Colorants are ingredients that impart or alter the color of cosmetic products. Dyes dissolve to color the skin, while pigments coat the skin with an insoluble powder film. Colorants are used to make cosmetics attractive and are classified as organic or inorganic. Common inorganic pigments include chromium dioxides and iron oxides. Titanium dioxide and zinc oxide are widely used white pigments. Antioxidants like vitamins C and E, along with coenzyme Q10, protect skin from free radicals.
Shampoo
Human Hair Structure
Introduction
Shampoo is a hair care product that is used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant particles that gradually build up in hair.
Introduction
Ideal Properties
Functions of Shampoo
Classification
Classification
Based on Appearance:
Powder Shampoos
Liquid Shampoos or Lotion
Gel Shampoos or Solid Cream
Classification
Classification
II. Based on Use or Function:
Conditioning Shampoos
Antidandruff and Therapeutic
Baby
Balancing
Clarifying
Classification
III. Based on Origin:
Compositions
Shampoos are typically composed of 10 to 30 ingredients.
Several types of ingredients are particularly important, including “Surfactants" that aid in cleansing and lathering.
“Conditioners" and “Active ingredients" that affect the hair and scalp.
“Additives" that stabilize the product.
Compositions
Compositions
Compositions
Compositions
Manufacturing Process
Some pearlising agents are waxy solids at ambient temperature and require melting in a drum oven or similar before use.
Demineralised water is most commonly used in order to minimise contamination of the product.
No further processing is required after blending, and the product may be packed off directly from the mixing vessel.
Manufacturing Process
For preparing liquid shampoo,
Triethanalamine lauvyl sulfate,
stearic acid are heated to about 650C.
Water & preservatives are also heated to 650C.
Both the solutions are mixed together and then cooled.
Perfumes are added after that. The shampoo thus prepared is bottled by automatic bottle filling machine.
Quality Control Tests
a)Foam Stability
Cylinder shake method was used for determining foaming ability.
50ml of the 1% shampoo solution was put into a 250ml graduated cylinder and cover the cylinder with hand and shaken for 10 times. The total volumes of the foam contents after 1 minute shaking were recorded. The foam volume was calculated. Foam should retain for atleast 5mins.
Foam Stability = V2-V1
Quality Control Tests
b)Skin – irritation Test:
Draize test in Rabbits where a patch test technique is used on the intact skin of Albino Rabbits.
A set of 6Rabbits used for testing each material.
Shampoos should be tested only for a short duration thatis,not more than(NMT)4hours as these products come in contact with skin only for a short duration.
These preparations are diluted between concentrations of 8 to 10%.
Quality Control Tests
c)Wetting Action:
Canvas disk is used, is one inch in diameter is floated on the surface of a solution and the time required for it to sink is measured accurately.
Quality Control Tests
d)Viscosity:
Is determined using Brookefield Viscometer.
100ml of shampoo is taken in a beaker and spindle is dipped in it for about 5min and then reading is taken.
Quality Control
Manicure preparations - nail polishes, nail enamel removers, nail art (definitions, formulations, method of preparation, pictures, evaluations) Dosage form
Join Phil Masiello, Co-Founder and CEO of 800Razors.com, Caroline Riddle, Partner Marketing Manager of Windsor Circle, and Matthew Ramos, Director of Customer Success at WhatCounts as they dive into the strategy 800Razors.com has employed to increase repeat buyers by 81%.
Global Oleochemicals Market (By Application, Type, Raw Material, Region): Opportunities and Forecasts (2016-2021)
(By Raw Material -Tropical Oil, Soft Oil, Animal Fat; By Type - Fatty Acid, Fatty Alcohol, Glycerine; By Application- Pharmaceutical, Food & Beverages, Detergents & Soaps, Personal Care & Cosmetics; By Region – APAC, Europe, RoW; By Country- Malaysia, Indonesia, India, China)
www.azothanalytics.com/report/healthcare-pharma/global-oleochemicals-market-by-application-type-raw-material-region-opportunities- and-forecasts-2016-2021
Shampoo
Human Hair Structure
Introduction
Shampoo is a hair care product that is used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant particles that gradually build up in hair.
Introduction
Ideal Properties
Functions of Shampoo
Classification
Classification
Based on Appearance:
Powder Shampoos
Liquid Shampoos or Lotion
Gel Shampoos or Solid Cream
Classification
Classification
II. Based on Use or Function:
Conditioning Shampoos
Antidandruff and Therapeutic
Baby
Balancing
Clarifying
Classification
III. Based on Origin:
Compositions
Shampoos are typically composed of 10 to 30 ingredients.
Several types of ingredients are particularly important, including “Surfactants" that aid in cleansing and lathering.
“Conditioners" and “Active ingredients" that affect the hair and scalp.
“Additives" that stabilize the product.
Compositions
Compositions
Compositions
Compositions
Manufacturing Process
Some pearlising agents are waxy solids at ambient temperature and require melting in a drum oven or similar before use.
Demineralised water is most commonly used in order to minimise contamination of the product.
No further processing is required after blending, and the product may be packed off directly from the mixing vessel.
Manufacturing Process
For preparing liquid shampoo,
Triethanalamine lauvyl sulfate,
stearic acid are heated to about 650C.
Water & preservatives are also heated to 650C.
Both the solutions are mixed together and then cooled.
Perfumes are added after that. The shampoo thus prepared is bottled by automatic bottle filling machine.
Quality Control Tests
a)Foam Stability
Cylinder shake method was used for determining foaming ability.
50ml of the 1% shampoo solution was put into a 250ml graduated cylinder and cover the cylinder with hand and shaken for 10 times. The total volumes of the foam contents after 1 minute shaking were recorded. The foam volume was calculated. Foam should retain for atleast 5mins.
Foam Stability = V2-V1
Quality Control Tests
b)Skin – irritation Test:
Draize test in Rabbits where a patch test technique is used on the intact skin of Albino Rabbits.
A set of 6Rabbits used for testing each material.
Shampoos should be tested only for a short duration thatis,not more than(NMT)4hours as these products come in contact with skin only for a short duration.
These preparations are diluted between concentrations of 8 to 10%.
Quality Control Tests
c)Wetting Action:
Canvas disk is used, is one inch in diameter is floated on the surface of a solution and the time required for it to sink is measured accurately.
Quality Control Tests
d)Viscosity:
Is determined using Brookefield Viscometer.
100ml of shampoo is taken in a beaker and spindle is dipped in it for about 5min and then reading is taken.
Quality Control
Manicure preparations - nail polishes, nail enamel removers, nail art (definitions, formulations, method of preparation, pictures, evaluations) Dosage form
Join Phil Masiello, Co-Founder and CEO of 800Razors.com, Caroline Riddle, Partner Marketing Manager of Windsor Circle, and Matthew Ramos, Director of Customer Success at WhatCounts as they dive into the strategy 800Razors.com has employed to increase repeat buyers by 81%.
Global Oleochemicals Market (By Application, Type, Raw Material, Region): Opportunities and Forecasts (2016-2021)
(By Raw Material -Tropical Oil, Soft Oil, Animal Fat; By Type - Fatty Acid, Fatty Alcohol, Glycerine; By Application- Pharmaceutical, Food & Beverages, Detergents & Soaps, Personal Care & Cosmetics; By Region – APAC, Europe, RoW; By Country- Malaysia, Indonesia, India, China)
www.azothanalytics.com/report/healthcare-pharma/global-oleochemicals-market-by-application-type-raw-material-region-opportunities- and-forecasts-2016-2021
Unit 3 of B pharm..Sem 6th Herbal cosmetics ,market overview, sources of description of raw material of herbal ,waxes,gum colour, perfume, protective agent , bleaching agent, preservatives
Classification of Sunscreens and SPF and Role of herbs in cosmetics:Priya Patil
Sun protection,
Classification of Sunscreens and SPF.
Role of herbs in cosmetics:
Skin Care: Aloe and turmeric
Hair care: Henna and amla.
Oral care: Neem and clove
The function of surfactants in cosmeticsalfachemistry
This article mainly introduces the function of surfactants in cosmetics. Visit https://www.alfa-chemistry.com/products/surfactant-124.htm for more information.
HERBAL DRUG TECHNOLOGY
Herbal Cosmetics
Sources and description of raw materials of herbal origin used via, fixed oils, waxes, gums
colours, perfumes, protective agents, bleaching agents, antioxidants in products such as skin
care, hair care and oral hygiene products.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
2. Colour Cosmetics
Colorants are ingredients that, alone or in combination with
other ingredients, impart or alter the color of the product.
3. Color Cosmetics
• Colors in cosmetics is contributed by an extensive range of dyes and
pigments.
• A Dye is a soluble coloring agent. It colors a product by dissolving in it. It
colors the skin by penetrating the surface.
• A Pigment is an insoluble powder color. These color the skin by coating it
with a film of pigment. Because pigments not actually absorbed by skin, so
easily cleansed away.
4. Why is it used in cosmetics and personal care
products?
Colorants are used to make products attractive and appealing.
Types :
Cosmetic colorants are classified as either organic or inorganic.
Organic colors are synthetic, chemically very complex molecule, are available
as either water soluble, oil soluble. Water soluble dyes are used for coloring
soaps, lotions, creams, powders, salts, etc. Natural materials used to color
cosmetics, like carrot oil, beet extract and henna, are also considered
5. Types
Inorganic colorants are composed of insoluble metallic compounds derived
from natural sources or are synthesized.
The following are inorganic pigments commonly used in makeup.
1. Chromium Dioxides
2. Iron Oxides.
6. White Pigments
White pigments are widely used in all cosmetics. Titanium
Dioxide and Zinc Oxide are the most commonly used in
cosmetics.
7. White Pigments
• Titanium Dioxide (CI 77891)-Titanium Dioxide is used to impart a
whiteness to color cosmetics and it helps to increase the opacity, and reduce
the transparency of a product formula. . Also, it acts as a preservative and
sunscreen by reflecting light.
• Zinc Oxide (CI 77947)—Zinc Oxide, a white powder, is used in a wide
range of cosmetics.
9. Isopropyl alcohol, Butyl alcohol, Cetyl alcohol
• A cheap filler ingredient, a preservative, a carrier ingredient to carry the other
active ingredients into the skin cells, or to help evaporate the oils used in the
product.
• Alcohol in cosmetics typically consists of one or more of three types of
chemical additives: ethyl, isopropyl and methyl.
• Isopropyl alcohol is found in most hand lotions, hair color rinses, body
rubs, after-shave, fragrances and many other cosmetics.
10. Cetyl Alcohol
• Cetyl alcohol is a long chain alcohol which is solid. It is also not absorbed
through the skin when applied as a cream.
12. Waxes
• Waxes are a diverse class of organic compounds that are hydrophobic. Waxes are insoluble
in water but soluble in organic, nonpolar solvents.
• Waxes are synthesized by many plants and animals. Those of animal origin typically consist
of wax esters derived from a variety of carboxylic acids and fatty alcohols .E.g
• Beeswax - produced by honey bees
• Chinese wax - produced by the scale insect
• Lanolin (wool wax) - from the sebaceous glands of sheep
Honeybees produce a natural wax, secreting it from glands on the sides of their bodies. It is
natural and non-toxic.
13. Uses of Bee wax
• Humectant: It attract water molecules, helping to keep skin hydrated over time.
• Fragrance: Beeswax has a natural honey fragrance, and is a favorite in soaps and
perfumes because of its pleasant, light aroma.
• Protective: When applied to the skin, beeswax forms a protective barrier that helps
protect it from environmental assaults, while also holding in moisture and reducing
dryness. This is one of the reasons beeswax is often used in lip balms.
• Thickening agent: which means that it can help thicken creams to make them
easier to use and more spreadable on the skin.
.
14. Sunscreens
Sunscreen, also known as sunscream, is a lotion, spray, gel or
other topical product that absorbs or reflects some of the sun's
ultraviolet (UV) radiation and thus helps protect against
sunburn
15. Organic and inorganic sunscreens
• “Mineral” sunscreens typically refer to zinc oxide and titanium dioxide,
which are chemical compounds labeled “inorganic” because they do not
contain carbon atoms in their overall structure.
• ‘Chemical” sunscreens are made up of carbon-containing molecules that
absorb light, and because they contain carbon, chemists refer to them as
“organic.”
Example:
Ethylhexyl salicylate, Oxybenzone, Titanium and Zinc oxide.
16. Oxybenzone
• When an organic molecule has a lot of double bonds, it’s good at absorbing
UV light, the same light that we are trying to block using sunlight. This is
what makes oxybenzone a good sunscreen.
• Oxybenzone is a clear sunscreen, meaning that it is relatively easy to apply
and does not have a white appearance. Most importantly, oxybenzone
absorbs UV light and protects skin from UV damage, which makes it a good
sunscreen.
17. Zinc oxide and Titanium dioxide sunscreen
• Zinc oxide and titanium oxide sunscreens are also both very effective at
blocking UV light from skin through a combination of scattering and
absorbing the UV light. Both of these compounds are white and produce an
opaque appearance on the skin.
18. Antioxidants
An antioxidant is a molecule that inhibits the oxidation of
other molecules. Oxidation is a chemical reaction that can
produce free radicals, leading to chain reactions that may
damage cells.
19. Example of Antioxidants
• Vitamin C: or Ascorbic acid is a monosaccharide oxidation-reduction
(redox) catalyst found in both animals and plants.
20. Vitamin E
Is a fat-soluble compound. It is also known as Vitamin E.
• What it does: Acts as an antioxidant, protecting the skin from free-radicals. As
well, it has anti-inflammatory properties and aids in moisturizing the skin.
• Where you’ll find it: Found in most beauty products; shampoo,
conditioner, skincare products, bath & body products, foundations, and even
mascara.
• sebum provides a delivery mechanism for vitamin E to the stratum corneum,
topical applications of vitamin E permeate the epidermis and dermis
21. Vitamin A
• Vitamin A is a group of unsaturated nutritional organic compounds that
includes retinol, retinal, retinoic acid.
• Vitamin A, and more specifically, retinoic acid, appears to maintain normal
skin health by switching on genes and differentiating keratinocytes (immature
skin cells) into mature epidermal cells.
22. Coenzyme Q10
• Coenzyme Q10, also known as ubiquinone, coenzyme Q. This fat-soluble
substance. This compound inhibits both the initiation and the propagation
of lipid and protein oxidation. It also regenerates other antioxidants such as
vitamin E.