This document summarizes a measurement of the t-tbar production cross section using data from proton-proton collisions at 7 TeV collected by the CMS experiment at the LHC. The analysis selects events with one high-pT muon or electron, missing transverse energy, and hadronic jets, requiring at least one jet to be tagged as originating from a b quark. The measured cross section is 150 ± 9 (stat) ± 17 (syst) ± 6 (lumi) pb, consistent with higher-order QCD calculations. Combining with a previous CMS dilepton measurement gives 154 ± 17 (stat + syst) ± 6 (lumi) pb.