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Common Problems in the Elderly
• Urinary Incontinence
• Adverse Drug Reactions
• Dizziness
• Falls
• Delirium
…???
Urinary Incontinence
• Defined as the involuntary loss of urine
• Seen in all age groups, but more prevalent in
those over 65 years
• Causes social and hygiene problems
• Can lead to skin damage if severe
Urinary Incontinence
Contributory Factors
• UTI
• Severe Constipation
• Drugs (eg. Diuretics)
• Hypergylcemia
• Hyercalcemia
• Restricted mobility
• Acute confusion
Urinary Incontinence
Investigations
• Maintain a diary to ascertain patter of urinary
loss
• USG: Measure residual urine
• Assess for vaginal prolapse and atrophic
vaginitis (women)
• Per rectal exam: assess prostate (men)
Urinary Incontinence
Management
Urge incontinence: due to detrusor overactivity
(urgency and frequency)
•Bladder retraining
•Antimuscarinic drugs, e.g. solifenacin, tolterodine
Stress incontinence: weakness of the pelvic floor muscles allows leakage of urine
when intra-abdominal pressure rises
•Pelvic floor muscle retraining
•Surgical interventions
Overflow incontinence: obstruction to bladder outflow
(Residual volume > 100mL)
•Surgical relief (e.g. prostatectomy)
•Intermittent catherization
Other (e.g. severe stroke, dementia)
•Timed toileting
Adverse Drug Reactions
• Can result in symptoms, abnormal physical
signs, and altered laboratory tests
• Account for 20% of admissions in those aged
over 65 years
• Partly because the elderly receive more
prescribed drugs than younger people
Adverse Drug Reactions
Risk Factors
• Polypharmacy
• Age-related changes in pharmacodynamic and
pharmacokinetic factors
• Impaired homeostatic mechanisms like
baroreceptor responses, plasma volume and
electrolyte control
• Non-adherence
Adverse Drug Reactions
Polypharmacy
• Defined as the use of four or more drugs
• Factors leading to polypharmacy:
– Multiple pathology
– Poor patient education
– Lack of routine review of medications
– Patients expectations of prescribing
– Over use of drug interventions by doctors
– Attendance at multiple specialist clinics
– Poor communication between specialists
Common ADRs in the elderly
Drug Class Adverse Reaction
NSAIDs GI Bleeding
Peptic ulceration
Renal Impairment
Diuretics
ACE Inhibitors
Renal impairment
Hypotension/Postural Hypotension
Electrolyte imbalance
Warfarin Bleeding
β-Blockers Hypotension/Postural Hypotension
Bradycardia or Heart block
Opiates Constipation or urinary retention
Vomiting
Delirium
Antidepressants Delirium
Hypotension/Postural Hypotension
Falls
Benzodiazepines Delirium
Falls
Anticholinergics Constipation or urinary retention
Adverse Drug Reactions
Management
• ADRs should be considered in any presenting
complaint
• Minimize amount and dosage of drugs
• Ensure patient understands and adheres to
dosage regime
• Review medication regularly
• Discontinue drugs that are no longer needed
or contraindicated
Dizziness
• Occurs in 30% of those over 65 years
• Multifactorial
• Also described as lightheadedness, vertigo, or
unsteadiness
Dizziness
Acute Onset
• Hypotension due to arrhythmia, MI, GI bleed
or pulmonary embolism
• Onset of posterior fossa stroke
• Vestibular neuronitis
Dizziness
Lightheadedness
• Suggestive of reduced cerebral perfusion
• Due to
– Structural cardiac disease (Left ventricular
dysfunction or aortic stenosis)
– Arrhythmia
– Vasovagal syndrome
– Postural hypotension
– Anti-hypertensive medications
Dizziness
Vertigo
• Suggestive of labyrinthine or brainstem
disease
• Commonly due to benign positional vertigo
• If other brain stem signs present, do an MRI to
exclude a cerebello-pontine angle lesion
Dizziness
Unsteadiness
• Suggestive of joint or neurological disease
• Examine gait, joints and do a CNS examination
• Usually improved with physiotherapy
• If patient has history of falls, do specific
interventions
– Exercise training
– Correct medication
– Correct visual impairments
– Home environmental hazard assessment
– Safety education

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Common problems in the elderly

  • 1. Common Problems in the Elderly • Urinary Incontinence • Adverse Drug Reactions • Dizziness • Falls • Delirium …???
  • 2. Urinary Incontinence • Defined as the involuntary loss of urine • Seen in all age groups, but more prevalent in those over 65 years • Causes social and hygiene problems • Can lead to skin damage if severe
  • 3. Urinary Incontinence Contributory Factors • UTI • Severe Constipation • Drugs (eg. Diuretics) • Hypergylcemia • Hyercalcemia • Restricted mobility • Acute confusion
  • 4. Urinary Incontinence Investigations • Maintain a diary to ascertain patter of urinary loss • USG: Measure residual urine • Assess for vaginal prolapse and atrophic vaginitis (women) • Per rectal exam: assess prostate (men)
  • 5. Urinary Incontinence Management Urge incontinence: due to detrusor overactivity (urgency and frequency) •Bladder retraining •Antimuscarinic drugs, e.g. solifenacin, tolterodine Stress incontinence: weakness of the pelvic floor muscles allows leakage of urine when intra-abdominal pressure rises •Pelvic floor muscle retraining •Surgical interventions Overflow incontinence: obstruction to bladder outflow (Residual volume > 100mL) •Surgical relief (e.g. prostatectomy) •Intermittent catherization Other (e.g. severe stroke, dementia) •Timed toileting
  • 6. Adverse Drug Reactions • Can result in symptoms, abnormal physical signs, and altered laboratory tests • Account for 20% of admissions in those aged over 65 years • Partly because the elderly receive more prescribed drugs than younger people
  • 7. Adverse Drug Reactions Risk Factors • Polypharmacy • Age-related changes in pharmacodynamic and pharmacokinetic factors • Impaired homeostatic mechanisms like baroreceptor responses, plasma volume and electrolyte control • Non-adherence
  • 8. Adverse Drug Reactions Polypharmacy • Defined as the use of four or more drugs • Factors leading to polypharmacy: – Multiple pathology – Poor patient education – Lack of routine review of medications – Patients expectations of prescribing – Over use of drug interventions by doctors – Attendance at multiple specialist clinics – Poor communication between specialists
  • 9. Common ADRs in the elderly Drug Class Adverse Reaction NSAIDs GI Bleeding Peptic ulceration Renal Impairment Diuretics ACE Inhibitors Renal impairment Hypotension/Postural Hypotension Electrolyte imbalance Warfarin Bleeding β-Blockers Hypotension/Postural Hypotension Bradycardia or Heart block Opiates Constipation or urinary retention Vomiting Delirium Antidepressants Delirium Hypotension/Postural Hypotension Falls Benzodiazepines Delirium Falls Anticholinergics Constipation or urinary retention
  • 10. Adverse Drug Reactions Management • ADRs should be considered in any presenting complaint • Minimize amount and dosage of drugs • Ensure patient understands and adheres to dosage regime • Review medication regularly • Discontinue drugs that are no longer needed or contraindicated
  • 11. Dizziness • Occurs in 30% of those over 65 years • Multifactorial • Also described as lightheadedness, vertigo, or unsteadiness
  • 12. Dizziness Acute Onset • Hypotension due to arrhythmia, MI, GI bleed or pulmonary embolism • Onset of posterior fossa stroke • Vestibular neuronitis
  • 13. Dizziness Lightheadedness • Suggestive of reduced cerebral perfusion • Due to – Structural cardiac disease (Left ventricular dysfunction or aortic stenosis) – Arrhythmia – Vasovagal syndrome – Postural hypotension – Anti-hypertensive medications
  • 14. Dizziness Vertigo • Suggestive of labyrinthine or brainstem disease • Commonly due to benign positional vertigo • If other brain stem signs present, do an MRI to exclude a cerebello-pontine angle lesion
  • 15. Dizziness Unsteadiness • Suggestive of joint or neurological disease • Examine gait, joints and do a CNS examination • Usually improved with physiotherapy • If patient has history of falls, do specific interventions – Exercise training – Correct medication – Correct visual impairments – Home environmental hazard assessment – Safety education