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Medical Management of
urinary incontinence in old age
Anoja Rajapakse
Consultant Geriatrician
30th November 2019
Kings Mill Hospital
Sherwood Forest NHS Foundation Trust
United Kingdom
Urinary incontinence
 Continence is one of the Geriatric Giants
 A complaint of any involuntary leakage of urine
International Continence Society (ICS)
 Abnormality of function of the lower urinary tract or
systemic illness.
 Affect all ages, both genders, varying severity
Types of urinary incontinence
 Stress Incontinence
 Urge Incontinence or Over Active Bladder (OAB)
 Mixed Incontinence
 Other types – Bladder outlet obstruction, Functional
Prevalence by age groups
Assessment
 Always ask about urinary incontinence
 If yes, ask more details
◦ Frequency, urgency, hesitancy
◦ Precipitating factors
◦ Medication
◦ Comorbidity/previous surgery
◦ Details of childbirth
◦ Mobility
 What containment products?
Treatable causes -DIAPPERS
 Delirium/Depression
 Infection
 Atrophy of vulva
 Pharmacological - medication
 Pelvic pathology and Pregnancy
 Excess urine production
 Reduced mobility
 Stool impaction
Examination
 General, abdominal and neurological examination.
 Pelvic examination in women
- muscle strength
- uterine prolapse
- Bladder stress test
 Rectal examination
 prostate size
Investigations
 Basic blood investigations
 Prostate specific antigen
 Urine analysis
 Blood or protein look for renal tract pathology
 Glucose look for diabetes Mellitus
 Nitrates +/- leucocytes look for infection
 Bladder/Void diary
 Post-void bladder scan
Voiding diary for 3 days
Record to understand bladder function
 Day + night frequency
 Precipitating symptoms - coughing, laughing
 Was there leaking of urine?
 Urine volume lost involuntarily
 Warning of full bladder and for how long?
 How many pads were used during day and during
night?
 Were the pads damped or soaked in urine
3-day Bladder Chart
Time Drink
type
Drink
volume
Volume
of urine
Leak
Y/N?
Bladder Chart
 What is taken by person
◦ Caffeine containing drinks
◦ Carbonated drinks
◦ Medication
 How much is taken by person
 Too little fluids and too much fluids both can
cause bladder problems
Assessment of residual urine
 Post-void bladder scan
 With ageing post-void residual urine volume
increases
 In-out Catheterization
 Higher incidence of urinary tract infection
Red flags
 Persisting bladder or urethral pain
 Pelvic masses
 Associated faecal incontinence
 Suspected neurological disease
 Symptoms of voiding difficulty
 Suspected urogenital fistulae
 Previous pelvic surgery
 Previous pelvic irradiation
Urodynamic testing
 After lifestyle changes
 Helps confirm detrusor instability
 Voiding dysfunction due to uterine prolapse or
benign prostatic enlargement
 Previous surgery – BPH, stress incontinence
Urodynamic testing
Stress incontinence
 Commoner in younger women, post-TURP
 Small volumes of urine leaked
 Precipitating factors – coughing, sneezing, bending
 Symptoms mainly during daytime
Lifestyle change
 Weight reduction
 Drink enough fluids
 Avoid bladder irritants
 Medication antipsychotics, alpha agonist
 Caffeine  decaffeinated
 Carbonated drinks
 Alcohol
Treatment for stress
incontinence
 Pelvic floor exercises at least for 3 months (level -1
evidence)
 Electrical stimulation and biofeedback for women
who cannot actively contract pelvic floor muscles
 Duloxetine has evidence to improve symptoms
 Transurethral bulking agents, Perineal sling,
artificial urinary sphincter
Urgency incontinence
 Symptoms of urgency, hesitancy, poor stream
 Daytime and night time frequency is similar
 Larger volumes of urine is leaked
 BPH, neurological conditions, medication
Urgency incontinence
 Bladder re-training for 6 months (level -1 evidence)
 Antimuscarinic drugs
 ß3 agonist - mirobegron
 Transdermal oxybutinine is available
 Need to take for about 4 weeks to see benefit
 Botox therapy to the bladder
Antimuscarinics
 Oxybutynin
 Solifenacin
 Tolterodine
 Side effects – confusion, dry mouth, urine retention
Neurostimulation
 Transcutaneous sacral nerve stimulation,
transcutaneous posterior tibial nerve stimulation in
OAB – no evidence
 Percutaneous sacral nerve stimulation and
percutaneous posterior tibial nerve stimulation -
some success
Percutaneous sacral nerve
stimulation
 Cause pain,
bleeding, infection
 Need repeated
therapy
Botox therapy
Urinary catheters
 Indications:
◦ Retention
◦ Skin wounds, pressure ulcers contaminated by urine
◦ Distress or disruption caused by bed and clothing changes
 Intermittent urinary catheter
 Indwelling urethral catheter
 Indwelling suprapubic catheter
Mixed incontinence
 Treat pelvic floor exercise when stress
incontinence symptoms are predominant problem
 Bladder re-training when OAB symptoms are
predominant
 Treat the predominant symptom with medication
when above has failed
Nocturnal enuresis
 More than 1/3 the total urine passed at night
 Look for fluid overload - congestive cardiac failure
 Limiting oral fluid intake after 1800 hours
 Medication
◦ Diuretics around midday
◦ Desmopressin - sodium monitoring
Oestrogen
 Transvaginal oestrogen is beneficial to control OAB
symptoms with vulvar atrophy.
 Reduce recurrent urinary tract infection
 Do not use systemic oestrogen
 NICE has guidelines for management of urinary
continence in women (CG 171) – November, 2015
 NICE Guideline (NG123) April 2019
Thank you
a.rajapakse@nhs.net

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Urinary incontinence

  • 1. Medical Management of urinary incontinence in old age Anoja Rajapakse Consultant Geriatrician 30th November 2019
  • 2. Kings Mill Hospital Sherwood Forest NHS Foundation Trust United Kingdom
  • 3. Urinary incontinence  Continence is one of the Geriatric Giants  A complaint of any involuntary leakage of urine International Continence Society (ICS)  Abnormality of function of the lower urinary tract or systemic illness.  Affect all ages, both genders, varying severity
  • 4. Types of urinary incontinence  Stress Incontinence  Urge Incontinence or Over Active Bladder (OAB)  Mixed Incontinence  Other types – Bladder outlet obstruction, Functional
  • 6. Assessment  Always ask about urinary incontinence  If yes, ask more details ◦ Frequency, urgency, hesitancy ◦ Precipitating factors ◦ Medication ◦ Comorbidity/previous surgery ◦ Details of childbirth ◦ Mobility  What containment products?
  • 7. Treatable causes -DIAPPERS  Delirium/Depression  Infection  Atrophy of vulva  Pharmacological - medication  Pelvic pathology and Pregnancy  Excess urine production  Reduced mobility  Stool impaction
  • 8. Examination  General, abdominal and neurological examination.  Pelvic examination in women - muscle strength - uterine prolapse - Bladder stress test  Rectal examination  prostate size
  • 9.
  • 10. Investigations  Basic blood investigations  Prostate specific antigen  Urine analysis  Blood or protein look for renal tract pathology  Glucose look for diabetes Mellitus  Nitrates +/- leucocytes look for infection  Bladder/Void diary  Post-void bladder scan
  • 11. Voiding diary for 3 days Record to understand bladder function  Day + night frequency  Precipitating symptoms - coughing, laughing  Was there leaking of urine?  Urine volume lost involuntarily  Warning of full bladder and for how long?  How many pads were used during day and during night?  Were the pads damped or soaked in urine
  • 12. 3-day Bladder Chart Time Drink type Drink volume Volume of urine Leak Y/N?
  • 13. Bladder Chart  What is taken by person ◦ Caffeine containing drinks ◦ Carbonated drinks ◦ Medication  How much is taken by person  Too little fluids and too much fluids both can cause bladder problems
  • 14. Assessment of residual urine  Post-void bladder scan  With ageing post-void residual urine volume increases  In-out Catheterization  Higher incidence of urinary tract infection
  • 15. Red flags  Persisting bladder or urethral pain  Pelvic masses  Associated faecal incontinence  Suspected neurological disease  Symptoms of voiding difficulty  Suspected urogenital fistulae  Previous pelvic surgery  Previous pelvic irradiation
  • 16. Urodynamic testing  After lifestyle changes  Helps confirm detrusor instability  Voiding dysfunction due to uterine prolapse or benign prostatic enlargement  Previous surgery – BPH, stress incontinence
  • 18. Stress incontinence  Commoner in younger women, post-TURP  Small volumes of urine leaked  Precipitating factors – coughing, sneezing, bending  Symptoms mainly during daytime
  • 19. Lifestyle change  Weight reduction  Drink enough fluids  Avoid bladder irritants  Medication antipsychotics, alpha agonist  Caffeine  decaffeinated  Carbonated drinks  Alcohol
  • 20. Treatment for stress incontinence  Pelvic floor exercises at least for 3 months (level -1 evidence)  Electrical stimulation and biofeedback for women who cannot actively contract pelvic floor muscles  Duloxetine has evidence to improve symptoms  Transurethral bulking agents, Perineal sling, artificial urinary sphincter
  • 21. Urgency incontinence  Symptoms of urgency, hesitancy, poor stream  Daytime and night time frequency is similar  Larger volumes of urine is leaked  BPH, neurological conditions, medication
  • 22. Urgency incontinence  Bladder re-training for 6 months (level -1 evidence)  Antimuscarinic drugs  ß3 agonist - mirobegron  Transdermal oxybutinine is available  Need to take for about 4 weeks to see benefit  Botox therapy to the bladder
  • 23. Antimuscarinics  Oxybutynin  Solifenacin  Tolterodine  Side effects – confusion, dry mouth, urine retention
  • 24. Neurostimulation  Transcutaneous sacral nerve stimulation, transcutaneous posterior tibial nerve stimulation in OAB – no evidence  Percutaneous sacral nerve stimulation and percutaneous posterior tibial nerve stimulation - some success
  • 26.  Cause pain, bleeding, infection  Need repeated therapy Botox therapy
  • 27. Urinary catheters  Indications: ◦ Retention ◦ Skin wounds, pressure ulcers contaminated by urine ◦ Distress or disruption caused by bed and clothing changes  Intermittent urinary catheter  Indwelling urethral catheter  Indwelling suprapubic catheter
  • 28. Mixed incontinence  Treat pelvic floor exercise when stress incontinence symptoms are predominant problem  Bladder re-training when OAB symptoms are predominant  Treat the predominant symptom with medication when above has failed
  • 29. Nocturnal enuresis  More than 1/3 the total urine passed at night  Look for fluid overload - congestive cardiac failure  Limiting oral fluid intake after 1800 hours  Medication ◦ Diuretics around midday ◦ Desmopressin - sodium monitoring
  • 30. Oestrogen  Transvaginal oestrogen is beneficial to control OAB symptoms with vulvar atrophy.  Reduce recurrent urinary tract infection  Do not use systemic oestrogen
  • 31.  NICE has guidelines for management of urinary continence in women (CG 171) – November, 2015  NICE Guideline (NG123) April 2019

Editor's Notes

  1. Solifenacine, toltorodine