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COMMERCIALIZATION OF IARI
TECHNOLOGIES
PRAMOD KUMAR
Senior Scientist
ICAR – A step-by-step forward movement
Late-1960s Green Revolution, Seed Review Team(1967) (---- in the long run, the
breeders’ rights system would be desirable, particularly as a means of
encouraging private research)
1980s onwards Growth in other commodities, FAO Consultation, Quasim Committee,
NWGPL, SAI, MSSRF, Other NGOs; Several Institutional Reforms in ICAR
1988/89 New Policy on Seed Development, Breeder seed supply to public and
private seed companies
1993 ICAR gave the first draft on PPVFR Act, 2001 + continued support to
Development Deptts from NARS
1997 Rules and Guidelines on ‘Training, Consultancy, Contract Research /
Service – also in many Universities
1990s onwards Economic reforms (1991), Slow growth in agriculture from
1995 onwards More intensive reforms in NARS–NATP, NAIP
2006 IPR Guidelines in ICAR, Follow-up in Universities!
2007 onwards IPR-related awareness generation, Separate IPR Scheme
Our Intellectual Assets:
 Germplasm (IPR-enabled or otherwise,
free or facilitated access)
 Other products (e.g. vaccines,
biopesticides, equipments, software etc.)
 Technologies, processes, methodologies
 Information, know-how, publications
 Databases
 Services(e.g. training, consultancy,
contract research, contract service,
infrastructure facilities, liaison, other
facilitation/ partnerships)
ZTMC/
Zonal Institute
ZITMC
ITMU/
Institute/PD/Bureau/NRC
ITMC
95
25, 70
Facilitation for
Business Planning and
Development
Bottom-Up Approach
• Collective Decision Making
• Consultative Decision Making
• Outsourcing
5
ATMC/
ICAR HQ/
CTMC
Top-to-Bottom
• Decision
• Direction
• Execution
• Guidance
3-tier IP Management System
• Institute/ Zonal IP assets - Documentation
• Research Projects/Teams - Advisory Role w.r.t. IPM&TTC
• IP Management - IPR protection for technologies developed;
Maintenance of IPR Titles; Licences and Assignments (enhancing
capacity and HRD)
• Analyses of the commercial potential of IP assets
• Technology Transfer and commercialization
• Reporting and Monitoring
• Additional role of ZTMCs: Coordination of IPM&TTC activities
at the Zonal level with the ITMCs in respective zone and provide
expertise at the regional level
• Professional services: training, consultancy, contract research,
contract services - Extending Institute Expertise to Society
Function of ITMUs and ZTMCs
REVISITING
Requirements for Successful PPP
• Clear objectives that both parties agree. Without this at
some point there will be disagreement about intent
• Both parties contribute something other than money. If
it’s only cash, it’s a contract not a partnership.
• Clear definition of who does what. Separation is good, but
not absolutely essential.
• Single project plan with milestones.
• Pre-agreed clear governance mechanism, including
mechanism to resolve differences.
 Licensing of technologies to companies
(i) directly through MoU/Agreements or
(ii) through NRDC
 Institutional consultancy to public and private
organizations
 Contract research projects-Sponsored/Collaborative
 Contract service
Different Models for Technology
Commercialization at IARI
Types of Public-Private-Partnership Agreements
• Nonexclusive license for providing breeder seeds of parental
lines of hybrids
• Non exclusive licensing of gene construct/
• promoter and transgenic seed for its use or further
development by the company
• Agreement for providing breeder seeds of vegetables
varieties (open pollinated/hybrids) for production of
foundation, certified and truthfully labeled seeds by the
companies
• Non-exclusive license to use and practice the know how and
process of manufacture of the bio-formulations and products
• R&D based agreement with Non-Governmental Organizations
for crop improvements through sharing of material
• Agreement with farmer’s based organization for multiplication
of IARI varieties/hybrids seeds
Beneficiaries of PPP
• Other R&D institutions (experts-Technology Transfer
Organizations like NRDC, TIFAC, etc) helping in transfer of
technology;
• Patents Attorneys helping in legal vetting of the agreements;
• Design consultants helping in designing the package, shape
and size of the product and the form in which the product
should reach the consumers;
• Fabricators/ machinery manufacturers helping in designing
the proto-type of the machineries innovated for commercial
exploitation;
• Venture capitalists providing capital to the first generation
entrepreneurs who lack resources for taking up the
technology;
Beneficiaries of PPP
• Licensee/sub-licensee are the direct beneficiaries of the
technology generating income and employment
opportunities;
• Testing agencies providing services for testing the quality
and standard of the product produced through use of the
new technology;
• Market survey agencies provide the services for
assessment of the demand for the product, supply of the
inputs and also the location where the plant of firm should
be located, etc; and
• Certification agencies help in issue of certificates
following the proper procedure that testifies the quality and
standards of the products.
IARI Policy for Licensing
Varieties to retain their original trade mark- Pusa
For hybrid seed 4.5% royalty on net sale value + Cost of
Parental line seed
For major crop Varieties 1-2.5 % royalty on net sale value
For Vegetable seeds up to 10 % royalty
For gene/promoter Rs. 5 lakhs as license fee and an annual
royalty of 4 % on net sale value
For transgenic seed
material in T3/T4 stage
Rs 10 lakhs plus royalty as above
For custom made-parental
line
Rs 15 lakhs as license fees
For CMS line Rs 5 lakhs as license fee for transfer of
material (approx. 100 seeds for each line)
Request received from interested organization/companies
Company profile required
Technology brief from inventor
In-House Discussions
Approval by Institute Technology Management Committee (ITMC)
Industry invited for discussion with inventors and IARI officials
Terms and condition negotiations
Legal Vetting
Signing of MOU & transfer of material/ technologies
Procedural steps in commercialization of
technologies
Typical Elements of A License Agreement for
Commercialization
 Licensors responsibilities
 Licensee’s responsibilities
 Monitoring mechanism
 IP ownership issues
 Financial considerations
 Downpayment on execution of agreement
 Royalties
 Confidentiality
 Arbitration
Elements of A License Agreement for
Commercialization
Payment
form
Payment terms Objective
Down payment/
Lumpsum
On execution of
the
agreement/MoU
To cover licensor’s up-front
cost and ensure financial
commitment from the
licensee company
Royalty fees Percentage of
turnover created by
invention, payable
at fixed intervals
To share the risk between
inventor and licensee
company
Benefit sharing mechanism from
commercialized technologies
• Net revenue/benefit money available for sharing to be
determined as per clause 11.4.1 of “ICAR guidelines
for Intellectual Property Management and Technology
Transfer/Commercialization” effective since Oct, 2006.
• Net revenue/benefit money to be shared between
scientist/inventor and other staff as per clause 11.4.3
of above mentioned Guidelines.
 60 % of the available money: shared by scientist and his
team directly involved
25% of the available money: shared by
technical/supporting and administrative staffs
15 % of the available money: shared by other staff in the
Institute
• The originator of the work will be given 20%
more of the equal share than the other Co-PIs
• Scientist and technical staff who worked
earlier in the project and the present technical
staff will also be given share as per the
Guidelines
Contd..
Example of benefit sharing
Head of account Amount
Gross revenue A 1,00,000.0
Service tax @12.36% B 12360.0
Amount retained by ICAR @30% C 30000.0
Net revenue to be shared (A-B-C) X 57640.0
Scientist and other team members (60 % of X) X1 34584.0
Scientists involved (60 % of X1) 20750.4
Technical/supporting/administrative staff
involved (25% of X1)
8646.0
Other staff of the institute (15 % of X1) 5187.6
25% of X goes directly to the institutes account and 15% of X goes to ICAR
headquarters as per the Guidelines.
Beneficiaries of benefit sharing
PUSA RH-10 (2008-09)
(Total Revenue= Rs 77,47,402/- )
Sl.
No.
Particulars No. of
personnel
Amount (Rs) Average amount
(Rs )
1. Scientists 10 1517976 151798
2. Technical 8 421245 52656
3. Administrativ
e
9 105415 11713
4. Supporting 6 105830 17638
5. Accounts &
Audit Staff
25 127493 5099
6. Directorate
(including
ITMU)
23 252000 10957
Total 81 2529959 31234
• Varieties and Hybrids of different crops
• Bt genes & event 142
• Gene Constructs for virus resistance & their
detection kit
• Azadirachtin based formulations
• Pusa Hydrogel
• Pusa Fruit Drink
• Animal feed Block Making Machine
• Ground nut milk production
• Pomegranate Aril extractor
Technologies for Commercialization
Technology evaluation criteria (Mauria, 2009)
1. Clearly defined ownership position
2. Commercial status
3. Existing agreements
4. Familiarity to the user industry
5. Competitive position
6. Life expectancy
7. Existing standards or accepted norms
8. Existing public/private sector relationships
9. Presence of distribution system to control the technology
10. Nature of the industry
11. Economics of the technology
12. Quantum of technology as a critical factor
13. Capability required to bring the technology to the market place
Sl. No Technology Average
score
Ranking
1 Crop varieties 3.75 I
2 Pusa Hydrogel 3.67 II
3 Azadirachtin based formulations 3.65 III
4 Animal Feed Block Machine 3.44 IV
5 Gene constructs 3.33 V
6 Virus detection kit 3.13 VI
7 CMS Lines 3.29 VII
8 Biofertilizers 2.86 VIII
9 Pusa Fruit Drink 2.88 IX
10 Kalisena- Bio control agent 2.88 IX
11 Pusa Nemagel 2.87 X
12 Aqua-ferti-seed drill 2.69 XI
Prioritization of IARI technologies
Objectives
• To identify the potential technologies ready for
commercialization and develop into marketable technologies
and upscale them into viable agri-business under public
private partnership framework
• To develop a mechanism for transferring technology from
IARI to Public/Private sector using R & D backup of the
institute to help entrepreneurs
• To impart consultancy and training for creating prospective
entrepreneurs and value added man power
• To strengthen R & D focus of the institute towards more
applied research
ZONAL TECHNOLOGY MANAGEMENT & BUSINESS PLANNING
AND DEVELOPMENT UNIT, IARI, NEW DELHI.
What is technology business incubation?
• Business incubation is a dynamic process of business
enterprise development. Incubators nurture young
firms, helping them to survive and grow during the
startup period when they are most vulnerable.
• Incubators provide:
Hands-on management assistance
Access to financing
Business and technical support services
Shared office space, access to equipment
• Technology incubators nurture hi-tech start-ups and
present a technology-oriented variant of business
incubators
Infrastructure development
Cafeteria
Office Incubates space Library
Conference room
The Unit
MOL. LAB
Tissue Culture
facility
Equipments Procured
 PCR thermal cycler,
 Gel Electrophoresis Unit,
 Gel Doc System,
 Centrifuge
 Laminar Air Flow,
 Refrigerator
 Microwave oven,
 Deep freezers (-20 & -80),
 Autoclave,
 Water bath
 Incubator Shaker
Tissue culture facility
Laboratory
Institute- Industry Meet
Corporate participants - 13
No. of MoUs signed - 2
MoUs in process - 3
Participation in Stall Shows
Quality Seed Production through PPP – Organized by NSAI & IARI
No. of visitors to the stall- 50
Corporate membership earned – 5
Human Resource Development
Bio-pesticides/ Bio-fertilizers-May 14, 2009
Pusa Fruit Drinks- MAY 16, 2009
Animal Feed Block Formation Machine-May 19, 2009
Blue Green Algae Biofertilizer Technology – July 9-11 2009
Microbial Biopesticide Technology -Aug 31- Sept 3, 2009
Quality Seed Production in Vegetable Crops- October 26 – 31, 2009
Marker Assisted Selection for Crop Improvement – Feb 14-25, 2010
Entrepreneurship Development Programmes
Commercialized Technologies
through PPP -
Success Stories from IARI
Success story of Pusa-Basmati Rice
• Introduction of
PUSA 1121 as
Basmati rice
• Introduction of
PUSA RH10 as
Hybrid basmati
rice
100
110
120
130
140
150
160
170
Taraori
Basmati
Pusa Basmati
1
Pusa
Sugandh 2
Pusa RH 10
(Hybrid)
0
1
2
3
4
5
6
7Time Duration Vs Yield
• The World’s Finest Superfine Grain Aromatic Rice Hybrid
• Proven technology to break Yield Plateau
• Improves productivity by 15-20% over high yielding varieties
• Licensed to eighteen companies
• Royalty Rs 73 Lakh for 2009-2010
Pusa Hybrid Rice Pusa RH 10
Pusa RH 10
Early Hybrid with seed to seed maturity of 110-
115 days
Developed from Parental Lines :
6A (Male Sterile), 6B (Maintainer) and PRR 78
(Restorer)
Commercial Cultivation in irrigated ecosystem
Being early, saves 3 irrigations
On farmer’s field RH 10 yields approx. 28q/ acre
Commercialization of Pusa RH 10
1. IFSSA
2. Mahyco
3. Devgen
4. Advanta
5. Zuari
6. JK Seeds
7. Nath
8. Nuziveedu
9. Namdhari
10. Amreshwara
11. Bhavani Seeds
12. Yashoda Seeds
13. Rasi Seeds
14. Aatash Seed
15. Indo-American
16. Ganga Kaveri
17. Geo Technologies
Breeder : Foundation : F-1 Seed
1 Kg : 100 Kg : 10000 Kg
@ Rs. 80/Kg,10,000 Kg of F1 seed
will generate Rs. 8,00,000
Royalty (@ 4.5%) is Rs 36,000/Kg of
Breeder seed
Earning from Pusa RH 10 for 2008-2009 is Rs. 73 lakhs
Assumed Multiplication Rate
0
2000
4000
6000
8000
10000
12000
1990-91 1995-96 2000-01 2005-06 2006-07 2007-08 2008-09 2009-10
294
850
2148
3030 2792
4344
8000
12000
Value (Rs. in Crores)
PB-1 (1989)
PB1121 (2003)
Basmati Rice Export from India
Launching of a producer company “beejIndia Producer Company Ltd”
Incorporated under companies Act 1956.
Farmers of three clusters:
•Hapur &
•Bulandshahar (UP) and
•Chirawa (Rajasthan).
Venture: seed multiplication
Company- 50 farmers with
20 subscribed founding members.
8 member executive board
IARI as Advisory Director in the Executive Board.
Area- 100ha.
Crops: Wheat, Pulses, Oilseed, Potato and vegetable crops
The wheat variety HD 2967 simultaneously released for both North West and
East plain zones under timely sown irrigated conditions has been
commercialized through 34 seed companies covering areas of Haryana, Punjab,
Uttar Pradesh, Uttrakhand and Chhattisgarh.
It is a widely adaptable variety having adult plant resistance against prevalent
leaf rust and two most virulent races of yellow rust (Ug99).
This variety is likely to replace the ruling variety cultivated in both the zones and
thus would contribute significantly in enhancing the wheat production in the
country.
HD 2967 is better than the existing checks for chapati and bread making quality
also.
M/s Akash Seed
M/s Amar Seeds
M/s Asian Seeds
M/s Aujla Seeds
M/s beejIndia Prod Co Ltd
M/s Bhagati Seed Farm
M/s Bhatinda Seed Farm
M/s Bhatti Agri Seeds
M/s Bhatti Seeds Farm
M/s Bhawani Seeds
M/s Dhaliwal Seed Farms
M/s Dhan Nirankar Seed
M/s Hans Modern Agri. Seeds
M/s Harbir Agrotech
M/s Haryana Seeds Co
M/s Hygiene Kamboj Seed
farm
M/s ID Agri Seeds Pvt Ltd.
M/s Jaspreet Singh Gill
M/s Kamboj Export
M/s Kurukshetra Seeds Pvt Ltd
M/s Mehla Seed Farm
M/s Model Agritech India Ltd
M/s Navodaya Seed
M/s Nirankari Agri Seeds
M/s Parbhat Seed Traders
M/s Punjab Beej Co
M/s Randhawa Seed Syndicate
M/s Sahil Seeds
M/s Sahu Seed Farm
M/s Sandeep Seeds
M/s Sandhu Seed Farm
M/s Sekhon seed farm
M/s Vignette Hi-tech Seeds Co
THANK YOU
38
Sl.No Technologies Licensee
1 Biofertilizers M/S Sai Bio Organics
2 Biopesticide M/S Sai Bio Organics
3 Maize Hybrid PEEHM-5 M/s Sampoorna Seeds
4 Gene Construct - Event for TOSPO
resistance in Tomato
M/s Advanta India Ltd
5 PRH-10 IFSSA(Renewal of MoU which was signed on 7.04.2005)
Nirmal Seeds
Indo-American Hybrid Seeds Pvt ltd.
6 Pusa 1460 M/s GEO Biotechnologies India Pvt Ltd., Banglore
7 Pusa Fruit drink Alor Utshya
8 Modified Atmospheric packaging for
vegetables
Alor Utshya
9 Plant Virus detection kit Chromus Biotech
10 Animal Feed-block making machine Standard Hydraulics
Salient Achievements
IncubatEEs
Sl. No. Name Project
1 M/s. Abu Biotech In vitro Mass
propagation of Stevia
rubidiana
2 M/s. NutraHelix Biotech Pvt. Ltd. Probiotics
Virtual IncubatEES
Sl. No. Name Project
1 M/s. Neeraj Chandok Farm development
GENOTyping Services
Sl. No. Name Project
1 M/s. Noble Seeds Pvt. Ltd Screening of the parental and
hybrid lines for Tospo Virus
2 M/s. Sheel Biotech Genetic fidelity test in grafts of
grapes
IMPACTS
Technologies Commercialized
# of technologies
Licensed IARI 13
DMR 5
In pipeline NRCPB 1 (Mustard CMS line)
CPRI 1(Low sugar variety of potato)
VPKAS 1(QPM Line of Maize)
Revenue generated
Activity Revenue generated in Lakh `
Technology Licensing (IARI) 27.73
Technology Licensing (Zonal partner) 1.78
Trainings 9.00
Corporate membership 0.75
Incubation 0.25
Virtual Incubation 0.30
Genotyping services 0.20
Total 39. 98
CorporateMembers
41 Nos
TRAININGS/EDPs
Title of the program Date No. of
participants
EDP on Biopesticides/Bio-fertilizers 14 th May 2009 11
Pusa fruit drinks 15 th May 2009 7
Animal Feed Block formation machine 17 th May 2009 5
Blue Green Algae Biofertilizer technology 09-11th July 2009 13
Microbial Bio-pesticides 31st Aug-3rd Sept
2009
17
Quality Seed Production in Vegetable Crops :
An Entrepreneurial Perspective
26-31st Oct 2009 28
Marker Assisted Breeding for Crop
Improvement
14-24th February
2010
20
Production of Bio-fertilizer 6-13th Sept 2010 5
Production of Bio-pesticides 30th Aug-4th Sept
2010
1
Total 107
Setting up of Enterprise
Sl. No. Enterprizes Benefeciaries
1 Bio fertilizer unit Aman Sharma
Kamal Singh Chauhan
2 Bio agent unit Aman Sharma
3 Incubatee M/s.Abu biotech
M/s. NutraHelix Pvt. Ltd
4 Virus detection kit M/s. Chromus Biotech
5 Hydrogel M/s. Carborandum
6 Pusa Fruit Drink M/s. Alor Utshay
7 Animal Feed Block formation machine M/s. Standard hydraulics
Industry Institute Projects
Sl.No. Projects Beneficiaries
1 SIBRI Project awarded to the licensee companies
of Rs. 300 crore2 BIPP
IMPACT
Technology
commerciali
zation
IARI-14
ZONAL-5
Human
Resource
Development
EDPs-9
Participants-
107
Setting up
of enterprise
Biofertilizer
unit
Bioagent unit
Pusa fruit
Drinks
Hydrogel
Virus
detection kit
Joint
projects
awarded
SBIRI
(191.19L)-
Bejo Sheetal-
DBT & IARI
BIPP (700L)-
Advanta-DBT
& IARI
Revenue
Generated
Total- 42.98
lakhs
Zone North-I: ZTMC
1. Central Arid Zone Research Institute Jodhpur Rajasthan
2. Central Institute of Arid Horticulture Bikaner Rajasthan
3. Central Institute of Post Harvest Engg.
Techn.
Ludhiana Punjab
4. Central Institute of Temperate Horticulture Ranreth J&K
5. Central Potato Research Institute Shimla Himachal
Pradesh
6. Central Soil & Water Conservation
Research & Training Institute
Dehradun Uttarakhand
7. Central Soil Salinity Research Institute Karnal Haryana
8. Directorate of Maize Research New Delhi New Delhi
9. Directorate of Wheat Research Karnal Haryana
10. Indian Agricultural Research Institute New Delhi New Delhi
Zone North-I: ZTMC
11. Indian Agricultural Statistics Research Institute New Delhi New Delhi
12. Indian Institute of Vegetable Research Varanasi Uttar Pradesh
13. National Bureau of Plant Genetic Resources New Delhi New Delhi
14. National Centre of Agric. Eco. And Policy Res. New Delhi New Delhi
15. National Centre for Inte. Pest Management New Delhi New Delhi
16. National Research Centre for Mushroom Solan Hiachal Pradesh
17. National Research Centre for Rapeseed
Mustard
Bharatpur Rajasthan
18. National Research Centre on Plant
Biotechnology
New Delhi New Delhi
19. National Research Centre for Seed Spices Ajmer Rajasthan
20. Project Directorate for Cropping System Meerut Uttar Pradesh
21. Vivekanand Parvatiya Krishi Anushandhan
Sansthan
Almora Uttarakhand
IP ASSETS OF ZONAL INSTITUTES
Sl Institute IPR protectable for Non-IPR protectable for
Commercial Public Commercial Public
1 CAZRI, Jodhpur 16 2 23 19
2 CIAH, Bikaner
3 CIPHET,
Ludhiana
22 17 11 -
4 CITH, Rangreth - 8 - 4
5 CPRI, Shimla 17 57 3 -
6 CSW&CR&TI,
Dehradun
- - - 33
7 CSSRI, Karnal - 13 - 21
8 DMR, New Delhi 45 25 - -
9 DWR, New Delhi - 52 - 33
10 IARI, New Delhi 40 115 45 65
…..Continued
IP ASSETS OF ZONAL INSTITUTES
Sl Institute IPR protectable for Non-IPR protectable for
Commercial Public Commercial Public
11 IASRI, New Delhi - - - -
12 IIVR, Varanasi 30 - - -
13 NBPGR, New Delhi 3 3 - -
14 NCAP, New Delhi - - - -
15 NCIPM, New Delhi 2 - 3 -
16 NRC for Mushroom, Solan - - - 8
17 NRC Rapeseed, Bharatpur 5 - - -
18 NRCPB, New Delhi 3 44 - -
19 NRC Seed Spices, Ajmer 11 - - 9
20 PDFRS, Modipuram - - - 3
21 VPKAS, Almora 16 - 4 -
VPKAS, Almora • Vivek QPM-9
• Biopesticide
• Millet thresher
CPRI, Shimla • Bioformulation B5-a bio-fertilizer and bio-pesticide
• Mass multiplication in vitro for micro/mini tuber
• Potato custard powder and instant potato soup mix
CITH, Srinagar • Medium and high density orcharding in almond
• High density production technology in apple'
• Pea double cropping (Off season cultivation)
NBPGR, New Delhi • Ultra dessication technique for Cost effective seed storage
• PCR based detection of transgenes in GMOs
CIPHET, Ludhiana • Groundnut milk, curd, paneer
• Banana comb cutter
• Pomegranate aril extractor
NCIPM, New Delhi • Aerial Insect trap
• Egg cleaning device and Ultra violet chamber
• Field kit for mass multiplication of larval parasitoids in situ
Important Technologies from Zonal Institutes
…..Continued
IIVR, Varanasi • Kashi Bahar (VRH-1)-Bottle gourd hybrid
• Kashi Vaibhav (DVR-3) okra hybrid
• Kashi Amrit (DVRT-1)-Tomato variety
DWR, Karnal • Zero tillage
• IPM modules
• Dicoccum wheat rheumatic value
D Rapeseed
Mustard, Bharatpur
• NRCHB 506-Hybrid
• NRCHB 501-Variety
• NRCDR 2-Variety
PDFSR, Meerut • Laser leveller
• Site specific nutrient management
• Tubro and happy seed for residue management
CSSRI, Karnal • Salt tolerant high yielding fine grain Rice variety CSR 30
• Sub-surface drainage technology for the reclamation of
waterlogged saline soils
• Salt tolerant high yielding varieties of wheat (KRL 19)
and Indian mustard (CS56).
Bt genes & event 142
Shoot and Fruit
Borer
Tomato
Fruit borer
Tobacco
caterpillar
Bollworm
Gram podborer Rice Yellow
Stem borer Maize
stem borer
Maruca borer
Target Pests
CODON-
MODIFED
Bt-GENES
Bt-cry1Ac-F (Patent No.237912)
Bt-cry2Aa (Patent filed)
Bt-cry1Fa1 (Patent filed)
Bt-cry1Aabc
Bt-cry1A-J
Promoters
 CaMV 35 S
 Maize ubi
 Potato ubi3
 Pigeonpea rbcS
 Sucrose synthase
 Cotton Boll-specific
Bt Normal
FRUIT BORER RESISTANT
TRANSGENIC BRINJAL
Transgenic brinjal (cv. Pusa
Purple Long) expressing Bt-Cry1F
(Event 142).
Fruit damage in Control lines
varied from 43% to 47%.
Fruit damage in transgenic lines
ranged from 5% to 7%.
Bt-brinjal seed was transferred to
five Private Companies under PPP.
Technology for Introducing
Virus resistance and its
detection
(i) Gene Construct for Tomato leaf curl virus
S/S DNA Begomo Viruses
Using rep gene
sequences of Tomato
leaf curl virus for
broader coverage
Transgenic developed for conferring
Resistance to important viral diseases
of Tomato
(ii) Gene constructs for Groundnut bud necrosis virus
(GBNV) S/ S RNA Tospo Virus
RNAi constructs
Nucleo-capsid
protein & RNAi
suppressor gene
have been targeted
Developed
Groundnut
Transgenic
conferring
resistance to bud
necrosis virus
Development of transformants through co-cultivation using T-
rep gene of ToLCV and N gene of GBNV *
*N gene construct of
GBNV can also be used
for developing Tospo virus
resistance in Hot Pepper
Development of transformants through RNAi construct
using sequences from rep and N gene of ToLCV and GBNV
respectively
Diagnostic Kit for Detection of Viruses
Diagnostic Kit for detection of viruses
PCR based kit
Reliable, sensitive and quick detection method
Useful for production of clean planting material
Effective for detection of:
Citrus tristeza virus (CTV)
Citrus yellow mosaic virus (CYMV)
Indian citrus ringspot virus (ICRSV)
Citrus greening bacterium
CTV (~ 650 bp)
CYMV (~ 1 kb)
ICRSV (~300 bp)
M 1 2 3
~1 kb
~600 bp
~300 bp
Azadirachtin based Bio-pesticide
TECHNOLOGIES AVAILABLE FOR
Technical materials
i) Azadirachtin-A concentrates (20-25%)
ii) Azadirachtin-A enriched concentrates (40%, 60%)
iii) Azadirachtin-A, B & H (90%)
iv) Reduced azadirachtin concentrates (DAZA & TAZA)
Formulations
v) Heat, light and storage stable azadirachtin based neem products
vi) Azadirachtin enriched Soluble and Emulsifiable Concentrates
vii) Soluble and emulsifiable concentrates of reduced azadirachtins
viii) Slow release formulations of azadirachtin/hydro azadirachtins
(encapsulated and monolithic dispersions in polymeric matrix)
ix) Neem based seed coats
azadirachtin-A based products with insect control properties
• Process for preparation of aza-A
based stable neem biopesticides
• Heat, light and storage stable
• capable of stabilizing aza-A molecule
several-folds
• Performance, stability and bio-
efficacy of azadirachtin is enhanced
O
O
O
O
MeO2CO
O
AcO
MeO2C O
OH
OH
OH
H
Azadirachtin-A
HYDRO- AZADIRACHTINS (Indian Patent application no. 1126/DEL/2003)
O
O
H OH
O
C
O
CH3COO
CH3OOC
COOCH3
OH
OH
O
O
O
O
O
H OH
C
O
O
CH3COO
CH3OOC
COOCH3
OH
OH
O
O
O
O
O
H OH
C
O
O
CH3COO
CH3OOC
COOCH3
OH
OH
O
O
O
H2/Cat
H2/Cat
Azadirachtin-A
Dihydroazadirachtin-A Tetrahydroazadirachtin-A
 It has increased shelf and residual life
 It is as effective as azadirachtin at 20-50
ppm concentration against aphids, jassids,
fruit borer whitefly in okra, mustard,
tomato and cauliflower
 Safe to beneficial non-target organisms like
Coccinella septempunctata and Menochilus
sexmaculatus
 Safe to humans and the environment
(Toxicology data generared at ITRC
Lucknow)
Aza-A (EC and SL 0.15 to 5%)
THA (EC and SL 0.15 to 5%)
NEEM BASED NEW POLYMERIC SEED COATS
(Indian Patent Appln. 1746/DEL/ 2006)
 Natural or Synthetic polymer alone or in combination with neem
ingredient(s)
 Anionic / non-anionic surfactants (alone or blend)
 Polar / non-polar solvent (alone or blend)
 Powder or flow-able slurry
 Improve storability, germination, viability, plantability of seed
and/or vigor of plant
 Invaluable input in organic agriculture
NEEM EC & SL CONCENTRATES (Indian Patent Appln. 2416/DEL/2004)
TECHNOLOGY TRANSFER - STATUS
Azadirachtin Concentrate (Tech and formulations))
Sirinidhi Enterprise Gulbarga (2009)
Rallis India Limited, Bangalore (2009)
Reduced Azadirachtin Concentrate (Tech. and formulations)
Rallis India Limited, Bangalore (2009)
TERMS OF TRANSFER
Azadirachtin Concentrate
Sirinidhi Enterprises Gulbarga 15 lakh (Premium)
Reduced Azadirachtin Concentrate
Rallis India Limited, Bangalore 90 lakh (Premium)
Recurring Royalty : 3% (sale value of the products)
 An indigenous novel semi synthetic super-absorbent material
 Absorbs water 400 times and releases gradually
 Helps in overcoming moisture stress
 Low rates of soil application
1-3.0 kg ha-1 for nursery crops; 2.5-5.0 kg ha-1 for field crops
 Stability in soil for a minimum period of one year
 Licensed to five companies
PUSA HYDROGEL
Other benefits
 Improves physical properties of soils
 Improves % seed germination & emergence rate
 Improves root growth and density
 Promotes dense flowering and fruiting/ tillering
 Reduces nursery establishment period
 Delays onset of permanent wilting point
 Reduces leaching of herbicides/ fertilizers
PUSA Fruit Drinks
Bael Fruit Pulp (Juice)
Natural Colour
Natural flavour
No added sugar
Thermally processed
No Chemical Preservatives
(Class-II)
Base product for making
RTS drinks
Nectars
Fruit powder
Toffee
Shelf life 1 year at LT
Good for GI disorders
NOT TO BE KEPT AT
ROOM TEMPERATURE
ON OPENING.
PREFEREBLY TO BE
USED IMMEDIATELY
AFTER OPENING
Net Profit margin: > 50%
Aonla Pulp
Natural Colour
Natural flavour
No added sugar
Thermally processed
No Chemical Preservatives (Class-II)
Base product for making
RTS drinks
Nectars
Highly rich in Vitamin-C
Shelf life 1 year
NOT TO BE KEPT AT
ROOM TEMPERATURE
ON OPENING.
PREFEREBLY TO BE
USED IMMEDIATELY
AFTER OPENING.
Net Profit margin: > 50%
Whole Jamun Fruit Extract (Jamun Juice)
Natural Colour
Natural flavour
No added sugar
Thermally processed
Base product for making
RTS drinks
Nectars
High HYPOGLYCEMIC ACTIVITY
Shelf life 1 year
NOT TO BE KEPT AT
ROOM TEMPERATURE
ON OPENING.
PREFEREBLY TO BE
USED IMMEDIATELY
AFTER OPENING.
Net Profit margin: > 50%
RTS beverage
10-12.5% Pulp
No added Colour
No added Flavour
No class-II Chemical
Preservatives
Rich in Vit. C
Meets > 50% RDA
Thermally processed
Shelf life: 6-8 months
Net Profit margin:> 50%
Pusa Fruit Drinks- RTS Beverages
Aonla Drink
Jamun Drink
Bael Fruit Drink
Animal feed Block Making Machine
Need For Technology Development
Handling problem Transportation
problem
Storage Problems
Animal Feed Block Formation Machine
 A machine for compaction of
bio-materials
 Produces high density feed
blocks from roughage-based
crop residues
 Feed blocks can be
supplemented with molasses,
concentrates, minerals, salts,
etc
 Ease in handling of feed
materials and saving of labour
cost
 Saving of storage space and
transportation cost
Animal feed Block Making Machine
POMEGRANATE ARIL
EXTRACTION MACHINE
Salient features of hand tool
 Simple in design and fabrication
 30-45 % of arils get separated
during breaking of pomegranate &
rest are loosen
 Low and affordable cost
 Most suitable for domestic use,
juice vendors,
 Capacity to separate arils 5-7 kg
per hour
 Cost of tool is Rs. 500.00
 Time saving – approximately 50%
HAND TOOL FOR SEPARATION OF ARILS FROM POMEGRANATE
Whole fruit Separated Arils
CIPHET Pomegranate Aril Extractor (Industrial Model)
• Capacity – 500kg/h (35-40 fruits/minute)
• Efficiency – 94%
• The World’s Finest Superfine Grain Aromatic Rice Hybrid
• Proven technology to break Yield Plateau
• Improves productivity by 15-20% over high yielding varieties
• Licensed to fourteen companies
Pusa Hybrid Rice
Pusa RH 10
Pusa RH 10
Early Hybrid with seed to seed maturity of 110-115 days
Developed from Parental Lines :
6A (Male Sterile), 6B (Maintainer) and PRR 78 (Restorer)
Commercial Cultivation in irrigated ecosystem
Being early, saves 3 irrigations
On farmer’s field RH 10 yields approx. 28q/ acre
Gene Constructs for Developing Transgenics and
Diagnostic Kit for Detection of Viruses
Diagnostic Kit for detection of viruses
PCR based kit
Reliable, sensitive and quick detection method
Useful for production of clean planting material
Effective for detection of:
Citrus tristeza virus (CTV)
Citrus yellow mosaic virus (CYMV)
Indian citrus ringspot virus (ICRSV)
Citrus greening bacterium
CTV (~ 650 bp)
CYMV (~ 1 kb)
ICRSV (~300 bp)
M 1 2 3
~1 kb
~600 bp
~300 bp
Gene constructs developed are:
 Tomato Leave Curl Virus (ToLCV)
 Cry1Aabc and Cry1Fa1gene construct
 Transgenic material of brinjal seeds containing Cry1X gene
Coat protein gene construct of Tobacco Streak Virus (TSV)

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COMMERCIALIZING IARI TECHNOLOGIES

  • 2. ICAR – A step-by-step forward movement Late-1960s Green Revolution, Seed Review Team(1967) (---- in the long run, the breeders’ rights system would be desirable, particularly as a means of encouraging private research) 1980s onwards Growth in other commodities, FAO Consultation, Quasim Committee, NWGPL, SAI, MSSRF, Other NGOs; Several Institutional Reforms in ICAR 1988/89 New Policy on Seed Development, Breeder seed supply to public and private seed companies 1993 ICAR gave the first draft on PPVFR Act, 2001 + continued support to Development Deptts from NARS 1997 Rules and Guidelines on ‘Training, Consultancy, Contract Research / Service – also in many Universities 1990s onwards Economic reforms (1991), Slow growth in agriculture from 1995 onwards More intensive reforms in NARS–NATP, NAIP 2006 IPR Guidelines in ICAR, Follow-up in Universities! 2007 onwards IPR-related awareness generation, Separate IPR Scheme
  • 3. Our Intellectual Assets:  Germplasm (IPR-enabled or otherwise, free or facilitated access)  Other products (e.g. vaccines, biopesticides, equipments, software etc.)  Technologies, processes, methodologies  Information, know-how, publications  Databases  Services(e.g. training, consultancy, contract research, contract service, infrastructure facilities, liaison, other facilitation/ partnerships)
  • 4. ZTMC/ Zonal Institute ZITMC ITMU/ Institute/PD/Bureau/NRC ITMC 95 25, 70 Facilitation for Business Planning and Development Bottom-Up Approach • Collective Decision Making • Consultative Decision Making • Outsourcing 5 ATMC/ ICAR HQ/ CTMC Top-to-Bottom • Decision • Direction • Execution • Guidance 3-tier IP Management System
  • 5. • Institute/ Zonal IP assets - Documentation • Research Projects/Teams - Advisory Role w.r.t. IPM&TTC • IP Management - IPR protection for technologies developed; Maintenance of IPR Titles; Licences and Assignments (enhancing capacity and HRD) • Analyses of the commercial potential of IP assets • Technology Transfer and commercialization • Reporting and Monitoring • Additional role of ZTMCs: Coordination of IPM&TTC activities at the Zonal level with the ITMCs in respective zone and provide expertise at the regional level • Professional services: training, consultancy, contract research, contract services - Extending Institute Expertise to Society Function of ITMUs and ZTMCs
  • 7. Requirements for Successful PPP • Clear objectives that both parties agree. Without this at some point there will be disagreement about intent • Both parties contribute something other than money. If it’s only cash, it’s a contract not a partnership. • Clear definition of who does what. Separation is good, but not absolutely essential. • Single project plan with milestones. • Pre-agreed clear governance mechanism, including mechanism to resolve differences.
  • 8.  Licensing of technologies to companies (i) directly through MoU/Agreements or (ii) through NRDC  Institutional consultancy to public and private organizations  Contract research projects-Sponsored/Collaborative  Contract service Different Models for Technology Commercialization at IARI
  • 9. Types of Public-Private-Partnership Agreements • Nonexclusive license for providing breeder seeds of parental lines of hybrids • Non exclusive licensing of gene construct/ • promoter and transgenic seed for its use or further development by the company • Agreement for providing breeder seeds of vegetables varieties (open pollinated/hybrids) for production of foundation, certified and truthfully labeled seeds by the companies • Non-exclusive license to use and practice the know how and process of manufacture of the bio-formulations and products • R&D based agreement with Non-Governmental Organizations for crop improvements through sharing of material • Agreement with farmer’s based organization for multiplication of IARI varieties/hybrids seeds
  • 10. Beneficiaries of PPP • Other R&D institutions (experts-Technology Transfer Organizations like NRDC, TIFAC, etc) helping in transfer of technology; • Patents Attorneys helping in legal vetting of the agreements; • Design consultants helping in designing the package, shape and size of the product and the form in which the product should reach the consumers; • Fabricators/ machinery manufacturers helping in designing the proto-type of the machineries innovated for commercial exploitation; • Venture capitalists providing capital to the first generation entrepreneurs who lack resources for taking up the technology;
  • 11. Beneficiaries of PPP • Licensee/sub-licensee are the direct beneficiaries of the technology generating income and employment opportunities; • Testing agencies providing services for testing the quality and standard of the product produced through use of the new technology; • Market survey agencies provide the services for assessment of the demand for the product, supply of the inputs and also the location where the plant of firm should be located, etc; and • Certification agencies help in issue of certificates following the proper procedure that testifies the quality and standards of the products.
  • 12. IARI Policy for Licensing Varieties to retain their original trade mark- Pusa For hybrid seed 4.5% royalty on net sale value + Cost of Parental line seed For major crop Varieties 1-2.5 % royalty on net sale value For Vegetable seeds up to 10 % royalty For gene/promoter Rs. 5 lakhs as license fee and an annual royalty of 4 % on net sale value For transgenic seed material in T3/T4 stage Rs 10 lakhs plus royalty as above For custom made-parental line Rs 15 lakhs as license fees For CMS line Rs 5 lakhs as license fee for transfer of material (approx. 100 seeds for each line)
  • 13. Request received from interested organization/companies Company profile required Technology brief from inventor In-House Discussions Approval by Institute Technology Management Committee (ITMC) Industry invited for discussion with inventors and IARI officials Terms and condition negotiations Legal Vetting Signing of MOU & transfer of material/ technologies Procedural steps in commercialization of technologies
  • 14. Typical Elements of A License Agreement for Commercialization  Licensors responsibilities  Licensee’s responsibilities  Monitoring mechanism  IP ownership issues  Financial considerations  Downpayment on execution of agreement  Royalties  Confidentiality  Arbitration
  • 15. Elements of A License Agreement for Commercialization Payment form Payment terms Objective Down payment/ Lumpsum On execution of the agreement/MoU To cover licensor’s up-front cost and ensure financial commitment from the licensee company Royalty fees Percentage of turnover created by invention, payable at fixed intervals To share the risk between inventor and licensee company
  • 16. Benefit sharing mechanism from commercialized technologies • Net revenue/benefit money available for sharing to be determined as per clause 11.4.1 of “ICAR guidelines for Intellectual Property Management and Technology Transfer/Commercialization” effective since Oct, 2006. • Net revenue/benefit money to be shared between scientist/inventor and other staff as per clause 11.4.3 of above mentioned Guidelines.  60 % of the available money: shared by scientist and his team directly involved 25% of the available money: shared by technical/supporting and administrative staffs 15 % of the available money: shared by other staff in the Institute
  • 17. • The originator of the work will be given 20% more of the equal share than the other Co-PIs • Scientist and technical staff who worked earlier in the project and the present technical staff will also be given share as per the Guidelines Contd..
  • 18. Example of benefit sharing Head of account Amount Gross revenue A 1,00,000.0 Service tax @12.36% B 12360.0 Amount retained by ICAR @30% C 30000.0 Net revenue to be shared (A-B-C) X 57640.0 Scientist and other team members (60 % of X) X1 34584.0 Scientists involved (60 % of X1) 20750.4 Technical/supporting/administrative staff involved (25% of X1) 8646.0 Other staff of the institute (15 % of X1) 5187.6 25% of X goes directly to the institutes account and 15% of X goes to ICAR headquarters as per the Guidelines.
  • 19. Beneficiaries of benefit sharing PUSA RH-10 (2008-09) (Total Revenue= Rs 77,47,402/- ) Sl. No. Particulars No. of personnel Amount (Rs) Average amount (Rs ) 1. Scientists 10 1517976 151798 2. Technical 8 421245 52656 3. Administrativ e 9 105415 11713 4. Supporting 6 105830 17638 5. Accounts & Audit Staff 25 127493 5099 6. Directorate (including ITMU) 23 252000 10957 Total 81 2529959 31234
  • 20. • Varieties and Hybrids of different crops • Bt genes & event 142 • Gene Constructs for virus resistance & their detection kit • Azadirachtin based formulations • Pusa Hydrogel • Pusa Fruit Drink • Animal feed Block Making Machine • Ground nut milk production • Pomegranate Aril extractor Technologies for Commercialization
  • 21. Technology evaluation criteria (Mauria, 2009) 1. Clearly defined ownership position 2. Commercial status 3. Existing agreements 4. Familiarity to the user industry 5. Competitive position 6. Life expectancy 7. Existing standards or accepted norms 8. Existing public/private sector relationships 9. Presence of distribution system to control the technology 10. Nature of the industry 11. Economics of the technology 12. Quantum of technology as a critical factor 13. Capability required to bring the technology to the market place
  • 22. Sl. No Technology Average score Ranking 1 Crop varieties 3.75 I 2 Pusa Hydrogel 3.67 II 3 Azadirachtin based formulations 3.65 III 4 Animal Feed Block Machine 3.44 IV 5 Gene constructs 3.33 V 6 Virus detection kit 3.13 VI 7 CMS Lines 3.29 VII 8 Biofertilizers 2.86 VIII 9 Pusa Fruit Drink 2.88 IX 10 Kalisena- Bio control agent 2.88 IX 11 Pusa Nemagel 2.87 X 12 Aqua-ferti-seed drill 2.69 XI Prioritization of IARI technologies
  • 23. Objectives • To identify the potential technologies ready for commercialization and develop into marketable technologies and upscale them into viable agri-business under public private partnership framework • To develop a mechanism for transferring technology from IARI to Public/Private sector using R & D backup of the institute to help entrepreneurs • To impart consultancy and training for creating prospective entrepreneurs and value added man power • To strengthen R & D focus of the institute towards more applied research ZONAL TECHNOLOGY MANAGEMENT & BUSINESS PLANNING AND DEVELOPMENT UNIT, IARI, NEW DELHI.
  • 24. What is technology business incubation? • Business incubation is a dynamic process of business enterprise development. Incubators nurture young firms, helping them to survive and grow during the startup period when they are most vulnerable. • Incubators provide: Hands-on management assistance Access to financing Business and technical support services Shared office space, access to equipment • Technology incubators nurture hi-tech start-ups and present a technology-oriented variant of business incubators
  • 25. Infrastructure development Cafeteria Office Incubates space Library Conference room The Unit
  • 26. MOL. LAB Tissue Culture facility Equipments Procured  PCR thermal cycler,  Gel Electrophoresis Unit,  Gel Doc System,  Centrifuge  Laminar Air Flow,  Refrigerator  Microwave oven,  Deep freezers (-20 & -80),  Autoclave,  Water bath  Incubator Shaker Tissue culture facility Laboratory
  • 27. Institute- Industry Meet Corporate participants - 13 No. of MoUs signed - 2 MoUs in process - 3 Participation in Stall Shows Quality Seed Production through PPP – Organized by NSAI & IARI No. of visitors to the stall- 50 Corporate membership earned – 5
  • 28. Human Resource Development Bio-pesticides/ Bio-fertilizers-May 14, 2009 Pusa Fruit Drinks- MAY 16, 2009 Animal Feed Block Formation Machine-May 19, 2009 Blue Green Algae Biofertilizer Technology – July 9-11 2009 Microbial Biopesticide Technology -Aug 31- Sept 3, 2009 Quality Seed Production in Vegetable Crops- October 26 – 31, 2009 Marker Assisted Selection for Crop Improvement – Feb 14-25, 2010 Entrepreneurship Development Programmes
  • 29. Commercialized Technologies through PPP - Success Stories from IARI
  • 30. Success story of Pusa-Basmati Rice • Introduction of PUSA 1121 as Basmati rice • Introduction of PUSA RH10 as Hybrid basmati rice 100 110 120 130 140 150 160 170 Taraori Basmati Pusa Basmati 1 Pusa Sugandh 2 Pusa RH 10 (Hybrid) 0 1 2 3 4 5 6 7Time Duration Vs Yield
  • 31. • The World’s Finest Superfine Grain Aromatic Rice Hybrid • Proven technology to break Yield Plateau • Improves productivity by 15-20% over high yielding varieties • Licensed to eighteen companies • Royalty Rs 73 Lakh for 2009-2010 Pusa Hybrid Rice Pusa RH 10 Pusa RH 10 Early Hybrid with seed to seed maturity of 110- 115 days Developed from Parental Lines : 6A (Male Sterile), 6B (Maintainer) and PRR 78 (Restorer) Commercial Cultivation in irrigated ecosystem Being early, saves 3 irrigations On farmer’s field RH 10 yields approx. 28q/ acre
  • 32. Commercialization of Pusa RH 10 1. IFSSA 2. Mahyco 3. Devgen 4. Advanta 5. Zuari 6. JK Seeds 7. Nath 8. Nuziveedu 9. Namdhari 10. Amreshwara 11. Bhavani Seeds 12. Yashoda Seeds 13. Rasi Seeds 14. Aatash Seed 15. Indo-American 16. Ganga Kaveri 17. Geo Technologies Breeder : Foundation : F-1 Seed 1 Kg : 100 Kg : 10000 Kg @ Rs. 80/Kg,10,000 Kg of F1 seed will generate Rs. 8,00,000 Royalty (@ 4.5%) is Rs 36,000/Kg of Breeder seed Earning from Pusa RH 10 for 2008-2009 is Rs. 73 lakhs Assumed Multiplication Rate
  • 33.
  • 34. 0 2000 4000 6000 8000 10000 12000 1990-91 1995-96 2000-01 2005-06 2006-07 2007-08 2008-09 2009-10 294 850 2148 3030 2792 4344 8000 12000 Value (Rs. in Crores) PB-1 (1989) PB1121 (2003) Basmati Rice Export from India
  • 35. Launching of a producer company “beejIndia Producer Company Ltd” Incorporated under companies Act 1956. Farmers of three clusters: •Hapur & •Bulandshahar (UP) and •Chirawa (Rajasthan). Venture: seed multiplication Company- 50 farmers with 20 subscribed founding members. 8 member executive board IARI as Advisory Director in the Executive Board. Area- 100ha. Crops: Wheat, Pulses, Oilseed, Potato and vegetable crops
  • 36. The wheat variety HD 2967 simultaneously released for both North West and East plain zones under timely sown irrigated conditions has been commercialized through 34 seed companies covering areas of Haryana, Punjab, Uttar Pradesh, Uttrakhand and Chhattisgarh. It is a widely adaptable variety having adult plant resistance against prevalent leaf rust and two most virulent races of yellow rust (Ug99). This variety is likely to replace the ruling variety cultivated in both the zones and thus would contribute significantly in enhancing the wheat production in the country. HD 2967 is better than the existing checks for chapati and bread making quality also. M/s Akash Seed M/s Amar Seeds M/s Asian Seeds M/s Aujla Seeds M/s beejIndia Prod Co Ltd M/s Bhagati Seed Farm M/s Bhatinda Seed Farm M/s Bhatti Agri Seeds M/s Bhatti Seeds Farm M/s Bhawani Seeds M/s Dhaliwal Seed Farms M/s Dhan Nirankar Seed M/s Hans Modern Agri. Seeds M/s Harbir Agrotech M/s Haryana Seeds Co M/s Hygiene Kamboj Seed farm M/s ID Agri Seeds Pvt Ltd. M/s Jaspreet Singh Gill M/s Kamboj Export M/s Kurukshetra Seeds Pvt Ltd M/s Mehla Seed Farm M/s Model Agritech India Ltd M/s Navodaya Seed M/s Nirankari Agri Seeds M/s Parbhat Seed Traders M/s Punjab Beej Co M/s Randhawa Seed Syndicate M/s Sahil Seeds M/s Sahu Seed Farm M/s Sandeep Seeds M/s Sandhu Seed Farm M/s Sekhon seed farm M/s Vignette Hi-tech Seeds Co
  • 38. 38 Sl.No Technologies Licensee 1 Biofertilizers M/S Sai Bio Organics 2 Biopesticide M/S Sai Bio Organics 3 Maize Hybrid PEEHM-5 M/s Sampoorna Seeds 4 Gene Construct - Event for TOSPO resistance in Tomato M/s Advanta India Ltd 5 PRH-10 IFSSA(Renewal of MoU which was signed on 7.04.2005) Nirmal Seeds Indo-American Hybrid Seeds Pvt ltd. 6 Pusa 1460 M/s GEO Biotechnologies India Pvt Ltd., Banglore 7 Pusa Fruit drink Alor Utshya 8 Modified Atmospheric packaging for vegetables Alor Utshya 9 Plant Virus detection kit Chromus Biotech 10 Animal Feed-block making machine Standard Hydraulics Salient Achievements
  • 39. IncubatEEs Sl. No. Name Project 1 M/s. Abu Biotech In vitro Mass propagation of Stevia rubidiana 2 M/s. NutraHelix Biotech Pvt. Ltd. Probiotics Virtual IncubatEES Sl. No. Name Project 1 M/s. Neeraj Chandok Farm development GENOTyping Services Sl. No. Name Project 1 M/s. Noble Seeds Pvt. Ltd Screening of the parental and hybrid lines for Tospo Virus 2 M/s. Sheel Biotech Genetic fidelity test in grafts of grapes
  • 40. IMPACTS Technologies Commercialized # of technologies Licensed IARI 13 DMR 5 In pipeline NRCPB 1 (Mustard CMS line) CPRI 1(Low sugar variety of potato) VPKAS 1(QPM Line of Maize) Revenue generated Activity Revenue generated in Lakh ` Technology Licensing (IARI) 27.73 Technology Licensing (Zonal partner) 1.78 Trainings 9.00 Corporate membership 0.75 Incubation 0.25 Virtual Incubation 0.30 Genotyping services 0.20 Total 39. 98
  • 42. TRAININGS/EDPs Title of the program Date No. of participants EDP on Biopesticides/Bio-fertilizers 14 th May 2009 11 Pusa fruit drinks 15 th May 2009 7 Animal Feed Block formation machine 17 th May 2009 5 Blue Green Algae Biofertilizer technology 09-11th July 2009 13 Microbial Bio-pesticides 31st Aug-3rd Sept 2009 17 Quality Seed Production in Vegetable Crops : An Entrepreneurial Perspective 26-31st Oct 2009 28 Marker Assisted Breeding for Crop Improvement 14-24th February 2010 20 Production of Bio-fertilizer 6-13th Sept 2010 5 Production of Bio-pesticides 30th Aug-4th Sept 2010 1 Total 107
  • 43. Setting up of Enterprise Sl. No. Enterprizes Benefeciaries 1 Bio fertilizer unit Aman Sharma Kamal Singh Chauhan 2 Bio agent unit Aman Sharma 3 Incubatee M/s.Abu biotech M/s. NutraHelix Pvt. Ltd 4 Virus detection kit M/s. Chromus Biotech 5 Hydrogel M/s. Carborandum 6 Pusa Fruit Drink M/s. Alor Utshay 7 Animal Feed Block formation machine M/s. Standard hydraulics Industry Institute Projects Sl.No. Projects Beneficiaries 1 SIBRI Project awarded to the licensee companies of Rs. 300 crore2 BIPP
  • 44. IMPACT Technology commerciali zation IARI-14 ZONAL-5 Human Resource Development EDPs-9 Participants- 107 Setting up of enterprise Biofertilizer unit Bioagent unit Pusa fruit Drinks Hydrogel Virus detection kit Joint projects awarded SBIRI (191.19L)- Bejo Sheetal- DBT & IARI BIPP (700L)- Advanta-DBT & IARI Revenue Generated Total- 42.98 lakhs
  • 45. Zone North-I: ZTMC 1. Central Arid Zone Research Institute Jodhpur Rajasthan 2. Central Institute of Arid Horticulture Bikaner Rajasthan 3. Central Institute of Post Harvest Engg. Techn. Ludhiana Punjab 4. Central Institute of Temperate Horticulture Ranreth J&K 5. Central Potato Research Institute Shimla Himachal Pradesh 6. Central Soil & Water Conservation Research & Training Institute Dehradun Uttarakhand 7. Central Soil Salinity Research Institute Karnal Haryana 8. Directorate of Maize Research New Delhi New Delhi 9. Directorate of Wheat Research Karnal Haryana 10. Indian Agricultural Research Institute New Delhi New Delhi
  • 46. Zone North-I: ZTMC 11. Indian Agricultural Statistics Research Institute New Delhi New Delhi 12. Indian Institute of Vegetable Research Varanasi Uttar Pradesh 13. National Bureau of Plant Genetic Resources New Delhi New Delhi 14. National Centre of Agric. Eco. And Policy Res. New Delhi New Delhi 15. National Centre for Inte. Pest Management New Delhi New Delhi 16. National Research Centre for Mushroom Solan Hiachal Pradesh 17. National Research Centre for Rapeseed Mustard Bharatpur Rajasthan 18. National Research Centre on Plant Biotechnology New Delhi New Delhi 19. National Research Centre for Seed Spices Ajmer Rajasthan 20. Project Directorate for Cropping System Meerut Uttar Pradesh 21. Vivekanand Parvatiya Krishi Anushandhan Sansthan Almora Uttarakhand
  • 47. IP ASSETS OF ZONAL INSTITUTES Sl Institute IPR protectable for Non-IPR protectable for Commercial Public Commercial Public 1 CAZRI, Jodhpur 16 2 23 19 2 CIAH, Bikaner 3 CIPHET, Ludhiana 22 17 11 - 4 CITH, Rangreth - 8 - 4 5 CPRI, Shimla 17 57 3 - 6 CSW&CR&TI, Dehradun - - - 33 7 CSSRI, Karnal - 13 - 21 8 DMR, New Delhi 45 25 - - 9 DWR, New Delhi - 52 - 33 10 IARI, New Delhi 40 115 45 65 …..Continued
  • 48. IP ASSETS OF ZONAL INSTITUTES Sl Institute IPR protectable for Non-IPR protectable for Commercial Public Commercial Public 11 IASRI, New Delhi - - - - 12 IIVR, Varanasi 30 - - - 13 NBPGR, New Delhi 3 3 - - 14 NCAP, New Delhi - - - - 15 NCIPM, New Delhi 2 - 3 - 16 NRC for Mushroom, Solan - - - 8 17 NRC Rapeseed, Bharatpur 5 - - - 18 NRCPB, New Delhi 3 44 - - 19 NRC Seed Spices, Ajmer 11 - - 9 20 PDFRS, Modipuram - - - 3 21 VPKAS, Almora 16 - 4 -
  • 49. VPKAS, Almora • Vivek QPM-9 • Biopesticide • Millet thresher CPRI, Shimla • Bioformulation B5-a bio-fertilizer and bio-pesticide • Mass multiplication in vitro for micro/mini tuber • Potato custard powder and instant potato soup mix CITH, Srinagar • Medium and high density orcharding in almond • High density production technology in apple' • Pea double cropping (Off season cultivation) NBPGR, New Delhi • Ultra dessication technique for Cost effective seed storage • PCR based detection of transgenes in GMOs CIPHET, Ludhiana • Groundnut milk, curd, paneer • Banana comb cutter • Pomegranate aril extractor NCIPM, New Delhi • Aerial Insect trap • Egg cleaning device and Ultra violet chamber • Field kit for mass multiplication of larval parasitoids in situ Important Technologies from Zonal Institutes …..Continued
  • 50. IIVR, Varanasi • Kashi Bahar (VRH-1)-Bottle gourd hybrid • Kashi Vaibhav (DVR-3) okra hybrid • Kashi Amrit (DVRT-1)-Tomato variety DWR, Karnal • Zero tillage • IPM modules • Dicoccum wheat rheumatic value D Rapeseed Mustard, Bharatpur • NRCHB 506-Hybrid • NRCHB 501-Variety • NRCDR 2-Variety PDFSR, Meerut • Laser leveller • Site specific nutrient management • Tubro and happy seed for residue management CSSRI, Karnal • Salt tolerant high yielding fine grain Rice variety CSR 30 • Sub-surface drainage technology for the reclamation of waterlogged saline soils • Salt tolerant high yielding varieties of wheat (KRL 19) and Indian mustard (CS56).
  • 51. Bt genes & event 142
  • 52. Shoot and Fruit Borer Tomato Fruit borer Tobacco caterpillar Bollworm Gram podborer Rice Yellow Stem borer Maize stem borer Maruca borer Target Pests
  • 53. CODON- MODIFED Bt-GENES Bt-cry1Ac-F (Patent No.237912) Bt-cry2Aa (Patent filed) Bt-cry1Fa1 (Patent filed) Bt-cry1Aabc Bt-cry1A-J Promoters  CaMV 35 S  Maize ubi  Potato ubi3  Pigeonpea rbcS  Sucrose synthase  Cotton Boll-specific
  • 54. Bt Normal FRUIT BORER RESISTANT TRANSGENIC BRINJAL Transgenic brinjal (cv. Pusa Purple Long) expressing Bt-Cry1F (Event 142). Fruit damage in Control lines varied from 43% to 47%. Fruit damage in transgenic lines ranged from 5% to 7%. Bt-brinjal seed was transferred to five Private Companies under PPP.
  • 55. Technology for Introducing Virus resistance and its detection
  • 56. (i) Gene Construct for Tomato leaf curl virus S/S DNA Begomo Viruses Using rep gene sequences of Tomato leaf curl virus for broader coverage Transgenic developed for conferring Resistance to important viral diseases of Tomato
  • 57. (ii) Gene constructs for Groundnut bud necrosis virus (GBNV) S/ S RNA Tospo Virus RNAi constructs Nucleo-capsid protein & RNAi suppressor gene have been targeted Developed Groundnut Transgenic conferring resistance to bud necrosis virus
  • 58. Development of transformants through co-cultivation using T- rep gene of ToLCV and N gene of GBNV * *N gene construct of GBNV can also be used for developing Tospo virus resistance in Hot Pepper
  • 59. Development of transformants through RNAi construct using sequences from rep and N gene of ToLCV and GBNV respectively
  • 60. Diagnostic Kit for Detection of Viruses Diagnostic Kit for detection of viruses PCR based kit Reliable, sensitive and quick detection method Useful for production of clean planting material Effective for detection of: Citrus tristeza virus (CTV) Citrus yellow mosaic virus (CYMV) Indian citrus ringspot virus (ICRSV) Citrus greening bacterium CTV (~ 650 bp) CYMV (~ 1 kb) ICRSV (~300 bp) M 1 2 3 ~1 kb ~600 bp ~300 bp
  • 62. TECHNOLOGIES AVAILABLE FOR Technical materials i) Azadirachtin-A concentrates (20-25%) ii) Azadirachtin-A enriched concentrates (40%, 60%) iii) Azadirachtin-A, B & H (90%) iv) Reduced azadirachtin concentrates (DAZA & TAZA) Formulations v) Heat, light and storage stable azadirachtin based neem products vi) Azadirachtin enriched Soluble and Emulsifiable Concentrates vii) Soluble and emulsifiable concentrates of reduced azadirachtins viii) Slow release formulations of azadirachtin/hydro azadirachtins (encapsulated and monolithic dispersions in polymeric matrix) ix) Neem based seed coats
  • 63. azadirachtin-A based products with insect control properties • Process for preparation of aza-A based stable neem biopesticides • Heat, light and storage stable • capable of stabilizing aza-A molecule several-folds • Performance, stability and bio- efficacy of azadirachtin is enhanced O O O O MeO2CO O AcO MeO2C O OH OH OH H Azadirachtin-A HYDRO- AZADIRACHTINS (Indian Patent application no. 1126/DEL/2003) O O H OH O C O CH3COO CH3OOC COOCH3 OH OH O O O O O H OH C O O CH3COO CH3OOC COOCH3 OH OH O O O O O H OH C O O CH3COO CH3OOC COOCH3 OH OH O O O H2/Cat H2/Cat Azadirachtin-A Dihydroazadirachtin-A Tetrahydroazadirachtin-A  It has increased shelf and residual life  It is as effective as azadirachtin at 20-50 ppm concentration against aphids, jassids, fruit borer whitefly in okra, mustard, tomato and cauliflower  Safe to beneficial non-target organisms like Coccinella septempunctata and Menochilus sexmaculatus  Safe to humans and the environment (Toxicology data generared at ITRC Lucknow)
  • 64. Aza-A (EC and SL 0.15 to 5%) THA (EC and SL 0.15 to 5%) NEEM BASED NEW POLYMERIC SEED COATS (Indian Patent Appln. 1746/DEL/ 2006)  Natural or Synthetic polymer alone or in combination with neem ingredient(s)  Anionic / non-anionic surfactants (alone or blend)  Polar / non-polar solvent (alone or blend)  Powder or flow-able slurry  Improve storability, germination, viability, plantability of seed and/or vigor of plant  Invaluable input in organic agriculture NEEM EC & SL CONCENTRATES (Indian Patent Appln. 2416/DEL/2004)
  • 65. TECHNOLOGY TRANSFER - STATUS Azadirachtin Concentrate (Tech and formulations)) Sirinidhi Enterprise Gulbarga (2009) Rallis India Limited, Bangalore (2009) Reduced Azadirachtin Concentrate (Tech. and formulations) Rallis India Limited, Bangalore (2009) TERMS OF TRANSFER Azadirachtin Concentrate Sirinidhi Enterprises Gulbarga 15 lakh (Premium) Reduced Azadirachtin Concentrate Rallis India Limited, Bangalore 90 lakh (Premium) Recurring Royalty : 3% (sale value of the products)
  • 66.  An indigenous novel semi synthetic super-absorbent material  Absorbs water 400 times and releases gradually  Helps in overcoming moisture stress  Low rates of soil application 1-3.0 kg ha-1 for nursery crops; 2.5-5.0 kg ha-1 for field crops  Stability in soil for a minimum period of one year  Licensed to five companies PUSA HYDROGEL Other benefits  Improves physical properties of soils  Improves % seed germination & emergence rate  Improves root growth and density  Promotes dense flowering and fruiting/ tillering  Reduces nursery establishment period  Delays onset of permanent wilting point  Reduces leaching of herbicides/ fertilizers
  • 68. Bael Fruit Pulp (Juice) Natural Colour Natural flavour No added sugar Thermally processed No Chemical Preservatives (Class-II) Base product for making RTS drinks Nectars Fruit powder Toffee Shelf life 1 year at LT Good for GI disorders NOT TO BE KEPT AT ROOM TEMPERATURE ON OPENING. PREFEREBLY TO BE USED IMMEDIATELY AFTER OPENING Net Profit margin: > 50%
  • 69. Aonla Pulp Natural Colour Natural flavour No added sugar Thermally processed No Chemical Preservatives (Class-II) Base product for making RTS drinks Nectars Highly rich in Vitamin-C Shelf life 1 year NOT TO BE KEPT AT ROOM TEMPERATURE ON OPENING. PREFEREBLY TO BE USED IMMEDIATELY AFTER OPENING. Net Profit margin: > 50%
  • 70. Whole Jamun Fruit Extract (Jamun Juice) Natural Colour Natural flavour No added sugar Thermally processed Base product for making RTS drinks Nectars High HYPOGLYCEMIC ACTIVITY Shelf life 1 year NOT TO BE KEPT AT ROOM TEMPERATURE ON OPENING. PREFEREBLY TO BE USED IMMEDIATELY AFTER OPENING. Net Profit margin: > 50%
  • 71. RTS beverage 10-12.5% Pulp No added Colour No added Flavour No class-II Chemical Preservatives Rich in Vit. C Meets > 50% RDA Thermally processed Shelf life: 6-8 months Net Profit margin:> 50% Pusa Fruit Drinks- RTS Beverages Aonla Drink Jamun Drink Bael Fruit Drink
  • 72. Animal feed Block Making Machine
  • 73. Need For Technology Development Handling problem Transportation problem Storage Problems
  • 74. Animal Feed Block Formation Machine
  • 75.  A machine for compaction of bio-materials  Produces high density feed blocks from roughage-based crop residues  Feed blocks can be supplemented with molasses, concentrates, minerals, salts, etc  Ease in handling of feed materials and saving of labour cost  Saving of storage space and transportation cost Animal feed Block Making Machine
  • 77. Salient features of hand tool  Simple in design and fabrication  30-45 % of arils get separated during breaking of pomegranate & rest are loosen  Low and affordable cost  Most suitable for domestic use, juice vendors,  Capacity to separate arils 5-7 kg per hour  Cost of tool is Rs. 500.00  Time saving – approximately 50% HAND TOOL FOR SEPARATION OF ARILS FROM POMEGRANATE
  • 78. Whole fruit Separated Arils CIPHET Pomegranate Aril Extractor (Industrial Model) • Capacity – 500kg/h (35-40 fruits/minute) • Efficiency – 94%
  • 79. • The World’s Finest Superfine Grain Aromatic Rice Hybrid • Proven technology to break Yield Plateau • Improves productivity by 15-20% over high yielding varieties • Licensed to fourteen companies Pusa Hybrid Rice Pusa RH 10 Pusa RH 10 Early Hybrid with seed to seed maturity of 110-115 days Developed from Parental Lines : 6A (Male Sterile), 6B (Maintainer) and PRR 78 (Restorer) Commercial Cultivation in irrigated ecosystem Being early, saves 3 irrigations On farmer’s field RH 10 yields approx. 28q/ acre
  • 80. Gene Constructs for Developing Transgenics and Diagnostic Kit for Detection of Viruses Diagnostic Kit for detection of viruses PCR based kit Reliable, sensitive and quick detection method Useful for production of clean planting material Effective for detection of: Citrus tristeza virus (CTV) Citrus yellow mosaic virus (CYMV) Indian citrus ringspot virus (ICRSV) Citrus greening bacterium CTV (~ 650 bp) CYMV (~ 1 kb) ICRSV (~300 bp) M 1 2 3 ~1 kb ~600 bp ~300 bp Gene constructs developed are:  Tomato Leave Curl Virus (ToLCV)  Cry1Aabc and Cry1Fa1gene construct  Transgenic material of brinjal seeds containing Cry1X gene Coat protein gene construct of Tobacco Streak Virus (TSV)