This document provides guidance on effectively communicating about genetic engineering and GMOs to the general public. It begins by explaining that most people lack understanding of the science and are influenced by manufactured risk. It recommends starting discussions by establishing common ground and values, then using logic and evidence while also appealing to emotion. Key points to convey include: genetic improvement is a continuum that predates GMOs; GMOs extend precise breeding; few commercially available GMOs focus on virus/insect resistance and herbicide tolerance; strengths and limitations should be acknowledged. Lost opportunities from GMO opposition like golden rice are highlighted. Farmers are suggested as credible communicators. Overall it emphasizes understanding audiences, focusing on the unsure middle, and discussing benefits of applications like disease