess
•Lynch incision
•Endoscopic
Cavernous Sinus Thrombosis
Symptomatology
• Orbital pain
• Proptosis and chemosis
• Ophthalmoplegia
• Symptoms in contralateral eye
• Associated with sepsis and meningismus
Radiology
• Poor venous enhancement on CT
• Better visualized on MRI
INTRACRANIAL
COMPLICATION
S
• Occurs more commonly in
CRS
• Mucosal scarring, polypoid
changes
• Hidden infectious foci with
poor antibiotic penetration
• Male teenagers affected
more than children
Direct extension
Sinus wall erosion
Traumatic fracture lines
Neurovascular foramina
(optic and olfactory
nerves)
Hematogenous spread
Diploic skull veins
Ethmoid bone
•Meningitis
•Epidural abscess
•Subdural abscess
•Intracerebral abscess
•Cavernous sinus,
venous sinus
• Fever (92%)
• Headache (85%)
• Nausea, vomiting (62%)
• Altered consciousness (31%)
• Seizure (31%)
• Hemiparesis (23%)
• Visual disturbance (23%)
• Meningismus (23%)
Meningitis
• Headache,meningismus
• Fever, septic
• Cranial nerve palsies
• Sinusitis is unusual cause of
meningitis, Sphenoiditis, Ethmoiditis
• Usually amenable with medical
treatment
• Drain sinuses if no improvement
after 48 hours
• Hearing loss and seizure sequelae
Epidural Abscess
• Second-most common intracranial
complication
• Generally a complication of frontal
sinusitis
• Symptomatology
– Fever (>50%)
– Headache (50-73%)
– Nausea, vomiting
– Papilledema
– Hemiparesis
– Seizure (4-63%)
• Lumbar puncture contraindicated
• Prophylactic seizure therapy not
necessary
Antibiotics
• Good intracerebral penetration
• Typically for 4-8 weeks
Drain sinuses and abscess
• Frontal sinus trephination
• Frontal sinus cranialization
• Uncommon, frontal and
frontoparietal lobes
• Generally from frontal
sinusitis
• Sphenoid
• Ethmoids
• Mortality 20-30%
• Neurologic sequelae 60%
Subdural Abscess
• Generally from frontal or
ethmoid sinusitis
• Third-most common intracranial
complication, rapid deterioration
• Mortality in 25-35%
• Residual neurologic sequelae in
35-55%
• Accompanies 10% of epidural
abscesses
Symptomatology
•Headaches
•Fever
•Nausea, vomiting
•Hemiparesis
•Lethargy, coma
• Lumbar puncture potentially fatal
Aggressive medical therapy
• Antibiotics
• Anticonvulsants
• Hyperventilation, mannitol
• Steroids
Drain sinuses and abscess
• Medical therapy possible if < 1.5cm
• Craniotomy or stereotactic burr hole
• Endoscopic or external sinus drainage
Intracerebral Abscess
• Uncommon, frontal & frontoparietal
lobes
• Generally from frontal sinusitis,
Sphenoid, Ethmoids
• Mortality 20-30%,Neurologic
sequelae 60%
• Nausea, vomiting (40%)
• Seizure (25-35%), Meningismus ,
Papilledema (25%)
Symptomatology
• Headache (70%)
•Mental status change
(65%)
• Focal neurological
deficit (65%)
• Fever (50%)
Bony: Pott’s puffy tumor
• Frontal sinusitis with acute
osteomyelitis
• Subperiosteal pus collection leads to
“puffy” fluctuance
• Rare complication
• Only 20-25 cases reported in post-
antibiotic era Less than 50 pediatric
cases in past 10 years
Symptomatology
• Headache
• Fever
• Neurologic findings
• Periorbital or frontal
swelling
• Nasal congestion,
rhinorrhea
Conclusions
• Complications are less common with
antibiotics
– Orbital
– Intracranial
– Bony
– Can result in drastic sequelae
• Drain abscess and open involved sinuses
– Surgical involvement
– Ophthalmology
– Neurosurgery

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Complications of Sinusitis (1).pptx

  • 2. Three main categories • Orbital (60-75%) • Intracranial (15-20%) • Bony (5-10%) Radiography –Computed tomography (CT) best for orbit –Magnetic resonance imaging (MRI) best for intracranium
  • 3. Orbital • Most commonly involved complication site • Proximity to ethmoid sinuses • Periorbita/orbital septum is the only soft-tissue barrier
  • 4. • Direct extension through lamina papyracea • Impaired venous drainage from thrombophlebitis • Progression within 2 days • Children more susceptible –< 7 years – isolated orbital (subperiosteal abscess) –> 7 years – orbital and intracranial complications
  • 5. Orbital Complications Chandler Criteria • Preseptal cellulitis • Orbital cellulitis • Subperiosteal abscess • Orbital abscess • Cavernous sinus thrombosis
  • 6.
  • 7. Preseptal cellulitis Symptomatology • Eyelid edema and erythema • Extraocular movement intact • Normal vision • May have eyelid abscess CT reveals diffuse thickening of lid and conjunctiva
  • 8. Treatment • Medical therapy typically sufficient –Intravenous antibiotics –Head of bed elevation –Warm compresses • Facilitate sinus drainage –Nasal decongestants –Mucolytics –Saline irrigation
  • 9. Orbital cellulitis Symptomatology • Post-septal infection • Eyelid edema and erythema • Proptosis and chemosis • Limited or no extraocular movement limitation • No visual impairment • No discrete abscess Low-attenuation adjacent to lamina papyracea on CT
  • 10.
  • 11. Facilitate sinus drainage • Nasal decongestants • Mucolytics • Saline irrigations Medical therapy typically sufficient • Intravenous antibiotics • Head of bed elevation • Warm compresses May need surgical drainage • Visual acuity 20/60 or worse • No improvement or progression within 48 hours
  • 12. Feature Preseptal Cellulitis Orbital Cellulitis Proptosis Absent Present Motility Normal Decreased Pain on motion Absent Present Orbital pain Absent Present Vision Normal May be decreased Pupillary reaction Normal May be abnormal; ± afferent pupillary defect Chemosis Rare Common Corneal sensation Normal May be reduced Ophthalmoscopy Normal May be abnormal; ± venous congestion; ± disc edema Systemic signs (e.g., fever, malaise) Mild Commonly severe
  • 13. Subperiosteal Abscess • Pus formation between periorbita and lamina papyracea Displace orbital contents downward and laterally • Proptosis, chemosis, ophthalmoplegia • Risk for residual visual sequelae • May rupture through septum and present in eyelids
  • 14.
  • 15.
  • 16. Surgical drainage • Worsening visual acuity or extraocular movement • Lack of improvement after 48 hours May be treated medically in 50- 67% • Meta-analysis cure rate 26- 93% • Combined treatment 95-100%
  • 17. • Open ethmoids and remove lamina papyracea Approaches • External ethmoidectomy (Lynch • incision)is most preferred • Endoscopic ideal for medial abscesses • Transcaruncular approach • Transconjunctival incision • Extend medially around lacrimal caruncle
  • 18. Orbital Abscess • Pus formation within orbital tissues • Severe exophthalmos and chemosis • Ophthalmoplegia • Visual impairment • Risk for irreversible blindness • Can spontaneously drain through
  • 19.
  • 20.
  • 21. •Incise periorbita and drain intraconal abscess •Similar approaches as with subperiosteal abscess •Lynch incision •Endoscopic
  • 22. Cavernous Sinus Thrombosis Symptomatology • Orbital pain • Proptosis and chemosis • Ophthalmoplegia • Symptoms in contralateral eye • Associated with sepsis and meningismus Radiology • Poor venous enhancement on CT • Better visualized on MRI
  • 23.
  • 24.
  • 26. • Occurs more commonly in CRS • Mucosal scarring, polypoid changes • Hidden infectious foci with poor antibiotic penetration • Male teenagers affected more than children
  • 27. Direct extension Sinus wall erosion Traumatic fracture lines Neurovascular foramina (optic and olfactory nerves) Hematogenous spread Diploic skull veins Ethmoid bone
  • 29. • Fever (92%) • Headache (85%) • Nausea, vomiting (62%) • Altered consciousness (31%) • Seizure (31%) • Hemiparesis (23%) • Visual disturbance (23%) • Meningismus (23%)
  • 30. Meningitis • Headache,meningismus • Fever, septic • Cranial nerve palsies • Sinusitis is unusual cause of meningitis, Sphenoiditis, Ethmoiditis • Usually amenable with medical treatment • Drain sinuses if no improvement after 48 hours • Hearing loss and seizure sequelae
  • 31. Epidural Abscess • Second-most common intracranial complication • Generally a complication of frontal sinusitis • Symptomatology – Fever (>50%) – Headache (50-73%) – Nausea, vomiting – Papilledema – Hemiparesis – Seizure (4-63%)
  • 32. • Lumbar puncture contraindicated • Prophylactic seizure therapy not necessary Antibiotics • Good intracerebral penetration • Typically for 4-8 weeks Drain sinuses and abscess • Frontal sinus trephination • Frontal sinus cranialization
  • 33. • Uncommon, frontal and frontoparietal lobes • Generally from frontal sinusitis • Sphenoid • Ethmoids • Mortality 20-30% • Neurologic sequelae 60%
  • 34. Subdural Abscess • Generally from frontal or ethmoid sinusitis • Third-most common intracranial complication, rapid deterioration • Mortality in 25-35% • Residual neurologic sequelae in 35-55% • Accompanies 10% of epidural abscesses
  • 36. • Lumbar puncture potentially fatal Aggressive medical therapy • Antibiotics • Anticonvulsants • Hyperventilation, mannitol • Steroids Drain sinuses and abscess • Medical therapy possible if < 1.5cm • Craniotomy or stereotactic burr hole • Endoscopic or external sinus drainage
  • 37. Intracerebral Abscess • Uncommon, frontal & frontoparietal lobes • Generally from frontal sinusitis, Sphenoid, Ethmoids • Mortality 20-30%,Neurologic sequelae 60% • Nausea, vomiting (40%) • Seizure (25-35%), Meningismus , Papilledema (25%)
  • 38. Symptomatology • Headache (70%) •Mental status change (65%) • Focal neurological deficit (65%) • Fever (50%)
  • 39. Bony: Pott’s puffy tumor • Frontal sinusitis with acute osteomyelitis • Subperiosteal pus collection leads to “puffy” fluctuance • Rare complication • Only 20-25 cases reported in post- antibiotic era Less than 50 pediatric cases in past 10 years
  • 40.
  • 41. Symptomatology • Headache • Fever • Neurologic findings • Periorbital or frontal swelling • Nasal congestion, rhinorrhea
  • 42. Conclusions • Complications are less common with antibiotics – Orbital – Intracranial – Bony – Can result in drastic sequelae • Drain abscess and open involved sinuses – Surgical involvement – Ophthalmology – Neurosurgery